PubRank

Sean P Colgan

Author PubWeight™ 143.08‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J Exp Med 2002 7.99
2 Crucial role for ecto-5'-nucleotidase (CD73) in vascular leakage during hypoxia. J Exp Med 2004 4.16
3 Ecto-5'-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia. J Clin Invest 2002 4.05
4 Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis. J Clin Invest 2004 3.90
5 Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene. Cancer Res 2002 3.75
6 Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors. J Exp Med 2003 3.71
7 Resolvin D1 and its aspirin-triggered 17R epimer. Stereochemical assignments, anti-inflammatory properties, and enzymatic inactivation. J Biol Chem 2007 3.28
8 Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia. Nat Med 2012 3.03
9 Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes. J Immunol 2006 3.03
10 Mucosal protection by hypoxia-inducible factor prolyl hydroxylase inhibition. Gastroenterology 2008 2.99
11 Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: coordination by extracellular nucleotide metabolism. Blood 2004 2.80
12 HIF-dependent induction of adenosine A2B receptor in hypoxia. FASEB J 2006 2.46
13 HIF-1-dependent repression of equilibrative nucleoside transporter (ENT) in hypoxia. J Exp Med 2005 2.35
14 ATP release from activated neutrophils occurs via connexin 43 and modulates adenosine-dependent endothelial cell function. Circ Res 2006 2.23
15 Reduced inflammation and tissue damage in transgenic rabbits overexpressing 15-lipoxygenase and endogenous anti-inflammatory lipid mediators. J Immunol 2003 2.23
16 CD1d-dependent macrophage-mediated clearance of Pseudomonas aeruginosa from lung. Nat Med 2002 2.22
17 Hypoxia and gastrointestinal disease. J Mol Med (Berl) 2007 2.06
18 Lipid mediator-induced expression of bactericidal/ permeability-increasing protein (BPI) in human mucosal epithelia. Proc Natl Acad Sci U S A 2002 2.01
19 Transepithelial migration of neutrophils: mechanisms and implications for acute lung injury. Am J Respir Cell Mol Biol 2008 1.93
20 Role of vasodilator-stimulated phosphoprotein in PKA-induced changes in endothelial junctional permeability. FASEB J 2002 1.90
21 NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis. Inflamm Bowel Dis 2010 1.84
22 Central role of Sp1-regulated CD39 in hypoxia/ischemia protection. Blood 2008 1.79
23 Defective leukocyte GM-CSF receptor (CD116) expression and function in inflammatory bowel disease. Gastroenterology 2011 1.73
24 Signaling through the A2B adenosine receptor dampens endotoxin-induced acute lung injury. J Immunol 2010 1.70
25 Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa. Proc Natl Acad Sci U S A 2012 1.70
26 Contribution of adenosine A2B receptors to inflammatory parameters of experimental colitis. J Immunol 2009 1.68
27 Elevated ecto-5'-nucleotidase-mediated increased renal adenosine signaling via A2B adenosine receptor contributes to chronic hypertension. Circ Res 2013 1.68
28 Resolvin E1 promotes mucosal surface clearance of neutrophils: a new paradigm for inflammatory resolution. FASEB J 2007 1.67
29 Endothelial catabolism of extracellular adenosine during hypoxia: the role of surface adenosine deaminase and CD26. Blood 2006 1.65
30 Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction of beta2 integrin gene expression. Proc Natl Acad Sci U S A 2004 1.56
31 Small ubiquitin-related modifier-1 modification mediates resolution of CREB-dependent responses to hypoxia. Proc Natl Acad Sci U S A 2003 1.52
32 Inflammatory hypoxia: role of hypoxia-inducible factor. Cell Cycle 2005 1.50
33 CD1d function is regulated by microsomal triglyceride transfer protein. Nat Med 2004 1.49
