Published in J Infect Dis on December 28, 2011
Impact of Age and Sex on CD4+ Cell Count Trajectories following Treatment Initiation: An Analysis of the Tanzanian HIV Treatment Database. PLoS One (2016) 1.38
Predicting patterns of long-term CD4 reconstitution in HIV-infected children starting antiretroviral therapy in sub-Saharan Africa: a cohort-based modelling study. PLoS Med (2013) 1.19
Pharmacokinetic/pharmacodynamic modelling approaches in paediatric infectious diseases and immunology. Adv Drug Deliv Rev (2014) 0.99
Optimal time for initiating antiretroviral therapy (ART) in HIV-infected, treatment-naive children aged 2 to 5 years old. Cochrane Database Syst Rev (2013) 0.94
The immunological and virological consequences of planned treatment interruptions in children with HIV infection. PLoS One (2013) 0.92
When to start antiretroviral therapy in children aged 2-5 years: a collaborative causal modelling analysis of cohort studies from southern Africa. PLoS Med (2013) 0.89
Higher rates of triple-class virological failure in perinatally HIV-infected teenagers compared with heterosexually infected young adults in Europe. HIV Med (2016) 0.80
Association between age at antiretroviral therapy initiation and 24-month immune response in West-African HIV-infected children. AIDS (2014) 0.80
A mechanistic model for naive CD4 T cell homeostasis in healthy adults and children. Front Immunol (2013) 0.80
Paediatric European Network for Treatment of AIDS Treatment Guideline 2016 update: antiretroviral therapy recommended for all children living with HIV. HIV Med (2016) 0.79
Safety and effectiveness of combination antiretroviral therapy during the first year of treatment in HIV-1 infected Rwandan children: a prospective study. PLoS One (2014) 0.79
Using CD4 percentage and age to optimize pediatric antiretroviral therapy initiation. Pediatrics (2014) 0.79
Incomplete immune reconstitution despite virologic suppression in HIV-1 infected children and adolescents. AIDS (2015) 0.79
Immediate antiretroviral therapy in young HIV-infected children: benefits and risks. Curr Opin HIV AIDS (2014) 0.79
The impact of HIV and antiretroviral therapy on TB risk in children: a systematic review and meta-analysis. Thorax (2017) 0.78
Antiretroviral Therapy in Severely Malnourished, HIV-infected Children in Asia. Pediatr Infect Dis J (2016) 0.78
Cost-effectiveness of early infant HIV diagnosis of HIV-exposed infants and immediate antiretroviral therapy in HIV-infected children under 24 months in Thailand. PLoS One (2014) 0.78
Naive and memory CD4⁺ T cells in HIV eradication and immunization. J Infect Dis (2012) 0.77
Early antiretroviral therapy is protective against epilepsy in children with human immunodeficiency virus infection in botswana. J Acquir Immune Defic Syndr (2015) 0.77
Modelling CD4 T Cell Recovery in Hepatitis C and HIV Co-infected Children Receiving Antiretroviral Therapy. Pediatr Infect Dis J (2017) 0.75
Combined models for pre- and post-treatment longitudinal biomarker data: an application to CD4 counts in HIV-patients. BMC Med Res Methodol (2016) 0.75
Anthropometric Improvement among HIV Infected Pre-School Children Following Initiation of First Line Anti-Retroviral Therapy: Implications for Follow Up. PLoS One (2016) 0.75
Comparing longitudinal CD4 responses to cART among non-perinatally HIV-infected youth versus adults: Results from the HIVRN Cohort. PLoS One (2017) 0.75
Differences in virologic and immunologic response to antiretroviral therapy among HIV-1-infected infants and children. AIDS (2016) 0.75
Clinical, Virologic, Immunologic Outcomes and Emerging HIV Drug Resistance Patterns in Children and Adolescents in Public ART Care in Zimbabwe. PLoS One (2015) 0.75
Hepatitis C Co-Infection and CD4+ T Cell Recovery in HIV-Infected Children Receiving Anti-Retroviral Therapy. Pediatr Infect Dis J (2016) 0.75
Thymic Output and CD4 T-Cell Reconstitution in HIV-Infected Children on Early and Interrupted Antiretroviral Treatment: Evidence from the Children with HIV Early Antiretroviral Therapy Trial. Front Immunol (2017) 0.75
Predicting CD4 T-cell reconstitution following paediatric haematopoietic stem cell transplantation. Clin Pharmacol Ther (2017) 0.75
Early antiretroviral therapy and mortality among HIV-infected infants. N Engl J Med (2008) 17.12
Mortality after fluid bolus in African children with severe infection. N Engl J Med (2011) 10.99
Whole-genome sequencing to delineate Mycobacterium tuberculosis outbreaks: a retrospective observational study. Lancet Infect Dis (2012) 7.18
Multilocus sequence typing of Clostridium difficile. J Clin Microbiol (2009) 4.16
A pilot study of rapid benchtop sequencing of Staphylococcus aureus and Clostridium difficile for outbreak detection and surveillance. BMJ Open (2012) 3.93
Determinants of survival following HIV-1 seroconversion after the introduction of HAART. Lancet (2003) 3.84
