Published in Tissue Eng Part C Methods on March 19, 2012
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Controlled aggregation of primary human pancreatic islet cells leads to glucose-responsive pseudoislets comparable to native islets. J Cell Mol Med (2015) 0.84
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Size effect of engineered islets prepared using microfabricated wells on islet cell function and arrangement. Heliyon (2016) 0.77
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Tissue engineering approaches to cell-based type 1 diabetes therapy. Tissue Eng Part B Rev (2014) 0.77
Controlled local presentation of matrix proteins in microparticle-laden cell aggregates. Biotechnol Bioeng (2013) 0.77
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Progress and challenges of the bioartificial pancreas. Nano Converg (2016) 0.75
3-D Microwell Array System for Culturing Virus Infected Tumor Cells. Sci Rep (2016) 0.75
Microfluidics 3D gel-island chip for single cell isolation and lineage-dependent drug responses study. Lab Chip (2016) 0.75
PEG-peptide hydrogels reveal differential effects of matrix microenvironmental cues on melanoma drug sensitivity. Integr Biol (Camb) (2017) 0.75
Modeling tissue morphogenesis and cancer in 3D. Cell (2007) 7.49
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Controlling size, shape and homogeneity of embryoid bodies using poly(ethylene glycol) microwells. Lab Chip (2007) 2.30
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Controlled-size embryoid body formation in concave microwell arrays. Biomaterials (2010) 1.49
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Cell-cell communication mimicry with poly(ethylene glycol) hydrogels for enhancing beta-cell function. Proc Natl Acad Sci U S A (2011) 1.38
Complete protection of islets against allorejection and autoimmunity by a simple barium-alginate membrane. Diabetes (2001) 1.33
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Enhancing the reliability and throughput of neurosphere culture on hydrogel microwell arrays. Stem Cells (2008) 1.24
Hydrogel encapsulation environments functionalized with extracellular matrix interactions increase islet insulin secretion. Matrix Biol (2008) 1.23
Rat islet cell aggregates are superior to islets for transplantation in microcapsules. Diabetologia (2010) 1.14
MIN6 beta-cell-beta-cell interactions influence insulin secretory responses to nutrients and non-nutrients. Biochem Biophys Res Commun (2006) 1.04
Structure-function relationships in pancreatic islets: support for intraislet modulation of insulin secretion. Endocrinology (1985) 1.00
Autocrine-controlled formation and function of tissue-like aggregates by primary hepatocytes in micropatterned hydrogel arrays. Tissue Eng Part A (2011) 0.99
Rat pancreatic islet size standardization by the "hanging drop" technique. Transplant Proc (2007) 0.97
Tissue-engineered three-dimensional tumor models to study tumor angiogenesis. Tissue Eng Part A (2010) 0.96
Long-term biocompatibility, chemistry, and function of microencapsulated pancreatic islets. Biomaterials (2003) 0.94
Size-based separation and collection of mouse pancreatic islets for functional analysis. Biomed Microdevices (2010) 0.94
Microfabricated polyester conical microwells for cell culture applications. Lab Chip (2011) 0.92
Differentiating the effects of Cx36 and E-cadherin for proper insulin secretion of MIN6 cells. Exp Cell Res (2004) 0.92
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Surface characteristics and biocompatibility of lactide-based poly(ethylene glycol) scaffolds for tissue engineering. J Biomater Sci Polym Ed (1998) 0.84
Patterning of mono- and multilayered pancreatic beta-cell clusters. Langmuir (2010) 0.82
Dielectrophoretic assembly of insulinoma cells and fluorescent nanosensors into three-dimensional pseudo-islet constructs. IET Nanobiotechnol (2008) 0.82
Photodegradable hydrogels for dynamic tuning of physical and chemical properties. Science (2009) 5.68
Hydrogels as extracellular matrix mimics for 3D cell culture. Biotechnol Bioeng (2009) 4.72
Photoencapsulation of osteoblasts in injectable RGD-modified PEG hydrogels for bone tissue engineering. Biomaterials (2002) 4.45
Hydrogel properties influence ECM production by chondrocytes photoencapsulated in poly(ethylene glycol) hydrogels. J Biomed Mater Res (2002) 3.47
