Published in Biochim Biophys Acta on February 21, 2012
Identification and initial functional characterization of a human vascular cell-enriched long noncoding RNA. Arterioscler Thromb Vasc Biol (2014) 1.87
Human promoters are intrinsically directional. Mol Cell (2015) 1.31
Divergent transcription: a driving force for new gene origination? Cell (2013) 1.20
Genome-wide profiles of CtBP link metabolism with genome stability and epithelial reprogramming in breast cancer. Nat Commun (2013) 1.13
Genetic organization of interphase chromosome bands and interbands in Drosophila melanogaster. PLoS One (2014) 1.00
Regulation of Interferon-Stimulated Gene BST2 by a lncRNA Transcribed from a Shared Bidirectional Promoter. Front Immunol (2015) 0.90
Neighboring Genes Show Correlated Evolution in Gene Expression. Mol Biol Evol (2015) 0.89
A long non-coding RNA links calreticulin-mediated immunogenic cell removal to RB1 transcription. Oncogene (2015) 0.88
Bidirectional promoters in seed development and related hormone/stress responses. BMC Plant Biol (2013) 0.82
Regulatory dissection of the CBX5 and hnRNPA1 bi-directional promoter in human breast cancer cells reveals novel transcript variants differentially associated with HP1α down-regulation in metastatic cells. BMC Cancer (2016) 0.77
Beyond the histone tale: HP1α deregulation in breast cancer epigenetics. Cancer Biol Ther (2015) 0.77
A system for creating stable cell lines that express a gene of interest from a bidirectional and regulatable herpes simplex virus type 1 promoter. PLoS One (2015) 0.76
Suppression of expression between adjacent genes within heterologous modules in yeast. G3 (Bethesda) (2014) 0.76
Functional characterization of open chromatin in bidirectional promoters of rice. Sci Rep (2016) 0.76
Histone modifications facilitate the coexpression of bidirectional promoters in rice. BMC Genomics (2016) 0.76
The PRR11-SKA2 Bidirectional Transcription Unit Is Negatively Regulated by p53 through NF-Y in Lung Cancer Cells. Int J Mol Sci (2017) 0.75
Avian Leukosis Virus Activation of an Antisense RNA Upstream of TERT in B-Cell Lymphomas. J Virol (2016) 0.75
lncRNA-mediated regulation of the interferon response. Virus Res (2015) 0.75
Hallmarks of cancer: the next generation. Cell (2011) 140.01
High-resolution profiling of histone methylations in the human genome. Cell (2007) 85.74
Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature (2005) 31.60
A high-resolution map of active promoters in the human genome. Nature (2005) 24.35
MEME SUITE: tools for motif discovery and searching. Nucleic Acids Res (2009) 23.27
GoMiner: a resource for biological interpretation of genomic and proteomic data. Genome Biol (2003) 22.63
Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters. Science (2008) 16.48
Divergent transcription from active promoters. Science (2008) 11.03
DNA repair pathways as targets for cancer therapy. Nat Rev Cancer (2008) 6.69
Nascent transcript sequencing visualizes transcription at nucleotide resolution. Nature (2011) 5.95
An abundance of bidirectional promoters in the human genome. Genome Res (2004) 5.90
CtBP, an unconventional transcriptional corepressor in development and oncogenesis. Mol Cell (2002) 4.17
Bidirectional gene organization: a common architectural feature of the human genome. Cell (2002) 3.47
Structure, function and evolution of CpG island promoters. Cell Mol Life Sci (2003) 3.09
Divergent transcription: a new feature of active promoters. Cell Cycle (2009) 2.50
Transcription factor binding and modified histones in human bidirectional promoters. Genome Res (2007) 2.40
Systematic analysis of head-to-head gene organization: evolutionary conservation and potential biological relevance. PLoS Comput Biol (2006) 2.11
The transcriptional corepressor CtBP: a foe of multiple tumor suppressors. Cancer Res (2009) 2.02
The ets-related transcription factor GABP directs bidirectional transcription. PLoS Genet (2007) 1.67
