Experience in international clinical research: the HIV Prevention Trials Network.

PubWeight™: 0.84‹?›

🔗 View Article (PMID 22348195)

Published in Clin Investig (Lond) on December 01, 2011


Nirupama Deshmane Sista1, Quarraisha Abdool Karim, Kathy Hinson, Deborah Donnell, Susan H Eshleman, Sten H Vermund

Author Affiliations

1: FHI 360, Inc., Durham, NC, USA.

Articles cited by this

Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med (2011) 69.36

Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med (2010) 50.17

Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science (2010) 35.19

Rates of HIV-1 transmission per coital act, by stage of HIV-1 infection, in Rakai, Uganda. J Infect Dis (2005) 21.08

Young people's sexual health in South Africa: HIV prevalence and sexual behaviors from a nationally representative household survey. AIDS (2005) 8.71

HIV infection and tuberculosis in South Africa: an urgent need to escalate the public health response. Lancet (2009) 6.96

Human immunodeficiency virus (HIV) risk, prevention, and testing behaviors--United States, National HIV Behavioral Surveillance System: men who have sex with men, November 2003-April 2005. MMWR Surveill Summ (2006) 5.15

Acute HIV-1 Infection. N Engl J Med (2011) 4.84

Community-based intervention to increase HIV testing and case detection in people aged 16-32 years in Tanzania, Zimbabwe, and Thailand (NIMH Project Accept, HPTN 043): a randomised study. Lancet Infect Dis (2011) 4.72

Treatment to prevent transmission of HIV-1. Clin Infect Dis (2010) 4.54

HIV prevention transformed: the new prevention research agenda. Lancet (2011) 4.23

Project Accept (HPTN 043): a community-based intervention to reduce HIV incidence in populations at risk for HIV in sub-Saharan Africa and Thailand. J Acquir Immune Defic Syndr (2008) 3.83

Safety and effectiveness of BufferGel and 0.5% PRO2000 gel for the prevention of HIV infection in women. AIDS (2011) 2.86

Combination HIV prevention: significance, challenges, and opportunities. Curr HIV/AIDS Rep (2011) 2.72

AIDS in America--forgotten but not gone. N Engl J Med (2010) 2.56

The spread, treatment, and prevention of HIV-1: evolution of a global pandemic. J Clin Invest (2008) 2.12

HIV risk behaviors in sub-Saharan Africa and Northern Thailand: baseline behavioral data from Project Accept. J Acquir Immune Defic Syndr (2008) 2.06

HIV-related stigma, social norms, and HIV testing in Soweto and Vulindlela, South Africa: National Institutes of Mental Health Project Accept (HPTN 043). J Acquir Immune Defic Syndr (2010) 1.78

Thirty years of HIV and AIDS: future challenges and opportunities. Ann Intern Med (2011) 1.56

Test and tell: correlates and consequences of testing and disclosure of HIV status in South Africa (HPTN 043 Project Accept). J Acquir Immune Defic Syndr (2009) 1.53

Addressing research priorities for prevention of HIV infection in the United States. Clin Infect Dis (2010) 1.46

Implementation science for the prevention and treatment of HIV/AIDS. J Acquir Immune Defic Syndr (2010) 1.44

No "magic bullet": exploring community mobilization strategies used in a multi-site community based randomized controlled trial: Project Accept (HPTN 043). AIDS Behav (2012) 1.29

Challenges of a hidden epidemic: HIV prevention among women in the United States. J Acquir Immune Defic Syndr (2010) 1.27

Antiretroviral therapy as HIV prevention: status and prospects. Am J Public Health (2010) 1.25

How effective are risk-reduction interventions targeting injecting drug users? AIDS (1994) 1.20

HIV prevention research: taking stock and the way forward. AIDS (2010) 1.13

Predictors of HIV transmission risk behavior and seroconversion among Latino men who have sex with men in Project EXPLORE. AIDS Behav (2012) 1.13

Male circumcision and risk of HIV acquisition among MSM. AIDS (2011) 1.06

Controlling and ultimately ending the HIV/AIDS pandemic: a feasible goal. JAMA (2010) 0.97


Antiretrovirals for HIV prevention: translating promise into praxis. Lancet (2011) 0.97

A post-trial assessment of factors influencing study drug adherence in a randomized biomedical HIV-1 prevention trial. AIDS Behav (2011) 0.93

Are there adverse consequences of quizzing during informed consent for HIV research? J Med Ethics (2011) 0.93

Nelfinavir and Lamivudine pharmacokinetics during the first two weeks of life. Pediatr Infect Dis J (2011) 0.92

HIV prevention 2010: where are we now and where are we going? Curr Opin HIV AIDS (2010) 0.91

