Published in Lab Invest on December 12, 2011
CD133: a cancer stem cells marker, is used in colorectal cancers. World J Gastroenterol (2013) 1.15
CD133: to be or not to be, is this the real question? Am J Transl Res (2013) 1.12
Cancer stem cells in colorectal cancer from pathogenesis to therapy: controversies and perspectives. World J Gastroenterol (2014) 0.90
Cancer-associated fibroblasts connect metastasis-promoting communication in colorectal cancer. Front Oncol (2015) 0.87
Fibroblasts induce expression of FGF4 in ovarian cancer stem-like cells/cancer-initiating cells and upregulate their tumor initiation capacity. Lab Invest (2014) 0.86
Phenotypic diversity of patient-derived melanoma populations in stem cell medium. Lab Invest (2015) 0.84
CD133-positive tumor cell content is a predictor of early recurrence in colorectal cancer. J Gastrointest Oncol (2014) 0.83
A metabolic signature of colon cancer initiating cells. Conf Proc IEEE Eng Med Biol Soc (2014) 0.81
Priming cancer cells for drug resistance: role of the fibroblast niche. Front Biol (Beijing) (2014) 0.80
Major Protein of Carcinoembryonic Antigen Gene Family - CD66c, A Novel Marker in Colon Carcinoma. J Clin Diagn Res (2016) 0.77
Identification of a novel subpopulation of tumor-initiating cells from gemcitabine-resistant pancreatic ductal adenocarcinoma patients. PLoS One (2013) 0.75
Iterative sorting reveals CD133+ and CD133- melanoma cells as phenotypically distinct populations. BMC Cancer (2016) 0.75
Remodeling of energy metabolism by a ketone body and medium-chain fatty acid suppressed the proliferation of CT26 mouse colon cancer cells. Oncol Lett (2017) 0.75
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature (2006) 24.52
Identification and expansion of human colon-cancer-initiating cells. Nature (2006) 24.44
Identification of a cancer stem cell in human brain tumors. Cancer Res (2003) 24.02
Fibroblasts in cancer. Nat Rev Cancer (2006) 18.95
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell (2005) 18.20
Efficient tumour formation by single human melanoma cells. Nature (2008) 16.35
Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell (2007) 14.87
Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res (2005) 13.89
Macrophages: obligate partners for tumor cell migration, invasion, and metastasis. Cell (2006) 13.79
Phenotypic characterization of human colorectal cancer stem cells. Proc Natl Acad Sci U S A (2007) 13.58
Stromal fibroblasts in cancer initiation and progression. Nature (2004) 11.69
Tumor growth need not be driven by rare cancer stem cells. Science (2007) 10.34
Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium. Cancer Res (1999) 8.63
AC133, a novel marker for human hematopoietic stem and progenitor cells. Blood (1997) 7.84
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment. Nat Cell Biol (2010) 7.73
The role of myeloid cells in the promotion of tumour angiogenesis. Nat Rev Cancer (2008) 7.40
Tumor stroma and regulation of cancer development. Annu Rev Pathol (2006) 6.66
CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors. J Clin Invest (2008) 5.96
Identification and characterization of tumorigenic liver cancer stem/progenitor cells. Gastroenterology (2007) 5.75
CXCL12 (SDF-1)/CXCR4 pathway in cancer. Clin Cancer Res (2010) 5.42
Cancer-associated stromal fibroblasts promote pancreatic tumor progression. Cancer Res (2008) 5.21
A novel five-transmembrane hematopoietic stem cell antigen: isolation, characterization, and molecular cloning. Blood (1997) 5.04
CD133, a novel marker for human prostatic epithelial stem cells. J Cell Sci (2004) 4.76
Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity. Proc Natl Acad Sci U S A (2008) 4.60
CD133 positive hepatocellular carcinoma cells possess high capacity for tumorigenicity. Int J Cancer (2007) 3.65
CD44 is of functional importance for colorectal cancer stem cells. Clin Cancer Res (2008) 3.40
The stroma reaction myofibroblast: a key player in the control of tumor cell behavior. Int J Dev Biol (2004) 3.34
The chemokine receptor CXCR4 is required for outgrowth of colon carcinoma micrometastases. Cancer Res (2003) 3.03
Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition. Cancer Res (2009) 2.93
Cytokeratins 20 and 7 as biomarkers: usefulness in discriminating primary from metastatic adenocarcinoma. Eur J Cancer (2002) 2.28
CD133 expression is an independent prognostic marker for low survival in colorectal cancer. Br J Cancer (2008) 2.23
A frameshift mutation in prominin (mouse)-like 1 causes human retinal degeneration. Hum Mol Genet (2000) 1.87
