Quantification of increased cellularity during inflammatory demyelination.

PubWeight™: 2.05‹?› | Rank: Top 2%

🔗 View Article (PMC 3235568)

Published in Brain on December 01, 2011

Authors

Yong Wang1, Qing Wang, Justin P Haldar, Fang-Cheng Yeh, Mingqiang Xie, Peng Sun, Tsang-Wei Tu, Kathryn Trinkaus, Robyn S Klein, Anne H Cross, Sheng-Kwei Song

Author Affiliations

1: Department of Radiology, Washington University, St. Louis, MO 63110, USA.

Articles citing this

Spinal cord tract diffusion tensor imaging reveals disability substrate in demyelinating disease. Neurology (2013) 1.77

Excessive extracellular volume reveals a neurodegenerative pattern in schizophrenia onset. J Neurosci (2012) 1.69

Diffusion tensor imaging detects axonal injury in a mouse model of repetitive closed-skull traumatic brain injury. Neurosci Lett (2012) 1.19

Local mechanical properties of white matter structures in the human brain. Neuroimage (2013) 1.07

Estimation of extracellular volume from regularized multi-shell diffusion MRI. Med Image Comput Comput Assist Interv (2012) 1.06

A mathematical framework for the registration and analysis of multi-fascicle models for population studies of the brain microstructure. IEEE Trans Med Imaging (2013) 1.02

Longitudinal changes in free-water within the substantia nigra of Parkinson's disease. Brain (2015) 1.00

Improved in vivo diffusion tensor imaging of human cervical spinal cord. Neuroimage (2012) 0.99

Hockey Concussion Education Project, Part 2. Microstructural white matter alterations in acutely concussed ice hockey players: a longitudinal free-water MRI study. J Neurosurg (2014) 0.99

Increased free water in the substantia nigra of Parkinson's disease: a single-site and multi-site study. Neurobiol Aging (2014) 0.97

Histological correlation of diffusional kurtosis and white matter modeling metrics in cuprizone-induced corpus callosum demyelination. NMR Biomed (2014) 0.97

Quantifying white matter tract diffusion parameters in the presence of increased extra-fiber cellularity and vasogenic edema. Neuroimage (2014) 0.96

Differentiation and quantification of inflammation, demyelination and axon injury or loss in multiple sclerosis. Brain (2015) 0.96

Diffusion basis spectrum imaging detects and distinguishes coexisting subclinical inflammation, demyelination and axonal injury in experimental autoimmune encephalomyelitis mice. NMR Biomed (2014) 0.96

Age effects and sex differences in human brain white matter of young to middle-aged adults: A DTI, NODDI, and q-space study. Neuroimage (2015) 0.94

Multi-Tissue Decomposition of Diffusion MRI Signals via L0 Sparse-Group Estimation. IEEE Trans Image Process (2016) 0.94

The effects of HIV and combination antiretroviral therapy on white matter integrity. AIDS (2012) 0.93

Isotropic non-white matter partial volume effects in constrained spherical deconvolution. Front Neuroinform (2014) 0.92

Imaging of spontaneous ventriculomegaly and vascular malformations in Wistar rats: implications for preclinical research. J Neuropathol Exp Neurol (2014) 0.91

Diffusion tensor imaging and related techniques in tuberous sclerosis complex: review and future directions. Future Neurol (2013) 0.91

Structural insights into the rodent CNS via diffusion tensor imaging. Trends Neurosci (2012) 0.90

Understanding disease processes in multiple sclerosis through magnetic resonance imaging studies in animal models. Neuroimage Clin (2014) 0.88

Characterizing brain tissue by assessment of the distribution of anisotropic microstructural environments in diffusion-compartment imaging (DIAMOND). Magn Reson Med (2015) 0.88

Nonconventional MRI and microstructural cerebral changes in multiple sclerosis. Nat Rev Neurol (2015) 0.87

Kurtosis analysis of neural diffusion organization. Neuroimage (2014) 0.86

In vivo imaging of neuroinflammation in schizophrenia. Schizophr Res (2015) 0.86

Abnormal Injury Response in Spontaneous Mild Ventriculomegaly Wistar Rat Brains: A Pathological Correlation Study of Diffusion Tensor and Magnetization Transfer Imaging in Mild Traumatic Brain Injury. J Neurotrauma (2016) 0.86

