Published in Cardiovasc Diabetol on December 14, 2011
Association of PPARγ2 gene variant Pro12Ala polymorphism with hypertension and obesity in the aboriginal Qatari population known for being consanguineous. Appl Clin Genet (2013) 0.97
Meta-analysis of association between the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-γ2 gene and diabetic retinopathy in Caucasians and Asians. Mol Vis (2012) 0.91
Single nucleotide polymorphisms (SNPs) involved in insulin resistance, weight regulation, lipid metabolism and inflammation in relation to metabolic syndrome: an epidemiological study. Cardiovasc Diabetol (2012) 0.86
Prevalence of angiotensin converting enzyme (ACE) gene insertion/deletion polymorphism in South Indian population with hypertension and chronic kidney disease. J Postgrad Med (2015) 0.80
Association of the variants in the PPARG gene and serum lipid levels: a meta-analysis of 74 studies. J Cell Mol Med (2014) 0.79
Lifestyle factors modify obesity risk linked to PPARG2 and FTO variants in an elderly population: a cross-sectional analysis in the SUN Project. Genes Nutr (2012) 0.78
Association of Angiotensin-Converting Enzyme and Glutathione S-Transferase Gene Polymorphisms with Body Mass Index among Hypertensive North Indians. Sultan Qaboos Univ Med J (2015) 0.77
Nutrigenomic Functions of PPARs in Obesogenic Environments. PPAR Res (2016) 0.76
Association of FTO and PPARG polymorphisms with obesity in Portuguese women. Diabetes Metab Syndr Obes (2013) 0.76
ACE Gene I/D Polymorphism and Obesity in 1,574 Patients with Type 2 Diabetes Mellitus. Dis Markers (2016) 0.75
Gender-specific genetic associations of polymorphisms in ACE, AKR1C2, FTO and MMP2 with weight gain over a 10-year period. Genes Nutr (2014) 0.75
Evaluation of Association of ADRA2A rs553668 and ACE I/D Gene Polymorphisms with Obesity Traits in the Setapak Population, Malaysia. Iran Red Crescent Med J (2016) 0.75
Association of MTTP gene variants with pediatric NAFLD: A candidate-gene-based analysis of single nucleotide variations in obese children. PLoS One (2017) 0.75
The Effect of Dried Glycyrrhiza Glabra L. Extract on Obesity Management with Regard to PPAR-γ2 (Pro12Ala) Gene Polymorphism in Obese Subjects Following an Energy Restricted Diet. Adv Pharm Bull (2017) 0.75
Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation (2005) 43.74
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J Biol Chem (1995) 13.34
An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest (1990) 10.35
Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care (1991) 9.95
A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Nat Genet (1998) 8.02
Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. Endocrinology (1996) 7.92
The organization, promoter analysis, and expression of the human PPARgamma gene. J Biol Chem (1997) 4.55
A rapid procedure for extracting genomic DNA from leukocytes. Nucleic Acids Res (1991) 3.89
Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels. Am J Hum Genet (1992) 3.33
Treatment of insulin resistance with peroxisome proliferator-activated receptor gamma agonists. J Clin Invest (2000) 2.80
Physiology and pathophysiology of the adipose tissue renin-angiotensin system. Hypertension (2000) 2.30
Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma. Diabetes (2003) 2.28
Biosynthesis of 15-deoxy-delta12,14-PGJ2 and the ligation of PPARgamma. J Clin Invest (2003) 2.27
Transcriptional control of adipogenesis. Annu Rev Nutr (2000) 2.14
Molecular scanning of the human peroxisome proliferator activated receptor gamma (hPPAR gamma) gene in diabetic Caucasians: identification of a Pro12Ala PPAR gamma 2 missense mutation. Biochem Biophys Res Commun (1997) 1.96
ACE gene insertion/deletion polymorphism associated with 1998 World Health Organization definition of metabolic syndrome in Chinese type 2 diabetic patients. Diabetes Care (2002) 1.71