Characterization of the intestinal cancer stem cell marker CD166 in the human and mouse gastrointestinal tract. Gastroenterology (2010) 1.86
CXCR4 antagonist inhibits stromal cell-derived factor 1-induced migration and invasion of human pancreatic cancer. Mol Cancer Ther (2004) 1.74
The cancer stem cell marker CD133 has high prognostic impact but unknown functional relevance for the metastasis of human colon cancer. J Pathol (2009) 1.67
Practical design criteria for a dynamic ratio imaging system. Cell Calcium (1990) 1.62
Biological and genetic characteristics of tumor-initiating cells in colon cancer. Ann Surg Oncol (2007) 1.62
Stromal cell-derived factor-1/chemokine (C-X-C motif) ligand 12 stimulates human hepatoma cell growth, migration, and invasion. Mol Cancer Res (2007) 1.53
New insights into the cell biology of hematopoietic progenitors by studying prominin-1 (CD133). Cells Tissues Organs (2007) 1.48
IL-4-mediated drug resistance in colon cancer stem cells. Cell Cycle (2007) 1.29
Cholinergic receptor up-regulates COX-2 expression and prostaglandin E(2) production in colon cancer cells. Carcinogenesis (2000) 1.24
Cells with characteristics of cancer stem/progenitor cells express the CD133 antigen in human endometrial tumors. Clin Cancer Res (2009) 1.17
Beta8 integrin regulates neurogenesis and neurovascular homeostasis in the adult brain. J Cell Sci (2009) 1.15
Tumour CD133 mRNA expression and clinical outcome in surgically resected colorectal cancer patients. Eur J Cancer (2009) 1.08
Frequency and pattern of expression of the stem cell marker CD133 have strong prognostic effect on the surgical outcome of colorectal cancer patients. Oncol Rep (2010) 1.03
Cyclophosphamide-induced cystitis increases bladder CXCR4 expression and CXCR4-macrophage migration inhibitory factor association. PLoS One (2008) 1.01
Elevated CD133, but not VEGF or EGFR, as a predictive marker of distant recurrence after preoperative chemoradiotherapy in rectal cancer. Oncol Rep (2009) 0.96
Gastrointestinal hormone receptors in primary human colorectal carcinomas. J Surg Res (2005) 0.95
Vitronectin in colorectal adenocarcinoma--synthesis by stromal cells in culture. Exp Cell Res (1994) 0.87
TRPC1 forms the stretch-activated cation channel in vertebrate cells. Nat Cell Biol (2005) 3.92
West Nile virus: where are we now? Lancet Infect Dis (2004) 3.49
The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase. Proc Natl Acad Sci U S A (2006) 2.17
Revisiting TRPC1 and TRPC6 mechanosensitivity. Pflugers Arch (2007) 1.81
Tumor-derived hydrogen sulfide, produced by cystathionine-β-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer. Proc Natl Acad Sci U S A (2013) 1.69
Negevirus: a proposed new taxon of insect-specific viruses with wide geographic distribution. J Virol (2012) 1.67
Comparison of the live attenuated yellow fever vaccine 17D-204 strain to its virulent parental strain Asibi by deep sequencing. J Infect Dis (2013) 1.51
Gastrin-releasing peptide is a growth factor for human neuroblastomas. Ann Surg (2002) 1.38
Transcriptional profiling of spinal cord injury-induced central neuropathic pain. J Neurochem (2005) 1.31
Differential regulation of BACE1 promoter activity by nuclear factor-kappaB in neurons and glia upon exposure to beta-amyloid peptides. J Neurosci Res (2007) 1.30
The National NeuroAIDS Tissue Consortium brain gene array: two types of HIV-associated neurocognitive impairment. PLoS One (2012) 1.27
Bombesin stimulates nuclear factor kappa B activation and expression of proangiogenic factors in prostate cancer cells. Cancer Res (2003) 1.27
Characterization of a novel Negevirus and a novel Bunyavirus isolated from Culex (Culex) declarator mosquitoes in Trinidad. J Gen Virol (2013) 1.26
Regulation of TRAIL expression by the phosphatidylinositol 3-kinase/Akt/GSK-3 pathway in human colon cancer cells. J Biol Chem (2002) 1.24
A WAVE2-Arp2/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens. Mol Biol Cell (2012) 1.22
Mice lacking alpha/beta and gamma interferon receptors are susceptible to junin virus infection. J Virol (2010) 1.20
Acyl-protein thioesterase 2 catalyzes the deacylation of peripheral membrane-associated GAP-43. PLoS One (2010) 1.18
α-catenin cytomechanics--role in cadherin-dependent adhesion and mechanotransduction. J Cell Sci (2014) 1.17
Cyclooxygenase-2 gene disruption attenuates the severity of acute pancreatitis and pancreatitis-associated lung injury. Gastroenterology (2002) 1.15
Gene expression profile of human lymphoid CEM cells sensitive and resistant to glucocorticoid-evoked apoptosis. Genomics (2003) 1.13
