Published in Virol J on February 22, 2012
Toolbox for non-intrusive structural and functional analysis of recombinant VLP based vaccines: a case study with hepatitis B vaccine. PLoS One (2012) 1.04
Characterization of virus-like particles in GARDASIL® by cryo transmission electron microscopy. Hum Vaccin Immunother (2013) 0.94
Development of neutralizing monoclonal antibodies for oncogenic human papillomavirus types 31, 33, 45, 52, and 58. Clin Vaccine Immunol (2014) 0.88
Structural comparison of four different antibodies interacting with human papillomavirus 16 and mechanisms of neutralization. Virology (2015) 0.85
The development of a recombinant hepatitis E vaccine HEV 239. Hum Vaccin Immunother (2015) 0.84
In planta production of a candidate vaccine against bovine papillomavirus type 1. Planta (2012) 0.84
Lessons learned from successful human vaccines: Delineating key epitopes by dissecting the capsid proteins. Hum Vaccin Immunother (2015) 0.79
The U4 Antibody Epitope on Human Papillomavirus 16 Identified by Cryo-electron Microscopy. J Virol (2015) 0.78
Development of an IP-Free Biotechnology Platform for Constitutive Production of HPV16 L1 Capsid Protein Using the Pichia pastoris PGK1 Promoter. Biomed Res Int (2015) 0.78
Comparable quality attributes of hepatitis E vaccine antigen with and without adjuvant adsorption-dissolution treatment. Hum Vaccin Immunother (2015) 0.77
Safety of an Escherichia coli-expressed bivalent human papillomavirus (types 16 and 18) L1 virus-like particle vaccine: an open-label phase I clinical trial. Hum Vaccin Immunother (2013) 0.76
A human monoclonal antibody against HPV16 recognizes an immunodominant and neutralizing epitope partially overlapping with that of H16.V5. Sci Rep (2016) 0.76
My passion for biologics: from active sites to life-saving and public health. Hum Vaccin Immunother (2014) 0.75
Evidences of Changes in Surface Electrostatic Charge Distribution during Stabilization of HPV16 Virus-Like Particles. PLoS One (2016) 0.75
Coot: model-building tools for molecular graphics. Acta Crystallogr D Biol Crystallogr (2004) 227.01
Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallogr D Biol Crystallogr (1997) 137.43
Automated molecular microscopy: the new Leginon system. J Struct Biol (2005) 10.00
Measurements of the true affinity constant in solution of antigen-antibody complexes by enzyme-linked immunosorbent assay. J Immunol Methods (1985) 6.11
Simultaneous quantitation of antibodies to neutralizing epitopes on virus-like particles for human papillomavirus types 6, 11, 16, and 18 by a multiplexed luminex assay. Clin Diagn Lab Immunol (2003) 3.76
Maturation of papillomavirus capsids. J Virol (2005) 3.18
Surface conformational and linear epitopes on HPV-16 and HPV-18 L1 virus-like particles as defined by monoclonal antibodies. Virology (1996) 2.83
Polymorphism in the assembly of polyomavirus capsid protein VP1. Biophys J (1989) 2.74
Subunit interactions in bovine papillomavirus. Proc Natl Acad Sci U S A (2010) 2.51
Arrangement of L2 within the papillomavirus capsid. J Virol (2008) 2.37
Atomic model of the papillomavirus capsid. EMBO J (2002) 2.27
Virus-like particles in vaccine development. Expert Rev Vaccines (2010) 2.02
Crystal structures of four types of human papillomavirus L1 capsid proteins: understanding the specificity of neutralizing monoclonal antibodies. J Biol Chem (2007) 1.77
Quantitative disassembly and reassembly of human papillomavirus type 11 viruslike particles in vitro. J Virol (1998) 1.67
Characterization of a human papillomavirus type 16 variant-dependent neutralizing epitope. J Virol (1997) 1.66
HPV prophylactic vaccination: The first years and what to expect from now. Cancer Lett (2010) 1.65
Antibodies from women immunized with Gardasil cross-neutralize HPV 45 pseudovirions. Hum Vaccin (2007) 1.61
Papillomavirus assembly requires trimerization of the major capsid protein by disulfides between two highly conserved cysteines. J Virol (1998) 1.52
Hybrid papillomavirus L1 molecules assemble into virus-like particles that reconstitute conformational epitopes and induce neutralizing antibodies to distinct HPV types. Virology (2001) 1.52
Monoclonal antibodies to HPV-6 L1 virus-like particles identify conformational and linear neutralizing epitopes on HPV-11 in addition to type-specific epitopes on HPV-6. Virology (1996) 1.45
