PubRank

Paul S Freemont

Author PubWeight™ 46.73‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disorders. Nat Genet 2003 1.99
2 The crystal structure of murine p97/VCP at 3.6A. J Struct Biol 2003 1.98
3 Promyelocytic leukemia nuclear bodies associate with transcriptionally active genomic regions. J Cell Biol 2004 1.74
4 Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47. EMBO J 2004 1.68
5 The Salmonella kinase SteC targets the MAP kinase MEK to regulate the host actin cytoskeleton. Cell Host Microbe 2012 1.66
6 Insights into adaptor binding to the AAA protein p97. Biochem Soc Trans 2008 1.66
7 Going through the motions: the ATPase cycle of p97. J Struct Biol 2006 1.61
8 Human PLU-1 Has transcriptional repression properties and interacts with the developmental transcription factors BF-1 and PAX9. J Biol Chem 2003 1.50
9 Conformational changes in the AAA ATPase p97-p47 adaptor complex. EMBO J 2006 1.48
10 Motions and negative cooperativity between p97 domains revealed by cryo-electron microscopy and quantised elastic deformational model. J Mol Biol 2003 1.36
11 Different quaternary structures of human RECQ1 are associated with its dual enzymatic activity. PLoS Biol 2007 1.36
12 Analysis of nucleotide binding to P97 reveals the properties of a tandem AAA hexameric ATPase. J Biol Chem 2008 1.36
13 The role of the N-domain in the ATPase activity of the mammalian AAA ATPase p97/VCP. J Biol Chem 2012 1.32
14 Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS. Proc Natl Acad Sci U S A 2009 1.30
15 Structural insights into the p97-Ufd1-Npl4 complex. Proc Natl Acad Sci U S A 2007 1.22
16 Regulation of p97 in the ubiquitin-proteasome system by the UBX protein-family. Biochim Biophys Acta 2011 1.11
17 One-pot DNA construction for synthetic biology: the Modular Overlap-Directed Assembly with Linkers (MODAL) strategy. Nucleic Acids Res 2013 1.03
18 Validation of an entirely in vitro approach for rapid prototyping of DNA regulatory elements for synthetic biology. Nucleic Acids Res 2013 1.00
19 Computational design approaches and tools for synthetic biology. Integr Biol (Camb) 2011 0.99
20 Detailed structural insights into the p97-Npl4-Ufd1 interface. J Biol Chem 2007 0.99
21 Machinery of protein folding and unfolding. Curr Opin Struct Biol 2002 0.98
22 The transcriptional regulator CBP has defined spatial associations within interphase nuclei. PLoS Comput Biol 2006 0.97
23 Distinct conformations of the protein complex p97-Ufd1-Npl4 revealed by electron cryomicroscopy. Proc Natl Acad Sci U S A 2012 0.97
24 Opportunities for microfluidic technologies in synthetic biology. J R Soc Interface 2009 0.97
25 Segmentation of fluorescence microscopy images for quantitative analysis of cell nuclear architecture. Biophys J 2009 0.94
26 Cd36, a class B scavenger receptor, functions as a monomer to bind acetylated and oxidized low-density lipoproteins. Protein Sci 2007 0.94
27 Structural and functional implications of phosphorylation and acetylation in the regulation of the AAA+ protein p97. Biochem Cell Biol 2010 0.92
28 Quantitative analysis of cell nucleus organisation. PLoS Comput Biol 2007 0.88
29 The p97-FAF1 protein complex reveals a common mode of p97 adaptor binding. J Biol Chem 2014 0.87
30 Analysis of spatial point patterns in nuclear biology. PLoS One 2012 0.85
31 R2oDNA designer: computational design of biologically neutral synthetic DNA sequences. ACS Synth Biol 2014 0.85
32 Inter-ring rotations of AAA ATPase p97 revealed by electron cryomicroscopy. Open Biol 2014 0.84
33 Specialization of an Exonuclease III family enzyme in the repair of 3' DNA lesions during base excision repair in the human pathogen Neisseria meningitidis. Nucleic Acids Res 2011 0.83
34 Validating a Coarse-Grained Potential Energy Function through Protein Loop Modelling. PLoS One 2013 0.82
35 Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis. Proc Natl Acad Sci U S A 2012 0.80
36 A novel pyrazolo[1,5-a]pyrimidine is a potent inhibitor of cyclin-dependent protein kinases 1, 2, and 9, which demonstrates antitumor effects in human tumor xenografts following oral administration. J Med Chem 2010 0.79
37 SUMO. Curr Biol 2003 0.78
38 Complete backbone resonance assignments of p47: the 41kDa adaptor protein of the AAA ATPase p97. J Biomol NMR 2004 0.78
39 PML nuclear bodies and other TRIM-defined subcellular compartments. Adv Exp Med Biol 2012 0.78
40 Multilevel Regulation and Translational Switches in Synthetic Biology. IEEE Trans Biomed Circuits Syst 2015 0.77
41 Design of a prototype flow microreactor for synthetic biology in vitro. Lab Chip 2013 0.76
42 AAA proteins and the life process. Biochem Soc Trans 2008 0.75