Sequential click reactions for synthesizing and patterning three-dimensional cell microenvironments. Nat Mater (2009) 3.29
Small functional groups for controlled differentiation of hydrogel-encapsulated human mesenchymal stem cells. Nat Mater (2008) 3.24
Materials science. Hydrogel cell cultures. Science (2007) 2.70
Photoinitiated polymerization of PEG-diacrylate with lithium phenyl-2,4,6-trimethylbenzoylphosphinate: polymerization rate and cytocompatibility. Biomaterials (2009) 2.65
Synthetic hydrogel niches that promote hMSC viability. Matrix Biol (2005) 2.61
Valvular myofibroblast activation by transforming growth factor-beta: implications for pathological extracellular matrix remodeling in heart valve disease. Circ Res (2004) 2.45
PEG hydrogels for the controlled release of biomolecules in regenerative medicine. Pharm Res (2008) 2.44
In situ elasticity modulation with dynamic substrates to direct cell phenotype. Biomaterials (2009) 2.41
Controlling the spatial distribution of ECM components in degradable PEG hydrogels for tissue engineering cartilage. J Biomed Mater Res A (2003) 2.37
Thermomechanics of the shape memory effect in polymers for biomedical applications. J Biomed Mater Res A (2005) 2.17
Photoreversible patterning of biomolecules within click-based hydrogels. Angew Chem Int Ed Engl (2011) 2.10
Cytocompatible click-based hydrogels with dynamically tunable properties through orthogonal photoconjugation and photocleavage reactions. Nat Chem (2011) 2.04
Three-dimensional growth and function of neural tissue in degradable polyethylene glycol hydrogels. Biomaterials (2005) 2.02
Encapsulating chondrocytes in degrading PEG hydrogels with high modulus: engineering gel structural changes to facilitate cartilaginous tissue production. Biotechnol Bioeng (2004) 1.97
Synthesis of photodegradable hydrogels as dynamically tunable cell culture platforms. Nat Protoc (2010) 1.92
The enhancement of chondrogenic differentiation of human mesenchymal stem cells by enzymatically regulated RGD functionalities. Biomaterials (2008) 1.82
Thiol-Yne Photopolymerizations: Novel Mechanism, Kinetics, and Step-Growth Formation of Highly Cross-Linked Networks. Macromolecules (2008) 1.81
Crosslinking density influences chondrocyte metabolism in dynamically loaded photocrosslinked poly(ethylene glycol) hydrogels. Ann Biomed Eng (2004) 1.79
The effect of heparin-functionalized PEG hydrogels on three-dimensional human mesenchymal stem cell osteogenic differentiation. Biomaterials (2006) 1.78
Characterization of valvular interstitial cell function in three dimensional matrix metalloproteinase degradable PEG hydrogels. Biomaterials (2009) 1.77
The performance of human mesenchymal stem cells encapsulated in cell-degradable polymer-peptide hydrogels. Biomaterials (2011) 1.75
Photocrosslinking of gelatin macromers to synthesize porous hydrogels that promote valvular interstitial cell function. Tissue Eng Part A (2009) 1.67
Chondrogenic differentiation potential of human mesenchymal stem cells photoencapsulated within poly(ethylene glycol)-arginine-glycine-aspartic acid-serine thiol-methacrylate mixed-mode networks. Tissue Eng (2007) 1.66
In vitro osteogenic differentiation of human mesenchymal stem cells photoencapsulated in PEG hydrogels. J Biomed Mater Res A (2004) 1.66
Manipulations in hydrogel chemistry control photoencapsulated chondrocyte behavior and their extracellular matrix production. J Biomed Mater Res A (2003) 1.63
Heparin functionalized PEG gels that modulate protein adsorption for hMSC adhesion and differentiation. Acta Biomater (2005) 1.62
Synthesis and characterization of a fluvastatin-releasing hydrogel delivery system to modulate hMSC differentiation and function for bone regeneration. Biomaterials (2006) 1.61
Mechanical properties of cellularly responsive hydrogels and their experimental determination. Adv Mater (2010) 1.60
Poly(ethylene glycol) hydrogels formed by thiol-ene photopolymerization for enzyme-responsive protein delivery. Biomaterials (2009) 1.56
Robust polymer microfluidic device fabrication via contact liquid photolithographic polymerization (CLiPP). Lab Chip (2004) 1.52
Crosslinked hyaluronan scaffolds as a biologically active carrier for valvular interstitial cells. Biomaterials (2005) 1.51
Nanobiomaterial applications in orthopedics. J Orthop Res (2007) 1.51
The effects of cell-matrix interactions on encapsulated beta-cell function within hydrogels functionalized with matrix-derived adhesive peptides. Biomaterials (2007) 1.51