A monoclonal antibody against intact human papillomavirus type 16 capsids blocks the serological reactivity of most human sera. J Gen Virol (1997) 1.42
Reactivity pattern of 92 monoclonal antibodies with 15 human papillomavirus types. J Gen Virol (2008) 1.35
Identification of a human papillomavirus type 16-specific epitope on the C-terminal arm of the major capsid protein L1. J Virol (2003) 1.27
Developing an HPV vaccine to prevent cervical cancer and genital warts. Vaccine (2007) 1.21
Invariant polymorphism in virus capsid assembly. J Am Chem Soc (2009) 1.20
Disassembly and reassembly of yeast-derived recombinant human papillomavirus virus-like particles (HPV VLPs). J Pharm Sci (2006) 1.15
Prevention and treatment of papillomavirus-related cancers through immunization. Annu Rev Immunol (2011) 1.15
Structural basis of oligosaccharide receptor recognition by human papillomavirus. J Biol Chem (2010) 1.13
Identification of immunogenic regions of the major coat protein of human papillomavirus type 16 that contain type-restricted epitopes. J Gen Virol (1989) 1.11
GARDASIL: prophylactic human papillomavirus vaccine development--from bench top to bed-side. Clin Pharmacol Ther (2007) 1.10
Prevention of cancer through immunization: Prospects and challenges for the 21st century. Eur J Immunol (2007) 1.08
Mapping of linear epitopes of human papillomavirus type 16: the L1 and L2 open reading frames. Int J Cancer (1990) 1.07
Binding and neutralization efficiencies of monoclonal antibodies, Fab fragments, and scFv specific for L1 epitopes on the capsid of infectious HPV particles. Virology (2007) 1.07
Multiplexed serologic assay for nine anogenital human papillomavirus types. Clin Vaccine Immunol (2010) 1.05
Correlation between mouse potency and in vitro relative potency for human papillomavirus Type 16 virus-like particles and Gardasil vaccine samples. Hum Vaccin (2005) 1.01
Biochemical assessment of erythropoietin products from Asia versus US Epoetin alfa manufactured by Amgen. J Pharm Sci (2009) 0.96
The impact of a quadrivalent human papillomavirus (types 6, 11, 16, 18) virus-like particle vaccine in European women aged 16 to 24. J Eur Acad Dermatol Venereol (2009) 0.95
Disassembly and reassembly improves morphology and thermal stability of human papillomavirus type 16 virus-like particles. Nanomedicine (2012) 0.92
Prevention of cancer by prophylactic human papillomavirus vaccines. Curr Opin Immunol (2010) 0.92
Generalized structural polymorphism in self-assembled viral particles. Nano Lett (2008) 0.90
Mapping of human serum-reactive epitopes in virus-like particles of human papillomavirus types 16 and 11. Virology (2003) 0.89
Evaluation of the thermal stability of Gardasil. Hum Vaccin (2006) 0.87
Visualization of discrete L1 oligomers in human papillomavirus 16 virus-like particles by gel electrophoresis with Coomassie staining. J Virol Methods (2005) 0.87
Real time monitoring of antigenicity development of HBsAg virus-like particles (VLPs) during heat- and redox-treatment. Biochem Biophys Res Commun (2011) 0.85
In-depth process understanding of RECOMBIVAX HB® maturation and potential epitope improvements with redox treatment: multifaceted biochemical and immunochemical characterization. Vaccine (2011) 0.85
Determination of picomolar equilibrium dissociation constants in solution by enzyme-linked immunosorbent assay with fluorescence detection. Anal Biochem (2005) 0.83
Fine-structure epitope mapping of antierythropoietin monoclonal antibodies reveals a model of recombinant human erythropoietin structure. Blood (1996) 0.81
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science (2011) 13.16
Automated molecular microscopy: the new Leginon system. J Struct Biol (2005) 10.00
X-ray structure of a protein-conducting channel. Nature (2003) 9.20
Appion: an integrated, database-driven pipeline to facilitate EM image processing. J Struct Biol (2009) 5.71
Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment. Blood (2009) 5.21
Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer. Science (2013) 4.61
Outcome of the first electron microscopy validation task force meeting. Structure (2012) 4.35
Priming of naive T cells inside tumors leads to eradication of established tumors. Nat Immunol (2004) 3.95
The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor. Cell (2012) 3.91
