Published in Mech Ageing Dev on December 13, 2011
Impaired adaptability of in vivo mitochondrial energetics to acute oxidative insult in aged skeletal muscle. Mech Ageing Dev (2012) 0.99
Caloric restriction and the aging process: a critique. Free Radic Biol Med (2014) 0.97
Involvement of redox state in the aging of Drosophila melanogaster. Antioxid Redox Signal (2013) 0.91
The effects of dietary restriction on oxidative stress in rodents. Free Radic Biol Med (2013) 0.85
Late-onset dietary restriction modulates protein carbonylation and catalase in cerebral hemispheres of aged mice. Cell Mol Neurobiol (2013) 0.79
4-Hydroxy-2(E)-nonenal (HNE) catabolism and formation of HNE adducts are modulated by β oxidation of fatty acids in the isolated rat heart. Free Radic Biol Med (2013) 0.78
Calorie restriction influences key metabolic enzyme activities and markers of oxidative damage in distinct mouse liver mitochondrial sub-populations. Life Sci (2013) 0.78
The effect of calorie restriction on mouse skeletal muscle is sex, strain and time-dependent. Sci Rep (2017) 0.75
Oxidative stress, caloric restriction, and aging. Science (1996) 11.07
Overview of caloric restriction and ageing. Mech Ageing Dev (2005) 6.68
Growth curves and survival characteristics of the animals used in the Biomarkers of Aging Program. J Gerontol A Biol Sci Med Sci (1999) 5.24
Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening. Aging Cell (2009) 3.78
Is the oxidative stress theory of aging dead? Biochim Biophys Acta (2009) 2.86
Mechanisms of aging: an appraisal of the oxidative stress hypothesis. Free Radic Biol Med (2002) 2.55
Genotype and age influence the effect of caloric intake on mortality in mice. FASEB J (2003) 2.51
Influence of diet on survival of mice. Proc Natl Acad Sci U S A (1976) 2.45
Reactive oxygen-mediated protein oxidation in aging and disease. Chem Res Toxicol (1997) 2.27
Role of oxidative stress and protein oxidation in the aging process. Free Radic Biol Med (2002) 2.05
Protein oxidation and proteolysis during aging and oxidative stress. Arch Biochem Biophys (1989) 2.00
Preferential degradation of the oxidatively modified form of glutamine synthetase by intracellular mammalian proteases. J Biol Chem (1985) 1.76
Age-related changes in activities of mitochondrial electron transport complexes in various tissues of the mouse. Arch Biochem Biophys (2000) 1.63
Mitochondrial oxidative damage, hydrogen peroxide release, and aging. Free Radic Biol Med (1994) 1.61
Age-associated decline in mitochondrial respiration and electron transport in Drosophila melanogaster. Biochem J (2005) 1.59
Restriction of energy intake, energy expenditure, and aging. Free Radic Biol Med (2000) 1.51
Reactive Oxygen Species and Aging in Caenorhabditis elegans: Causal or Casual Relationship? Antioxid Redox Signal (2010) 1.48
The role of mitochondrial oxidative stress in aging. Free Radic Biol Med (2003) 1.40
The free-radical damage theory: Accumulating evidence against a simple link of oxidative stress to ageing and lifespan. Bioessays (2011) 1.37
Mitochondrial dysfunction and lipotoxicity. Biochim Biophys Acta (2009) 1.35
The proteasome and its role in the degradation of oxidized proteins. IUBMB Life (2008) 1.32
Caloric restriction prevents age-associated accrual of oxidative damage to mouse skeletal muscle mitochondria. Free Radic Biol Med (1998) 1.32
Measurements of protein carbonyls, ortho- and meta-tyrosine and oxidative phosphorylation complex activity in mitochondria from young and old rats. Free Radic Biol Med (2001) 1.30
The mitochondrial free radical theory of ageing--where do we stand? Front Biosci (2008) 1.29
Lipid oversupply, selective insulin resistance, and lipotoxicity: molecular mechanisms. Biochim Biophys Acta (2009) 1.28
The oxidative stress theory of aging: embattled or invincible? Insights from non-traditional model organisms. Age (Dordr) (2008) 1.20
