PubRank

A M Lesk

Author PubWeight™ 142.89‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Determinants of a protein fold. Unique features of the globin amino acid sequences. J Mol Biol 1987 18.58
2 The relation between the divergence of sequence and structure in proteins. EMBO J 1986 16.66
3 Canonical structures for the hypervariable regions of immunoglobulins. J Mol Biol 1987 6.42
4 How different amino acid sequences determine similar protein structures: the structure and evolutionary dynamics of the globins. J Mol Biol 1980 5.85
5 Interior and surface of monomeric proteins. J Mol Biol 1987 5.42
6 Structural mechanisms for domain movements in proteins. Biochemistry 1994 5.36
7 Conformations of immunoglobulin hypervariable regions. Nature 1990 5.31
8 The outline structure of the T-cell alpha beta receptor. EMBO J 1988 4.37
9 Phylogeny of the serpin superfamily: implications of patterns of amino acid conservation for structure and function. Genome Res 2000 3.55
10 Standard conformations for the canonical structures of immunoglobulins. J Mol Biol 1997 3.42
11 The accessible surface area and stability of oligomeric proteins. Nature 1987 2.77
12 Evolution of proteins formed by beta-sheets. II. The core of the immunoglobulin domains. J Mol Biol 1982 2.47
13 beta-Trefoil fold. Patterns of structure and sequence in the Kunitz inhibitors interleukins-1 beta and 1 alpha and fibroblast growth factors. J Mol Biol 1992 2.45
14 Correlation of co-ordinated amino acid substitutions with function in viruses related to tobacco mosaic virus. J Mol Biol 1987 2.28
15 Structural repertoire of the human VH segments. J Mol Biol 1992 2.06
16 Conformations of the third hypervariable region in the VH domain of immunoglobulins. J Mol Biol 1998 1.96
17 SH3 domains in prokaryotes. Trends Biochem Sci 1999 1.91
18 Evolution of proteins formed by beta-sheets. I. Plastocyanin and azurin. J Mol Biol 1982 1.76
19 The predicted structure of immunoglobulin D1.3 and its comparison with the crystal structure. Science 1986 1.68
20 Principles determining the structure of beta-sheet barrels in proteins. I. A theoretical analysis. J Mol Biol 1994 1.66
21 Computer-generated schematic diagrams of protein structures. Science 1982 1.57
22 Protein structural alignments and functional genomics. Proteins 2001 1.57
23 Domain closure in lactoferrin. Two hinges produce a see-saw motion between alternative close-packed interfaces. J Mol Biol 1993 1.55
24 Framework residue 71 is a major determinant of the position and conformation of the second hypervariable region in the VH domains of immunoglobulins. J Mol Biol 1990 1.53
25 Helix movements and the reconstruction of the haem pocket during the evolution of the cytochrome c family. J Mol Biol 1985 1.49
26 A method for multiple superposition of structures. Acta Crystallogr A 1992 1.48
27 Transmission of conformational change in insulin. Nature 1983 1.48
28 Folding units in globular proteins. Proc Natl Acad Sci U S A 1981 1.47
29 Domain closure in mitochondrial aspartate aminotransferase. J Mol Biol 1992 1.46
30 Principles determining the structure of beta-sheet barrels in proteins. II. The observed structures. J Mol Biol 1994 1.33
31 Common features of the conformations of antigen-binding loops in immunoglobulins and application to modeling loop conformations. Proteins 1992 1.29
32 The 2.6 A structure of antithrombin indicates a conformational change at the heparin binding site. J Mol Biol 1997 1.27
33 The structural repertoire of the human V kappa domain. EMBO J 1995 1.26
34 Mechanisms of domain closure in proteins. J Mol Biol 1984 1.22
35 Antibody modeling: implications for engineering and design. Methods 2000 1.18
36 The evolution of protein structures. Cold Spring Harb Symp Quant Biol 1987 1.17
37 Structural determinants of the conformations of medium-sized loops in proteins. Proteins 1989 1.15
38 An atlas of serpin conformations. Trends Biochem Sci 1998 1.13
39 Conformational changes in serpins: II. The mechanism of activation of antithrombin by heparin. J Mol Biol 2000 1.12
40 Antibody structure, prediction and redesign. Biophys Chem 1997 1.10
