Published in EMBO J on December 17, 2010
Condensins: universal organizers of chromosomes with diverse functions. Genes Dev (2012) 2.40
Cohesin: a catenase with separate entry and exit gates? Nat Cell Biol (2011) 2.11
Global regulation of promoter melting in naive lymphocytes. Cell (2013) 2.05
Library construction for next-generation sequencing: overviews and challenges. Biotechniques (2014) 1.20
IgM memory B cells: a mouse/human paradox. Cell Mol Life Sci (2012) 1.03
H4K20 methylation regulates quiescence and chromatin compaction. Mol Biol Cell (2013) 0.99
SCFSlimb ubiquitin ligase suppresses condensin II-mediated nuclear reorganization by degrading Cap-H2. J Cell Biol (2013) 0.96
Variability of inducible expression across the hematopoietic system of tetracycline transactivator transgenic mice. PLoS One (2013) 0.96
Overlapping and non-overlapping functions of condensins I and II in neural stem cell divisions. PLoS Genet (2014) 0.95
Condensin targets and reduces unwound DNA structures associated with transcription in mitotic chromosome condensation. Nat Commun (2015) 0.91
Condensin-mediated chromosome organization and gene regulation. Front Genet (2015) 0.90
Maintenance of interphase chromosome compaction and homolog pairing in Drosophila is regulated by the condensin cap-h2 and its partner Mrg15. Genetics (2013) 0.89
Interplay of H2A deubiquitinase 2A-DUB/Mysm1 and the p19(ARF)/p53 axis in hematopoiesis, early T-cell development and tissue differentiation. Cell Death Differ (2015) 0.88
Condensin II mutation causes T-cell lymphoma through tissue-specific genome instability. Genes Dev (2016) 0.88
Transcription factor networks directing the development, function, and evolution of innate lymphoid effectors. Annu Rev Immunol (2015) 0.87
The C. elegans dosage compensation complex mediates interphase X chromosome compaction. Epigenetics Chromatin (2014) 0.85
Chromatin compaction in terminally differentiated avian blood cells: the role of linker histone H5 and non-histone protein MENT. Chromosome Res (2011) 0.83
Drosophila casein kinase I alpha regulates homolog pairing and genome organization by modulating condensin II subunit Cap-H2 levels. PLoS Genet (2015) 0.82
Developmentally regulated linker histone H1c promotes heterochromatin condensation and mediates structural integrity of rod photoreceptors in mouse retina. J Biol Chem (2013) 0.82
Calcium mobilization is both required and sufficient for initiating chromatin decondensation during activation of peripheral T-cells. Mol Immunol (2014) 0.82
Condensins are Required for Maintenance of Nuclear Architecture. Cells (2014) 0.80
Mechanisms of T(reg) Suppression: Still a Long Way to Go. Front Immunol (2012) 0.80
Histone deacetylation critically determines T cell subset radiosensitivity. J Immunol (2014) 0.78
Developmental heterogeneity in DNA packaging patterns influences T-cell activation and transmigration. PLoS One (2012) 0.78
The loading of condensin in the context of chromatin. Curr Genet (2016) 0.77
A condensed view of chromatin during T cell development. EMBO J (2011) 0.77
Condensin II Regulates Interphase Chromatin Organization Through the Mrg-Binding Motif of Cap-H2. G3 (Bethesda) (2015) 0.76
Chromatin decondensation and T cell hyperresponsiveness in diabetes-associated hyperglycemia. J Immunol (2014) 0.76
Transcriptional reprogramming in cellular quiescence. RNA Biol (2017) 0.75
Context-dependent regulation of Th17-associated genes and IFNγ expression by the transcription factor NFAT5. Immunol Cell Biol (2016) 0.75
The Use of Flow Cytometry to Assess the State of Chromatin in T Cells. J Vis Exp (2015) 0.75
Drosophila Condensin II subunit Chromosome-associated protein D3 regulates cell fate determination through non-cell-autonomous signaling. Development (2016) 0.75
Structural maintenance of chromosome complexes and bone development: the beginning of a wonderful relationship? Bonekey Rep (2013) 0.75
Constrained release of lamina-associated enhancers and genes from the nuclear envelope during T-cell activation facilitates their association in chromosome compartments. Genome Res (2017) 0.75