HPTN 052 and the future of HIV treatment and prevention. Lancet (2011) 0.89

Current Status of HIV/AIDS in South Asia. J Glob Infect Dis (2009) 0.88

Chemoprophylaxis for HIV prevention: new opportunities and new questions. J Acquir Immune Defic Syndr (2010) 0.82

HIV epidemiology, testing strategies, and prevention interventions. Top HIV Med (2010) 0.81

Good intentions: risk factors for unintended pregnancies in the US cohort of a microbicide trial. Contraception (2010) 0.79

Articles by these authors

Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med (2011) 69.36

Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. N Engl J Med (2012) 27.84

Use of hormonal contraceptives and risk of HIV-1 transmission: a prospective cohort study. Lancet Infect Dis (2011) 10.96

Timing of initiation of antiretroviral drugs during tuberculosis therapy. N Engl J Med (2010) 10.90

Integration of antiretroviral therapy with tuberculosis treatment. N Engl J Med (2011) 5.31

Genital HIV-1 RNA predicts risk of heterosexual HIV-1 transmission. Sci Transl Med (2011) 5.21

Prevention of mother-to-child transmission of HIV in Africa: successes and challenges in scaling-up a nevirapine-based program in Lusaka, Zambia. AIDS (2003) 4.82

Safety and tolerability of tenofovir vaginal gel in abstinent and sexually active HIV-infected and uninfected women. AIDS (2006) 4.23

Rethinking prevention of HIV type 1 infection. Clin Infect Dis (2010) 4.19

Antiretroviral treatment for children with peripartum nevirapine exposure. N Engl J Med (2010) 3.81

Prevalence and predictors of squamous intraepithelial lesions of the cervix in HIV-infected women in Lusaka, Zambia. Gynecol Oncol (2006) 3.68

Tenofovir Gel for the Prevention of Herpes Simplex Virus Type 2 Infection. N Engl J Med (2015) 3.64

Increased risk of HIV-1 transmission in pregnancy: a prospective study among African HIV-1-serodiscordant couples. AIDS (2011) 3.61

Sensitive drug-resistance assays reveal long-term persistence of HIV-1 variants with the K103N nevirapine (NVP) resistance mutation in some women and infants after the administration of single-dose NVP: HIVNET 012. J Infect Dis (2005) 3.59

Establishing a cohort at high risk of HIV infection in South Africa: challenges and experiences of the CAPRISA 002 acute infection study. PLoS One (2008) 3.40

Achieving the health Millennium Development Goals for South Africa: challenges and priorities. Lancet (2009) 3.35

Characteristics of HIV-1 serodiscordant couples enrolled in a clinical trial of antiretroviral pre-exposure prophylaxis for HIV-1 prevention. PLoS One (2011) 3.27

Effectiveness of a city-wide program to prevent mother-to-child HIV transmission in Lusaka, Zambia. AIDS (2005) 2.97

Comparison of two strategies for administering nevirapine to prevent perinatal HIV transmission in high-prevalence, resource-poor settings. J Acquir Immune Defic Syndr (2003) 2.97

Does douching increase risk for sexually transmitted infections? A prospective study in high-risk adolescents. Am J Obstet Gynecol (2008) 2.96

Impact of small reductions in plasma HIV RNA levels on the risk of heterosexual transmission and disease progression. AIDS (2008) 2.91

HIV/AIDS epidemiology, pathogenesis, prevention, and treatment. Lancet (2006) 2.86

Combination HIV prevention: significance, challenges, and opportunities. Curr HIV/AIDS Rep (2011) 2.72

LigAmp for sensitive detection of single-nucleotide differences. Nat Methods (2004) 2.70

Effect of treating co-infections on HIV-1 viral load: a systematic review. Lancet Infect Dis (2010) 2.60

Nevirapine versus ritonavir-boosted lopinavir for HIV-infected children. N Engl J Med (2012) 2.50

Efficacy and safety of an extended nevirapine regimen in infant children of breastfeeding mothers with HIV-1 infection for prevention of postnatal HIV-1 transmission (HPTN 046): a randomised, double-blind, placebo-controlled trial. Lancet (2011) 2.49

Estimating the impact of plasma HIV-1 RNA reductions on heterosexual HIV-1 transmission risk. PLoS One (2010) 2.48

Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape. Nat Med (2012) 2.48

HIV incidence determination in the United States: a multiassay approach. J Infect Dis (2012) 2.47

Hepatitis C virus infection in former commercial plasma/blood donors in rural Shanxi Province, China: the China Integrated Programs for Research on AIDS. J Infect Dis (2005) 2.47

