Published in Proc Natl Acad Sci U S A on February 21, 2012
Phytomonas: trypanosomatids adapted to plant environments. PLoS Pathog (2015) 1.61
Mitochondrial ClpX Activates a Key Enzyme for Heme Biosynthesis and Erythropoiesis. Cell (2015) 1.00
The streamlined genome of Phytomonas spp. relative to human pathogenic kinetoplastids reveals a parasite tailored for plants. PLoS Genet (2014) 0.95
Make it, take it, or leave it: heme metabolism of parasites. PLoS Pathog (2013) 0.92
Trypanocidal action of bisphosphonium salts through a mitochondrial target in bloodstream form Trypanosoma brucei. Int J Parasitol Drugs Drug Resist (2015) 0.81
Distinct Prominent Roles for Enzymes of Plasmodium berghei Heme Biosynthesis in Sporozoite and Liver Stage Maturation. Infect Immun (2016) 0.79
A Narnavirus in the Trypanosomatid Protist Plant Pathogen Phytomonas serpens. Genome Announc (2016) 0.77
Giardia intestinalis incorporates heme into cytosolic cytochrome b₅. Eukaryot Cell (2013) 0.77
Light-induced depigmentation in planarians models the pathophysiology of acute porphyrias. Elife (2016) 0.76
Co-dependence between trypanosome nuclear lamina components in nuclear stability and control of gene expression. Nucleic Acids Res (2016) 0.76
Heme pathway evolution in kinetoplastid protists. BMC Evol Biol (2016) 0.75
Genome Sequence of Phytomonas françai, a Cassava (Manihot esculenta) Latex Parasite. Genome Announc (2017) 0.75
Evidence for loss of a partial flagellar glycolytic pathway during trypanosomatid evolution. PLoS One (2014) 0.75
Identification of a bacteria-like ferrochelatase in Strongyloides venezuelensis, an animal parasitic nematode. PLoS One (2013) 0.75
Evolution of the Tetrapyrrole Biosynthetic Pathway in Secondary Algae: Conservation, Redundancy and Replacement. PLoS One (2016) 0.75
A rapid method of total lipid extraction and purification. Can J Biochem Physiol (1959) 173.74
RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models. Bioinformatics (2006) 87.59
Recent developments in the MAFFT multiple sequence alignment program. Brief Bioinform (2008) 22.07
Draft genome of the filarial nematode parasite Brugia malayi. Science (2007) 5.28
The Alamar Blue assay to determine drug sensitivity of African trypanosomes (T.b. rhodesiense and T.b. gambiense) in vitro. Acta Trop (1997) 4.73
Diversity of structures and properties among catalases. Cell Mol Life Sci (2004) 3.92
New functions for the ancient globin family: bacterial responses to nitric oxide and nitrosative stress. Mol Microbiol (2000) 2.71
The many roles of cytochrome b5. Pharmacol Ther (2003) 2.69
Cytochromes P450 and metabolism of xenobiotics. Cell Mol Life Sci (2001) 2.54
A haptoglobin-hemoglobin receptor conveys innate immunity to Trypanosoma brucei in humans. Science (2008) 2.33
Energy metabolism of trypanosomatids: adaptation to available carbon sources. Mol Biochem Parasitol (2006) 2.21
Lack of heme synthesis in a free-living eukaryote. Proc Natl Acad Sci U S A (2005) 1.95
A whole genome view of prokaryotic haem biosynthesis. Microbiology (2002) 1.92
Sterol 14alpha-demethylase as a potential target for antitrypanosomal therapy: enzyme inhibition and parasite cell growth. Chem Biol (2007) 1.82
Diversity and reductive evolution of mitochondria among microbial eukaryotes. Philos Trans R Soc Lond B Biol Sci (2010) 1.58
A novel cytochrome b5-like domain is linked to the carboxyl terminus of the Saccharomyces cerevisiae delta-9 fatty acid desaturase. J Biol Chem (1995) 1.42
Bacterial sensors of oxygen. Curr Opin Microbiol (2009) 1.27
Heme biosynthesis in bacterium-protozoon symbioses: enzymic defects in host hemoflagellates and complemental role of their intracellular symbiotes. Proc Natl Acad Sci U S A (1975) 1.22
A yeast sterol auxotroph (erg25) is rescued by addition of azole antifungals and reduced levels of heme. Proc Natl Acad Sci U S A (1997) 1.13
Propidium iodide-based methods for monitoring drug action in the kinetoplastidae: comparison with the Alamar Blue assay. Anal Biochem (2008) 1.13
