Aaron B Bowman

Author PubWeight™ 32.71‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1. Nature 2008 3.68
2 ATAXIN-1 interacts with the repressor Capicua in its native complex to cause SCA1 neuropathology. Cell 2006 3.39
3 Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2. Proc Natl Acad Sci U S A 2005 2.90
4 Glutamine-expanded ataxin-7 alters TFTC/STAGA recruitment and chromatin structure leading to photoreceptor dysfunction. PLoS Biol 2006 2.12
5 Ferroportin is a manganese-responsive protein that decreases manganese cytotoxicity and accumulation. J Neurochem 2009 1.23
6 ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarization. Dev Cell 2011 1.12
7 DMH1, a highly selective small molecule BMP inhibitor promotes neurogenesis of hiPSCs: comparison of PAX6 and SOX1 expression during neural induction. ACS Chem Neurosci 2012 1.11
8 Role of astrocytes in brain function and disease. Toxicol Pathol 2010 1.06
9 DHCEO accumulation is a critical mediator of pathophysiology in a Smith-Lemli-Opitz syndrome model. Neurobiol Dis 2011 1.05
10 Manganese Is Essential for Neuronal Health. Annu Rev Nutr 2015 1.03
11 Disease-toxicant screen reveals a neuroprotective interaction between Huntington's disease and manganese exposure. J Neurochem 2009 1.00
12 Disease-toxicant interactions in manganese exposed Huntington disease mice: early changes in striatal neuron morphology and dopamine metabolism. PLoS One 2012 0.92
13 Lipid modifications of Sonic hedgehog ligand dictate cellular reception and signal response. PLoS One 2011 0.91
14 Altered manganese homeostasis and manganese toxicity in a Huntington's disease striatal cell model are not explained by defects in the iron transport system. Toxicol Sci 2010 0.91
15 Genetic risk for Parkinson's disease correlates with alterations in neuronal manganese sensitivity between two human subjects. Neurotoxicology 2012 0.89
16 Gender and manganese exposure interactions on mouse striatal neuron morphology. Neurotoxicology 2011 0.88
17 Morphometric analysis in neurodegenerative disorders. Curr Protoc Toxicol 2010 0.88
18 Novel high-throughput assay to assess cellular manganese levels in a striatal cell line model of Huntington's disease confirms a deficit in manganese accumulation. Neurotoxicology 2011 0.87
19 Cellular fura-2 manganese extraction assay (CFMEA). Curr Protoc Toxicol 2011 0.84
20 The potential of induced pluripotent stem cells as a translational model for neurotoxicological risk. Neurotoxicology 2012 0.82
21 Age- and manganese-dependent modulation of dopaminergic phenotypes in a C. elegans DJ-1 genetic model of Parkinson's disease. Metallomics 2015 0.80
22 Changes in the striatal proteome of YAC128Q mice exhibit gene-environment interactions between mutant huntingtin and manganese. J Proteome Res 2012 0.80
23 Untargeted metabolic profiling identifies interactions between Huntington's disease and neuronal manganese status. Metallomics 2015 0.80
24 BDNF and Huntingtin protein modifications by manganese: implications for striatal medium spiny neuron pathology in manganese neurotoxicity. J Neurochem 2014 0.79
25 Optimization of fluorescence assay of cellular manganese status for high throughput screening. J Biochem Mol Toxicol 2012 0.79
26 Loss of pdr-1/parkin influences Mn homeostasis through altered ferroportin expression in C. elegans. Metallomics 2015 0.77
27 Novel BAC Mouse Model of Huntington's Disease with 225 CAG Repeats Exhibits an Early Widespread and Stable Degenerative Phenotype. J Huntingtons Dis 2015 0.76