| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial.
|
Lancet
|
2002
|
14.14
|
|
2
|
Infliximab maintenance therapy for fistulizing Crohn's disease.
|
N Engl J Med
|
2004
|
6.77
|
|
3
|
Adalimumab induces and maintains clinical remission in patients with moderate-to-severe ulcerative colitis.
|
Gastroenterology
|
2011
|
5.38
|
|
4
|
Comparison of scheduled and episodic treatment strategies of infliximab in Crohn's disease.
|
Gastroenterology
|
2004
|
4.26
|
|
5
|
Natalizumab for the treatment of active Crohn's disease: results of the ENCORE Trial.
|
Gastroenterology
|
2007
|
3.32
|
|
6
|
Scheduled maintenance treatment with infliximab is superior to episodic treatment for the healing of mucosal ulceration associated with Crohn's disease.
|
Gastrointest Endosc
|
2006
|
2.73
|
|
7
|
Adalimumab induces and maintains mucosal healing in patients with Crohn's disease: data from the EXTEND trial.
|
Gastroenterology
|
2012
|
2.03
|
|
8
|
Best practices for use of historical control data of proliferative rodent lesions.
|
Toxicol Pathol
|
2009
|
1.79
|
|
9
|
Tacrolimus for the treatment of fistulas in patients with Crohn's disease: a randomized, placebo-controlled trial.
|
Gastroenterology
|
2003
|
1.70
|
|
10
|
Placental transfer of anti-tumor necrosis factor agents in pregnant patients with inflammatory bowel disease.
|
Clin Gastroenterol Hepatol
|
2012
|
1.57
|
|
11
|
Quality indicators for inflammatory bowel disease: development of process and outcome measures.
|
Inflamm Bowel Dis
|
2013
|
1.33
|
|
12
|
Certolizumab pegol in patients with moderate to severe Crohn's disease and secondary failure to infliximab.
|
Clin Gastroenterol Hepatol
|
2010
|
1.19
|
|
13
|
A 21st century roadmap for human health risk assessment.
|
Crit Rev Toxicol
|
2014
|
1.07
|
|
14
|
Risk assessment in the 21st century: roadmap and matrix.
|
Crit Rev Toxicol
|
2014
|
0.95
|
|
15
|
Use of the spontaneous Tsc2 knockout (Eker) rat model of hereditary renal cell carcinoma for the study of renal carcinogens.
|
Toxicol Pathol
|
2003
|
0.94
|
|
16
|
Gene profiling in the livers of wild-type and PPARalpha-null mice exposed to perfluorooctanoic acid.
|
Toxicol Pathol
|
2008
|
0.93
|
|
17
|
Reproductive and developmental toxicity of arsenic in rodents: a review.
|
Int J Toxicol
|
2006
|
0.92
|
|
18
|
Coordinated changes in xenobiotic metabolizing enzyme gene expression in aging male rats.
|
Toxicol Sci
|
2008
|
0.91
|
|
19
|
Atrazine-induced reproductive tract alterations after transplacental and/or lactational exposure in male Long-Evans rats.
|
Toxicol Appl Pharmacol
|
2006
|
0.90
|
|
20
|
Disruption of testosterone homeostasis as a mode of action for the reproductive toxicity of triazole fungicides in the male rat.
|
Toxicol Sci
|
2006
|
0.90
|
|
21
|
Pilot feasibility studies of leukocytapheresis with the Adacolumn Apheresis System in patients with active ulcerative colitis or Crohn disease.
|
J Clin Gastroenterol
|
2006
|
0.89
|
|
22
|
Metamorphic inhibition of Xenopus laevis by sodium perchlorate: effects on development and thyroid histology.
|
Environ Toxicol Chem
|
2005
|
0.89
|
|
23
|
Gene expression profiling of responses to dimethylarsinic acid in female F344 rat urothelium.