New insight into Phaeodactylum tricornutum fatty acid metabolism. Cloning and functional characterization of plastidial and microsomal delta12-fatty acid desaturases. Plant Physiol (2003) 1.11
Evolution of the haem synthetic pathway in kinetoplastid flagellates: an essential pathway that is not essential after all? Int J Parasitol (2009) 1.11
Lipid metabolism in mucous-dwelling amitochondriate protozoa. Int J Parasitol (2002) 1.10
Naturally azole-resistant Leishmania braziliensis promastigotes are rendered susceptible in the presence of terbinafine: comparative study with azole-susceptible Leishmania mexicana promastigotes. Antimicrob Agents Chemother (1996) 1.09
A putative novel nuclear-encoded subunit of the cytochrome c oxidase complex in trypanosomatids. Mol Biochem Parasitol (2002) 1.08
Downregulation of the nuclear-encoded subunits of the complexes III and IV disrupts their respective complexes but not complex I in procyclic Trypanosoma brucei. Mol Microbiol (2005) 1.07
Bacterial heme biosynthesis and its biotechnological application. Appl Microbiol Biotechnol (2003) 1.07
Heme and menaquinone induced electron transport in lactic acid bacteria. Microb Cell Fact (2009) 1.06
LFR1 ferric iron reductase of Leishmania amazonensis is essential for the generation of infective parasite forms. J Biol Chem (2011) 1.05
A missing metabolic pathway in the cattle tick Boophilus microplus. Curr Biol (1999) 1.03
Biosynthesis of polyunsaturated fatty acids in lower eukaryotes. IUBMB Life (2006) 1.01
Functional characterization of front-end desaturases from trypanosomatids depicts the first polyunsaturated fatty acid biosynthetic pathway from a parasitic protozoan. FEBS J (2006) 1.00
Mechanistic analysis of a multiple product sterol methyltransferase implicated in ergosterol biosynthesis in Trypanosoma brucei. J Biol Chem (2006) 1.00
Heme requirement and intracellular trafficking in Trypanosoma cruzi epimastigotes. Biochem Biophys Res Commun (2007) 1.00
Using heme as an energy boost for lactic acid bacteria. Curr Opin Biotechnol (2011) 1.00
Stress response pathways in protozoan parasites. Cell Microbiol (2008) 0.99
Escherichia coli succinate dehydrogenase variant lacking the heme b. Proc Natl Acad Sci U S A (2007) 0.97
Novel mitochondrial complex II isolated from Trypanosoma cruzi is composed of 12 peptides including a heterodimeric Ip subunit. J Biol Chem (2009) 0.94
Role of peroxidases in the compensation of cytosolic ascorbate peroxidase knockdown in rice plants under abiotic stress. Plant Cell Environ (2011) 0.94
The Saccharomyces cerevisiae succinate dehydrogenase does not require heme for ubiquinone reduction. Biochim Biophys Acta (2007) 0.94
Properties of rat liver microsomal stearoyl-coenzyme A desaturase. Biochem J (1977) 0.92
Reversible binding of heme to proteins in cellular signal transduction. Acc Chem Res (2006) 0.92
Mutations in the heme b-binding residue of SDHC inhibit assembly of respiratory chain complex II in mammalian cells. Mitochondrion (2009) 0.90
Aerobic and anaerobic glucose metabolism of Phytomonas sp. isolated from Euphorbia characias. Mol Biochem Parasitol (1994) 0.88
Plant sterol 14 alpha-demethylase affinity for azole fungicides. Biochem Biophys Res Commun (2001) 0.88
Characterization of carbohydrate metabolism and demonstration of glycosomes in a Phytomonas sp. isolated from Euphorbia characias. Mol Biochem Parasitol (1992) 0.87
Functional studies of an evolutionarily conserved, cytochrome b5 domain protein reveal a specific role in axonemal organisation and the general phenomenon of post-division axonemal growth in trypanosomes. Cell Motil Cytoskeleton (2009) 0.86
Susceptibility of iron-loaded Borrelia burgdorferi to killing by hydrogen peroxide and human polymorphonuclear leucocytes. FEMS Microbiol Lett (1991) 0.85
Characterization of the NADH:ubiquinone oxidoreductase (complex I) in the trypanosomatid Phytomonas serpens (Kinetoplastida). FEBS J (2007) 0.83
NADH-ubiquinone oxidoreductase activity in the kinetoplasts of the plant trypanosomatid Phytomonas serpens. Parasitol Res (2004) 0.83