Predictors of trend in CD4-positive T-cell count and mortality among HIV-1-infected individuals with virological failure to all three antiretroviral-drug classes. Lancet (2004) 3.59
Effect of transmitted drug resistance on virological and immunological response to initial combination antiretroviral therapy for HIV (EuroCoord-CHAIN joint project): a European multicohort study. Lancet Infect Dis (2011) 3.59
Whole-genome sequencing shows that patient-to-patient transmission rarely accounts for acquisition of Staphylococcus aureus in an intensive care unit. Clin Infect Dis (2013) 3.05
First-line antiretroviral therapy with a protease inhibitor versus non-nucleoside reverse transcriptase inhibitor and switch at higher versus low viral load in HIV-infected children: an open-label, randomised phase 2/3 trial. Lancet Infect Dis (2011) 3.04
Undiagnosed HIV infection among adolescents seeking primary health care in Zimbabwe. Clin Infect Dis (2010) 2.74
Combining electronic healthcare databases in Europe to allow for large-scale drug safety monitoring: the EU-ADR Project. Pharmacoepidemiol Drug Saf (2010) 2.57
Virologic, immunologic, and clinical benefits from early combined antiretroviral therapy in infants with perinatal HIV-1 infection. AIDS (2006) 2.26
PENTA 2009 guidelines for the use of antiretroviral therapy in paediatric HIV-1 infection. HIV Med (2009) 2.16
Clinical Clostridium difficile: clonality and pathogenicity locus diversity. PLoS One (2011) 2.04
Microevolutionary analysis of Clostridium difficile genomes to investigate transmission. Genome Biol (2012) 2.04
Prevalence, incidence and predictors of severe anaemia with zidovudine-containing regimens in African adults with HIV infection within the DART trial. Antivir Ther (2006) 2.02
WHO guidelines on fluid resuscitation in children: missing the FEAST data. BMJ (2014) 2.00
Assessment of second-line antiretroviral regimens for HIV therapy in Africa. N Engl J Med (2014) 2.00
Multicenter prospective study of the burden of rotavirus acute gastroenteritis in Europe, 2004-2005: the REVEAL study. J Infect Dis (2007) 1.99
Severe renal dysfunction and risk factors associated with renal impairment in HIV-infected adults in Africa initiating antiretroviral therapy. Clin Infect Dis (2008) 1.98
Drug use in children: cohort study in three European countries. BMJ (2008) 1.91
Risk of triple-class virological failure in children with HIV: a retrospective cohort study. Lancet (2011) 1.90
Causes of acute hospitalization in adolescence: burden and spectrum of HIV-related morbidity in a country with an early-onset and severe HIV epidemic: a prospective survey. PLoS Med (2010) 1.89
The cost-effectiveness of cotrimoxazole prophylaxis in HIV-infected children in Zambia. AIDS (2008) 1.81
Quantifying the development of the peripheral naive CD4+ T-cell pool in humans. Blood (2009) 1.79
Ranked prediction of p53 targets using hidden variable dynamic modeling. Genome Biol (2006) 1.78
Differences in factors associated with initial growth, CD4, and viral load responses to ART in HIV-infected children in Kampala, Uganda, and the United Kingdom/Ireland. J Acquir Immune Defic Syndr (2008) 1.75
Time trends in drug resistant HIV-1 infections in the United Kingdom up to 2009: multicentre observational study. BMJ (2012) 1.71
Early postoperative monocyte deactivation predicts systemic inflammation and prolonged stay in pediatric cardiac intensive care. Crit Care Med (2002) 1.68
Response to highly active antiretroviral therapy varies with age: the UK and Ireland Collaborative HIV Paediatric Study. AIDS (2004) 1.67
Determinants of survival without antiretroviral therapy after infancy in HIV-1-infected Zambian children in the CHAP Trial. J Acquir Immune Defic Syndr (2006) 1.62
The impact of daily cotrimoxazole prophylaxis and antiretroviral therapy on mortality and hospital admissions in HIV-infected Zambian children. Clin Infect Dis (2007) 1.61
Early antiretroviral therapy improves neurodevelopmental outcomes in infants. AIDS (2012) 1.59
Clostridium difficile mixed infection and reinfection. J Clin Microbiol (2011) 1.59
Exploring mechanisms of excess mortality with early fluid resuscitation: insights from the FEAST trial. BMC Med (2013) 1.57
Impact of human immunodeficiency virus type 1 subtypes on virologic response and emergence of drug resistance among children in the Paediatric European Network for Treatment of AIDS (PENTA) 5 trial. J Infect Dis (2002) 1.56
Incidence of mucocutaneous reactions in children treated with niflumic acid, other nonsteroidal antiinflammatory drugs, or nonopioid analgesics. Pediatrics (2005) 1.55
Increasing antiretroviral drug access for children with HIV infection. Pediatrics (2007) 1.54
Early structural and functional changes of the vasculature in HIV-infected children: impact of disease and antiretroviral therapy. Circulation (2005) 1.54