|
Toxicology
|
2005
|
0.87
|
|
24
|
Identification and characterization of adverse effects in 21st century toxicology.
|
Toxicol Sci
|
2012
|
0.87
|
|
25
|
Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activator.
|
Crit Rev Toxicol
|
2013
|
0.86
|
|
26
|
The effect of chronic progressive nephropathy on the incidence of renal tubule cell neoplasms in control male F344 rats.
|
Toxicol Pathol
|
2003
|
0.85
|
|
27
|
A tiered approach to systemic toxicity testing for agricultural chemical safety assessment.
|
Crit Rev Toxicol
|
2006
|
0.85
|
|
28
|
Transcriptional profile of diuron-induced toxicity on the urinary bladder of male Wistar rats to inform mode of action.
|
Toxicol Sci
|
2011
|
0.84
|
|
29
|
Effects of prenatal exposure to a low dose atrazine metabolite mixture on pubertal timing and prostate development of male Long-Evans rats.
|
Reprod Toxicol
|
2010
|
0.83
|
|
30
|
A data-based assessment of alternative strategies for identification of potential human cancer hazards.
|
Toxicol Pathol
|
2009
|
0.83
|
|
31
|
Propiconazole-induced cytochrome P450 gene expression and enzymatic activities in rat and mouse liver.
|
Toxicol Lett
|
2005
|
0.82
|
|
32
|
What do we need to know prior to thinking about incorporating an epigenetic evaluation into safety assessments?
|
Toxicol Sci
|
2010
|
0.82
|
|
33
|
Oxidative DNA damage from potassium bromate exposure in Long-Evans rats is not enhanced by a mixture of drinking water disinfection by-products.
|
Chem Biol Interact
|
2005
|
0.81
|
|
34
|
Tissue distribution and urinary excretion of dimethylated arsenic and its metabolites in dimethylarsinic acid- or arsenate-treated rats.
|
Toxicol Appl Pharmacol
|
2007
|
0.81
|
|
35
|
Gene expression profiling in the liver of CD-1 mice to characterize the hepatotoxicity of triazole fungicides.
|
Toxicol Appl Pharmacol
|
2006
|
0.81
|
|
36
|
Gene expression profiling in liver and testis of rats to characterize the toxicity of triazole fungicides.
|
Toxicol Appl Pharmacol
|
2006
|
0.80
|
|
37
|
Thyroid histopathology assessments for the amphibian metamorphosis assay to detect thyroid-active substances.
|
Toxicol Pathol
|
2009
|
0.80
|
|
38
|
Effect of conazole fungicides on reproductive development in the female rat.
|
Reprod Toxicol
|
2006
|
0.80
|
|
39
|
Transcriptional profiles in liver from mice treated with hepatotumorigenic and nonhepatotumorigenic triazole conazole fungicides: Propiconazole, triadimefon, and myclobutanil.
|
Toxicol Pathol
|
2006
|
0.80
|
|
40
|
Identification of interspecies concordance of mechanisms of arsenic-induced bladder cancer.
|
Toxicol In Vitro
|
2007
|
0.80
|
|
41
|
Toxicity profiles in mice treated with hepatotumorigenic and non-hepatotumorigenic triazole conazole fungicides: Propiconazole, triadimefon, and myclobutanil.
|
Toxicol Pathol
|
2006
|
0.79
|
|
42
|
Potential for a global historical control database for proliferative rodent lesions.
|
Toxicol Pathol
|
2009
|
0.79
|
|
43
|
A randomised, double-blind, sham-controlled study of granulocyte/monocyte apheresis for moderate to severe Crohn's disease.
|
Gut
|
2012
|
0.79
|
|
44
|
Formaldehyde-induced gene expression in F344 rat nasal respiratory epithelium.
|
Toxicology
|
2003
|
0.79
|
|
45
|
Crohn's colitis presenting with node-negative colon cancer and liver metastasis after therapy with infliximab: report of two cases.