A gene encoding the plant-like alternative oxidase is present in Phytomonas but absent in Leishmania spp. J Eukaryot Microbiol (1998) 0.81
Adaptation of a cholesterol deficient human T cell line to growth with lanosterol. Biochem Biophys Res Commun (1994) 0.81
The absence of genes for cytochrome c oxidase and reductase subunits in maxicircle kinetoplast DNA of the respiration-deficient plant trypanosomatid Phytomonas serpens. Curr Genet (2000) 0.81
Revealing the complementation of ferredoxin by cytochrome b (5) in the Spirulina- (6)-desaturation reaction by N-terminal fusion and co-expression of the fungal-cytochrome b (5) domain and Spirulina- (6)-acyl-lipid desaturase. Appl Microbiol Biotechnol (2006) 0.81
The revised classification of eukaryotes. J Eukaryot Microbiol (2012) 3.48
Pseudogenes: are they "junk" or functional DNA? Annu Rev Genet (2003) 3.47
A photosynthetic alveolate closely related to apicomplexan parasites. Nature (2008) 2.91
Dating the tree of life. Science (2003) 2.76
The origin of malignant malaria. Proc Natl Acad Sci U S A (2009) 2.67
African great apes are natural hosts of multiple related malaria species, including Plasmodium falciparum. Proc Natl Acad Sci U S A (2010) 2.60
Evolutionary and geographical history of the Leishmania donovani complex with a revision of current taxonomy. Proc Natl Acad Sci U S A (2007) 2.41
A common red algal origin of the apicomplexan, dinoflagellate, and heterokont plastids. Proc Natl Acad Sci U S A (2010) 2.41
African apes as reservoirs of Plasmodium falciparum and the origin and diversification of the Laverania subgenus. Proc Natl Acad Sci U S A (2010) 2.31
Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs. Nature (2012) 2.15
Evolution and metabolic significance of the urea cycle in photosynthetic diatoms. Nature (2011) 2.06
The clonal theory of parasitic protozoa: 12 years on. Trends Parasitol (2002) 1.88
CBOL protist working group: barcoding eukaryotic richness beyond the animal, plant, and fungal kingdoms. PLoS Biol (2012) 1.84
Origins and evolution of spliceosomal introns. Annu Rev Genet (2006) 1.62
African monkeys are infected by Plasmodium falciparum nonhuman primate-specific strains. Proc Natl Acad Sci U S A (2011) 1.56
Adaptations of Trypanosoma brucei to gradual loss of kinetoplast DNA: Trypanosoma equiperdum and Trypanosoma evansi are petite mutants of T. brucei. Proc Natl Acad Sci U S A (2008) 1.51
Assembling and maintaining the Photosystem II complex in chloroplasts and cyanobacteria. Curr Opin Plant Biol (2012) 1.42
Population genetic structure of Plasmodium falciparum in the two main African vectors, Anopheles gambiae and Anopheles funestus. Proc Natl Acad Sci U S A (2007) 1.40
Response to Rougeron et al.: Leishmania population genetics: clonality, selfing and aneuploidy. Trends Parasitol (2015) 1.39
Microsporidia and 'the art of living together'. Adv Parasitol (2013) 1.38
Population genetics of Trypanosoma brucei gambiense, the agent of sleeping sickness in Western Africa. Proc Natl Acad Sci U S A (2008) 1.36
A methodological bias toward overestimation of molecular evolutionary time scales. Proc Natl Acad Sci U S A (2002) 1.36
Psb28 protein is involved in the biogenesis of the photosystem II inner antenna CP47 (PsbB) in the cyanobacterium Synechocystis sp. PCC 6803. Plant Physiol (2008) 1.29
Extreme inbreeding in Leishmania braziliensis. Proc Natl Acad Sci U S A (2009) 1.29
Sex-related similarities and differences in the neural correlates of beauty. Proc Natl Acad Sci U S A (2009) 1.27
Reproductive clonality of pathogens: a perspective on pathogenic viruses, bacteria, fungi, and parasitic protozoa. Proc Natl Acad Sci U S A (2012) 1.26
Unresolved direction of host transfer of Plasmodium vivax v. P. simium and P. malariae v. P. brasilianum. Infect Genet Evol (2010) 1.22
Evolutionary origins and functions of the carotenoid biosynthetic pathway in marine diatoms. PLoS One (2008) 1.21
Convergent neofunctionalization by positive Darwinian selection after ancient recurrent duplications of the xanthine dehydrogenase gene. Proc Natl Acad Sci U S A (2003) 1.17