Mice lacking angiotensin-converting enzyme have increased energy expenditure, with reduced fat mass and improved glucose clearance. Proc Natl Acad Sci U S A (2008) 1.51
The association between the peroxisome proliferator-activated receptor-gamma2 (PPARG2) Pro12Ala gene variant and type 2 diabetes mellitus: a HuGE review and meta-analysis. Am J Epidemiol (2010) 1.49
Effect of the peroxisome proliferator activated receptor-gamma gene Pro12Ala variant on body mass index: a meta-analysis. J Med Genet (2003) 1.48
Enhancement of adipocyte differentiation by an insulin-sensitizing agent. Mol Pharmacol (1992) 1.46
Leptin deficiency unmasks the deleterious effects of impaired peroxisome proliferator-activated receptor gamma function (P465L PPARgamma) in mice. Diabetes (2006) 1.39
Heritabilities of the metabolic syndrome and its components in the Northern Manhattan Family Study. Diabetologia (2005) 1.20
Effect of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor gamma-2 gene on adiposity, insulin sensitivity and lipid profile in the Spanish population. Eur J Endocrinol (2002) 1.09
Angiotensin II as a trophic factor of white adipose tissue: stimulation of adipose cell formation. Endocrinology (2001) 1.07
Genetic variation in fatty acid-binding protein-4 and peroxisome proliferator-activated receptor gamma interactively influence insulin sensitivity and body composition in males. Metabolism (2004) 1.07
Inverse effects of the PPAR(gamma)2 Pro12Ala polymorphism on measures of adiposity over 15 years in African Americans and whites. The CARDIA study. Metabolism (2005) 1.00
The Pro12Ala variant of peroxisome proliferator-activated receptor-gamma2 (PPAR-gamma2) is associated with measures of obesity in Mexican Americans. Int J Obes Relat Metab Disord (2000) 0.98
Interaction between PPARgamma2 variants and gender on the modulation of body weight. Obesity (Silver Spring) (2008) 0.97
Gene-gene interaction between PPAR gamma 2 and ADR beta 3 increases obesity risk in children and adolescents. Int J Obes Relat Metab Disord (2004) 0.96
ACE variants interact with the RAS pathway to confer risk and protection against type 2 diabetic nephropathy. DNA Cell Biol (2009) 0.95
PPARgamma gene C161T substitution alters lipid profile in Chinese patients with coronary artery disease and type 2 diabetes mellitus. Cardiovasc Diabetol (2010) 0.93
The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene on glucose/insulin metabolism interact with prenatal exposure to famine. Diabetes Care (2006) 0.92
Activation of nuclear receptors by prostaglandins. Thromb Res (2003) 0.90
An analysis of peroxisome proliferator-activated receptor gamma (PPAR-gamma 2) Pro12Ala polymorphism distribution and prevalence of type 2 diabetes mellitus (T2DM) in world populations in relation to dietary habits. Nutr Metab Cardiovasc Dis (2007) 0.89
Increased frequency of angiotensin-converting enzyme DD genotype in patients with type 2 diabetes in Taiwan. Nephrol Dial Transplant (2000) 0.89
The Ala allele in the PPAR-gamma2 gene is associated with reduced risk of type 2 diabetes mellitus in Caucasians and improved insulin sensitivity in overweight subjects. Br J Nutr (2010) 0.88
ACE I/D genotype, adiposity, and blood pressure in children. Cardiovasc Diabetol (2009) 0.87
The association of dimethylarginine dimethylaminohydrolase 1 gene polymorphism with type 2 diabetes: a cohort study. Cardiovasc Diabetol (2011) 0.87
Polymorphism in the PPARgamma2 and beta2-adrenergic genes and diet lipid effects on body composition, energy expenditure and eating behavior of obese women. Appetite (2007) 0.86
PPARs in the Renal Regulation of Systemic Blood Pressure. PPAR Res (2010) 0.82
Polymorphisms of angiotensin-converting enzyme and angiotensinogen genes in type 2 diabetic sibships in relation to albumin excretion rate. Am J Kidney Dis (1999) 0.81