Activity and connectivity of brain mood regulating circuit in depression: a functional magnetic resonance study. Biol Psychiatry (2005) 3.85
Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins. Proc Natl Acad Sci U S A (2008) 3.68
The therapeutic effect of anti-HER2/neu antibody depends on both innate and adaptive immunity. Cancer Cell (2010) 3.52
The structure of an infectious P22 virion shows the signal for headful DNA packaging. Science (2006) 3.33
A Staphylococcus aureus pore-forming toxin subverts the activity of ADAM10 to cause lethal infection in mice. Nat Med (2011) 3.17
Structural basis for cargo regulation of COPII coat assembly. Cell (2008) 3.15
Characterization of circulating endothelial cells in acute myocardial infarction. Sci Transl Med (2012) 2.91
Beam-induced motion of vitrified specimen on holey carbon film. J Struct Biol (2012) 2.84
Evidence that low-level viremias during effective highly active antiretroviral therapy result from two processes: expression of archival virus and replication of virus. J Virol (2005) 2.82
Movies of ice-embedded particles enhance resolution in electron cryo-microscopy. Structure (2012) 2.80
Optimization and validation of a multiplexed luminex assay to quantify antibodies to neutralizing epitopes on human papillomaviruses 6, 11, 16, and 18. Clin Diagn Lab Immunol (2005) 2.72
Structure of the Sec13/31 COPII coat cage. Nature (2006) 2.63
ACE: automated CTF estimation. Ultramicroscopy (2005) 2.62
Bacteriophage lambda stabilization by auxiliary protein gpD: timing, location, and mechanism of attachment determined by cryo-EM. Structure (2008) 2.62
Evolution, substrate specificity and subfamily classification of glycoside hydrolase family 5 (GH5). BMC Evol Biol (2012) 2.54
A previously unidentified alternatively spliced isoform of t(8;21) transcript promotes leukemogenesis. Nat Med (2006) 2.36
Neointimal hyperplasia in early arteriovenous fistula failure. Am J Kidney Dis (2007) 2.34
Multiple viral genetic analyses detect low-level human immunodeficiency virus type 1 replication during effective highly active antiretroviral therapy. J Virol (2003) 2.31
Local electronic properties of graphene on a BN substrate via scanning tunneling microscopy. Nano Lett (2011) 2.30
Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships. Gene (2003) 2.25
Crystal structure of west nile virus envelope glycoprotein reveals viral surface epitopes. J Virol (2006) 2.20
Prognostic value of coronary CT angiography and calcium score for major adverse cardiac events in outpatients. JACC Cardiovasc Imaging (2012) 2.17
Barriers to accessing TB diagnosis for rural-to-urban migrants with chronic cough in Chongqing, China: a mixed methods study. BMC Health Serv Res (2008) 2.17
Antidepressant effect on connectivity of the mood-regulating circuit: an FMRI study. Neuropsychopharmacology (2005) 2.16
Automated cryoEM data acquisition and analysis of 284742 particles of GroEL. J Struct Biol (2006) 2.15
Resting state corticolimbic connectivity abnormalities in unmedicated bipolar disorder and unipolar depression. Psychiatry Res (2009) 2.08
Cyclophilin A/Cluster of Differentiation 147 Interactions Participate in Early Brain Injury After Subarachnoid Hemorrhage in Rats. Crit Care Med (2015) 2.01
DNA methylation in inflammatory genes among children with obstructive sleep apnea. Am J Respir Crit Care Med (2011) 1.92
Organization of the influenza virus replication machinery. Science (2012) 1.89
Prophenoloxidase-activating proteinase-3 (PAP-3) from Manduca sexta hemolymph: a clip-domain serine proteinase regulated by serpin-1J and serine proteinase homologs. Insect Biochem Mol Biol (2003) 1.89
Peripheral nociception associated with surgical incision elicits remote nonischemic cardioprotection via neurogenic activation of protein kinase C signaling. Circulation (2009) 1.86
Nonproteolytic serine proteinase homologs are involved in prophenoloxidase activation in the tobacco hornworm, Manduca sexta. Insect Biochem Mol Biol (2003) 1.85
Visualizing ribosome biogenesis: parallel assembly pathways for the 30S subunit. Science (2010) 1.84
Fully automated, sequential tilt-series acquisition with Leginon. J Struct Biol (2009) 1.84
Automatic particle selection: results of a comparative study. J Struct Biol (2004) 1.82