Functional PEG-peptide hydrogels to modulate local inflammation induced by the pro-inflammatory cytokine TNFalpha. Biomaterials (2009) 1.49
Activation of valvular interstitial cells is mediated by transforming growth factor-beta1 interactions with matrix molecules. Matrix Biol (2005) 1.49
Spatial and temporal control of the alkyne-azide cycloaddition by photoinitiated Cu(II) reduction. Nat Chem (2011) 1.48
Three-dimensional biochemical patterning of click-based composite hydrogels via thiolene photopolymerization. Biomacromolecules (2008) 1.46
Delivery of osteoinductive growth factors from degradable PEG hydrogels influences osteoblast differentiation and mineralization. J Control Release (2002) 1.46
PEG-based hydrogels as an in vitro encapsulation platform for testing controlled beta-cell microenvironments. Acta Biomater (2005) 1.46
Designing scaffolds for valvular interstitial cells: cell adhesion and function on naturally derived materials. J Biomed Mater Res A (2004) 1.43
Tunable hydrogels for external manipulation of cellular microenvironments through controlled photodegradation. Adv Mater (2010) 1.42
The effect of ethylene glycol methacrylate phosphate in PEG hydrogels on mineralization and viability of encapsulated hMSCs. Biomaterials (2005) 1.42
Redirecting valvular myofibroblasts into dormant fibroblasts through light-mediated reduction in substrate modulus. PLoS One (2012) 1.41
Cell-matrix interactions improve beta-cell survival and insulin secretion in three-dimensional culture. Tissue Eng Part A (2008) 1.40
Cell-cell communication mimicry with poly(ethylene glycol) hydrogels for enhancing beta-cell function. Proc Natl Acad Sci U S A (2011) 1.38
Dexamethasone-functionalized gels induce osteogenic differentiation of encapsulated hMSCs. J Biomed Mater Res A (2006) 1.38
Encapsulating chondrocytes in copolymer gels: bimodal degradation kinetics influence cell phenotype and extracellular matrix development. J Biomed Mater Res A (2004) 1.37
Fibroblast growth factor represses Smad-mediated myofibroblast activation in aortic valvular interstitial cells. FASEB J (2008) 1.37
Macromolecular Monomers for the Synthesis of Hydrogel Niches and Their Application in Cell Encapsulation and Tissue Engineering. Prog Polym Sci (2008) 1.36
The influence of the RGD peptide motif and its contextual presentation in PEG gels on human mesenchymal stem cell viability. J Tissue Eng Regen Med (2008) 1.36
Degradable thiol-acrylate photopolymers: polymerization and degradation behavior of an in situ forming biomaterial. Biomaterials (2005) 1.34
Effects of PEG hydrogel crosslinking density on protein diffusion and encapsulated islet survival and function. J Biomed Mater Res A (2009) 1.34
Synthesis and characterization of photocrosslinkable, degradable poly(vinyl alcohol)-based tissue engineering scaffolds. Biomaterials (2002) 1.33
Delivering DNA from photocrosslinked, surface eroding polyanhydrides. J Control Release (2004) 1.32
Advances in bioactive hydrogels to probe and direct cell fate. Annu Rev Chem Biomol Eng (2012) 1.32
Peptide-Functionalized Click Hydrogels with Independently Tunable Mechanics and Chemical Functionality for 3D Cell Culture. Chem Mater (2010) 1.32
The effect on osteoblast function of colocalized RGD and PHSRN epitopes on PEG surfaces. Biomaterials (2005) 1.31
DNA delivery from photocrosslinked PEG hydrogels: encapsulation efficiency, release profiles, and DNA quality. J Control Release (2004) 1.31
Incorporation of tissue-specific molecules alters chondrocyte metabolism and gene expression in photocrosslinked hydrogels. Acta Biomater (2004) 1.29
Crosslinking density influences the morphology of chondrocytes photoencapsulated in PEG hydrogels during the application of compressive strain. J Orthop Res (2004) 1.29
Substrate properties influence calcification in valvular interstitial cell culture. J Heart Valve Dis (2008) 1.28
Controlling Affinity Binding with Peptide-Functionalized Poly(ethylene glycol) Hydrogels. Adv Funct Mater (2009) 1.26
A synthetic strategy for mimicking the extracellular matrix provides new insight about tumor cell migration. Integr Biol (Camb) (2009) 1.25
Hydrogel encapsulation environments functionalized with extracellular matrix interactions increase islet insulin secretion. Matrix Biol (2008) 1.23