Optimization of a free water elimination two-compartment model for diffusion tensor imaging. Neuroimage (2014) 0.85

Cerebral white matter integrity during primary HIV infection. AIDS (2015) 0.85

Brain tissue compartment density estimated using diffusion-weighted MRI yields tissue parameters consistent with histology. Hum Brain Mapp (2015) 0.83

Oligodendrocyte lineage and subventricular zone response to traumatic axonal injury in the corpus callosum. J Neuropathol Exp Neurol (2013) 0.83

Radiological-pathological correlation of diffusion tensor and magnetization transfer imaging in a closed head traumatic brain injury model. Ann Neurol (2016) 0.82

Gray matter alterations in early aging: a diffusion magnetic resonance imaging study. Hum Brain Mapp (2013) 0.82

Imaging outcomes for trials of remyelination in multiple sclerosis. J Neurol Neurosurg Psychiatry (2014) 0.82

N-acetyl-aspartate levels correlate with intra-axonal compartment parameters from diffusion MRI. Neuroimage (2015) 0.81

Quantification of cell size using temporal diffusion spectroscopy. Magn Reson Med (2015) 0.81

Free-water and BOLD imaging changes in Parkinson's disease patients chronically treated with a MAO-B inhibitor. Hum Brain Mapp (2016) 0.80

Long-term effects of neonatal hypoxia-ischemia on structural and physiological integrity of the eye and visual pathway by multimodal MRI. Invest Ophthalmol Vis Sci (2014) 0.80

3D structure tensor analysis of light microscopy data for validating diffusion MRI. Neuroimage (2015) 0.80

Evaluation of white matter myelin water fraction in chronic stroke. Neuroimage Clin (2013) 0.80

Magnetic Resonance Imaging Biomarker of Axon Loss Reflects Cervical Spondylotic Myelopathy Severity. Spine (Phila Pa 1976) (2016) 0.80

Investigating Age-related changes in fine motor control across different effectors and the impact of white matter integrity. Neuroimage (2014) 0.80

Quantitative Evaluation of Rabbit Brain Injury after Cerebral Hemisphere Radiation Exposure Using Generalized q-Sampling Imaging. PLoS One (2015) 0.79

Localized diffusion magnetic resonance micro-imaging of the live mouse brain. Neuroimage (2014) 0.79

Remyelination Therapy in Multiple Sclerosis. Front Neurol (2015) 0.79

Assessing White Matter Microstructure in Brain Regions with Different Myelin Architecture Using MRI. PLoS One (2016) 0.78

4.7-T diffusion tensor imaging of acute traumatic peripheral nerve injury. Neurosurg Focus (2015) 0.78

Neuroinflammatory imaging biomarkers: relevance to multiple sclerosis and its therapy. Neurotherapeutics (2013) 0.78

The impact of human immune deficiency virus and hepatitis C coinfection on white matter microstructural integrity. J Neurovirol (2015) 0.77

Multi-modal imaging of tumor cellularity and Tryptophan metabolism in human Gliomas. Cancer Imaging (2015) 0.77

Robust MR-based approaches to quantifying white matter structure and structure/function alterations in Huntington's disease. J Neurosci Methods (2015) 0.77

Modern Methods for Interrogating the Human Connectome. J Int Neuropsychol Soc (2016) 0.77

Axonal transport rate decreased at the onset of optic neuritis in EAE mice. Neuroimage (2014) 0.77

Diffusion-relaxation correlation spectroscopic imaging: A multidimensional approach for probing microstructure. Magn Reson Med (2017) 0.76

Imaging in sepsis-associated encephalopathy--insights and opportunities. Nat Rev Neurol (2013) 0.76

In vivo mapping of macroscopic neuronal projections in the mouse hippocampus using high-resolution diffusion MRI. Neuroimage (2015) 0.76

In Vivo Evaluation of the Visual Pathway in Streptozotocin-Induced Diabetes by Diffusion Tensor MRI and Contrast Enhanced MRI. PLoS One (2016) 0.76