Mutation of Arabidopsis SMC4 identifies condensin as a corepressor of pericentromeric transposons and conditionally expressed genes. Genes Dev (2017) 0.75
High-resolution profiling of histone methylations in the human genome. Cell (2007) 85.74
Chromatin modifications and their function. Cell (2007) 55.98
The role of chromatin during transcription. Cell (2007) 26.48
Combinatorial patterns of histone acetylations and methylations in the human genome. Nat Genet (2008) 18.28
Dynamic regulation of nucleosome positioning in the human genome. Cell (2008) 15.60
MethPrimer: designing primers for methylation PCRs. Bioinformatics (2002) 14.48
Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells. Immunity (2009) 9.73
Nuclear organization of the genome and the potential for gene regulation. Nature (2007) 8.22
Homeostasis of naive and memory T cells. Immunity (2008) 7.48
Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment. Immunity (1995) 6.91
STATs: signal transducers and activators of transcription. Cell (1996) 6.10
Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses. Cell (1998) 5.92
Helper T cell differentiation is controlled by the cell cycle. Immunity (1998) 5.71
At the heart of the chromosome: SMC proteins in action. Nat Rev Mol Cell Biol (2006) 5.45
The JAK/STAT signaling pathway. J Cell Sci (2004) 4.23
Histone modification levels are predictive for gene expression. Proc Natl Acad Sci U S A (2010) 4.00
Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells. Immunity (1999) 3.53
The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L). Mol Cell Biol (2000) 3.34
SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality. Cell (1999) 3.15
The IL-2 receptor complex: its structure, function, and target genes. Annu Rev Immunol (1993) 2.96
The dynamics of chromosome organization and gene regulation. Annu Rev Biochem (2003) 2.71
Dynamic assembly of silent chromatin during thymocyte maturation. Nat Genet (2004) 2.68
Signaling through the hematopoietic cytokine receptors. Annu Rev Immunol (1995) 2.61
Condensin and cohesin: more than chromosome compactor and glue. Nat Rev Genet (2003) 2.56
Regulation of T lymphocyte metabolism. J Immunol (2004) 2.55
Th2 lineage commitment and efficient IL-4 production involves extended demethylation of the IL-4 gene. Immunity (2002) 2.47
Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation. Proc Natl Acad Sci U S A (1998) 2.26
Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells. Nat Immunol (2010) 2.19
Dynamic changes in histone-methylation 'marks' across the locus encoding interferon-gamma during the differentiation of T helper type 2 cells. Nat Immunol (2007) 2.13
Genome-wide analysis of histone methylation reveals chromatin state-based regulation of gene transcription and function of memory CD8+ T cells. Immunity (2009) 2.11
A temporal threshold for formaldehyde crosslinking and fixation. PLoS One (2009) 2.03
Erythropoietin induces activation of Stat5 through association with specific tyrosines on the receptor that are not required for a mitogenic response. Mol Cell Biol (1996) 1.86
Lifespans of naive, memory and effector lymphocytes. Curr Opin Immunol (1993) 1.82
Signals through gp130 upregulate bcl-x gene expression via STAT1-binding cis-element in cardiac myocytes. J Clin Invest (1997) 1.65
Building and breaking bridges between sister chromatids. Bioessays (2003) 1.61
Signaling from the IL-2 receptor to the nucleus. Cytokine Growth Factor Rev (1997) 1.60
Phosphatidylinositol-dependent actin filament binding by the SWI/SNF-like BAF chromatin remodeling complex. Proc Natl Acad Sci U S A (2002) 1.57
Suppressor of cytokine signaling-1 is a critical regulator of interleukin-7-dependent CD8+ T cell differentiation. Immunity (2003) 1.55
Histone hypomethylation is an indicator of epigenetic plasticity in quiescent lymphocytes. EMBO J (2004) 1.49
Induction of Bcl-x(L) expression by human T-cell leukemia virus type 1 Tax through NF-kappaB in apoptosis-resistant T-cell transfectants with Tax. J Virol (1999) 1.48
A kinetic and dynamic analysis of Foxp3 induced in T cells by TGF-beta. J Immunol (2007) 1.47
Identification of DNA methyltransferase 3a as a T cell receptor-induced regulator of Th1 and Th2 differentiation. J Immunol (2009) 1.45