Dual core processing: MRB1 is an emerging kinetoplast RNA editing complex. Trends Parasitol (2013) 1.17
A new Drosophila spliceosomal intron position is common in plants. Proc Natl Acad Sci U S A (2003) 1.15
Morphology, ultrastructure and life cycle of Vitrella brassicaformis n. sp., n. gen., a novel chromerid from the Great Barrier Reef. Protist (2011) 1.14
Diversity, host switching and evolution of Plasmodium vivax infecting African great apes. Proc Natl Acad Sci U S A (2013) 1.13
Molecular evolution of the Est-6 gene in Drosophila melanogaster: contrasting patterns of DNA variability in adjacent functional regions. Gene (2002) 1.13
A model for taxonomic work on homoxenous coccidia: redescription, host specificity, and molecular phylogeny of Eimeria ranae Dobell, 1909, with a review of anuran-host Eimeria (Apicomplexa: Eimeriorina). J Eukaryot Microbiol (2009) 1.12
Evolution of the haem synthetic pathway in kinetoplastid flagellates: an essential pathway that is not essential after all? Int J Parasitol (2009) 1.11
Progress in malaria research: the case for phylogenetics. Adv Parasitol (2003) 1.11
In the light of evolution VIII: Darwinian thinking in the social sciences. Introduction. Proc Natl Acad Sci U S A (2014) 1.09
Patterns of DNA sequence polymorphism at Sod vicinities in Drosophila melanogaster: unraveling the footprint of a recent selective sweep. Proc Natl Acad Sci U S A (2003) 1.07
Colloquium paper: in the light of evolution II: biodiversity and extinction. Proc Natl Acad Sci U S A (2008) 1.07
Morphology and ultrastructure of multiple life cycle stages of the photosynthetic relative of apicomplexa, Chromera velia. Protist (2011) 1.06
Science, evolution, and creationism. Proc Natl Acad Sci U S A (2008) 1.06
Multiple independent introductions of Plasmodium falciparum in South America. Proc Natl Acad Sci U S A (2011) 1.06
How clonal are Trypanosoma and Leishmania? Trends Parasitol (2013) 1.05
Re-evaluating the green versus red signal in eukaryotes with secondary plastid of red algal origin. Genome Biol Evol (2012) 1.05
Knock-downs of iron-sulfur cluster assembly proteins IscS and IscU down-regulate the active mitochondrion of procyclic Trypanosoma brucei. J Biol Chem (2006) 1.05
DNA variation and symbiotic associations in phenotypically diverse sea urchin Strongylocentrotus intermedius. Proc Natl Acad Sci U S A (2008) 1.05
The Psb27 assembly factor binds to the CP43 complex of photosystem II in the cyanobacterium Synechocystis sp. PCC 6803. Plant Physiol (2011) 1.04
Evolution of Fe/S cluster biogenesis in the anaerobic parasite Blastocystis. Proc Natl Acad Sci U S A (2012) 1.04
Pseudogene-derived small interference RNAs regulate gene expression in African Trypanosoma brucei. Proc Natl Acad Sci U S A (2011) 1.04
Diversity and phylogeny of insect trypanosomatids: all that is hidden shall be revealed. Trends Parasitol (2012) 1.02
From the Academy: Colloquium Perspective: In the light of evolution I: Adaptation and complex design. Proc Natl Acad Sci U S A (2007) 1.02
Plasmodium vivax: recent world expansion and genetic identity to Plasmodium simium. Proc Natl Acad Sci U S A (2005) 1.02
Genera of the human lineage. Proc Natl Acad Sci U S A (2003) 1.00
Alternative splicing: a missing piece in the puzzle of intron gain. Proc Natl Acad Sci U S A (2008) 1.00
Trypanosoma brucei: two steps to spread out from Africa. Trends Parasitol (2010) 0.99
Differences in iNOS and arginase expression and activity in the macrophages of rats are responsible for the resistance against T. gondii infection. PLoS One (2012) 0.99
In the light of evolution III: two centuries of Darwin. Proc Natl Acad Sci U S A (2009) 0.98
Functional characterization of two paralogs that are novel RNA binding proteins influencing mitochondrial transcripts of Trypanosoma brucei. RNA (2012) 0.97
Conserved chloroplast open-reading frame ycf54 is required for activity of the magnesium protoporphyrin monomethylester oxidative cyclase in Synechocystis PCC 6803. J Biol Chem (2012) 0.96
Trypanosomes and the solution to a 50-year mitochondrial calcium mystery. Trends Parasitol (2011) 0.96