Effect of ENPP1/PC-1-K121Q and PPARgamma-Pro12Ala polymorphisms on the genetic susceptibility to T2D in the Tunisian population. Diabetes Res Clin Pract (2008) 0.80
The ACE insertion/deletion polymorphism is not associated with the metabolic syndrome (WHO Definition) in Brazilian type 2 diabetic patients. Diabetes Care (2002) 0.78
Interactions of the PPARγ2 polymorphism with fat intake affecting energy metabolism and nutritional outcomes in obese women. Ann Nutr Metab (2010) 0.77
Association between ACE-D/D polymorphism and hypertension in type II diabetic subjects. J Hum Hypertens (1994) 0.77
Executive function correlates with walking speed in older persons: the InCHIANTI study. J Am Geriatr Soc (2005) 2.75
Predictive value of the Short Physical Performance Battery following hospitalization in older patients. J Gerontol A Biol Sci Med Sci (2010) 1.85
Association of tumor necrosis factor-related apoptosis-inducing ligand with total and cardiovascular mortality in older adults. Atherosclerosis (2010) 1.71
Autosomal recessive hypercholesterolaemia in Sardinia, Italy, and mutations in ARH: a clinical and molecular genetic analysis. Lancet (2002) 1.69
The human lipodystrophy gene BSCL2/seipin may be essential for normal adipocyte differentiation. Diabetes (2008) 1.67
Anaemia increases the risk of dementia in cognitively intact elderly. Neurobiol Aging (2006) 1.65
Risk factors for short-term mortality in older subjects with acute ischemic stroke. Gerontology (2006) 1.49
Extracellular ATP causes ROCK I-dependent bleb formation in P2X7-transfected HEK293 cells. Mol Biol Cell (2003) 1.49
Prescription of antithrombotic therapy in older patients hospitalized for transient ischemic attack and ischemic stroke: the GIFA study. Stroke (2004) 1.45
Relationship of alcohol intake with inflammatory markers and plasminogen activator inhibitor-1 in well-functioning older adults: the Health, Aging, and Body Composition study. Circulation (2004) 1.41
Role of muscle mass and muscle quality in the association between diabetes and gait speed. Diabetes Care (2012) 1.33
Molecular mechanisms of autosomal recessive hypercholesterolemia. Hum Mol Genet (2002) 1.33
Prevalence and clinical correlates of sarcopenia in community-dwelling older people: application of the EWGSOP definition and diagnostic algorithm. J Gerontol A Biol Sci Med Sci (2013) 1.33
Decreased brown adipocyte recruitment and thermogenic capacity in mice with impaired peroxisome proliferator-activated receptor (P465L PPARgamma) function. Endocrinology (2006) 1.29
Performance-based functional assessment in older hospitalized patients: feasibility and clinical correlates. J Gerontol A Biol Sci Med Sci (2008) 1.28
Progression of lower-extremity disability in older women with diabetes: the Women's Health and Aging Study. Diabetes Care (2003) 1.24
Activation of microglia by amyloid {beta} requires P2X7 receptor expression. J Immunol (2009) 1.23
High interleukin-6 plasma levels are associated with low HDL-C levels in community-dwelling older adults: the InChianti study. Atherosclerosis (2006) 1.13
Characteristics of nondisabled older patients developing new disability associated with medical illnesses and hospitalization. J Gen Intern Med (2007) 1.13
Elevated C-reactive protein levels and metabolic syndrome in the elderly: The role of central obesity data from the InChianti study. Atherosclerosis (2008) 1.12
Laser ablation for hepatic metastases from neuroendocrine tumors. AJR Am J Roentgenol (2015) 1.10
Type 2 diabetes and risk for functional decline and disability in older persons. Curr Diabetes Rev (2010) 1.08
High-density lipoprotein cholesterol and objective measures of lower extremity performance in older nondisabled persons: the InChianti study. J Am Geriatr Soc (2008) 1.06
