Published in Am J Hum Genet on December 13, 2012
Lipoprotein lipase SNPs rs13702 and rs301 correlate with clinical outcome in chronic lymphocytic leukemia patients. PLoS One (2015) 1.37
MicroRNAs in the onset and development of cardiovascular disease. Clin Sci (Lond) (2014) 0.98
Prioritization of genetic variants in the microRNA regulome as functional candidates in genome-wide association studies. Hum Mutat (2013) 0.92
Dietary lipids modulate the expression of miR-107, an miRNA that regulates the circadian system. Mol Nutr Food Res (2015) 0.92
MiR-410 is overexpressed in liver and colorectal tumors and enhances tumor cell growth by silencing FHL1 via a direct/indirect mechanism. PLoS One (2014) 0.86
An APOA5 3' UTR variant associated with plasma triglycerides triggers APOA5 downregulation by creating a functional miR-485-5p binding site. Am J Hum Genet (2014) 0.86
The effects of a MAP2K5 microRNA target site SNP on risk for anxiety and depressive disorders. Am J Med Genet B Neuropsychiatr Genet (2014) 0.80
Needles in the genetic haystack of lipid disorders: single nucleotide polymorphisms in the microRNA regulome. J Lipid Res (2013) 0.80
Lipoprotein lipase gene sequencing and plasma lipid profile. J Lipid Res (2013) 0.78
Non-coding RNAs and lipid metabolism. Int J Mol Sci (2014) 0.78
Personalized nutrition and cardiovascular disease prevention: From Framingham to PREDIMED. Adv Nutr (2014) 0.78
Nutritional Genomics and the Mediterranean Diet's Effects on Human Cardiovascular Health. Nutrients (2016) 0.77
Genome-wide identification of microRNA-related variants associated with risk of Alzheimer's disease. Sci Rep (2016) 0.77
MicroRNA associated with dyslipidemia and coronary disease in humans. Physiol Genomics (2013) 0.76
Resequencing of LPL in African Blacks and associations with lipoprotein-lipid levels. Eur J Hum Genet (2015) 0.75
Genome-Wide Association Study Reveals Four Loci for Lipid Ratios in the Korean Population and the Constitutional Subgroup. PLoS One (2017) 0.75
Advances in Integrating Traditional and Omic Biomarkers When Analyzing the Effects of the Mediterranean Diet Intervention in Cardiovascular Prevention. Int J Mol Sci (2016) 0.75
How Gene Networks Can Uncover Novel CVD Players. Curr Cardiovasc Risk Rep (2014) 0.75
IRS-2 Partially Compensates for the Insulin Signal Defects in IRS-1(-/-) Mice Mediated by miR-33. Mol Cells (2017) 0.75
Nutrition, microRNAs, and Human Health. Adv Nutr (2017) 0.75
Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics (2004) 125.23
A map of human genome variation from population-scale sequencing. Nature (2010) 121.13
MicroRNAs: target recognition and regulatory functions. Cell (2009) 92.17
The International HapMap Project. Nature (2003) 73.65
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A (2009) 54.68
A mammalian microRNA expression atlas based on small RNA library sequencing. Cell (2007) 34.03
A map of recent positive selection in the human genome. PLoS Biol (2006) 29.19
Principles of microRNA-target recognition. PLoS Biol (2005) 23.70
A genome-wide association study of global gene expression. Nat Genet (2007) 22.98
METAL: fast and efficient meta-analysis of genomewide association scans. Bioinformatics (2010) 21.21
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet (2008) 12.32
Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts. Circ Cardiovasc Genet (2009) 8.42
Untranslated regions of mRNAs. Genome Biol (2002) 8.03
Genetic susceptibility to death from coronary heart disease in a study of twins. N Engl J Med (1994) 7.47
Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites. Genome Biol (2010) 7.15
Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides. Nat Genet (2008) 6.06
A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain. Genome Res (2004) 5.77
SNPinfo: integrating GWAS and candidate gene information into functional SNP selection for genetic association studies. Nucleic Acids Res (2009) 5.40
MicroRNA target site polymorphisms and human disease. Trends Genet (2008) 5.32
Human polymorphism at microRNAs and microRNA target sites. Proc Natl Acad Sci U S A (2007) 4.87
PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene. EMBO J (1996) 4.11
Lipoprotein lipase: genetics, lipid uptake, and regulation. J Lipid Res (2002) 4.09
Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol (2010) 4.08
Regulation of mRNA translation by 5'- and 3'-UTR-binding factors. Trends Biochem Sci (2003) 3.92
Principles for the post-GWAS functional characterization of cancer risk loci. Nat Genet (2011) 3.73
Recombinational and mutational hotspots within the human lipoprotein lipase gene. Am J Hum Genet (2000) 2.83
Lipoprotein lipase: structure, function, regulation, and role in disease. J Mol Med (Berl) (2002) 2.70
Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies. Diabetes Care (2010) 2.14
A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. Diabetes (2011) 2.09
MiRNA expression profile of human subcutaneous adipose and during adipocyte differentiation. PLoS One (2010) 1.89
Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study. PLoS Genet (2009) 1.75
MicroRNA-758 regulates cholesterol efflux through posttranscriptional repression of ATP-binding cassette transporter A1. Arterioscler Thromb Vasc Biol (2011) 1.54
Lipoprotein lipase: physiology, biochemistry, and molecular biology. Front Biosci (2001) 1.48
Complement protein C1q-mediated neuroprotection is correlated with regulation of neuronal gene and microRNA expression. J Neurosci (2011) 1.41