Stat5 activation is uniquely associated with cytokine signaling in peripheral T cells. Immunity (1999) 1.40
DNA-dependent RNA polymerase levels during the response of human peripheral lymphocytes to phytohemagglutinin. Cell (1975) 1.39
The establishment and maintenance of lymphocyte identity through gene silencing. Nat Immunol (2003) 1.31
MTB, the murine homolog of condensin II subunit CAP-G2, represses transcription and promotes erythroid cell differentiation. Leukemia (2006) 1.28
T cell development: better living through chromatin. Nat Immunol (2007) 1.24
The Ets2 transcription factor inhibits apoptosis induced by colony-stimulating factor 1 deprivation of macrophages through a Bcl-xL-dependent mechanism. Mol Cell Biol (1999) 1.19
Two domains of the erythropoietin receptor are sufficient for Jak2 binding/activation and function. Mol Cell Biol (2006) 1.16
Epidermal growth factor receptor--mediated stat3 signaling blocks apoptosis in head and neck cancer. Laryngoscope (2000) 1.15
A mutation in a chromosome condensin II subunit, kleisin beta, specifically disrupts T cell development. Proc Natl Acad Sci U S A (2007) 1.11
Chromosome territory reorganization in a human disease with altered DNA methylation. Proc Natl Acad Sci U S A (2007) 1.06
Increased phosphorylation of eukaryotic initiation factor 4 alpha during early activation of T lymphocytes correlates with increased initiation factor 4F complex formation. Eur J Biochem (1993) 1.04
A role for STAT5A/B in protection of peripheral T-lymphocytes from postactivation apoptosis: insights from gene expression profiling. Cytokine (2006) 0.94
A novel nonhistone protein (MENT) promotes nuclear collapse at the terminal stage of avian erythropoiesis. Exp Cell Res (1992) 0.91
Defective T-cell function leading to reduced antibody production in a kleisin-beta mutant mouse. Immunology (2008) 0.81
Puma is an essential mediator of p53-dependent and -independent apoptotic pathways. Cancer Cell (2003) 7.60
TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection. Proc Natl Acad Sci U S A (2009) 3.70
SOCS3 regulates the plasticity of gp130 signaling. Nat Immunol (2003) 3.45
Influenza and the challenge for immunology. Nat Immunol (2006) 3.24
c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression. Genes Dev (2002) 3.16
Essential, nonredundant role for the phosphoinositide 3-kinase p110delta in signaling by the B-cell receptor complex. Mol Cell Biol (2002) 2.70
Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation. Cell (2009) 2.28
Stat5 tetramer formation is associated with leukemogenesis. Cancer Cell (2005) 2.26
Pause on avian flu transmission research. Science (2012) 2.24
Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons. Nature (2008) 2.10
Reduced lymphomyeloid repopulating activity from adult bone marrow and fetal liver of mice lacking expression of STAT5. Blood (2002) 1.96
Absence of an essential role for thymic stromal lymphopoietin receptor in murine B-cell development. Mol Cell Biol (2004) 1.96
Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion. J Clin Invest (2010) 1.92
Paired analysis of TCRα and TCRβ chains at the single-cell level in mice. J Clin Invest (2010) 1.87
Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2. Immunity (2004) 1.77
Mucosal immune responses predict clinical outcomes during influenza infection independently of age and viral load. Am J Respir Crit Care Med (2014) 1.75
Lipidomic profiling of influenza infection identifies mediators that induce and resolve inflammation. Cell (2013) 1.69
The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus. Nat Immunol (2013) 1.66
Virus-specific CD8+ T cells in the liver: armed and ready to kill. J Immunol (2007) 1.58
Respiratory epithelial cells in innate immunity to influenza virus infection. Cell Tissue Res (2010) 1.57
Absence of erythrogenesis and vasculogenesis in Plcg1-deficient mice. J Biol Chem (2001) 1.56
Quantitative impact of thymic selection on Foxp3+ and Foxp3- subsets of self-peptide/MHC class II-specific CD4+ T cells. Proc Natl Acad Sci U S A (2011) 1.54