Diffusion-Weighted Magnetic Resonance Imaging Characterization of White Matter Injury Produced by Axon-Sparing Demyelination and Severe Contusion Spinal Cord Injury in Rats. J Neurotrauma (2016) 0.76

Regional age differences in gray matter diffusivity among healthy older adults. Brain Imaging Behav (2016) 0.76

Neuroimaging biomarkers for epilepsy: advances and relevance to glial cells. Neurochem Int (2013) 0.76

Connectome imaging for mapping human brain pathways. Mol Psychiatry (2017) 0.76

Simulations on the influence of myelin water in diffusion-weighted imaging. Phys Med Biol (2016) 0.75

Greedy Algorithms for Nonnegativity-Constrained Simultaneous Sparse Recovery. Signal Processing (2016) 0.75

Visualization of the medial forebrain bundle using diffusion tensor imaging. Front Neuroanat (2015) 0.75

Correlating Function and Imaging Measures of the Medial Longitudinal Fasciculus. PLoS One (2016) 0.75

The DIAN-TU Next Generation Alzheimer's prevention trial: Adaptive design and disease progression model. Alzheimers Dement (2016) 0.75

Spatiotemporal changes in diffusion, T2 and susceptibility of white matter following mild traumatic brain injury. NMR Biomed (2016) 0.75

Rapid in vivo detection of rat spinal cord injury with double-diffusion-encoded magnetic resonance spectroscopy. Magn Reson Med (2016) 0.75

"A new imaging modality to non-invasively assess multiple sclerosis pathology". J Neuroimmunol (2016) 0.75

Fractional anisotropy to quantify cervical spondylotic myelopathy severity. J Neurosurg Sci (2016) 0.75

Altered contralateral sensorimotor system organization after experimental hemispherectomy: a structural and functional connectivity study. J Cereb Blood Flow Metab (2015) 0.75

In vivo characterization of the connectivity and subcomponents of the human globus pallidus. Neuroimage (2015) 0.75

Diffusion fMRI detects white-matter dysfunction in mice with acute optic neuritis. Neurobiol Dis (2014) 0.75

Diffusivity in multiple sclerosis lesions: At the cutting edge? Neuroimage Clin (2016) 0.75

Diffusion Assessment of Cortical Changes, Induced by Traumatic Spinal Cord Injury. Brain Sci (2017) 0.75

Improved fidelity of brain microstructure mapping from single-shell diffusion MRI. Med Image Anal (2015) 0.75

Empirical Comparison of Diffusion Kurtosis Imaging and Diffusion Basis Spectrum Imaging Using the Same Acquisition in Healthy Young Adults. Front Neurol (2017) 0.75

Diffusion MRI quantifies early axonal loss in the presence of nerve swelling. J Neuroinflammation (2017) 0.75

Separating Blood and Water: Perfusion and Free Water Elimination from Diffusion MRI in the Human Brain. Neuroimage (2017) 0.75

Forebrain knock-out of torsinA reduces striatal free-water and impairs whole-brain functional connectivity in a symptomatic mouse model of DYT1 dystonia. Neurobiol Dis (2017) 0.75

Rotating single-shot acquisition (RoSA) with composite reconstruction for fast high-resolution diffusion imaging. Magn Reson Med (2017) 0.75

Evaluation of structural connectivity changes in betel-quid chewers using generalized q-sampling MRI. Psychopharmacology (Berl) (2017) 0.75

Diffusion Basis Spectral Imaging Detects Ongoing Brain Inflammation in Virologically Well Controlled HIV+ Patients. J Acquir Immune Defic Syndr (2017) 0.75

Articles cited by this

Statistical methods for assessing agreement between two methods of clinical measurement. Lancet (1986) 211.50

Dysmyelination revealed through MRI as increased radial (but unchanged axial) diffusion of water. Neuroimage (2002) 11.37

Mapping complex tissue architecture with diffusion spectrum magnetic resonance imaging. Magn Reson Med (2005) 9.04

Diffusion tensor imaging detects and differentiates axon and myelin degeneration in mouse optic nerve after retinal ischemia. Neuroimage (2003) 8.47

Demyelination increases radial diffusivity in corpus callosum of mouse brain. Neuroimage (2005) 7.24

