Published in BMB Rep on January 01, 2012
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Human RNAi pathway: crosstalk with organelles and cells. Funct Integr Genomics (2013) 0.77
H2O2-Activated Mitochondrial Phospholipase iPLA2γ Prevents Lipotoxic Oxidative Stress in Synergy with UCP2, Amplifies Signaling via G-Protein-Coupled Receptor GPR40, and Regulates Insulin Secretion in Pancreatic β-Cells. Antioxid Redox Signal (2015) 0.76
Mouse Tafazzin Is Required for Male Germ Cell Meiosis and Spermatogenesis. PLoS One (2015) 0.75
Phospholipids in mitochondrial dysfunction during hemorrhagic shock. J Bioenerg Biomembr (2016) 0.75
Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. Cell (2007) 18.35
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. EMBO J (2008) 12.89
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Mitochondria: dynamic organelles in disease, aging, and development. Cell (2006) 8.30
MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline. Dev Cell (2007) 7.66
Specialized piRNA pathways act in germline and somatic tissues of the Drosophila ovary. Cell (2009) 6.39
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Structural basis of mitochondrial tethering by mitofusin complexes. Science (2004) 4.21
A regulatory circuit for piwi by the large Maf gene traffic jam in Drosophila. Nature (2009) 3.68
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A common lipid links Mfn-mediated mitochondrial fusion and SNARE-regulated exocytosis. Nat Cell Biol (2006) 3.56
Unique germ-line organelle, nuage, functions to repress selfish genetic elements in Drosophila melanogaster. Proc Natl Acad Sci U S A (2007) 3.31
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Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization. Curr Biol (1997) 3.22
Human ADP-ribosylation factor-activated phosphatidylcholine-specific phospholipase D defines a new and highly conserved gene family. J Biol Chem (1995) 3.10
The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline. Dev Cell (2009) 2.96
piRNA-associated germline nuage formation and spermatogenesis require MitoPLD profusogenic mitochondrial-surface lipid signaling. Dev Cell (2011) 2.73
Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness. Nat Chem Biol (2009) 2.72
Phospholipase D: a lipid centric review. Cell Mol Life Sci (2005) 2.57
An in vivo RNAi assay identifies major genetic and cellular requirements for primary piRNA biogenesis in Drosophila. EMBO J (2010) 2.51
Mutagenesis of phospholipase D defines a superfamily including a trans-Golgi viral protein required for poxvirus pathogenicity. EMBO J (1997) 2.49
Apoptotic force and tissue dynamics during Drosophila embryogenesis. Science (2008) 2.33
Roles for the Yb body components Armitage and Yb in primary piRNA biogenesis in Drosophila. Genes Dev (2010) 2.33
5-Fluoro-2-indolyl des-chlorohalopemide (FIPI), a phospholipase D pharmacological inhibitor that alters cell spreading and inhibits chemotaxis. Mol Pharmacol (2008) 2.24
Sequential regulation of DOCK2 dynamics by two phospholipids during neutrophil chemotaxis. Science (2009) 2.23
Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus. Science (2011) 2.17
Cytoplasmic compartmentalization of the fetal piRNA pathway in mice. PLoS Genet (2009) 2.11
Tdrd1/Mtr-1, a tudor-related gene, is essential for male germ-cell differentiation and nuage/germinal granule formation in mice. Proc Natl Acad Sci U S A (2006) 2.09
MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline. Dev Cell (2011) 1.94
The fatty liver dystrophy (fld) mutation. A new mutant mouse with a developmental abnormality in triglyceride metabolism and associated tissue-specific defects in lipoprotein lipase and hepatic lipase activities. J Biol Chem (1989) 1.91
MVH in piRNA processing and gene silencing of retrotransposons. Genes Dev (2010) 1.84
GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet (2009) 1.83
Crystal structure of a phospholipase D family member. Nat Struct Biol (1999) 1.83