The PLIN4 variant rs8887 modulates obesity related phenotypes in humans through creation of a novel miR-522 seed site. PLoS One (2011) 1.28
A genome-wide survey for SNPs altering microRNA seed sites identifies functional candidates in GWAS. BMC Genomics (2011) 1.25
Nutritional genomics. Annu Rev Genomics Hum Genet (2004) 1.22
Associations between HDL-cholesterol and polymorphisms in hepatic lipase and lipoprotein lipase genes are modified by dietary fat intake in African American and White adults. Atherosclerosis (2006) 1.15
On beyond GWAS. Nat Genet (2010) 1.08
The acute phase response stimulates the expression of angiopoietin like protein 4. Biochem Biophys Res Commun (2009) 1.07
MicroRNA-29a regulates pro-inflammatory cytokine secretion and scavenger receptor expression by targeting LPL in oxLDL-stimulated dendritic cells. FEBS Lett (2011) 1.04
Dietary long-chain n-3 PUFAs increase LPL gene expression in adipose tissue of subjects with an atherogenic lipoprotein phenotype. J Lipid Res (2002) 1.01
A Database of Gene-Environment Interactions Pertaining to Blood Lipid Traits, Cardiovascular Disease and Type 2 Diabetes. J Data Mining Genomics Proteomics (2011) 0.98
Andes virus regulation of cellular microRNAs contributes to hantavirus-induced endothelial cell permeability. J Virol (2010) 0.98
A common truncation variant of lipoprotein lipase (Ser447X) confers protection against coronary heart disease: the Framingham Offspring Study. Clin Genet (1999) 0.96
Identification of microRNAs with a role in glucose stimulated insulin secretion by expression profiling of MIN6 cells. Biochem Biophys Res Commun (2010) 0.95
The lipoprotein lipase (LPL) S447X gain of function variant involves increased mRNA translation. Atherosclerosis (2011) 0.93
Associations of lipoprotein lipase gene polymorphisms with longitudinal plasma lipid trends in young adults: The Coronary Artery Risk Development in Young Adults (CARDIA) study. Circ Cardiovasc Genet (2010) 0.93
Gene-diet interaction in determining plasma lipid response to dietary intervention. Atherosclerosis (1995) 0.91
Transgenic mice expressing lipoprotein lipase in adipose tissue. Absence of the proximal 3'-untranslated region causes translational upregulation. J Biol Chem (2003) 0.91
Common sequence variants of lipoprotein lipase: standardized studies of in vitro expression and catalytic function. Biochim Biophys Acta (1996) 0.91
The 3' untranslated region of the lipoprotein lipase gene: haplotype structure and association with post-heparin plasma lipase activity. J Clin Endocrinol Metab (2005) 0.90
Translational regulation of lipoprotein lipase by epinephrine involves a trans-acting binding protein interacting with the 3' untranslated region. J Biol Chem (1997) 0.89
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science (2007) 37.88
Multi-Ethnic Study of Atherosclerosis: objectives and design. Am J Epidemiol (2002) 35.63
Heart disease and stroke statistics--2012 update: a report from the American Heart Association. Circulation (2011) 31.98
Heart disease and stroke statistics--2013 update: a report from the American Heart Association. Circulation (2012) 30.79
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet (2008) 30.20
Heart disease and stroke statistics--2011 update: a report from the American Heart Association. Circulation (2010) 30.07
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Heart disease and stroke statistics--2014 update: a report from the American Heart Association. Circulation (2013) 28.02
Heart disease and stroke statistics--2010 update: a report from the American Heart Association. Circulation (2009) 27.89
Strong association of de novo copy number mutations with autism. Science (2007) 27.84
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science (2006) 27.49
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. N Engl J Med (2006) 23.83
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Heart disease and stroke statistics--2015 update: a report from the American Heart Association. Circulation (2014) 22.74
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat Genet (2008) 20.73
Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet (2008) 20.66
A common allele on chromosome 9 associated with coronary heart disease. Science (2007) 20.37
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet (2007) 19.08
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet (2010) 17.38
Evolution and functional impact of rare coding variation from deep sequencing of human exomes. Science (2012) 17.12
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Characterizing the cancer genome in lung adenocarcinoma. Nature (2007) 16.48
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature (2012) 16.13
Replicating genotype-phenotype associations. Nature (2007) 16.11
Heart disease and stroke statistics--2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation (2008) 15.35
Cystatin C and the risk of death and cardiovascular events among elderly persons. N Engl J Med (2005) 15.30
Gait speed and survival in older adults. JAMA (2011) 15.01
Long-term exposure to air pollution and incidence of cardiovascular events in women. N Engl J Med (2007) 14.90
Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL. Nat Genet (2007) 13.78
Patterns and rates of exonic de novo mutations in autism spectrum disorders. Nature (2012) 13.71
Defining and setting national goals for cardiovascular health promotion and disease reduction: the American Heart Association's strategic Impact Goal through 2020 and beyond. Circulation (2010) 13.28
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25