Resection vs thermal ablation of small hepatocellular carcinoma: What's the first choice? World J Radiol (2013) 1.04
Association of hormonal dysregulation with metabolic syndrome in older women: data from the InCHIANTI study. Am J Physiol Endocrinol Metab (2006) 1.00
Plasma soluble gp130 levels are increased in older subjects with metabolic syndrome. The role of insulin resistance. Atherosclerosis (2010) 0.96
Uric acid and dementia in community-dwelling older persons. Dement Geriatr Cogn Disord (2009) 0.93
Systemic oxidative stress in older patients with mild cognitive impairment or late onset Alzheimer's disease. Curr Alzheimer Res (2013) 0.93
Moderate alcohol intake and risk of functional decline: the Health, Aging, and Body Composition study. J Am Geriatr Soc (2009) 0.90
Low cholesterol levels are associated with short-term mortality in older patients with ischemic stroke. J Gerontol A Biol Sci Med Sci (2004) 0.90
Relationship between vitamin D and inflammatory markers in older individuals. Age (Dordr) (2014) 0.90
Anemia and recovery from disability in activities of daily living in hospitalized older persons. J Am Geriatr Soc (2006) 0.88
Effect of a standardized grape seed extract on low-density lipoprotein susceptibility to oxidation in heavy smokers. Metabolism (2003) 0.88
SHBG, sex hormones, and inflammatory markers in older women. J Clin Endocrinol Metab (2011) 0.88
Underrecognition and undertreatment of dementia in Italian nursing homes. J Am Med Dir Assoc (2012) 0.88
Role of ultrasonography and contrast-enhanced ultrasonography in a case of Krukenberg tumor. World J Radiol (2013) 0.87
Body mass index, body cell mass, and 4-year all-cause mortality risk in older nursing home residents. J Am Geriatr Soc (2004) 0.87
Defective P2Y purinergic receptor function: A possible novel mechanism for impaired glucose transport. J Cell Physiol (2003) 0.87
Consensus Document on substitution therapy with DHEA in the elderly. Aging Clin Exp Res (2006) 0.86
Lipoprotein(a), inflammation, and peripheral arterial disease in a community-based sample of older men and women (the InCHIANTI study). Am J Cardiol (2010) 0.86
Anaphylactic shock and acute pulmonary edema after a single oral dose of acetazolamide. Am J Emerg Med (2002) 0.84
Association between anemia and physical disability in older patients: role of comorbidity. Aging Clin Exp Res (2006) 0.84
Determinants and clinical significance of plasma oxidized LDLs in older individuals. A 9 years follow-up study. Atherosclerosis (2012) 0.83
Association of soluble Tumor necrosis factor-Related Apoptosis-Inducing Ligand (TRAIL) with central adiposity and low-density lipoprotein cholesterol. PLoS One (2013) 0.83
Consensus Document on substitution therapy with testosterone in hypoandrogenic elderly men. Aging Clin Exp Res (2002) 0.83
Enhanced soluble CD40 ligand and Alzheimer's disease: evidence of a possible pathogenetic role. Neurobiol Aging (2006) 0.82
Actual concept of "probiotics": is it more functional to science or business? World J Gastroenterol (2013) 0.82
First case of 2 intraductal papillary mucinous tumors of both ventral and dorsal ducts in pancreas divisum. Pancreas (2010) 0.82
Total serum cholesterol and recovery from disability among hospitalized older adults. J Gerontol A Biol Sci Med Sci (2006) 0.82
Serum cholesterol levels and in-hospital mortality in the elderly. Am J Med (2003) 0.82
Effect of statins on LDL particle size in patients with familial combined hyperlipidemia: a comparison between atorvastatin and pravastatin. Nutr Metab Cardiovasc Dis (2005) 0.81
Plasma 24S-hydroxycholesterol levels in elderly subjects with late onset Alzheimer's disease or vascular dementia: a case-control study. BMC Neurol (2011) 0.81