Oxidized mitochondrial protein degradation and repair in aging and oxidative stress. Antioxid Redox Signal (2010) 1.19
Aging and proteolysis of oxidized proteins. Arch Biochem Biophys (1994) 1.18
Aconitase and ATP synthase are targets of malondialdehyde modification and undergo an age-related decrease in activity in mouse heart mitochondria. Biochem Biophys Res Commun (2005) 1.18
Life span extension in mice by food restriction depends on an energy imbalance. J Nutr (2009) 1.12
Comparison of metabolic rate and oxidative stress between two different strains of mice with varying response to caloric restriction. Exp Gerontol (2008) 1.08
Importance of individuality in oxidative stress and aging. Free Radic Biol Med (2002) 1.06
Relationship of electrophilic stress to aging. Free Radic Biol Med (2011) 1.06
Aging and dietary restriction alter proteasome biogenesis and composition in the brain and liver. Mech Ageing Dev (2009) 0.96
Aging and dietary restriction effects on ubiquitination, sumoylation, and the proteasome in the heart. Mech Ageing Dev (2008) 0.93
Association between life-span extension by caloric restriction and thiol redox state in two different strains of mice. Free Radic Biol Med (2011) 0.88
Effects of aging and dietary restriction on ubiquitination, sumoylation, and the proteasome in the spleen. FEBS Lett (2007) 0.87
Genotype and age influence the effect of caloric intake on mortality in mice. FASEB J (2003) 2.51
Effects of age and caloric restriction on glutathione redox state in mice. Free Radic Biol Med (2003) 1.86
Effect of caloric restriction on life span of the housefly, Musca domestica. FASEB J (2004) 1.80
Locomotor stimulant and discriminative stimulus effects of 'bath salt' cathinones. Behav Pharmacol (2013) 1.60
Age-associated decline in mitochondrial respiration and electron transport in Drosophila melanogaster. Biochem J (2005) 1.59
Mouse heat shock transcription factor 1 deficiency alters cardiac redox homeostasis and increases mitochondrial oxidative damage. EMBO J (2002) 1.58
Effects of overexpression of copper-zinc and manganese superoxide dismutases, catalase, and thioredoxin reductase genes on longevity in Drosophila melanogaster. J Biol Chem (2003) 1.55
Overexpression of glutamate-cysteine ligase extends life span in Drosophila melanogaster. J Biol Chem (2005) 1.37
Free aminothiols, glutathione redox state and protein mixed disulphides in aging Drosophila melanogaster. Biochem J (2004) 1.35
Pro-oxidant shift in glutathione redox state during aging. Adv Drug Deliv Rev (2008) 1.30
Effects of age and caloric intake on glutathione redox state in different brain regions of C57BL/6 and DBA/2 mice. Brain Res (2006) 1.22
Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for cocaine addiction. J Med Chem (2009) 1.22
Ectopic expression of catalase in Drosophila mitochondria increases stress resistance but not longevity. Free Radic Biol Med (2003) 1.20
Aconitase and ATP synthase are targets of malondialdehyde modification and undergo an age-related decrease in activity in mouse heart mitochondria. Biochem Biophys Res Commun (2005) 1.18
A spontaneous point mutation produces monoamine oxidase A/B knock-out mice with greatly elevated monoamines and anxiety-like behavior. J Biol Chem (2004) 1.17
Does overexpression of Cu,Zn-SOD extend life span in Drosophila melanogaster? Exp Gerontol (2003) 1.17
Coenzyme Q, oxidative stress and aging. Mitochondrion (2007) 1.16
Thioredoxin peroxidases can foster cytoprotection or cell death in response to different stressors: over- and under-expression of thioredoxin peroxidase in Drosophila cells. Biochem J (2003) 1.16
Comparison of thiol redox state of mitochondria and homogenates of various tissues between two strains of mice with different longevities. Exp Gerontol (2004) 1.14
Overexpression of glucose-6-phosphate dehydrogenase extends the life span of Drosophila melanogaster. J Biol Chem (2008) 1.12