41 Importance of the release of strand 1C to the polymerization mechanism of inhibitory serpins. Protein Sci 1997 1.03
42 Computer-generated pictures of proteins. Methods Enzymol 1985 1.00
43 Conformational changes in serpins: I. The native and cleaved conformations of alpha(1)-antitrypsin. J Mol Biol 2000 1.00
44 Probing protein structure by solvent perturbation of nuclear magnetic resonance spectra. Nuclear magnetic resonance spectral editing and topological mapping in proteins by paramagnetic relaxation filtering. J Mol Biol 1992 1.00
45 Canonical structures for the hypervariable regions of T cell alphabeta receptors. J Mol Biol 2000 1.00
46 Fix L, a haemoglobin that acts as an oxygen sensor: signalling mechanism and structural basis of its homology with PAS domains. Chem Biol 1999 0.95
47 Solvent accessibility, protein surfaces, and protein folding. Biophys J 1980 0.92
48 Comparison of the structures of globins and phycocyanins: evidence for evolutionary relationship. Proteins 1990 0.92
49 Haemoglobin: the surface buried between the alpha 1 beta 1 and alpha 2 beta 2 dimers in the deoxy and oxy structures. J Mol Biol 1985 0.92
50 Conformational changes in serpins: I. The native and cleaved conformations of alpha(1)-antitrypsin. J Mol Biol 2000 0.90
51 Stabilization of the native tertiary stucture of yeast tRNALeu3 by cationic metal complexes. J Mol Biol 1975 0.90
52 Probing protein structure by solvent perturbation of NMR spectra: the surface accessibility of bovine pancreatic trypsin inhibitor. Biophys J 1997 0.89
53 Preparative induction and characterization of L-antithrombin: a structural homologue of latent plasminogen activator inhibitor-1. Biochemistry 1997 0.88
54 Modularity and homology: modelling of the titin type I modules and their interfaces. J Mol Biol 2001 0.87
55 Three-dimensional searching for recurrent structural motifs in data bases of protein structures. J Comput Biol 1994 0.85
56 Tendamistat surface accessibility to the TEMPOL paramagnetic probe. J Biomol NMR 1999 0.83
57 Serpins in the Caenorhabditis elegans genome. Proteins 1999 0.80
58 Modeling of serpin-protease complexes: antithrombin-thrombin, alpha 1-antitrypsin (358Met-->Arg)-thrombin, alpha 1-antitrypsin (358Met-->Arg)-trypsin, and antitrypsin-elastase. Proteins 1996 0.79
59 Probing protein structure by solvent perturbation of NMR spectra. II. Determination of surface and buried residues in homologous proteins. Biopolymers 1993 0.79
60 Why does DNA contain thymine and RNA uracil? J Theor Biol 1969 0.78
61 Macromolecular marionettes. Comput Biol Med 1977 0.78
62 Gathering them in to the fold. Nat Struct Biol 1996 0.77
63 Brave new proteins: what evolution reveals about protein structure. Curr Opin Biotechnol 1991 0.76
64 Structural alignment and analysis of two distantly related proteins: Aplysia limacina myoglobin and sea lamprey globin. Proteins 1988 0.76
65 Helix formation. Alarums and diversions. Nature 1991 0.75
66 A tale of two proteinases. Nat Struct Biol 1994 0.75
67 On hypothesized selective pressure by u.v. on DNA base compositions. J Theor Biol 1973 0.75
68 On the possibility of a stage in the evolution of the genetic message in which replication was imprecise. Biochem Biophys Res Commun 1970 0.75
69 Application of the common features of tranfer RNAs to the determination of their nucleotide sequences. Biochem Biophys Res Commun 1971 0.75
70 [Three-dimensional structures of proteins: archives, research and applications]. Tanpakushitsu Kakusan Koso 1986 0.75
71 An encoding technique to facilitate the detection of homologies in biopolymer sequences. J Theor Biol 1977 0.75
72 Transfer experiments: a plea for tolerance. Science 1968 0.75
73 A combinatorial study of the effects of admitting non-Watson-Crick base pairings and of base composition on the helix-forming potential of polynucleotides of random sequence. J Theor Biol 1974 0.75
74 [Protein structure, evolution, and conformational change]. Tanpakushitsu Kakusan Koso 1986 0.75
75 Molecular biology. Coordination of sequence data. Nature 1985 0.75
76 Spectroscopic features of nucleic acid evolution. Boll Chim Farm 1971 0.75