piRNA-mediated nuclear accumulation of retrotransposon transcripts in the Drosophila female germline. Proc Natl Acad Sci U S A (2008) 1.79
Physiological functions of mitochondrial fusion. Ann N Y Acad Sci (2010) 1.66
MOV10L1 is necessary for protection of spermatocytes against retrotransposons by Piwi-interacting RNAs. Proc Natl Acad Sci U S A (2010) 1.66
The phospholipase D1 pathway modulates macroautophagy. Nat Commun (2010) 1.56
Cardiolipin deficiency releases cytochrome c from the inner mitochondrial membrane and accelerates stimuli-elicited apoptosis. Cell Death Differ (2006) 1.55
Characterization of the peripheral neuropathy in neonatal and adult mice that are homozygous for the fatty liver dystrophy (fld) mutation. J Biol Chem (1991) 1.39
Phosphatidate degradation: phosphatidate phosphatases (lipins) and lipid phosphate phosphatases. Biochim Biophys Acta (2009) 1.38
Small RNAs in early mammalian development: from gametes to gastrulation. Development (2011) 1.33
The Yb protein defines a novel organelle and regulates male germline stem cell self-renewal in Drosophila melanogaster. J Cell Biol (2009) 1.26
Phospholipase D2-dependent inhibition of the nuclear hormone receptor PPARgamma by cyclic phosphatidic acid. Mol Cell (2010) 1.23
The potential for phospholipase D as a new therapeutic target. Expert Opin Ther Targets (2007) 1.23
Phospholipid signalling through phospholipase D and phosphatidic acid. IUBMB Life (2006) 1.18
Targeting phospholipase D with small-molecule inhibitors as a potential therapeutic approach for cancer metastasis. Future Oncol (2009) 1.17
Telomeric transgenes and trans-silencing in Drosophila. Genetica (2003) 1.12
Mitochondria and the culture of the Borg: understanding the integration of mitochondrial function within the reticulum, the cell, and the organism. Bioessays (2010) 1.12
Spatial, temporal and molecular hierarchies in the link between death, delamination and dorsal closure. Development (2011) 1.09
Lipid signaling on the mitochondrial surface. Biochim Biophys Acta (2009) 0.98
Telomeric trans-silencing in Drosophila melanogaster: tissue specificity, development and functional interactions between non-homologous telomeres. PLoS One (2008) 0.92
Phospholipase D mechanism using Streptomyces PLD. Biochim Biophys Acta (2009) 0.88
A descent into the nuage: the maelstrom of transposon control. Dev Cell (2008) 0.86
Mitochondria as integrators of signal transduction and energy production in cardiac physiology and disease. J Mol Med (Berl) (2010) 0.81
piRNAs meet mitochondria. Dev Cell (2011) 0.80
Phospholipase D2-generated phosphatidic acid couples EGFR stimulation to Ras activation by Sos. Nat Cell Biol (2007) 3.68
A common lipid links Mfn-mediated mitochondrial fusion and SNARE-regulated exocytosis. Nat Cell Biol (2006) 3.56
piRNA-associated germline nuage formation and spermatogenesis require MitoPLD profusogenic mitochondrial-surface lipid signaling. Dev Cell (2011) 2.73
5-Fluoro-2-indolyl des-chlorohalopemide (FIPI), a phospholipase D pharmacological inhibitor that alters cell spreading and inhibits chemotaxis. Mol Pharmacol (2008) 2.24
Sequential regulation of DOCK2 dynamics by two phospholipids during neutrophil chemotaxis. Science (2009) 2.23
Phospholipase D2 localizes to the plasma membrane and regulates angiotensin II receptor endocytosis. Mol Biol Cell (2004) 1.93
Key roles for the lipid signaling enzyme phospholipase d1 in the tumor microenvironment during tumor angiogenesis and metastasis. Sci Signal (2012) 1.86
3' end cDNA amplification using classic RACE. Nat Protoc (2006) 1.85
5' end cDNA amplification using classic RACE. Nat Protoc (2006) 1.77
Krüppel-like factor 6 regulates mitochondrial function in the kidney. J Clin Invest (2015) 1.72
IMGT/HighV QUEST paradigm for T cell receptor IMGT clonotype diversity and next generation repertoire immunoprofiling. Nat Commun (2013) 1.71
Phospholipase D1 production of phosphatidic acid at the plasma membrane promotes exocytosis of large dense-core granules at a late stage. J Biol Chem (2007) 1.69
PLD1 and ERK2 regulate cytosolic lipid droplet formation. J Cell Sci (2006) 1.67
