Enzymatic mechanisms regulating protein S-nitrosylation: implications in health and disease.

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STAT3 regulation by S-nitrosylation: implication for inflammatory disease. Antioxid Redox Signal (2014) 0.85

Redox mechanisms of cardiomyocyte mitochondrial protection. Front Physiol (2015) 0.85

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Protein S-nitrosylation: specificity and identification strategies in plants. Front Chem (2015) 0.80

Reversible S-nitrosylation in an engineered azurin. Nat Chem (2016) 0.80

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Identification of S-nitroso-CoA reductases that regulate protein S-nitrosylation. Proc Natl Acad Sci U S A (2014) 0.79

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Podocyte-specific VEGF-a gain of function induces nodular glomerulosclerosis in eNOS null mice. J Am Soc Nephrol (2014) 0.78

Nitrosative Stress, Hypernitrosylation, and Autoimmune Responses to Nitrosylated Proteins: New Pathways in Neuroprogressive Disorders Including Depression and Chronic Fatigue Syndrome. Mol Neurobiol (2016) 0.77

Response of the nitrergic system to activation of the neuroendocrine stress axis. Front Neurosci (2015) 0.77

S-nitrosation of glutathione transferase p1-1 is controlled by the conformation of a dynamic active site helix. J Biol Chem (2013) 0.77

Biological signaling by small inorganic molecules. Coord Chem Rev (2016) 0.77

Conversion of S-phenylsulfonylcysteine residues to mixed disulfides at pH 4.0: utility in protein thiol blocking and in protein-S-nitrosothiol detection. Org Biomol Chem (2014) 0.77

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Nitrosothiol formation and protection against Fenton chemistry by nitric oxide-induced dinitrosyliron complex formation from anoxia-initiated cellular chelatable iron increase. J Biol Chem (2014) 0.76

Hypoxia-induced changes in protein s-nitrosylation in female mouse brainstem. Am J Respir Cell Mol Biol (2015) 0.76

Glutathione and redox signaling in substance abuse. Biomed Pharmacother (2014) 0.76

Modulation of the conformational state of mitochondrial complex I as a target for therapeutic intervention. Interface Focus (2017) 0.76

Voluntary Exercise Can Ameliorate Insulin Resistance by Reducing iNOS-Mediated S-Nitrosylation of Akt in the Liver in Obese Rats. PLoS One (2015) 0.75

Quantitative Proteomics Analysis of VEGF-Responsive Endothelial Protein S-Nitrosylation Using Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) and LC-MS/MS. Biol Reprod (2016) 0.75

Nitrite as Direct S-Nitrosylating Agent of Kir2.1 Channels. Int Sch Res Notices (2014) 0.75

Nitrosopersulfide (SSNO(-)) decomposes in the presence of sulfide, cyanide or glutathione to give HSNO/SNO(-): consequences for the assumed role in cell signalling. Interface Focus (2017) 0.75

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Mechanism and catalytic strategy of the prokaryotic-specific GTP cyclohydrolase-IB. Biochem J (2017) 0.75

The role of nitric oxide in metabolic regulation of Dendritic cell immune function. Cancer Lett (2017) 0.75

Thioredoxin 1 regulation of protein S-desulfhydration. Biochem Biophys Rep (2015) 0.75

Protein S-nitrosylation: purview and parameters. Nat Rev Mol Cell Biol (2005) 10.65

S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding. Nat Cell Biol (2005) 7.25

IAP proteins: blocking the road to death's door. Nat Rev Mol Cell Biol (2002) 7.23

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S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function. Science (2004) 4.97

S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration. Nature (2006) 4.54

Regulated protein denitrosylation by cytosolic and mitochondrial thioredoxins. Science (2008) 4.51

A metabolic enzyme for S-nitrosothiol conserved from bacteria to humans. Nature (2001) 4.33

S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury. Science (2009) 4.25

S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death. Science (2002) 4.13

Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock. Cell (2004) 3.98

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Thioredoxin and related molecules--from biology to health and disease. Antioxid Redox Signal (2007) 3.50