Comprehensive detection and serotyping of human adenoviruses by PCR and sequencing. J Clin Microbiol (2004) 1.81
Lymphotoxin pathway directs thymic Aire expression. Nat Immunol (2003) 1.79
Management for postoperative complications of breast augmentation by injected polyacrylamide hydrogel. Aesthetic Plast Surg (2005) 1.78
The LRP5 high-bone-mass G171V mutation disrupts LRP5 interaction with Mesd. Mol Cell Biol (2004) 1.77
Initial evaluation of a direct detection device detector for single particle cryo-electron microscopy. J Struct Biol (2011) 1.77
Local expression of B7-H1 promotes organ-specific autoimmunity and transplant rejection. J Clin Invest (2004) 1.71
Antibacterial drug leads targeting isoprenoid biosynthesis. Proc Natl Acad Sci U S A (2012) 1.69
MicroRNA-127 modulates fetal lung development. Physiol Genomics (2009) 1.68
Malignant liver tumors: treatment with percutaneous microwave ablation--complications among cohort of 1136 patients. Radiology (2009) 1.68
Direct observation and adherence to tuberculosis treatment in Chongqing, China: a descriptive study. Health Policy Plan (2008) 1.68
The AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnover. Mol Biol Cell (2010) 1.65
CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion. EMBO J (2012) 1.65
Prophenoloxidase-activating proteinase-2 from hemolymph of Manduca sexta. A bacteria-inducible serine proteinase containing two clip domains. J Biol Chem (2002) 1.65
Antibodies from women immunized with Gardasil cross-neutralize HPV 45 pseudovirions. Hum Vaccin (2007) 1.61
Targeting the primary tumor to generate CTL for the effective eradication of spontaneous metastases. J Immunol (2007) 1.60
Novel cardioprotective role of a small heat-shock protein, Hsp20, against ischemia/reperfusion injury. Circulation (2005) 1.60
Patient-specific modeling and quantification of the aortic and mitral valves from 4-D cardiac CT and TEE. IEEE Trans Med Imaging (2010) 1.59
Presence and dissemination of the multiresistance gene cfr in Gram-positive and Gram-negative bacteria. J Antimicrob Chemother (2013) 1.59
Out of Tibet: Pliocene woolly rhino suggests high-plateau origin of Ice Age megaherbivores. Science (2011) 1.58
Anatomic configuration affects the flow rate and diameter of porcine arteriovenous fistulae. Kidney Int (2012) 1.58
Chemical vapour deposition growth of large single crystals of monolayer and bilayer graphene. Nat Commun (2013) 1.57
MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA. EMBO J (2012) 1.57
Hypertension prevalence, awareness, treatment, and control in 115 rural and urban communities involving 47 000 people from China. J Hypertens (2016) 1.57
ADAM10 mediates vascular injury induced by Staphylococcus aureus α-hemolysin. J Infect Dis (2012) 1.56
Efficient Constrained Local Model Fitting for Non-Rigid Face Alignment. Image Vis Comput (2009) 1.55
Manduca sexta serpin-3 regulates prophenoloxidase activation in response to infection by inhibiting prophenoloxidase-activating proteinases. J Biol Chem (2003) 1.55
Unnatural amino acid incorporation into virus-like particles. Bioconjug Chem (2008) 1.54
Severe venous neointimal hyperplasia prior to dialysis access surgery. Nephrol Dial Transplant (2011) 1.54
The molecular architecture of human Dicer. Nat Struct Mol Biol (2012) 1.53
Antibiotic-conjugated polyacrylate nanoparticles: new opportunities for development of anti-MRSA agents. Bioorg Med Chem Lett (2006) 1.53
Aberrant expression of TSC2 gene in the newly diagnosed acute leukemia. Leuk Res (2009) 1.52
Crystal structure of dengue virus type 1 envelope protein in the postfusion conformation and its implications for membrane fusion. J Virol (2009) 1.52
microRNA-143, down-regulated in osteosarcoma, promotes apoptosis and suppresses tumorigenicity by targeting Bcl-2. Oncol Rep (2010) 1.51
Allosteric regulation of DNA cleavage and sequence-specificity through run-on oligomerization. Structure (2013) 1.49
Effect of oral arginine supplementation on exhaled nitric oxide concentration in sickle cell anemia and acute chest syndrome. J Pediatr Hematol Oncol (2010) 1.49
Enhanced bioavailability of silymarin by self-microemulsifying drug delivery system. Eur J Pharm Biopharm (2006) 1.48
Photoinstability of S-nitrosothiols during sampling of whole blood: a likely source of error and variability in S-nitrosothiol measurements. Clin Chem (2008) 1.48