Resolving mitochondrial protein complexes using nongradient blue native polyacrylamide gel electrophoresis. Anal Biochem (2009) 1.12
Life span extension in mice by food restriction depends on an energy imbalance. J Nutr (2009) 1.12
Peroxiredoxin 5 confers protection against oxidative stress and apoptosis and also promotes longevity in Drosophila. Biochem J (2009) 1.10
Enhanced catabolism of mitochondrial superoxide/hydrogen peroxide and aging in transgenic Drosophila. Biochem J (2005) 1.10
Decreased expression of Cu-Zn superoxide dismutase 1 in ants with extreme lifespan. Proc Natl Acad Sci U S A (2004) 1.10
Concurrent administration of coenzyme Q10 and alpha-tocopherol improves learning in aged mice. Free Radic Biol Med (2005) 1.10
Effects of coenzyme Q(10) administration on its tissue concentrations, mitochondrial oxidant generation, and oxidative stress in the rat. Free Radic Biol Med (2002) 1.10
Effect of coenzyme Q10 intake on endogenous coenzyme Q content, mitochondrial electron transport chain, antioxidative defenses, and life span of mice. Free Radic Biol Med (2005) 1.10
Abuse liability profile of three substituted tryptamines. J Pharmacol Exp Ther (2011) 1.10
Effect of long-term caloric restriction on oxygen consumption and body temperature in two different strains of mice. Mech Ageing Dev (2007) 1.09
Comparison of metabolic rate and oxidative stress between two different strains of mice with varying response to caloric restriction. Exp Gerontol (2008) 1.08
Coenzyme Q intake elevates the mitochondrial and tissue levels of Coenzyme Q and alpha-tocopherol in young mice. J Nutr (2003) 1.07
Temperature-dependent trade-offs between longevity and fertility in the Drosophila mutant, methuselah. Exp Gerontol (2006) 1.06
Nicotine and methamphetamine share discriminative stimulus effects. Drug Alcohol Depend (2007) 1.06
Nitration of tryptophan 372 in succinyl-CoA:3-ketoacid CoA transferase during aging in rat heart mitochondria. Biochemistry (2007) 1.03
Nitrones as neuroprotectants and antiaging drugs. Ann N Y Acad Sci (2002) 1.03
Proteomic identification of specific oxidized proteins in ApoE-knockout mice: relevance to Alzheimer's disease. Free Radic Biol Med (2004) 0.99
Effect of age and caloric restriction on coenzyme Q and alpha-tocopherol levels in the rat. Exp Gerontol (2004) 0.99
Aconitase is the main functional target of aging in the citric acid cycle of kidney mitochondria from mice. Mech Ageing Dev (2005) 0.99
Short-term vitamin E intake fails to improve cognitive or psychomotor performance of aged mice. Free Radic Biol Med (2004) 0.98
Effect of antioxidant-enriched diets on glutathione redox status in tissue homogenates and mitochondria of the senescence-accelerated mouse. Free Radic Biol Med (2005) 0.98
Profiling psychomotor and cognitive aging in four-way cross mice. Age (Dordr) (2006) 0.98
Carbonylation of mitochondrial proteins in Drosophila melanogaster during aging. Biochem Biophys Res Commun (2007) 0.97
Histochemical staining and quantification of dihydrolipoamide dehydrogenase diaphorase activity using blue native PAGE. Electrophoresis (2007) 0.97
Chemical probes for analysis of carbonylated proteins: a review. J Chromatogr B Analyt Technol Biomed Life Sci (2010) 0.97
Carisoprodol-mediated modulation of GABAA receptors: in vitro and in vivo studies. J Pharmacol Exp Ther (2009) 0.96
Mass spectrometry-based survey of age-associated protein carbonylation in rat brain mitochondria. J Mass Spectrom (2007) 0.95
Specificity of age-related carbonylation of plasma proteins in the mouse and rat. Arch Biochem Biophys (2002) 0.94
Δ9-Tetrahydrocannabinol-like discriminative stimulus effects of compounds commonly found in K2/Spice. Behav Pharmacol (2014) 0.94
Social deficits and perseverative behaviors, but not overt aggression, in MAO-A hypomorphic mice. Neuropsychopharmacology (2011) 0.94
Effects of caloric restriction are species-specific. Biogerontology (2006) 0.94