Exogenously triggered, enzymatic degradation of photopolymerized hydrogels with polycaprolactone subunits: experimental observation and modeling of mass loss behavior. Biomacromolecules (2006) 1.21
Hydrogels preserve native phenotypes of valvular fibroblasts through an elasticity-regulated PI3K/AKT pathway. Proc Natl Acad Sci U S A (2013) 1.20
Photoinitiated crosslinked degradable copolymer networks for tissue engineering applications. Biomaterials (2003) 1.19
Synthetically tractable click hydrogels for three-dimensional cell culture formed using tetrazine-norbornene chemistry. Biomacromolecules (2013) 1.17
Small peptide functionalized thiol-ene hydrogels as culture substrates for understanding valvular interstitial cell activation and de novo tissue deposition. Acta Biomater (2012) 1.16
Statins block calcific nodule formation of valvular interstitial cells by inhibiting alpha-smooth muscle actin expression. Arterioscler Thromb Vasc Biol (2009) 1.16
Cross-linking and degradation of step-growth hydrogels formed by thiol-ene photoclick chemistry. Biomacromolecules (2012) 1.15
Thiol-ene photopolymerizations provide a facile method to encapsulate proteins and maintain their bioactivity. Biomacromolecules (2012) 1.15
Tailoring the degradation of hydrogels formed from multivinyl poly(ethylene glycol) and poly(vinyl alcohol) macromers for cartilage tissue engineering. Biomacromolecules (2003) 1.12
Controlling cartilaginous matrix evolution in hydrogels with degradation triggered by exogenous addition of an enzyme. Tissue Eng (2007) 1.12
Enzyme-mediated redox initiation for hydrogel generation and cellular encapsulation. Biomacromolecules (2009) 1.12
Manipulations in hydrogel degradation behavior enhance osteoblast function and mineralized tissue formation. Tissue Eng (2006) 1.11
Student award for outstanding research winner in the Ph.D. category for the 9th World Biomaterials Congress, Chengdu, China, June 1-5, 2012: synthesis and application of photodegradable microspheres for spatiotemporal control of protein delivery. J Biomed Mater Res A (2012) 1.11
Material-based regulation of the myofibroblast phenotype. Biomaterials (2007) 1.11
Gene delivery in tissue engineering: a photopolymer platform to coencapsulate cells and plasmid DNA. Pharm Res (2003) 1.11
Multifunctional hydrogels that promote osteogenic hMSC differentiation through stimulation and sequestering of BMP2. Adv Funct Mater (2007) 1.10
Controlled two-photon photodegradation of PEG hydrogels to study and manipulate subcellular interactions on soft materials. Soft Matter (2010) 1.10
Glucagon-like peptide-1 functionalized PEG hydrogels promote survival and function of encapsulated pancreatic beta-cells. Biomacromolecules (2009) 1.10
Synthesis of immunoisolation barriers that provide localized immunosuppression for encapsulated pancreatic islets. Bioconjug Chem (2006) 1.09
Biophysically defined and cytocompatible covalently adaptable networks as viscoelastic 3D cell culture systems. Adv Mater (2013) 1.08
Kinetic chain lengths in highly cross-linked networks formed by the photoinitiated polymerization of divinyl monomers: a gel permeation chromatography investigation. Biomacromolecules (2003) 1.08
Gel Permeation Chromatography Characterization of the Chain Length Distributions in Thiol-Acrylate Photopolymer Networks. Macromolecules (2006) 1.07
Human neutrophil elastase responsive delivery from poly(ethylene glycol) hydrogels. Biomacromolecules (2009) 1.07
The effect of bioactive hydrogels on the secretion of extracellular matrix molecules by valvular interstitial cells. Biomaterials (2008) 1.07
Wnt5a directs polarized calcium gradients by recruiting cortical endoplasmic reticulum to the cell trailing edge. Dev Cell (2013) 1.07
An initial investigation of photocurable three-dimensional lactic acid based scaffolds in a critical-sized cranial defect. Biomaterials (2003) 1.05
Integrin-linked kinase production prevents anoikis in human mesenchymal stem cells. J Biomed Mater Res A (2007) 1.05
Hemodynamic and cellular response feedback in calcific aortic valve disease. Circ Res (2013) 1.05
Glucose oxidase-mediated polymerization as a platform for dual-mode signal amplification and biodetection. Biotechnol Bioeng (2011) 1.05
Dynamic microenvironments: the fourth dimension. Sci Transl Med (2012) 1.04
Regulating MCP-1 diffusion in affinity hydrogels for enhancing immuno-isolation. J Control Release (2009) 1.04