|
Dis Colon Rectum
|
2005
|
0.78
|
|
46
|
Dimethylarsinic acid in drinking water changed the morphology of urinary bladder but not the expression of DNA repair genes of bladder transitional epithelium in F344 rats.
|
Toxicol Pathol
|
2009
|
0.78
|
|
47
|
Transcriptional profiles in liver from rats treated with tumorigenic and non-tumorigenic triazole conazole fungicides: Propiconazole, triadimefon, and myclobutanil.
|
Toxicol Pathol
|
2006
|
0.78
|
|
48
|
Fluconazole-induced hepatic cytochrome P450 gene expression and enzymatic activities in rats and mice.
|
Toxicol Lett
|
2006
|
0.78
|
|
49
|
Induction of transitional cell hyperplasia in the urinary bladder and aberrant crypt foci in the colon of rats treated with individual and a mixture of drinking water disinfection by-products.
|
Toxicol Pathol
|
2003
|
0.78
|
|
50
|
Analysis of preneoplastic and neoplastic renal lesions in Tsc2 mutant Long-Evans (Eker) rats following exposure to a mixture of drinking water disinfection by-products.
|
Toxicology
|
2003
|
0.77
|
|
51
|
The transcriptional profile of the kidney in Tsc2 heterozygous mutant Long Evans (Eker) rats compared to wild-type.
|
Mutat Res
|
2004
|
0.77
|
|
52
|
Workshop overview: arsenic research and risk assessment.
|
Toxicol Appl Pharmacol
|
2007
|
0.77
|
|
53
|
The carcinogenic response of Tsc2 mutant Long-Evans (Eker) rats to a mixture of drinking water disinfection by-products was less than additive.
|
Toxicol Sci
|
2002
|
0.77
|
|
54
|
Finfish and aquatic invertebrate pathology resources for now and the future.
|
Comp Biochem Physiol C Toxicol Pharmacol
|
2008
|
0.77
|
|
55
|
Computational toxicology: framework, partnerships, and program development. September 29-30, 2003, Research Triangle Park, North Carolina.
|
Reprod Toxicol
|
2005
|
0.77
|
|
56
|
Arsenate and dimethylarsinic acid in drinking water did not affect DNA damage repair in urinary bladder transitional cells or micronuclei in bone marrow.
|
Environ Mol Mutagen
|
2009
|
0.76
|
|
57
|
Single or group housing altered hormonal physiology and affected pituitary and interstitial cell kinetics.
|
J Toxicol Sci
|
2002
|
0.76
|
|
58
|
A mixture of ammonium perchlorate and sodium chlorate enhances alterations of the pituitary-thyroid axis caused by the individual chemicals in adult male F344 rats.
|
Toxicol Pathol
|
2005
|
0.76
|
|
59
|
Transcriptional Modulation of the ERK1/2 MAPK and NF-κB Pathways in Human Urothelial Cells After Trivalent Arsenical Exposure: Implications for Urinary Bladder Cancer.
|
J Can Res Updates
|
2012
|
0.76
|
|
60
|
Predicting Outcomes and Tailoring Therapy in the Diagnosis and Treatment of IBD.
|
Gastroenterol Hepatol (N Y)
|
2007
|
0.75
|
|
61
|
Pathology peer review.
|
Toxicol Pathol
|
2010
|
0.75
|
|
62
|
Mutations in the VHL gene from potassium bromate-induced rat clear cell renal tumors.
|
Cancer Lett
|
2002
|
0.75
|
|
63
|
Normal gene expression in male F344 rat nasal transitional and respiratory epithelium.
|
Gene
|
2002
|
0.75
|
|
64
|
Effects of Transient and Persistent Anti-drug Antibodies to Certolizumab Pegol: Longitudinal Data from a 7-Year Study in Crohn's Disease.
|
Inflamm Bowel Dis
|
2017
|
0.75
|