PLD1 regulates mTOR signaling and mediates Cdc42 activation of S6K1. Curr Biol (2003) 1.62
Cytosolic lipid droplets increase in size by microtubule-dependent complex formation. Arterioscler Thromb Vasc Biol (2005) 1.62
The phospholipase D1 pathway modulates macroautophagy. Nat Commun (2010) 1.56
Insulin-stimulated plasma membrane fusion of Glut4 glucose transporter-containing vesicles is regulated by phospholipase D1. Mol Biol Cell (2005) 1.53
Asymmetric phospholipid distribution drives in vitro reconstituted SNARE-dependent membrane fusion. Proc Natl Acad Sci U S A (2006) 1.51
A role for phosphatidic acid in COPI vesicle fission yields insights into Golgi maintenance. Nat Cell Biol (2008) 1.50
Impaired alpha(IIb)beta(3) integrin activation and shear-dependent thrombus formation in mice lacking phospholipase D1. Sci Signal (2010) 1.49
Regulation of phospholipase D1 subcellular cycling through coordination of multiple membrane association motifs. J Cell Biol (2003) 1.47
Design of expression vectors for RNA interference based on miRNAs and RNA splicing. FEBS J (2006) 1.37
Calcium-regulated exocytosis of dense-core vesicles requires the activation of ADP-ribosylation factor (ARF)6 by ARF nucleotide binding site opener at the plasma membrane. J Cell Biol (2002) 1.33
Isolation of circulating epithelial and tumor progenitor cells with an invasive phenotype from breast cancer patients. Int J Cancer (2010) 1.31
Class III PI-3-kinase activates phospholipase D in an amino acid-sensing mTORC1 pathway. J Cell Biol (2011) 1.31
Phospholipases D1 and D2 regulate different phases of exocytosis in mast cells. J Immunol (2002) 1.27
Phospholipase D2-dependent inhibition of the nuclear hormone receptor PPARgamma by cyclic phosphatidic acid. Mol Cell (2010) 1.23
The potential for phospholipase D as a new therapeutic target. Expert Opin Ther Targets (2007) 1.23
Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I {alpha}. J Exp Med (2005) 1.22
Dynamics and function of phospholipase D and phosphatidic acid during phagocytosis. Traffic (2006) 1.19
Targeting phospholipase D with small-molecule inhibitors as a potential therapeutic approach for cancer metastasis. Future Oncol (2009) 1.17
Crucial role of the small GTPase ARF6 in hepatic cord formation during liver development. Mol Cell Biol (2006) 1.12
A lipid-signaled myosin phosphatase surge disperses cortical contractile force early in cell spreading. Mol Biol Cell (2008) 1.07
A phosphatidic acid binding/nuclear localization motif determines lipin1 function in lipid metabolism and adipogenesis. Mol Biol Cell (2010) 1.07
Phospholipase D2 functions as a downstream signaling molecule of MAP kinase pathway in L1-stimulated neurite outgrowth of cerebellar granule neurons. J Neurochem (2004) 1.06
Phosphatidic acid (PA)-preferring phospholipase A1 regulates mitochondrial dynamics. J Biol Chem (2014) 1.05
Role of activation of PIP5Kgamma661 by AP-2 complex in synaptic vesicle endocytosis. EMBO J (2007) 1.05
Phospholipase D1 regulates secretagogue-stimulated insulin release in pancreatic beta-cells. J Biol Chem (2004) 1.05
A novel cell-free mitochondrial fusion assay amenable for high-throughput screenings of fusion modulators. BMC Biol (2010) 1.04
Phosphatidylinositol 4-phosphate 5-kinase is essential for ROCK-mediated neurite remodeling. J Biol Chem (2002) 1.04
Phosphatidic acid is a leukocyte chemoattractant that acts through S6 kinase signaling. J Biol Chem (2010) 1.00
Lipid signaling on the mitochondrial surface. Biochim Biophys Acta (2009) 0.98
Amplification of 5' end cDNA with 'new RACE'. Nat Protoc (2006) 0.97
A role for phospholipase D3 in myotube formation. PLoS One (2012) 0.97
Dependence of phospholipase D1 multi-monoubiquitination on its enzymatic activity and palmitoylation. J Biol Chem (2010) 0.97
Heterogeneity of phosphatidic acid levels and distribution at the plasma membrane in living cells as visualized by a Föster resonance energy transfer (FRET) biosensor. J Biol Chem (2010) 0.93