DNA polymorphism in the beta-Esterase gene cluster of Drosophila melanogaster. Genetics (2003) 0.95
Is ectopic expression caused by deregulatory mutations or due to gene-regulation leaks with evolutionary potential? Bioessays (2005) 0.95
Discovery of a chlorophyll binding protein complex involved in the early steps of photosystem II assembly in Synechocystis. Plant Cell (2014) 0.94
A cyanobacterial chlorophyll synthase-HliD complex associates with the Ycf39 protein and the YidC/Alb3 insertase. Plant Cell (2014) 0.94
Long-term acclimation of the cyanobacterium Synechocystis sp. PCC 6803 to high light is accompanied by an enhanced production of chlorophyll that is preferentially channeled to trimeric photosystem I. Plant Physiol (2012) 0.93
Tetrapyrrole synthesis of photosynthetic chromerids is likely homologous to the unusual pathway of apicomplexan parasites. Plant Cell (2011) 0.93
Split photosystem protein, linear-mapping topology, and growth of structural complexity in the plastid genome of Chromera velia. Mol Biol Evol (2013) 0.92
Mitochondrial localization of human frataxin is necessary but processing is not for rescuing frataxin deficiency in Trypanosoma brucei. Proc Natl Acad Sci U S A (2008) 0.92
Make it, take it, or leave it: heme metabolism of parasites. PLoS Pathog (2013) 0.92
Clonal population structure and genetic diversity of Candida albicans in AIDS patients from Abidjan (Côte d'Ivoire). Proc Natl Acad Sci U S A (2006) 0.91
Evolution of cis-regulatory regions versus codifying regions. Int J Dev Biol (2003) 0.91
Detection of Plasmodium spp. in human feces. Emerg Infect Dis (2012) 0.90
Polymorphism patterns in two tightly linked developmental genes, Idgf1 and Idgf3, of Drosophila melanogaster. Genetics (2002) 0.89
The rise of model protozoa. Trends Microbiol (2012) 0.89
Phylogenetic character mapping of proteomic diversity shows high correlation with subspecific phylogenetic diversity in Trypanosoma cruzi. Proc Natl Acad Sci U S A (2010) 0.89
Paratrypanosoma is a novel early-branching trypanosomatid. Curr Biol (2013) 0.89
The assembly of F(1)F(O)-ATP synthase is disrupted upon interference of RNA editing in Trypanosoma brucei. Int J Parasitol (2009) 0.89
Cosmopolitan distribution of a trypanosomatid Leptomonas pyrrhocoris. Protist (2012) 0.89
Complex I (NADH:ubiquinone oxidoreductase) is active in but non-essential for procyclic Trypanosoma brucei. Mol Biochem Parasitol (2010) 0.89
The importance of the 45 S ribosomal small subunit-related complex for mitochondrial translation in Trypanosoma brucei. J Biol Chem (2013) 0.88
Colloquium paper: in the light of evolution IV: the human condition. Proc Natl Acad Sci U S A (2010) 0.88
Novel insights into the genetic diversity of Balantidium and Balantidium-like cyst-forming ciliates. PLoS Negl Trop Dis (2013) 0.88
Futile import of tRNAs and proteins into the mitochondrion of Trypanosoma brucei evansi. Mol Biochem Parasitol (2010) 0.88
Trypanosome Letm1 protein is essential for mitochondrial potassium homeostasis. J Biol Chem (2013) 0.88
Phylogenetic analysis of coccidian parasites from invertebrates: search for missing links. Protist (2006) 0.87
Growing diversity of trypanosomatid parasites of flies (Diptera: Brachycera): frequent cosmopolitism and moderate host specificity. Mol Phylogenet Evol (2013) 0.87
Pseudogenes are not pseudo any more. RNA Biol (2012) 0.87
Mitochondrial translation factors of Trypanosoma brucei: elongation factor-Tu has a unique subdomain that is essential for its function. Mol Microbiol (2013) 0.87
Distribution and origin of oxygen-dependent and oxygen-independent forms of Mg-protoporphyrin monomethylester cyclase among phototrophic proteobacteria. Appl Environ Microbiol (2013) 0.86
Models of spliceosomal intron proliferation in the face of widespread ectopic expression. Gene (2005) 0.86
Genome sequence of the marine photoheterotrophic bacterium Erythrobacter sp. strain NAP1. J Bacteriol (2011) 0.86
Comparative transcriptome analysis of small noncoding RNAs in different stages of Trypanosoma brucei. RNA (2013) 0.86