About "axial" and "radial" diffusivities. Magn Reson Med (2009) 4.13

Measurement of fiber orientation distributions using high angular resolution diffusion imaging. Magn Reson Med (2005) 3.64

The natural history of multiple sclerosis: a geographically based study 10: relapses and long-term disability. Brain (2010) 3.48

The neurotoxicant, cuprizone, as a model to study demyelination and remyelination in the central nervous system. Brain Pathol (2001) 3.47

Toward accurate diagnosis of white matter pathology using diffusion tensor imaging. Magn Reson Med (2007) 3.40

In vivo visualization of myelin water in brain by magnetic resonance. Magn Reson Med (1994) 3.25

Natural history of multiple sclerosis: a unifying concept. Brain (2006) 2.96

Noninvasive detection of cuprizone induced axonal damage and demyelination in the mouse corpus callosum. Magn Reson Med (2006) 2.90

Axial diffusivity is the primary correlate of axonal injury in the experimental autoimmune encephalomyelitis spinal cord: a quantitative pixelwise analysis. J Neurosci (2009) 2.75

Orientationally invariant indices of axon diameter and density from diffusion MRI. Neuroimage (2010) 2.70

Evidence for a two-stage disability progression in multiple sclerosis. Brain (2010) 2.63

Free water elimination and mapping from diffusion MRI. Magn Reson Med (2009) 2.40

An analytical model of restricted diffusion in bovine optic nerve. Magn Reson Med (1997) 2.27

Insights into brain microstructure from the T2 distribution. Magn Reson Imaging (2006) 2.18

Generalized q-sampling imaging. IEEE Trans Med Imaging (2010) 2.10

Effects of cell volume fraction changes on apparent diffusion in human cells. Magn Reson Imaging (2000) 2.06

Multiple-fiber reconstruction algorithms for diffusion MRI. Ann N Y Acad Sci (2005) 2.01

Noninvasive diffusion tensor imaging of evolving white matter pathology in a mouse model of acute spinal cord injury. Magn Reson Med (2007) 1.97

Software for quantification of labeled bacteria from digital microscope images by automated image analysis. Biotechniques (2005) 1.76

Is diffusion anisotropy an accurate monitor of myelination? Correlation of multicomponent T2 relaxation and diffusion tensor anisotropy in human brain. Magn Reson Imaging (2008) 1.70

CXCR2-positive neutrophils are essential for cuprizone-induced demyelination: relevance to multiple sclerosis. Nat Neurosci (2010) 1.65

Axonal loss in multiple sclerosis: a pathological survey of the corticospinal and sensory tracts. Brain (2004) 1.63

Microglial/macrophage accumulation during cuprizone-induced demyelination in C57BL/6 mice. J Neuroimmunol (1998) 1.63

A modified damped Richardson-Lucy algorithm to reduce isotropic background effects in spherical deconvolution. Neuroimage (2009) 1.59

Diffusion basis functions decomposition for estimating white matter intravoxel fiber geometry. IEEE Trans Med Imaging (2007) 1.56

Rostrocaudal analysis of corpus callosum demyelination and axon damage across disease stages refines diffusion tensor imaging correlations with pathological features. J Neuropathol Exp Neurol (2010) 1.50

Pathogenesis of tissue injury in MS lesions. J Neuroimmunol (1999) 1.50

Remyelination protects axons from demyelination-associated axon degeneration. Brain (2008) 1.50

Optimization of diffusion spectrum imaging and q-ball imaging on clinical MRI system. Neuroimage (2008) 1.43

Pluriformity of inflammation in multiple sclerosis shown by ultra-small iron oxide particle enhancement. Brain (2008) 1.38

Peripheral macrophage recruitment in cuprizone-induced CNS demyelination despite an intact blood-brain barrier. J Neuroimmunol (2002) 1.28

On high b diffusion imaging in the human brain: ruminations and experimental insights. Magn Reson Imaging (2009) 1.26

Uniform-penalty inversion of multiexponential decay data. J Magn Reson (1998) 1.25

Increased diffusivity in acute multiple sclerosis lesions predicts risk of black hole. Neurology (2010) 1.24