T cell receptor αβ diversity inversely correlates with pathogen-specific antibody levels in human cytomegalovirus infection. Sci Transl Med (2012) 1.53
Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection. Nat Immunol (2013) 1.47
SOCS3: an essential regulator of LIF receptor signaling in trophoblast giant cell differentiation. EMBO J (2003) 1.47
The centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53-regulated apoptosis. EMBO J (2002) 1.38
NFkappaB negatively regulates interferon-induced gene expression and anti-influenza activity. J Biol Chem (2006) 1.38
Re-examination of the role of suppressor of cytokine signaling 1 (SOCS1) in the regulation of toll-like receptor signaling. J Biol Chem (2004) 1.35
Depletion of alveolar macrophages during influenza infection facilitates bacterial superinfections. J Immunol (2013) 1.34
Jak2 FERM domain interaction with the erythropoietin receptor regulates Jak2 kinase activity. Mol Cell Biol (2007) 1.34
Consequences of immunodominant epitope deletion for minor influenza virus-specific CD8+-T-cell responses. J Virol (2005) 1.28
Epitope-specific TCRbeta repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides. Proc Natl Acad Sci U S A (2008) 1.24
Immunity to seasonal and pandemic influenza A viruses. Microbes Infect (2011) 1.21
Neonatal CD8 T-cell hierarchy is distinct from adults and is influenced by intrinsic T cell properties in respiratory syncytial virus infected mice. PLoS Pathog (2011) 1.17
Two domains of the erythropoietin receptor are sufficient for Jak2 binding/activation and function. Mol Cell Biol (2006) 1.16
Regulation of progesterone levels during pregnancy and parturition by signal transducer and activator of transcription 5 and 20alpha-hydroxysteroid dehydrogenase. Mol Endocrinol (2004) 1.16
A multi-valent vaccine approach that elicits broad immunity within an influenza subtype. Vaccine (2009) 1.15
Functional implications of T cell receptor diversity. Curr Opin Immunol (2009) 1.13
Receptor specific downregulation of cytokine signaling by autophosphorylation in the FERM domain of Jak2. EMBO J (2006) 1.11
Identification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing protein. Mol Cell Biol (2002) 1.10
T cell immunoglobulin and mucin protein-3 (Tim-3)/Galectin-9 interaction regulates influenza A virus-specific humoral and CD8 T-cell responses. Proc Natl Acad Sci U S A (2011) 1.07
Transmission studies resume for avian flu. Science (2013) 1.07
Protective efficacy of cross-reactive CD8+ T cells recognising mutant viral epitopes depends on peptide-MHC-I structural interactions and T cell activation threshold. PLoS Pathog (2010) 1.06
Determination of the transphosphorylation sites of Jak2 kinase. Biochem Biophys Res Commun (2004) 1.03
Screening monoclonal antibodies for cross-reactivity in the ferret model of influenza infection. J Immunol Methods (2008) 0.98
Contemporary seasonal influenza A (H1N1) virus infection primes for a more robust response to split inactivated pandemic influenza A (H1N1) Virus vaccination in ferrets. Clin Vaccine Immunol (2010) 0.98
HLA targeting efficiency correlates with human T-cell response magnitude and with mortality from influenza A infection. Proc Natl Acad Sci U S A (2013) 0.96
Compromised respiratory function in lethal influenza infection is characterized by the depletion of type I alveolar epithelial cells beyond threshold levels. Am J Physiol Lung Cell Mol Physiol (2013) 0.95
Development of dual PLD1/2 and PLD2 selective inhibitors from a common 1,3,8-Triazaspiro[4.5]decane Core: discovery of Ml298 and Ml299 that decrease invasive migration in U87-MG glioblastoma cells. J Med Chem (2013) 0.95
A role for STAT5A/B in protection of peripheral T-lymphocytes from postactivation apoptosis: insights from gene expression profiling. Cytokine (2006) 0.94
Terminal deoxynucleotidyltransferase is required for the establishment of private virus-specific CD8+ TCR repertoires and facilitates optimal CTL responses. J Immunol (2008) 0.91
Characterization of innate responses to influenza virus infection in a novel lung type I epithelial cell model. J Gen Virol (2013) 0.91
Differential host response, rather than early viral replication efficiency, correlates with pathogenicity caused by influenza viruses. PLoS One (2013) 0.91