Physician emigration from sub-Saharan Africa to the United States: analysis of the 2011 AMA physician masterfile. PLoS Med (2013) 2.47

Adherence to antiretroviral prophylaxis for HIV prevention: a substudy cohort within a clinical trial of serodiscordant couples in East Africa. PLoS Med (2013) 2.44

Implementation of 'see-and-treat' cervical cancer prevention services linked to HIV care in Zambia. AIDS (2009) 2.42

Predictors of successful early infant diagnosis of HIV in a rural district hospital in Zambézia, Mozambique. J Acquir Immune Defic Syndr (2011) 2.39

Co-infection with HIV and hepatitis C virus in former plasma/blood donors: challenge for patient care in rural China. AIDS (2006) 2.36

Correlates of HIV acquisition in a cohort of Black men who have sex with men in the United States: HIV prevention trials network (HPTN) 061. PLoS One (2013) 2.32

Does severity of HIV disease in HIV-infected mothers affect mortality and morbidity among their uninfected infants? Clin Infect Dis (2005) 2.32

Advancing cervical cancer prevention initiatives in resource-constrained settings: insights from the Cervical Cancer Prevention Program in Zambia. PLoS Med (2011) 2.28

Early clinical and immune response to NNRTI-based antiretroviral therapy among women with prior exposure to single-dose nevirapine. AIDS (2007) 2.19

Sexual behaviour of heterosexual men and women receiving antiretroviral pre-exposure prophylaxis for HIV prevention: a longitudinal analysis. Lancet Infect Dis (2013) 2.18

Incorrect identification of recent HIV infection in adults in the United States using a limiting-antigen avidity assay. AIDS (2014) 2.18

Childhood sexual abuse is highly associated with HIV risk-taking behavior and infection among MSM in the EXPLORE Study. J Acquir Immune Defic Syndr (2009) 2.17

A randomized trial of the intrauterine contraceptive device vs hormonal contraception in women who are infected with the human immunodeficiency virus. Am J Obstet Gynecol (2007) 2.17

Coreceptor tropism in human immunodeficiency virus type 1 subtype D: high prevalence of CXCR4 tropism and heterogeneous composition of viral populations. J Virol (2007) 2.14

Hepatitis B and hepatitis C in Pakistan: prevalence and risk factors. Int J Infect Dis (2008) 2.13

The efficacy of a network intervention to reduce HIV risk behaviors among drug users and risk partners in Chiang Mai, Thailand and Philadelphia, USA. Soc Sci Med (2008) 2.10

Bacterial vaginosis associated with increased risk of female-to-male HIV-1 transmission: a prospective cohort analysis among African couples. PLoS Med (2012) 2.06

HPTN 071 (PopART): rationale and design of a cluster-randomised trial of the population impact of an HIV combination prevention intervention including universal testing and treatment - a study protocol for a cluster randomised trial. Trials (2014) 1.94

Quantitative analysis of HIV-1 variants with the K103N resistance mutation after single-dose nevirapine in women with HIV-1 subtypes A, C, and D. J Acquir Immune Defic Syndr (2006) 1.94

Identification of nevirapine-resistant HIV-1 in the latent reservoir after single-dose nevirapine to prevent mother-to-child transmission of HIV-1. J Infect Dis (2009) 1.93

Factors associated with delayed initiation of HIV medical care among infected persons attending a southern HIV/AIDS clinic. South Med J (2006) 1.88

Simple adherence assessments to predict virologic failure among HIV-infected adults with discordant immunologic and clinical responses to antiretroviral therapy. AIDS Res Hum Retroviruses (2008) 1.84

HIV-1 tropism and survival in vertically infected Ugandan infants. J Infect Dis (2008) 1.83

Training programmes in global health. BMJ (2010) 1.83

An empirical approach to defining loss to follow-up among patients enrolled in antiretroviral treatment programs. Am J Epidemiol (2010) 1.81

Nurturing the global workforce in clinical research: the National Institutes of Health Fogarty International Clinical Scholars and Fellows Program. Am J Trop Med Hyg (2011) 1.81

Global development. Family planning and the Millennium Development Goals. Science (2010) 1.78

Undisclosed antiretroviral drug use in a multinational clinical trial (HIV Prevention Trials Network 052). J Infect Dis (2013) 1.77

Persistence of K103N-containing HIV-1 variants after single-dose nevirapine for prevention of HIV-1 mother-to-child transmission. J Infect Dis (2007) 1.73

Predictors of adherence to antiretroviral therapy in rural Zambia. J Acquir Immune Defic Syndr (2008) 1.73