Recovery from chronic demyelination by thyroid hormone therapy: myelinogenesis induction and assessment by diffusion tensor magnetic resonance imaging. J Neurosci (2008) 1.24

Uniform-penalty inversion of multiexponential decay data. II. Data spacing, T(2) data, systemic data errors, and diagnostics. J Magn Reson (2000) 1.23

Estimation of fiber orientation and spin density distribution by diffusion deconvolution. Neuroimage (2011) 1.21

MRI identification of the rostral-caudal pattern of pathology within the corpus callosum in the cuprizone mouse model. J Magn Reson Imaging (2008) 1.20

Multiple sclerosis: serial study of gadolinium-enhanced MR imaging. Radiology (1988) 1.18

Axonal degeneration and progressive neurologic disability in multiple sclerosis. Neurotox Res (2003) 1.14

The cuprizone model for demyelination. Acta Neurol Scand Suppl (2008) 1.12

Effective medium theory of a diffusion-weighted signal. NMR Biomed (2010) 1.10

In vivo MRI analysis of an inflammatory injury in the developing brain. Brain Behav Immun (2009) 1.00

Estimation of diffusion properties in crossing fiber bundles. IEEE Trans Med Imaging (2010) 0.87

Correlations between the apparent diffusion coefficient, water content, and ultrastructure after induction of vasogenic brain edema in cats. J Neurosurg (1999) 0.87

High resolution reduced-FOV diffusion tensor imaging of the human pons with multi-shot variable density spiral at 3T. Conf Proc IEEE Eng Med Biol Soc (2008) 0.86

Articles by these authors

Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations. N Engl J Med (2012) 13.48

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23

Dysmyelination revealed through MRI as increased radial (but unchanged axial) diffusion of water. Neuroimage (2002) 11.37

Diffusion tensor imaging detects and differentiates axon and myelin degeneration in mouse optic nerve after retinal ischemia. Neuroimage (2003) 8.47

Demyelination increases radial diffusivity in corpus callosum of mouse brain. Neuroimage (2005) 7.24

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat Genet (2009) 7.16

Improved overall survival in melanoma with combined dabrafenib and trametinib. N Engl J Med (2014) 5.65

Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial. Lancet Oncol (2012) 4.19

Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development. Proc Natl Acad Sci U S A (2007) 4.04

A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors. Proc Natl Acad Sci U S A (2003) 3.72

Toward accurate diagnosis of white matter pathology using diffusion tensor imaging. Magn Reson Med (2007) 3.40

Performance of the aspartate aminotransferase-to-platelet ratio index for the staging of hepatitis C-related fibrosis: an updated meta-analysis. Hepatology (2011) 3.38

Mutation of MEF2A in an inherited disorder with features of coronary artery disease. Science (2003) 3.34

Association of alcohol consumption and HIV surrogate markers in participants of the swiss HIV cohort study. J Acquir Immune Defic Syndr (2013) 3.02

Mutations in a human ROBO gene disrupt hindbrain axon pathway crossing and morphogenesis. Science (2004) 3.01

Noninvasive detection of cuprizone induced axonal damage and demyelination in the mouse corpus callosum. Magn Reson Med (2006) 2.90

Identification of an angiogenic factor that when mutated causes susceptibility to Klippel-Trenaunay syndrome. Nature (2004) 2.90

Axial diffusivity is the primary correlate of axonal injury in the experimental autoimmune encephalomyelitis spinal cord: a quantitative pixelwise analysis. J Neurosci (2009) 2.75

Effect of zoledronic acid on disseminated tumour cells in women with locally advanced breast cancer: an open label, randomised, phase 2 trial. Lancet Oncol (2010) 2.74

Adjuvant interferon-based chemoradiation followed by gemcitabine for resected pancreatic adenocarcinoma: a single-institution phase II study. Ann Surg (2008) 2.40

MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells. Biochem Biophys Res Commun (2009) 2.39

A dielectric polymer with high electric energy density and fast discharge speed. Science (2006) 2.30

Remodeling of cardiac fiber structure after infarction in rats quantified with diffusion tensor MRI. Am J Physiol Heart Circ Physiol (2003) 2.30