Regulation of HIF-1alpha stability through S-nitrosylation. Mol Cell (2007) 3.50

Plant immunity requires conformational changes [corrected] of NPR1 via S-nitrosylation and thioredoxins. Science (2008) 3.43

Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle. Nat Med (2009) 3.27

RyR1 S-nitrosylation underlies environmental heat stroke and sudden death in Y522S RyR1 knockin mice. Cell (2008) 3.27

Chemical physiology of blood flow regulation by red blood cells: the role of nitric oxide and S-nitrosohemoglobin. Annu Rev Physiol (2005) 3.19

Protection from experimental asthma by an endogenous bronchodilator. Science (2005) 3.17

Reactions between nitric oxide and haemoglobin under physiological conditions. Nature (1998) 3.13

Inducible nitric oxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2. Science (2005) 3.05

S-nitrosylation in health and disease. Trends Mol Med (2003) 2.85

Hypercontractile female hearts exhibit increased S-nitrosylation of the L-type Ca2+ channel alpha1 subunit and reduced ischemia/reperfusion injury. Circ Res (2006) 2.84

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Proteomic analysis of S-nitrosylation and denitrosylation by resin-assisted capture. Nat Biotechnol (2009) 2.69

Regulation of beta-adrenergic receptor signaling by S-nitrosylation of G-protein-coupled receptor kinase 2. Cell (2007) 2.65

Endogenous nitrogen oxides and bronchodilator S-nitrosothiols in human airways. Proc Natl Acad Sci U S A (1993) 2.64

Thioredoxin catalyzes the S-nitrosation of the caspase-3 active site cysteine. Nat Chem Biol (2005) 2.60

Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity. Proc Natl Acad Sci U S A (2004) 2.55

Tumour maintenance is mediated by eNOS. Nature (2008) 2.52

Protein denitrosylation: enzymatic mechanisms and cellular functions. Nat Rev Mol Cell Biol (2009) 2.42

GAPDH mediates nitrosylation of nuclear proteins. Nat Cell Biol (2010) 2.22

Elevated levels of S-nitrosoalbumin in preeclampsia plasma. Circ Res (2001) 2.21

A central role for S-nitrosothiols in plant disease resistance. Proc Natl Acad Sci U S A (2005) 2.15

The diverse functions of GAPDH: views from different subcellular compartments. Cell Signal (2010) 2.15

Endogenous S-nitrosothiols protect against myocardial injury. Proc Natl Acad Sci U S A (2009) 2.13

S-nitrosylation from GSNOR deficiency impairs DNA repair and promotes hepatocarcinogenesis. Sci Transl Med (2010) 2.13

Higher blood flow and circulating NO products offset high-altitude hypoxia among Tibetans. Proc Natl Acad Sci U S A (2007) 2.07

Nitrosothiol reactivity profiling identifies S-nitrosylated proteins with unexpected stability. Chem Biol (2008) 1.94

S-nitrosation of the insulin receptor, insulin receptor substrate 1, and protein kinase B/Akt: a novel mechanism of insulin resistance. Diabetes (2005) 1.91

Hemoglobin conformation couples erythrocyte S-nitrosothiol content to O2 gradients. Proc Natl Acad Sci U S A (2005) 1.88

Structural profiling of endogenous S-nitrosocysteine residues reveals unique features that accommodate diverse mechanisms for protein S-nitrosylation. Proc Natl Acad Sci U S A (2010) 1.87

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S-Nitrosoglutathione is a substrate for rat alcohol dehydrogenase class III isoenzyme. Biochem J (1998) 1.83

Deficient ryanodine receptor S-nitrosylation increases sarcoplasmic reticulum calcium leak and arrhythmogenesis in cardiomyocytes. Proc Natl Acad Sci U S A (2007) 1.79

S-nitrosothiols signal hypoxia-mimetic vascular pathology. J Clin Invest (2007) 1.74

Impaired vasodilation by red blood cells in sickle cell disease. Proc Natl Acad Sci U S A (2005) 1.74