Innate immune activation enhances hiv acquisition in women, diminishing the effectiveness of tenofovir microbicide gel. J Infect Dis (2012) 1.73

Vaginal douching: evidence for risks or benefits to women's health. Epidemiol Rev (2002) 1.71

Analysis of nevirapine (NVP) resistance in Ugandan infants who were HIV infected despite receiving single-Dose (SD) NVP versus SD NVP plus daily NVP up to 6 weeks of age to prevent HIV vertical transmission. J Infect Dis (2008) 1.70

High prevalence of HIV and syphilis in a remote native community of the Peruvian Amazon. Am J Trop Med Hyg (2007) 1.70

Improving retention in the early infant diagnosis of HIV program in rural Mozambique by better service integration. J Acquir Immune Defic Syndr (2011) 1.68

Factors associated with incorrect identification of recent HIV infection using the BED capture immunoassay. AIDS Res Hum Retroviruses (2011) 1.66

Prevalence and correlates of HIV and syphilis infections among men who have sex with men in seven provinces in China with historically low HIV prevalence. J Acquir Immune Defic Syndr (2010) 1.65

Nondisclosure of HIV status in a clinical trial setting: antiretroviral drug screening can help distinguish between newly diagnosed and previously diagnosed HIV infection. Clin Infect Dis (2013) 1.64

Sociocultural and epidemiological aspects of HIV/AIDS in Mozambique. BMC Int Health Hum Rights (2010) 1.64

Seroadaptive practices: association with HIV acquisition among HIV-negative men who have sex with men. PLoS One (2012) 1.64

Monitoring and evaluation of programmes to prevent mother to child transmission of HIV in Africa. BMJ (2007) 1.63

Educational programs to enhance medical expertise in tropical diseases: the Gorgas Course experience 1996-2001. Am J Trop Med Hyg (2002) 1.60

Antiretroviral drug resistance, HIV-1 tropism, and HIV-1 subtype among men who have sex with men with recent HIV-1 infection. AIDS (2007) 1.60

Serosorting is associated with a decreased risk of HIV seroconversion in the EXPLORE Study Cohort. PLoS One (2010) 1.59

HIV acquisition among women from selected areas of the United States: a cohort study. Ann Intern Med (2013) 1.59

Analysis of nevirapine resistance in HIV-infected infants who received extended nevirapine or nevirapine/zidovudine prophylaxis. AIDS (2011) 1.59

Recent patterns in population-based HIV prevalence in Swaziland. PLoS One (2013) 1.58

Expansion of HIV/AIDS in China: lessons from Yunnan Province. Soc Sci Med (2006) 1.58

Effect of nevirapine toxicity on choice of perinatal HIV prevention strategies. Am J Public Health (2002) 1.56

Risk factors for syphilis and prevalence of HIV, hepatitis B and C among men who have sex with men in Beijing, China: implications for HIV prevention. AIDS Behav (2008) 1.55

Use of traditional medicine among pregnant women in Lusaka, Zambia. J Altern Complement Med (2007) 1.55

HIV voluntary counseling and testing among injection drug users in south China: a study of a non-government organization based program. AIDS Behav (2007) 1.55

Modified directly observed antiretroviral therapy compared with self-administered therapy in treatment-naive HIV-1-infected patients: a randomized trial. Arch Intern Med (2009) 1.54

Delayed access to HIV diagnosis and care: Special concerns for the Southern United States. AIDS Care (2006) 1.52

A randomized trial of 2 different 4-drug antiretroviral regimens versus a 3-drug regimen, in advanced human immunodeficiency virus disease. J Infect Dis (2003) 1.51

Cervical cancer prevention in low- and middle-income countries: feasible, affordable, essential. Cancer Prev Res (Phila) (2011) 1.50

Specificity of four laboratory approaches for cross-sectional HIV incidence determination: analysis of samples from adults with known nonrecent HIV infection from five African countries. AIDS Res Hum Retroviruses (2012) 1.50

Association of cord blood nevirapine concentration with reported timing of dose and HIV-1 transmission. AIDS (2006) 1.48

Evaluation of the editing process in human immunodeficiency virus type 1 genotyping. J Clin Microbiol (2003) 1.46

Use of a high resolution melting (HRM) assay to compare gag, pol, and env diversity in adults with different stages of HIV infection. PLoS One (2011) 1.46

Estimation of HIV incidence using multiple biomarkers. Am J Epidemiol (2013) 1.43

Partner notification for sexually transmitted infections in developing countries: a systematic review. BMC Public Health (2010) 1.42

Prevalence of HIV infection and predictors for syphilis infection among female sex workers in southern China. Southeast Asian J Trop Med Public Health (2009) 1.42