Mechanisms of gamma-glutamylcysteine ligase regulation. Biochim Biophys Acta (2005) 0.94
Comparison of the discriminative stimulus effects of dimethyltryptamine with different classes of psychoactive compounds in rats. Psychopharmacology (Berl) (2009) 0.93
Discriminative and locomotor effects of five synthetic cathinones in rats and mice. Psychopharmacology (Berl) (2014) 0.93
Phenotypic effects of familial amyotrophic lateral sclerosis mutant Sod alleles in transgenic Drosophila. Proc Natl Acad Sci U S A (2002) 0.91
Overexpression of Cu,ZnSOD and MnSOD in transgenic Drosophila. Methods Enzymol (2002) 0.91
Involvement of redox state in the aging of Drosophila melanogaster. Antioxid Redox Signal (2013) 0.91
Spatial learning and psychomotor performance of C57BL/6 mice: age sensitivity and reliability of individual differences. Age (Dordr) (2006) 0.90
Kinetic characteristics of native gamma-glutamylcysteine ligase in the aging housefly, Musca domestica L. Biochem Biophys Res Commun (2005) 0.89
Forebrain-specific expression of monoamine oxidase A reduces neurotransmitter levels, restores the brain structure, and rescues aggressive behavior in monoamine oxidase A-deficient mice. J Biol Chem (2006) 0.89
Effects of superoxide dismutase/catalase mimetics on life span and oxidative stress resistance in the housefly, Musca domestica. Free Radic Biol Med (2002) 0.89
Association between life-span extension by caloric restriction and thiol redox state in two different strains of mice. Free Radic Biol Med (2011) 0.88
The HIV antiretroviral drug efavirenz has LSD-like properties. Neuropsychopharmacology (2013) 0.88
Is serum brain-derived neurotrophic factor related to craving for or use of alcohol, cocaine, or methamphetamine? Neuropsychiatr Dis Treat (2011) 0.88
Cytochrome c oxidase loses catalytic activity and structural integrity during the aging process in Drosophila melanogaster. Biochem Biophys Res Commun (2010) 0.88
Age-associated perturbations in glutathione synthesis in mouse liver. Biochem J (2007) 0.87
Behavioral and neurochemical pharmacology of six psychoactive substituted phenethylamines: mouse locomotion, rat drug discrimination and in vitro receptor and transporter binding and function. Psychopharmacology (Berl) (2013) 0.87
Δ9-Tetrahydrocannabinol-like effects of novel synthetic cannabinoids found on the gray market. Behav Pharmacol (2015) 0.87
Mitochondrial peroxiredoxins are critical for the maintenance of redox state and the survival of adult Drosophila. Free Radic Biol Med (2010) 0.87
Transient focal cerebral ischemia induces long-term cognitive function deficit in an experimental ischemic stroke model. Neurobiol Dis (2013) 0.86
Coenzyme Q(10) supplementation reverses age-related impairments in spatial learning and lowers protein oxidation. Age (Dordr) (2012) 0.86
Changes in dihydrolipoamide dehydrogenase expression and activity during postnatal development and aging in the rat brain. Mech Ageing Dev (2008) 0.86
Expression of multiple copies of mitochondrially targeted catalase or genomic Mn superoxide dismutase transgenes does not extend the life span of Drosophila melanogaster. Free Radic Biol Med (2010) 0.85
Effects of ethanol on cocaine discrimination in rats. Pharmacol Biochem Behav (2003) 0.85
Prolonged intake of coenzyme Q10 impairs cognitive functions in mice. J Nutr (2009) 0.85
Biochemical assay of superoxide dismutase activity in Drosophila. Methods Enzymol (2002) 0.85
In the aging housefly aconitase is the only citric acid cycle enzyme to decline significantly. J Bioenerg Biomembr (2005) 0.84
Reversible inactivation of dihydrolipoamide dehydrogenase by mitochondrial hydrogen peroxide. Free Radic Res (2012) 0.84
Effects of ectopic expression of Drosophila DNA glycosylases dOgg1 and RpS3 in mitochondria. Free Radic Biol Med (2006) 0.84
Detection and characterization of in vivo nitration and oxidation of tryptophan residues in proteins. Methods Enzymol (2008) 0.84