S-nitrosylation of peroxiredoxin 2 promotes oxidative stress-induced neuronal cell death in Parkinson's disease. Proc Natl Acad Sci U S A (2007) 1.73

S-nitrosoalbumin-mediated relaxation is enhanced by ascorbate and copper: effects in pregnancy and preeclampsia plasma. Hypertension (2004) 1.69

S-nitrosylation of NADPH oxidase regulates cell death in plant immunity. Nature (2011) 1.68

A nitric oxide processing defect of red blood cells created by hypoxia: deficiency of S-nitrosohemoglobin in pulmonary hypertension. Proc Natl Acad Sci U S A (2005) 1.67

S-nitrosylation of beta-arrestin regulates beta-adrenergic receptor trafficking. Mol Cell (2008) 1.63

Structural analysis of cysteine S-nitrosylation: a modified acid-based motif and the emerging role of trans-nitrosylation. J Mol Biol (2009) 1.62

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S-nitrosylation of surfactant protein-D controls inflammatory function. PLoS Biol (2008) 1.58

New insights into protein S-nitrosylation. Mitochondria as a model system. J Biol Chem (2004) 1.57

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Thioredoxin is required for S-nitrosation of procaspase-3 and the inhibition of apoptosis in Jurkat cells. Proc Natl Acad Sci U S A (2007) 1.52

Heme-assisted S-nitrosation of a proximal thiolate in a nitric oxide transport protein. Proc Natl Acad Sci U S A (2005) 1.52

Increased pasma S-nitrosothiol concentrations predict cardiovascular outcomes among patients with end-stage renal disease: a prospective study. J Am Soc Nephrol (2004) 1.51

Characterization of the S-denitrosation activity of protein disulfide isomerase. J Biol Chem (2004) 1.47

Modulation of nitrosative stress by S-nitrosoglutathione reductase is critical for thermotolerance and plant growth in Arabidopsis. Plant Cell (2008) 1.47

Thioredoxin and lipoic acid catalyze the denitrosation of low molecular weight and protein S-nitrosothiols. J Am Chem Soc (2005) 1.45

Transnitrosylation of XIAP regulates caspase-dependent neuronal cell death. Mol Cell (2010) 1.44

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Human carbonyl reductase 1 is an S-nitrosoglutathione reductase. J Biol Chem (2008) 1.40

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Acute physical exercise reverses S-nitrosation of the insulin receptor, insulin receptor substrate 1 and protein kinase B/Akt in diet-induced obese Wistar rats. J Physiol (2007) 1.38

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Compartmentalized connexin 43 s-nitrosylation/denitrosylation regulates heterocellular communication in the vessel wall. Arterioscler Thromb Vasc Biol (2010) 1.30

A protein microarray-based analysis of S-nitrosylation. Proc Natl Acad Sci U S A (2009) 1.29

A genetic analysis of nitrosative stress. Biochemistry (2009) 1.25

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S-Nitrosylation activates Cdk5 and contributes to synaptic spine loss induced by beta-amyloid peptide. Proc Natl Acad Sci U S A (2011) 1.21

Methionine adenosyltransferase S-nitrosylation is regulated by the basic and acidic amino acids surrounding the target thiol. J Biol Chem (1999) 1.21

S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease. Proc Natl Acad Sci U S A (2009) 1.20

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Identification of S-nitrosylated targets of thioredoxin using a quantitative proteomic approach. Biochemistry (2010) 1.23

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Cardioprotective effects of erythropoietin in the reperfused ischemic heart: a potential role for cardiac fibroblasts. J Biol Chem (2004) 1.20

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Host S-nitrosylation inhibits clostridial small molecule-activated glucosylating toxins. Nat Med (2011) 1.19

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Fiber type-specific nitric oxide protects oxidative myofibers against cachectic stimuli. PLoS One (2008) 1.10

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Aberrant S-nitrosylation mediates calcium-triggered ventricular arrhythmia in the intact heart. Proc Natl Acad Sci U S A (2012) 1.02

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