Identification of differentially activated cell-signaling networks associated with pichinde virus pathogenesis by using systems kinomics. J Virol (2006) 1.12
Gastrin stimulates cyclooxygenase-2 expression in intestinal epithelial cells through multiple signaling pathways. Evidence for involvement of ERK5 kinase and transactivation of the epidermal growth factor receptor. J Biol Chem (2002) 1.11
Identification of two functional domains within the arenavirus nucleoprotein. J Virol (2010) 1.10
Human polymorphic variants of the NEIL1 DNA glycosylase. J Biol Chem (2007) 1.10
Common marmosets (Callithrix jacchus) as a nonhuman primate model to assess the virulence of eastern equine encephalitis virus strains. J Virol (2008) 1.10
Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II. Pathophysiological and therapeutic aspects. Br J Pharmacol (2014) 1.10
Liver gene expression associated with diet and lesion development in atherosclerosis-prone mice: induction of components of alternative complement pathway. Physiol Genomics (2004) 1.08
Differential signaling networks induced by mild and lethal hemorrhagic fever virus infections. J Virol (2006) 1.07
Arenavirus entry occurs through a cholesterol-dependent, non-caveolar, clathrin-mediated endocytic mechanism. Virology (2007) 1.05
Functional interferon system is required for clearance of lassa virus. J Virol (2012) 1.05
E-cadherin supports steady-state Rho signaling at the epithelial zonula adherens. Differentiation (2013) 1.04
Curcumin inhibits neurotensin-mediated interleukin-8 production and migration of HCT116 human colon cancer cells. Clin Cancer Res (2006) 1.04
The role of protein kinase D in neurotensin secretion mediated by protein kinase C-alpha/-delta and Rho/Rho kinase. J Biol Chem (2004) 1.04
Role of gastrointestinal hormones in the proliferation of normal and neoplastic tissues. Endocr Rev (2003) 1.04
PKD3 is the predominant protein kinase D isoform in mouse exocrine pancreas and promotes hormone-induced amylase secretion. J Biol Chem (2008) 1.02
Quantification of activated NF-kappaB/RelA complexes using ssDNA aptamer affinity-stable isotope dilution-selected reaction monitoring-mass spectrometry. Mol Cell Proteomics (2011) 1.02
Human metapneumovirus M2-2 protein inhibits innate cellular signaling by targeting MAVS. J Virol (2012) 1.00
An animal model for the tickborne flavivirus--Omsk hemorrhagic fever virus. J Infect Dis (2004) 1.00
Implementation of a critical pathway for complicated gallstone disease: translation of population-based data into clinical practice. J Am Coll Surg (2011) 0.99
Selective targeting of the nuclear factor-kappaB pathway enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated pancreatic cancer cell death. Surgery (2002) 0.99
Targeting of a CCK(2) receptor splice variant with (111)In-labelled cholecystokinin-8 (CCK8) and (111)In-labelled minigastrin. Eur J Nucl Med Mol Imaging (2007) 0.98
Genistein treatment of cells inhibits arenavirus infection. Antiviral Res (2007) 0.98
Cortactin scaffolds Arp2/3 and WAVE2 at the epithelial zonula adherens. J Biol Chem (2014) 0.97
Cognitive enhancement with rosiglitazone links the hippocampal PPARγ and ERK MAPK signaling pathways. J Neurosci (2012) 0.97
Kolente virus, a rhabdovirus species isolated from ticks and bats in the Republic of Guinea. J Gen Virol (2013) 0.97
Identification of critical residues required for the mutation avoidance function of human MutY (hMYH) and implications in colorectal cancer. Cancer Lett (2004) 0.97
Multicomponent analysis of junctional movements regulated by myosin II isoforms at the epithelial zonula adherens. PLoS One (2011) 0.97
Equine amplification and virulence of subtype IE Venezuelan equine encephalitis viruses isolated during the 1993 and 1996 Mexican epizootics. Emerg Infect Dis (2003) 0.96
NH2 terminus of PTB-associated splicing factor binds to the porcine P450scc IGF-I response element. Am J Physiol Endocrinol Metab (2002) 0.96
Cytokine patterns in a comparative model of arenavirus haemorrhagic fever in guinea pigs. J Gen Virol (2008) 0.95
Thioaptamer decoy targeting of AP-1 proteins influences cytokine expression and the outcome of arenavirus infections. J Gen Virol (2007) 0.95
Apelin, a new enteric peptide: localization in the gastrointestinal tract, ontogeny, and stimulation of gastric cell proliferation and of cholecystokinin secretion. Endocrinology (2003) 0.95
Gastrointestinal hormone receptors in primary human colorectal carcinomas. J Surg Res (2005) 0.95
Early immunologic events at the tick-host interface. PLoS One (2012) 0.94