Detecting axon damage in spinal cord from a mouse model of multiple sclerosis. Neurobiol Dis (2005) 2.25

Relative indices of water diffusion anisotropy are equivalent in live and formalin-fixed mouse brains. Magn Reson Med (2003) 2.17

Mechanisms by which SCN5A mutation N1325S causes cardiac arrhythmias and sudden death in vivo. Cardiovasc Res (2004) 2.04

Tumorigenesis suppressor Pdcd4 down-regulates mitogen-activated protein kinase kinase kinase kinase 1 expression to suppress colon carcinoma cell invasion. Mol Cell Biol (2006) 2.02

Radial diffusivity predicts demyelination in ex vivo multiple sclerosis spinal cords. Neuroimage (2011) 2.02

Towards precise classification of cancers based on robust gene functional expression profiles. BMC Bioinformatics (2005) 2.01

A phase 2 study of high-dose lenalidomide as initial therapy for older patients with acute myeloid leukemia. Blood (2010) 2.01

FtsA forms actin-like protofilaments. EMBO J (2012) 2.00

Image reconstruction from highly undersampled (k, t)-space data with joint partial separability and sparsity constraints. IEEE Trans Med Imaging (2012) 2.00

A randomized controlled evaluation of the effect of community health workers on hospitalization for asthma: the asthma coach. Arch Pediatr Adolesc Med (2009) 1.97

Noninvasive diffusion tensor imaging of evolving white matter pathology in a mouse model of acute spinal cord injury. Magn Reson Med (2007) 1.97

Regional ventricular wall thickening reflects changes in cardiac fiber and sheet structure during contraction: quantification with diffusion tensor MRI. Am J Physiol Heart Circ Physiol (2005) 1.91

Differential sensitivity of in vivo and ex vivo diffusion tensor imaging to evolving optic nerve injury in mice with retinal ischemia. Neuroimage (2006) 1.91

Formalin fixation alters water diffusion coefficient magnitude but not anisotropy in infarcted brain. Magn Reson Med (2005) 1.91

Improved outcomes of pediatric dilated cardiomyopathy with utilization of heart transplantation. J Am Coll Cardiol (2004) 1.89

Blockade of TREM-2 exacerbates experimental autoimmune encephalomyelitis. Eur J Immunol (2007) 1.88

Evolving Wallerian degeneration after transient retinal ischemia in mice characterized by diffusion tensor imaging. Neuroimage (2007) 1.88

Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPARgamma pathway as a therapeutic target in Friedreich's ataxia. Hum Mol Genet (2009) 1.85

Fibroblast growth factor homologous factors control neuronal excitability through modulation of voltage-gated sodium channels. Neuron (2007) 1.84

CXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunity. J Exp Med (2011) 1.82

Regular cellular distribution of plasmids by oscillating and filament-forming ParA ATPase of plasmid pB171. Mol Microbiol (2006) 1.82

Axonal injury detected by in vivo diffusion tensor imaging correlates with neurological disability in a mouse model of multiple sclerosis. NMR Biomed (2008) 1.78

Spinal cord tract diffusion tensor imaging reveals disability substrate in demyelinating disease. Neurology (2013) 1.77

PET-based estradiol challenge as a predictive biomarker of response to endocrine therapy in women with estrogen-receptor-positive breast cancer. Breast Cancer Res Treat (2008) 1.72

Developmental changes in diffusion anisotropy coincide with immature oligodendrocyte progression and maturation of compound action potential. J Neurosci (2005) 1.69

A pilot study of high-throughput, sequence-based mutational profiling of primary human acute myeloid leukemia cell genomes. Proc Natl Acad Sci U S A (2003) 1.69

The Parkinson's disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites. Biochem Biophys Res Commun (2009) 1.67

Surgical resection of the primary tumor is associated with increased long-term survival in patients with stage IV breast cancer after controlling for site of metastasis. Ann Surg Oncol (2007) 1.66

ATPase activity of p97-valosin-containing protein (VCP). D2 mediates the major enzyme activity, and D1 contributes to the heat-induced activity. J Biol Chem (2002) 1.66

Transcription factor MEF2A mutations in patients with coronary artery disease. Hum Mol Genet (2004) 1.65