T Cell receptor clonotype influences epitope hierarchy in the CD8+ T cell response to respiratory syncytial virus infection. J Biol Chem (2010) 0.91
NKG2D signaling on CD8⁺ T cells represses T-bet and rescues CD4-unhelped CD8⁺ T cell memory recall but not effector responses. Nat Med (2012) 0.89
Enhanced susceptibility of Ago1/3 double-null mice to influenza A virus infection. J Virol (2012) 0.89
Protective memory responses are modulated by priming events prior to challenge. J Virol (2009) 0.89
JAK2, complemented by a second signal from c-kit or flt-3, triggers extensive self-renewal of primary multipotential hemopoietic cells. EMBO J (2002) 0.89
Negative regulation of Jak2 by its auto-phosphorylation at tyrosine 913 via the Epo signaling pathway. Cell Signal (2008) 0.89
The centrosomal, putative tumor suppressor protein TACC2 is dispensable for normal development, and deficiency does not lead to cancer. Mol Cell Biol (2004) 0.88
Leukemia inhibitory factor regulates trophoblast giant cell differentiation via Janus kinase 1-signal transducer and activator of transcription 3-suppressor of cytokine signaling 3 pathway. Mol Endocrinol (2008) 0.87
Characterization of a family of novel cysteine- serine-rich nuclear proteins (CSRNP). PLoS One (2007) 0.87
An early onset progressive motor neuron disorder in Scyl1-deficient mice is associated with mislocalization of TDP-43. J Neurosci (2012) 0.87
Jak1 deficiency leads to enhanced Abelson-induced B-cell tumor formation. Blood (2003) 0.87
DRAK2 regulates memory T cell responses following murine coronavirus infection. Autoimmunity (2007) 0.86
Role of erythropoietin receptor signaling in Friend virus-induced erythroblastosis and polycythemia. Blood (2005) 0.86
Highly pathological influenza A virus infection is associated with augmented expression of PD-1 by functionally compromised virus-specific CD8+ T cells. J Virol (2013) 0.86
Reduced CD18 levels drive regulatory T cell conversion into Th17 cells in the CD18hypo PL/J mouse model of psoriasis. J Immunol (2013) 0.86
Enhanced T cell apoptosis within Drak2-deficient mice promotes resistance to autoimmunity. J Immunol (2008) 0.86
Interrogating the relationship between naïve and immune antiviral T cell repertoires. Curr Opin Virol (2013) 0.85
Influenza epitope-specific CD8+ T cell avidity, but not cytokine polyfunctionality, can be determined by TCRβ clonotype. J Immunol (2010) 0.84
Evi-1 expression in Xenopus. Gene Expr Patterns (2005) 0.83
The human side of influenza. J Leukoc Biol (2012) 0.83
Dendritic cells activated by an anti-inflammatory agent induce CD4(+) T helper type 2 responses without impairing CD8(+) memory and effector cytotoxic T-lymphocyte responses. Immunology (2009) 0.83
Reproducible selection of high avidity CD8+ T-cell clones following secondary acute virus infection. Proc Natl Acad Sci U S A (2014) 0.83
Trophoblast stem cells rescue placental defect in SOCS3-deficient mice. J Biol Chem (2006) 0.83
Clonally related CD8+ T cells responsible for rapid population of both diffuse nasal-associated lymphoid tissue and lung after respiratory virus infection. J Immunol (2011) 0.82
The two faces of heterologous immunity: protection or immunopathology. J Leukoc Biol (2013) 0.80
Discovery of a highly selective PLD2 inhibitor (ML395): a new probe with improved physiochemical properties and broad-spectrum antiviral activity against influenza strains. ChemMedChem (2014) 0.80
Host detection and the stealthy phenotype in influenza virus infection. Curr Top Microbiol Immunol (2015) 0.80
Intranasal influenza infection of mice and methods to evaluate progression and outcome. Methods Mol Biol (2013) 0.77
Dangerous for ferrets: lethal for humans? BMC Biol (2012) 0.77
Non-random lymphocyte distribution among virus-infected cells of the respiratory tract. Viral Immunol (2013) 0.76
New approaches in immunotherapy. Science (2010) 0.76
Immunity to influenza. Preventing infection and regulating disease. Am J Respir Crit Care Med (2015) 0.75
Helminth infections predispose mice to pneumococcal pneumonia but not to other pneumonic pathogens. Med Microbiol Immunol (2014) 0.75