Deficiencies of the lipid-signaling enzymes phospholipase D1 and D2 alter cytoskeletal organization, macrophage phagocytosis, and cytokine-stimulated neutrophil recruitment. PLoS One (2013) 0.92
Rapid amplification of cDNA ends (RACE). Methods Mol Biol (2011) 0.92
G-protein-coupled receptor regulation of phospholipase D. Methods Enzymol (2002) 0.91
Phosphatidylethanol accumulation promotes intestinal hyperplasia by inducing ZONAB-mediated cell density increase in response to chronic ethanol exposure. Mol Cancer Res (2007) 0.90
A role for Phospholipase D in Drosophila embryonic cellularization. BMC Dev Biol (2006) 0.90
Peroxiredoxin II functions as a signal terminator for H2O2-activated phospholipase D1. FEBS J (2005) 0.90
A quantitative assay for mitochondrial fusion using Renilla luciferase complementation. Mitochondrion (2010) 0.90
Regulation of phototransduction responsiveness and retinal degeneration by a phospholipase D-generated signaling lipid. J Cell Biol (2005) 0.90
Phospholipase D1-promoted release of tissue plasminogen activator facilitates neurite outgrowth. J Neurosci (2005) 0.89
Basis for the isoform-specific interaction of myosin phosphatase subunits protein phosphatase 1c beta and myosin phosphatase targeting subunit 1. J Biol Chem (2009) 0.88
Essential role for phospholipase D2 activation downstream of ERK MAP kinase in nerve growth factor-stimulated neurite outgrowth from PC12 cells. J Biol Chem (2004) 0.88
Mitochondria: signaling with phosphatidic acid. Int J Biochem Cell Biol (2012) 0.87
Reversible bleb formation in mast cells stimulated with antigen is Ca2+/calmodulin-dependent and bleb size is regulated by ARF6. Biochem J (2009) 0.87
Ca(2+)- and phospholipase D-dependent and -independent pathways activate mTOR signaling. FEBS Lett (2003) 0.87
Increased expression of two phospholipase D isoforms during experimentally induced hippocampal mossy fiber outgrowth. Glia (2004) 0.86
Pharmacological inhibition of phospholipase D protects mice from occlusive thrombus formation and ischemic stroke--brief report. Arterioscler Thromb Vasc Biol (2013) 0.83
Phospholipase D2 mediates acute aldosterone secretion in response to angiotensin II in adrenal glomerulosa cells. Endocrinology (2010) 0.82
Calphostin-C induction of vascular smooth muscle cell apoptosis proceeds through phospholipase D and microtubule inhibition. J Biol Chem (2003) 0.82
Regulation of mitochondrial morphology by lipids. Biofactors (2014) 0.79
Phosphatidylinositol-4-phosphate-5-kinase alpha deficiency alters dynamics of glucose-stimulated insulin release to improve glucohomeostasis and decrease obesity in mice. Diabetes (2011) 0.79
Synergism between phospholipase D2 and sorbitol accumulation in diabetic cataract formation through modulation of Na,K-ATPase activity and osmotic stress. Exp Eye Res (2006) 0.78
Visualizing mitochondrial lipids and fusion events in Mammalian cells. Methods Cell Biol (2012) 0.78
Phospholipase D activity underlies very-low-density lipoprotein (VLDL)-induced aldosterone production in adrenal glomerulosa cells. Endocrinology (2014) 0.78
Parathyroid hormone stimulates phosphatidylethanolamine hydrolysis by phospholipase D in osteoblastic cells. Lipids (2005) 0.77
Regulation of phosphatidylinositol 4-phosphate 5-kinase activity by partner proteins. Methods Enzymol (2007) 0.76
Cardiolipin synthesis is required to support human cholesterol biosynthesis from palmitate upon serum removal in Hela cells. Can J Physiol Pharmacol (2009) 0.75
5'-End cDNA Amplification Using Classic RACE. CSH Protoc (2006) 0.75
Monitoring insulin-stimulated production of signaling lipids at the plasma membrane. Methods Mol Biol (2009) 0.75
3'-End cDNA Amplification Using Classic RACE. CSH Protoc (2006) 0.75
5'-End cDNA Amplification Using New RACE. CSH Protoc (2006) 0.75
Cap-Switching RACE. CSH Protoc (2006) 0.75
Identification of alternative transcripts using rapid amplification of cDNA ends (RACE). Methods Mol Biol (2009) 0.75
The role of phospholipase D in Glut-4 translocation. Diabetes Metab Res Rev (2003) 0.75