In vivo magnetomotive optical molecular imaging using targeted magnetic nanoprobes. Proc Natl Acad Sci U S A (2010) 1.65

Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation. J Cell Biol (2009) 1.65

CXCL12 limits inflammation by localizing mononuclear infiltrates to the perivascular space during experimental autoimmune encephalomyelitis. J Immunol (2006) 1.64

PE, a new sulfated saponin from sea cucumber, exhibits anti-angiogenic and anti-tumor activities in vitro and in vivo. Cancer Biol Ther (2005) 1.64

Angiotensin II diminishes the effect of SGK1 on the WNK4-mediated inhibition of ROMK1 channels. Kidney Int (2010) 1.64

Novel CACNA1S mutation causes autosomal dominant hypokalemic periodic paralysis in a Chinese family. J Mol Med (Berl) (2005) 1.63

Anthocyanin prevents CD40-activated proinflammatory signaling in endothelial cells by regulating cholesterol distribution. Arterioscler Thromb Vasc Biol (2006) 1.63

Therapeutic targeting of cancer cell metabolism. J Mol Med (Berl) (2011) 1.62

CXCR4 promotes differentiation of oligodendrocyte progenitors and remyelination. Proc Natl Acad Sci U S A (2010) 1.62

2'-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and -independent mechanisms of host restriction in vivo. PLoS Pathog (2012) 1.62

CXCR3 mediates region-specific antiviral T cell trafficking within the central nervous system during West Nile virus encephalitis. J Immunol (2008) 1.61

CXCR4 antagonism increases T cell trafficking in the central nervous system and improves survival from West Nile virus encephalitis. Proc Natl Acad Sci U S A (2008) 1.60

Anatomically constrained reconstruction from noisy data. Magn Reson Med (2008) 1.60

Gene expression study on peripheral blood identifies progranulin mutations. Ann Neurol (2008) 1.59

Pathological expression of CXCL12 at the blood-brain barrier correlates with severity of multiple sclerosis. Am J Pathol (2008) 1.58

Enhanced sphingosine-1-phosphate receptor 2 expression underlies female CNS autoimmunity susceptibility. J Clin Invest (2014) 1.58

Exclusion of malignancy in thyroid nodules with indeterminate fine-needle aspiration cytology after negative 18F-fluorodeoxyglucose positron emission tomography: interim analysis. World J Surg (2010) 1.57

Complex haplotypes of the PGC-1alpha gene are associated with carbohydrate metabolism and type 2 diabetes. Diabetes (2004) 1.52

Crystal structure of human RANKL complexed with its decoy receptor osteoprotegerin. J Immunol (2012) 1.50

Rostrocaudal analysis of corpus callosum demyelination and axon damage across disease stages refines diffusion tensor imaging correlations with pathological features. J Neuropathol Exp Neurol (2010) 1.50

Plasma S-adenosylhomocysteine is a better biomarker of atherosclerosis than homocysteine in apolipoprotein E-deficient mice fed high dietary methionine. J Nutr (2008) 1.50

Critical role of antigen-specific antibody in experimental autoimmune encephalomyelitis induced by recombinant myelin oligodendrocyte glycoprotein. Eur J Immunol (2002) 1.50

A novel GSK-3 beta-C/EBP alpha-miR-122-insulin-like growth factor 1 receptor regulatory circuitry in human hepatocellular carcinoma. Hepatology (2010) 1.49

Donor CMV serostatus has no impact on CMV viremia or disease when prophylactic granulocyte transfusions are given following allogeneic peripheral blood stem cell transplantation. Blood (2002) 1.48

Tumor necrosis factor alpha protects against lethal West Nile virus infection by promoting trafficking of mononuclear leukocytes into the central nervous system. J Virol (2008) 1.48

Selective sigma-2 ligands preferentially bind to pancreatic adenocarcinomas: applications in diagnostic imaging and therapy. Mol Cancer (2007) 1.46

Prevention of cardiac hypertrophy and heart failure by silencing of NF-kappaB. J Mol Biol (2007) 1.46

Functional analysis of TBX5 missense mutations associated with Holt-Oram syndrome. J Biol Chem (2002) 1.45