Functional consequences of bidirectional promoters. Trends Genet (2011) 1.61
Roles of BRCA1 in DNA damage repair: a link between development and cancer. Hum Mol Genet (2003) 1.54
Isolation and characterisation of the NBR2 gene which lies head to head with the human BRCA1 gene. Hum Mol Genet (1997) 1.50
Comparative genomics of bidirectional gene pairs and its implications for the evolution of a transcriptional regulation system. Gene (2005) 1.26
Transcriptional regulation of BRCA1 expression by a metabolic switch. Nat Struct Mol Biol (2010) 1.25
A genome scale location analysis of human Staf/ZNF143-binding sites suggests a widespread role for human Staf/ZNF143 in mammalian promoters. J Biol Chem (2006) 1.17
Diversity of core promoter elements comprising human bidirectional promoters. BMC Genomics (2008) 1.10
Basal repression of BRCA1 by multiple E2Fs and pocket proteins at adjacent E2F sites. Cancer Biol Ther (2006) 1.09
Role of ZNF143 in tumor growth through transcriptional regulation of DNA replication and cell-cycle-associated genes. Cancer Sci (2010) 1.03
Genome-wide evidence for an essential role of the human Staf/ZNF143 transcription factor in bidirectional transcription. Nucleic Acids Res (2010) 0.97
CpG island methylation affects accessibility of the proximal BRCA1 promoter to transcription factors. Breast Cancer Res Treat (2009) 0.97
GA-binding protein alpha/beta is a critical regulator of the BRCA1 promoter. Oncogene (2000) 0.91
Regulation of the rat thyrotropin receptor gene by the methylation-sensitive transcription factor GA-binding protein. Mol Endocrinol (1998) 0.90
Genome wide study of NF-Y type CCAAT boxes in unidirectional and bidirectional promoters in human and mouse. J Theor Biol (2011) 0.81
Transcriptional regulation of bidirectional gene pairs by 17-β-estradiol in MCF-7 breast cancer cells. Braz J Med Biol Res (2010) 0.79
Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis. Mol Cell (2008) 3.32
Cyclin T1 overexpression induces malignant transformation and tumor growth. Cell Cycle (2010) 2.38
qPrimerDepot: a primer database for quantitative real time PCR. Nucleic Acids Res (2006) 2.31
SAP regulates T(H)2 differentiation and PKC-theta-mediated activation of NF-kappaB1. Immunity (2004) 2.18
The histone acetyltransferase MOF is a key regulator of the embryonic stem cell core transcriptional network. Cell Stem Cell (2012) 2.17
Active chromatin hub of the mouse alpha-globin locus forms in a transcription factory of clustered housekeeping genes. Mol Cell Biol (2006) 1.72
Dynamic bookmarking of primary response genes by p300 and RNA polymerase II complexes. Proc Natl Acad Sci U S A (2009) 1.31
In vitro combination characterization of the new anticancer plant drug beta-elemene with taxanes against human lung carcinoma. Int J Oncol (2007) 1.26
Transcriptional regulation of BRCA1 expression by a metabolic switch. Nat Struct Mol Biol (2010) 1.25
Genome-wide profiles of CtBP link metabolism with genome stability and epithelial reprogramming in breast cancer. Nat Commun (2013) 1.13
Regulation of endothelial thrombomodulin expression by inflammatory cytokines is mediated by activation of nuclear factor-kappa B. Blood (2005) 1.13
In support of the BMRB. Nat Struct Mol Biol (2012) 1.09
ELL facilitates RNA polymerase II pause site entry and release. Nat Commun (2012) 1.07
Selective leukemic-cell killing by a novel functional class of thalidomide analogs. Blood (2006) 1.06
Transcriptional autoregulation by BRCA1. Cancer Res (2010) 1.05
Kinetic profiles of p300 occupancy in vivo predict common features of promoter structure and coactivator recruitment. Proc Natl Acad Sci U S A (2004) 1.00
Wounds that will not heal: pervasive cellular reprogramming in cancer. Am J Pathol (2013) 0.96
Identification of new Rel/NFkappaB regulatory networks by focused genome location analysis. Cell Cycle (2009) 0.92