BMP2 inhibits TGF-β-induced pancreatic stellate cell activation and extracellular matrix formation. Am J Physiol Gastrointest Liver Physiol (2013) 0.94
Niakha virus: a novel member of the family Rhabdoviridae isolated from phlebotomine sandflies in Senegal. Virology (2013) 0.94
Gene networks in glucocorticoid-evoked apoptosis of leukemic cells. J Steroid Biochem Mol Biol (2003) 0.94
Gene expression profile of mouse white adipose tissue during inflammatory stress: age-dependent upregulation of major procoagulant factors. Aging Cell (2013) 0.93
Henipavirus pathogenesis in human respiratory epithelial cells. J Virol (2013) 0.93
Molecular markers of clonality and identity in Epstein-Barr virus-associated B-cell lymphoproliferative disease. J Med Virol (2004) 0.93
The use of abdominal computed tomography scan decreases the frequency of misdiagnosis in cases of suspected appendicitis. Am J Surg (2002) 0.93
Arboretum and Puerto Almendras viruses: two novel rhabdoviruses isolated from mosquitoes in Peru. J Gen Virol (2014) 0.92
Systems approaches to modeling chronic mucosal inflammation. Biomed Res Int (2013) 0.91
Expression of an IKKgamma splice variant determines IRF3 and canonical NF-kappaB pathway utilization in ssRNA virus infection. PLoS One (2009) 0.90
Gastrin, inflammation, and carcinogenesis. Curr Opin Endocrinol Diabetes Obes (2010) 0.90
Brain glucose transporter (Glut3) haploinsufficiency does not impair mouse brain glucose uptake. Brain Res (2011) 0.90
Prophylactic application of CpG oligonucleotides augments the early host response and confers protection in acute melioidosis. PLoS One (2012) 0.89
Phorbol ester-mediated neurotensin secretion is dependent on the PKC-alpha and -delta isoforms. Am J Physiol Gastrointest Liver Physiol (2002) 0.89
Selection of thioaptamers for diagnostics and therapeutics. Ann N Y Acad Sci (2006) 0.89
Disseminated acanthamoebiasis after lung transplantation. J Heart Lung Transplant (2005) 0.88
Attenuated and lethal variants of Pichindé virus induce differential patterns of NF-kappaB activation suggesting a potential target for novel therapeutics. Viral Immunol (2009) 0.88
Immortalization and characterization of human myometrial cells from term-pregnant patients using a telomerase expression vector. Mol Hum Reprod (2004) 0.88
Mesoniviruses are mosquito-specific viruses with extensive geographic distribution and host range. Virol J (2014) 0.87
Noggin attenuates cerulein-induced acute pancreatitis and impaired autophagy. Pancreas (2013) 0.87
First isolation of Aedes flavivirus in the Western Hemisphere and evidence of vertical transmission in the mosquito Aedes (Stegomyia) albopictus (Diptera: Culicidae). Virology (2013) 0.86
Alterations in stomach ghrelin production and in ghrelin-induced growth hormone secretion in the aged rat. Mech Ageing Dev (2004) 0.86
Gastrin-releasing peptide receptor in breast cancer mediates cellular migration and interleukin-8 expression. J Surg Res (2009) 0.86
Intrastrand DNA cross-links as tools for studying DNA replication and repair: two-, three-, and four-carbon tethers between the N(2) positions of adjacent guanines. Biochemistry (2002) 0.86
Variable penetrance of metabolic phenotypes and development of high-fat diet-induced adiposity in NEIL1-deficient mice. Am J Physiol Endocrinol Metab (2011) 0.86
Dual acylation is required for trafficking of growth-associated protein-43 (GAP-43) to endosomal recycling compartment via an Arf6-associated endocytic vesicular pathway. Biochem J (2009) 0.85
Exploring kinase inhibitors as therapies for human arenavirus infections. Future Virol (2008) 0.85
Pulmonary vascular permeability changes in an ovine model of methicillin-resistant Staphylococcus aureus sepsis. Crit Care (2009) 0.85
Itaya virus, a Novel Orthobunyavirus Associated with Human Febrile Illness, Peru. Emerg Infect Dis (2015) 0.85
SRC regulates constitutive internalization and rapid resensitization of a cholecystokinin 2 receptor splice variant. J Biol Chem (2005) 0.84
Cytodiagnosis in the autopsy suite: a tool for improving autopsy quality and resident education. Arch Pathol Lab Med (2007) 0.84
2-Bromopalmitate reduces protein deacylation by inhibition of acyl-protein thioesterase enzymatic activities. PLoS One (2013) 0.84
Agonist- and protein kinase C-induced phosphorylation have similar functional consequences for gastrin-releasing peptide receptor signaling via Gq. Mol Pharmacol (2003) 0.84
Endogenously produced hydrogen sulfide supports tumor cell growth and proliferation. Cell Cycle (2013) 0.83