Nosocomial rotavirus infection in European countries: a review of the epidemiology, severity and economic burden of hospital-acquired rotavirus disease. Pediatr Infect Dis J (2006) 1.54
Predictors of first recurrence of Clostridium difficile infection: implications for initial management. Clin Infect Dis (2012) 1.51
Effect of early antiretroviral therapy on the risk of AIDS/death in HIV-infected infants. AIDS (2009) 1.49
Pregnancy and infant outcomes among HIV-infected women taking long-term ART with and without tenofovir in the DART trial. PLoS Med (2012) 1.44
Distinct functional significance of Akt and mTOR constitutive activation in mantle cell lymphoma. Blood (2008) 1.43
Excellent adherence to antiretrovirals in HIV+ Zambian children is compromised by disrupted routine, HIV nondisclosure, and paradoxical income effects. PLoS One (2011) 1.43
Effects of nutritional rehabilitation on intestinal function and on CD4 cell number in children with HIV. J Pediatr Gastroenterol Nutr (2002) 1.43
Intussusception among young children in Europe. Pediatr Infect Dis J (2006) 1.42
Transcriptional instability during evolving sepsis may limit biomarker based risk stratification. PLoS One (2013) 1.41
Effect of cotrimoxazole on causes of death, hospital admissions and antibiotic use in HIV-infected children. AIDS (2007) 1.41
Clinical manifestations and socio-economic impact of influenza among healthy children in the community. J Infect (2011) 1.40
Disruption of the stratum corneum allows potent epicutaneous immunization with protein antigens resulting in a dominant systemic Th2 response. Eur J Immunol (2004) 1.40
Fidaxomicin versus vancomycin for Clostridium difficile infection: meta-analysis of pivotal randomized controlled trials. Clin Infect Dis (2012) 1.39
Detection of mixed infection from bacterial whole genome sequence data allows assessment of its role in Clostridium difficile transmission. PLoS Comput Biol (2013) 1.38
Nevirapine concentrations in HIV-infected children treated with divided fixed-dose combination antiretroviral tablets in Malawi and Zambia. Antivir Ther (2007) 1.38
Patterns of individual and population-level adherence to antiretroviral therapy and risk factors for poor adherence in the first year of the DART trial in Uganda and Zimbabwe. J Acquir Immune Defic Syndr (2008) 1.37
Nevirapine, stavudine and lamivudine pharmacokinetics in African children on paediatric fixed-dose combination tablets. AIDS (2008) 1.36
Viral rebound and emergence of drug resistance in the absence of viral load testing: a randomized comparison between zidovudine-lamivudine plus Nevirapine and zidovudine-lamivudine plus Abacavir. J Infect Dis (2010) 1.36
Cost effectiveness analysis of clinically driven versus routine laboratory monitoring of antiretroviral therapy in Uganda and Zimbabwe. PLoS One (2012) 1.33
Outcomes for human immunodeficiency virus-1-infected infants in the United kingdom and Republic of Ireland in the era of effective antiretroviral therapy. Pediatr Infect Dis J (2006) 1.33
Treatment of young children with HIV infection: using evidence to inform policymakers. PLoS Med (2012) 1.32
Decreased TNF-alpha synthesis by macrophages restricts cutaneous immunosurveillance by memory CD4+ T cells during aging. J Exp Med (2009) 1.29
Changing patterns of clinical events in perinatally HIV-1-infected children during the era of HAART. AIDS (2007) 1.28
Nevirapine clearance from plasma in African adults stopping therapy: a pharmacokinetic substudy. AIDS (2007) 1.26
A novel form of integrin dysfunction involving beta1, beta2, and beta3 integrins. J Clin Invest (2003) 1.24
Risk factors for Clostridium difficile acquisition in infants: importance of study design. Clin Infect Dis (2013) 1.24
Impact of community-acquired paediatric rotavirus gastroenteritis on family life: data from the REVEAL study. BMC Fam Pract (2010) 1.24
Risk and protective factors for meningococcal disease in adolescents: matched cohort study. BMJ (2006) 1.21
Long-term clinical outcome of AIDS-related Kaposi's sarcoma during highly active antiretroviral therapy. Int J Oncol (2005) 1.21
Recombinational switching of the Clostridium difficile S-layer and a novel glycosylation gene cluster revealed by large-scale whole-genome sequencing. J Infect Dis (2012) 1.21
Quantifying thymic export: combining models of naive T cell proliferation and TCR excision circle dynamics gives an explicit measure of thymic output. J Immunol (2009) 1.20
Estimating glomerular filtration rate in HIV-infected adults in Africa: comparison of Cockcroft-Gault and Modification of Diet in Renal Disease formulae. Antivir Ther (2008) 1.20
Predicting patterns of long-term CD4 reconstitution in HIV-infected children starting antiretroviral therapy in sub-Saharan Africa: a cohort-based modelling study. PLoS Med (2013) 1.19