PubRank

Per Jemth

Author PubWeight™ 44.95‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Demonstration of long-range interactions in a PDZ domain by NMR, kinetics, and protein engineering. Structure 2006 1.41
2 A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage. Proc Natl Acad Sci U S A 2012 1.40
3 Reassessing a sparse energetic network within a single protein domain. Proc Natl Acad Sci U S A 2008 1.33
4 Simulation and experiment conspire to reveal cryptic intermediates and a slide from the nucleation-condensation to framework mechanism of folding. J Mol Biol 2005 1.27
5 Helical propensity in an intrinsically disordered protein accelerates ligand binding. Angew Chem Int Ed Engl 2014 1.16
6 Fibroblast growth factors share binding sites in heparan sulphate. Biochem J 2005 1.15
7 Nitrocellulose filter binding to assess binding of glycosaminoglycans to proteins. Methods Enzymol 2003 1.11
8 Comparison of successive transition states for folding reveals alternative early folding pathways of two homologous proteins. Proc Natl Acad Sci U S A 2008 1.10
9 Single molecule unfolding and stretching of protein domains inside a solid-state nanopore by electric field. Sci Rep 2013 1.09
10 A PDZ domain recapitulates a unifying mechanism for protein folding. Proc Natl Acad Sci U S A 2006 1.06
11 Investigating the structural plasticity of a cytochrome P450: three-dimensional structures of P450 EryK and binding to its physiological substrate. J Biol Chem 2009 1.06
12 The transition state structure for coupled binding and folding of disordered protein domains. Sci Rep 2013 1.04
13 A sequential binding mechanism in a PDZ domain. Biochemistry 2009 1.03
14 The kinetics of PDZ domain-ligand interactions and implications for the binding mechanism. J Biol Chem 2005 1.03
15 A conserved folding mechanism for PDZ domains. FEBS Lett 2007 1.03
16 Identification and characterization of protein folding intermediates. Biophys Chem 2007 1.03
17 Fast association and slow transitions in the interaction between two intrinsically disordered protein domains. J Biol Chem 2012 1.02
18 The binding mechanisms of intrinsically disordered proteins. Phys Chem Chem Phys 2013 1.00
19 Two conserved residues govern the salt and pH dependencies of the binding reaction of a PDZ domain. J Biol Chem 2006 1.00
20 Sequence-specific long range networks in PSD-95/discs large/ZO-1 (PDZ) domains tune their binding selectivity. J Biol Chem 2011 0.99
21 Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDA receptor interaction. Angew Chem Int Ed Engl 2009 0.97
22 Modified peptides as potent inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction. J Med Chem 2008 0.96
23 An on-pathway intermediate in the folding of a PDZ domain. J Biol Chem 2007 0.96
24 Chemical, thermal, and electric field induced unfolding of single protein molecules studied using nanopores. Anal Chem 2011 0.93
25 Processing of macromolecular heparin by heparanase. J Biol Chem 2003 0.91
26 Folding pathways of proteins with increasing degree of sequence identities but different structure and function. Proc Natl Acad Sci U S A 2012 0.91
27 Single-molecule studies of intrinsically disordered proteins using solid-state nanopores. Anal Chem 2013 0.89
28 The plastic energy landscape of protein folding: a triangular folding mechanism with an equilibrium intermediate for a small protein domain. J Biol Chem 2010 0.89
29 An ensemble of theta class glutathione transferases with novel catalytic properties generated by stochastic recombination of fragments of two mammalian enzymes. J Mol Biol 2002 0.89
30 The transition state of coupled folding and binding for a flexible β-finger. J Mol Biol 2012 0.88
31 Deciphering the kinetic binding mechanism of dimeric ligands using a potent plasma-stable dimeric inhibitor of postsynaptic density protein-95 as an example. J Biol Chem 2010 0.87
32 Interactions outside the boundaries of the canonical binding groove of a PDZ domain influence ligand binding. Biochemistry 2012 0.86
33 Side-chain interactions form late and cooperatively in the binding reaction between disordered peptides and PDZ domains. J Am Chem Soc 2011 0.86
34 Energetic pathway sampling in a protein interaction domain. Structure 2013 0.85
35 Distinguishing between smooth and rough free energy barriers in protein folding. Biochemistry 2009 0.85
36 Biophysical characterization of the complex between human papillomavirus E6 protein and synapse-associated protein 97. J Biol Chem 2010 0.85
37 An expanded view of the protein folding landscape of PDZ domains. Biochem Biophys Res Commun 2012 0.85
38 Folding and stability of globular proteins and implications for function. Curr Opin Struct Biol 2009 0.84
39 Ligand binding by PDZ domains. Biofactors 2012 0.83
40 Structural and functional characterization of CcmG from Pseudomonas aeruginosa, a key component of the bacterial cytochrome c maturation apparatus. Proteins 2010 0.82
41 Tolerance of protein folding to a circular permutation in a PDZ domain. PLoS One 2012 0.82
42 Probing the role of backbone hydrogen bonds in protein-peptide interactions by amide-to-ester mutations. J Am Chem Soc 2013 0.79
43 Rigidified clicked dimeric ligands for studying the dynamics of the PDZ1-2 supramodule of PSD-95. Chembiochem 2014 0.76
44 Thermodynamic aspects of cAMP dependent protein kinase catalytic subunit allostery. Protein J 2014 0.76
45 Characterization of the endopeptidase activity of tripeptidyl-peptidase II. Biochem Biophys Res Commun 2012 0.76
46 Nonequilibrium capture rates induce protein accumulation and enhanced adsorption to solid-state nanopores. ACS Nano 2014 0.76
47 A semisynthetic glutathione peroxidase with high catalytic efficiency. Selenoglutathione transferase. Chem Biol 2002 0.76
48 Conserved nucleation sites reinforce the significance of Phi value analysis in protein-folding studies. IUBMB Life 2014 0.75
49 Kinetics of acrylodan-labelled cAMP-dependent protein kinase catalytic subunit denaturation. Protein J 2013 0.75