Published in BMC Biol on February 20, 2012
Engineering H5N1 avian influenza viruses to study human adaptation. Nature (2012) 1.74
Evolution and ecology of influenza A viruses. Microbiol Rev (1992) 39.99
Preparing for the next pandemic. N Engl J Med (2005) 4.65
Laboratory-associated infections and biosafety. Clin Microbiol Rev (1995) 2.30
Laboratory-acquired infections. Clin Infect Dis (2009) 1.26
TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection. Proc Natl Acad Sci U S A (2009) 3.70
Influenza and the challenge for immunology. Nat Immunol (2006) 3.24
Pause on avian flu transmission research. Science (2012) 2.24
Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion. J Clin Invest (2010) 1.92
Paired analysis of TCRα and TCRβ chains at the single-cell level in mice. J Clin Invest (2010) 1.87
Mucosal immune responses predict clinical outcomes during influenza infection independently of age and viral load. Am J Respir Crit Care Med (2014) 1.75
Lipidomic profiling of influenza infection identifies mediators that induce and resolve inflammation. Cell (2013) 1.69
The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus. Nat Immunol (2013) 1.66
Virus-specific CD8+ T cells in the liver: armed and ready to kill. J Immunol (2007) 1.58
Respiratory epithelial cells in innate immunity to influenza virus infection. Cell Tissue Res (2010) 1.57
Quantitative impact of thymic selection on Foxp3+ and Foxp3- subsets of self-peptide/MHC class II-specific CD4+ T cells. Proc Natl Acad Sci U S A (2011) 1.54
T cell receptor αβ diversity inversely correlates with pathogen-specific antibody levels in human cytomegalovirus infection. Sci Transl Med (2012) 1.53
Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection. Nat Immunol (2013) 1.47
NFkappaB negatively regulates interferon-induced gene expression and anti-influenza activity. J Biol Chem (2006) 1.38
Depletion of alveolar macrophages during influenza infection facilitates bacterial superinfections. J Immunol (2013) 1.34
Chromatin condensation via the condensin II complex is required for peripheral T-cell quiescence. EMBO J (2010) 1.32
Consequences of immunodominant epitope deletion for minor influenza virus-specific CD8+-T-cell responses. J Virol (2005) 1.28
Epitope-specific TCRbeta repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides. Proc Natl Acad Sci U S A (2008) 1.24
Immunity to seasonal and pandemic influenza A viruses. Microbes Infect (2011) 1.21
Neonatal CD8 T-cell hierarchy is distinct from adults and is influenced by intrinsic T cell properties in respiratory syncytial virus infected mice. PLoS Pathog (2011) 1.17
A multi-valent vaccine approach that elicits broad immunity within an influenza subtype. Vaccine (2009) 1.15
Functional implications of T cell receptor diversity. Curr Opin Immunol (2009) 1.13
T cell immunoglobulin and mucin protein-3 (Tim-3)/Galectin-9 interaction regulates influenza A virus-specific humoral and CD8 T-cell responses. Proc Natl Acad Sci U S A (2011) 1.07
Transmission studies resume for avian flu. Science (2013) 1.07
Protective efficacy of cross-reactive CD8+ T cells recognising mutant viral epitopes depends on peptide-MHC-I structural interactions and T cell activation threshold. PLoS Pathog (2010) 1.06
Screening monoclonal antibodies for cross-reactivity in the ferret model of influenza infection. J Immunol Methods (2008) 0.98
Contemporary seasonal influenza A (H1N1) virus infection primes for a more robust response to split inactivated pandemic influenza A (H1N1) Virus vaccination in ferrets. Clin Vaccine Immunol (2010) 0.98
HLA targeting efficiency correlates with human T-cell response magnitude and with mortality from influenza A infection. Proc Natl Acad Sci U S A (2013) 0.96
Compromised respiratory function in lethal influenza infection is characterized by the depletion of type I alveolar epithelial cells beyond threshold levels. Am J Physiol Lung Cell Mol Physiol (2013) 0.95
Development of dual PLD1/2 and PLD2 selective inhibitors from a common 1,3,8-Triazaspiro[4.5]decane Core: discovery of Ml298 and Ml299 that decrease invasive migration in U87-MG glioblastoma cells. J Med Chem (2013) 0.95
Differential host response, rather than early viral replication efficiency, correlates with pathogenicity caused by influenza viruses. PLoS One (2013) 0.91
Terminal deoxynucleotidyltransferase is required for the establishment of private virus-specific CD8+ TCR repertoires and facilitates optimal CTL responses. J Immunol (2008) 0.91
Characterization of innate responses to influenza virus infection in a novel lung type I epithelial cell model. J Gen Virol (2013) 0.91
T Cell receptor clonotype influences epitope hierarchy in the CD8+ T cell response to respiratory syncytial virus infection. J Biol Chem (2010) 0.91
Enhanced susceptibility of Ago1/3 double-null mice to influenza A virus infection. J Virol (2012) 0.89
Protective memory responses are modulated by priming events prior to challenge. J Virol (2009) 0.89
NKG2D signaling on CD8⁺ T cells represses T-bet and rescues CD4-unhelped CD8⁺ T cell memory recall but not effector responses. Nat Med (2012) 0.89
Highly pathological influenza A virus infection is associated with augmented expression of PD-1 by functionally compromised virus-specific CD8+ T cells. J Virol (2013) 0.86
Interrogating the relationship between naïve and immune antiviral T cell repertoires. Curr Opin Virol (2013) 0.85
Influenza epitope-specific CD8+ T cell avidity, but not cytokine polyfunctionality, can be determined by TCRβ clonotype. J Immunol (2010) 0.84
Dendritic cells activated by an anti-inflammatory agent induce CD4(+) T helper type 2 responses without impairing CD8(+) memory and effector cytotoxic T-lymphocyte responses. Immunology (2009) 0.83
Reproducible selection of high avidity CD8+ T-cell clones following secondary acute virus infection. Proc Natl Acad Sci U S A (2014) 0.83
The human side of influenza. J Leukoc Biol (2012) 0.83
Clonally related CD8+ T cells responsible for rapid population of both diffuse nasal-associated lymphoid tissue and lung after respiratory virus infection. J Immunol (2011) 0.82
The two faces of heterologous immunity: protection or immunopathology. J Leukoc Biol (2013) 0.80
Host detection and the stealthy phenotype in influenza virus infection. Curr Top Microbiol Immunol (2015) 0.80
Discovery of a highly selective PLD2 inhibitor (ML395): a new probe with improved physiochemical properties and broad-spectrum antiviral activity against influenza strains. ChemMedChem (2014) 0.80
Intranasal influenza infection of mice and methods to evaluate progression and outcome. Methods Mol Biol (2013) 0.77
New approaches in immunotherapy. Science (2010) 0.76
Non-random lymphocyte distribution among virus-infected cells of the respiratory tract. Viral Immunol (2013) 0.76
Immunity to influenza. Preventing infection and regulating disease. Am J Respir Crit Care Med (2015) 0.75
Helminth infections predispose mice to pneumococcal pneumonia but not to other pneumonic pathogens. Med Microbiol Immunol (2014) 0.75