Relationship between N-terminal pro-B-type natriuretic peptide plasma levels and renal function evaluated with different formulae in older adult subjects admitted because of dyspnea. Gerontology (2011) 0.81
Physical disability in the elderly with diabetes: epidemiology and mechanisms. Curr Diab Rep (2013) 0.81
Emotional vitality and change in lower extremity function after acute medical illness and hospitalization. J Am Geriatr Soc (2003) 0.80
Anemia, physical disability, and survival in older patients with heart failure. J Card Fail (2006) 0.80
Simvastatin, transdermal patch, and oral estrogen-progestogen preparation in early-postmenopausal hypercholesterolemic women: a randomized, placebo-controlled clinical trial. Metabolism (2002) 0.79
Treatment with angiotensin-converting enzyme inhibitors is associated with a reduction in short-term mortality in older patients with acute ischemic stroke. J Gerontol A Biol Sci Med Sci (2005) 0.78
Assessment of mobility status and risk of mobility disability in older persons. Curr Pharm Des (2014) 0.78
SHBG and endothelial function in older subjects. Int J Cardiol (2013) 0.77
PON-1 and ferroxidase activities in older patients with mild cognitive impairment, late onset Alzheimer's disease or vascular dementia. Clin Chem Lab Med (2015) 0.76
Eosinophilic gastroenteritis cured with Helicobacter pylori eradication: case report and review of literature. Helicobacter (2014) 0.76
Nonalcoholic fatty liver and metabolic syndrome in Italy: results from a multicentric study of the Italian Arteriosclerosis society. Acta Diabetol (2012) 0.76
Predictive value of admission N-terminal pro-B-type natriuretic peptide and renal function in older people hospitalized for dyspnoea. Dis Markers (2013) 0.75
Genetic factors associated with the absence of atherosclerosis in octogenarians. J Gerontol A Biol Sci Med Sci (2002) 0.75
Hypercholesterolemia and the ageing subject. Eur J Intern Med (2010) 0.75
In Memoriam. Obituary: Professor Andrea Mezzetti, MD (1949-2013). Nutr Metab Cardiovasc Dis (2013) 0.75
Pharmacotherapy of dyslipidemias in the adult population. Expert Opin Pharmacother (2010) 0.75
[Alcohol consumption and circulating markers of inflammation]. Recenti Prog Med (2005) 0.75
[Atrial natriuretic peptides: a new diagnostic tool for the internist]. Recenti Prog Med (2005) 0.75
Disease Progression in HIV Late Presenters: the Role of HIV Clinical Indicator Diseases Prior to HIV Diagnosis. Curr HIV Res (2016) 0.75
An unusual case of hyperammonemia in a 83-year-old woman. Aging Clin Exp Res (2007) 0.75
[Effect of the pharmacological antagonism of the endocannabinoid receptors on the sodium balance in liver cirrhosis]. Recenti Prog Med (2011) 0.75
[Intestinal cholesterol absorption: a pharmacological target for lowering of plasma cholesterol]. Ital Heart J Suppl (2004) 0.75
Lung cancer presenting with gastrointestinal symptoms: a tricky diagnosis. Dig Liver Dis (2009) 0.75
Pilot dietary study with normoproteic protein-redistributed plant-food diet and motor performance in patients with Parkinson's disease. Nutr Neurosci (2011) 0.75
[Dyslipidemia and global cardiovascular risk: treatment guidelines]. Ital Heart J (2003) 0.75
Virtual CT sonographically guided biopsy of a retroperitoneal mass in a patient with Erdheim-Chester disease. J Clin Ultrasound (2013) 0.75
The benefit and risk of testosterone replacement therapy in older men: effects on lipid metabolism. Acta Biomed (2010) 0.75
Combined measurement of serum albumin and high-density lipoprotein cholesterol strongly predicts mortality in frail older nursing-home residents. Aging Clin Exp Res (2004) 0.75
Prescription of anti-oedema agents and short-term mortality in older patients with acute ischaemic stroke. Drugs Aging (2004) 0.75
Serum Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Levels in Older Subjects with Dementia and Mild Cognitive Impairment. Dement Geriatr Cogn Disord (2016) 0.75