Inter-MAR association contributes to transcriptionally active looping events in human beta-globin gene cluster. PLoS One (2009) 0.90
Transcriptional networks inferred from molecular signatures of breast cancer. Am J Pathol (2008) 0.90
Dual regulation of soluble tumor necrosis factor-alpha induced activation of human monocytic cells via modulating transmembrane TNF-alpha-mediated 'reverse signaling'. Int J Mol Med (2006) 0.89
BRD4 short isoform interacts with RRP1B, SIPA1 and components of the LINC complex at the inner face of the nuclear membrane. PLoS One (2013) 0.88
BRCA1 loss induces GADD153-mediated doxorubicin resistance in prostate cancer. Mol Cancer Res (2011) 0.88
Transcription factor E2F-1 is upregulated in human gastric cancer tissues and its overexpression suppresses gastric tumor cell proliferation. Cell Oncol (2007) 0.87
Combinatorial antileukemic disruption of oxidative homeostasis and mitochondrial stability by the redox reactive thalidomide 2-(2,4-difluoro-phenyl)-4,5,6,7-tetrafluoro-1H-isoindole-1,3(2H)-dione (CPS49) and flavopiridol. Mol Pharmacol (2008) 0.87
Cross-regulation of T cell growth factor expression by p53 and the Tax oncogene. J Immunol (2002) 0.86
Evaluation of combination gene therapy with PTEN and antisense hTERT for malignant glioma in vitro and xenografts. Cell Mol Life Sci (2007) 0.85
Targeting combinatorial transcriptional complex assembly at specific modules within the interleukin-2 promoter by the immunosuppressant SB203580. J Biol Chem (2003) 0.85
C-Terminal Binding Protein: A Molecular Link between Metabolic Imbalance and Epigenetic Regulation in Breast Cancer. Int J Cell Biol (2013) 0.84
Complexity in built environment, health, and destination walking: a neighborhood-scale analysis. J Urban Health (2012) 0.83
The human WW45 protein enhances MST1-mediated apoptosis in vivo. Int J Mol Med (2009) 0.83
Comparison of properties of traditional and accelerated carbonated solidified/stabilized contaminated soils. J Environ Sci (China) (2008) 0.82
Functional profiling of uncommon VCAM1 promoter polymorphisms prevalent in African American populations. Hum Mutat (2007) 0.81
Multimembrane dot-blotting: a cost-effective tool for proteome analysis. Biotechniques (2004) 0.79
Timing of apoptosis onset depends on cell cycle progression in peripheral blood lymphocytes and lymphocytic leukemia cells. Oncol Rep (2007) 0.79
HER2-specific T lymphocytes kill both trastuzumab-resistant and trastuzumab-sensitive breast cell lines in vitro. Chin J Cancer Res (2012) 0.78
Human promoter genomic composition demonstrates non-random groupings that reflect general cellular function. BMC Bioinformatics (2005) 0.78
Wnt/β-Catenin mediates AICAR effect to increase GATA3 expression and inhibit adipogenesis. J Biol Chem (2015) 0.78
[Efficacy of gemcitabine-based chemotherapy on advanced pancreatic cancer]. Ai Zheng (2007) 0.77
Profiling the expression of mitogen-induced T-cell proteins by using multi-membrane dot-blotting. Biochem Biophys Res Commun (2004) 0.77
Dynamic coregulatory complex containing BRCA1, E2F1 and CtIP controls ATM transcription. Cell Physiol Biochem (2012) 0.77
Novel cell-specific and dominant negative anti-apoptotic roles of p73 in transformed leukemia cells. J Biol Chem (2002) 0.77
Mobilization of Peripheral Blood Stem Cells Using Regimen Combining Docetaxel with Granulocyte Colony-stimulating Factor in Breast Cancer Patients. Chin J Cancer Res (2011) 0.75
[Phase II clinical trial of oxaliplatin alone for refractory advanced colorectal cancer]. Ai Zheng (2003) 0.75
Low doses of CPS49 and flavopiridol combination as potential treatment for advanced prostate cancer. Curr Pharm Biotechnol (2015) 0.75
Application of multicriteria decision analysis tools to two contaminated sediment case studies. Integr Environ Assess Manag (2007) 0.75
Size-dependent enrichment of waste slag aggregate fragments abraded from asphalt concrete. J Hazard Mater (2011) 0.75