34 Antiinflammatory adaptation to hypoxia through adenosine-mediated cullin-1 deneddylation. J Clin Invest 2007 1.47
35 Delineation of a CD1d-restricted antigen presentation pathway associated with human and mouse intestinal epithelial cells. Gastroenterology 2003 1.45
36 Metabolic shifts in immunity and inflammation. J Immunol 2010 1.45
37 Role of VASP in reestablishment of epithelial tight junction assembly after Ca2+ switch. Am J Physiol Cell Physiol 2002 1.43
38 Resolvin E1-induced intestinal alkaline phosphatase promotes resolution of inflammation through LPS detoxification. Proc Natl Acad Sci U S A 2010 1.39
39 Neutrophils as sources of extracellular nucleotides: functional consequences at the vascular interface. Trends Cardiovasc Med 2008 1.36
40 PMNs facilitate translocation of platelets across human and mouse epithelium and together alter fluid homeostasis via epithelial cell-expressed ecto-NTPDases. J Clin Invest 2008 1.35
41 Control of IFN-alphaA by CD73: implications for mucosal inflammation. J Immunol 2008 1.34
42 Neutrophil-derived glutamate regulates vascular endothelial barrier function. J Biol Chem 2002 1.30
43 Recognition of intestinal epithelial HIF-1alpha activation by Pseudomonas aeruginosa. Am J Physiol Gastrointest Liver Physiol 2006 1.30
44 Selective induction of mucin-3 by hypoxia in intestinal epithelia. J Cell Biochem 2006 1.30
45 Hypoxia-independent activation of HIF-1 by enterobacteriaceae and their siderophores. Gastroenterology 2007 1.29
46 HIF-dependent induction of apical CD55 coordinates epithelial clearance of neutrophils. FASEB J 2005 1.28
47 Hypoxia and metabolic factors that influence inflammatory bowel disease pathogenesis. Gastroenterology 2011 1.26
48 Neutrophil transmigration triggers repair of the lung epithelium via beta-catenin signaling. Proc Natl Acad Sci U S A 2011 1.25
49 Fractalkine-mediated signals regulate cell-survival and immune-modulatory responses in intestinal epithelial cells. Gastroenterology 2002 1.23
50 Selective induction of integrin beta1 by hypoxia-inducible factor: implications for wound healing. FASEB J 2008 1.17
51 Adenosine A2A receptor is a unique angiogenic target of HIF-2alpha in pulmonary endothelial cells. Proc Natl Acad Sci U S A 2009 1.12
52 A molecular defect in intracellular lipid signaling in human neutrophils in localized aggressive periodontal tissue damage. J Immunol 2004 1.12
53 Antiadhesive role of apical decay-accelerating factor (CD55) in human neutrophil transmigration across mucosal epithelia. J Exp Med 2003 1.11
54 Of microbes and meals: the health consequences of dietary endotoxemia. Nutr Clin Pract 2012 1.10
55 CD73+ regulatory T cells contribute to adenosine-mediated resolution of acute lung injury. FASEB J 2013 1.10
56 Identification of vasodilator-stimulated phosphoprotein (VASP) as an HIF-regulated tissue permeability factor during hypoxia. FASEB J 2007 1.08
57 Control of creatine metabolism by HIF is an endogenous mechanism of barrier regulation in colitis. Proc Natl Acad Sci U S A 2013 1.04
58 Hypoxia-inducible factor signaling provides protection in Clostridium difficile-induced intestinal injury. Gastroenterology 2010 1.04
59 Targeting the A2B adenosine receptor during gastrointestinal ischemia and inflammation. Expert Opin Ther Targets 2009 1.04
60 Hypoxia-inducible factor-dependent regulation of platelet-activating factor receptor as a route for gram-positive bacterial translocation across epithelia. Mol Biol Cell 2009 1.01
61 An aspirin-triggered lipoxin A4 stable analog displays a unique topical anti-inflammatory profile. J Immunol 2002 1.01
62 Antimicrobial aspects of inflammatory resolution in the mucosa: a role for proresolving mediators. J Immunol 2011 1.01
63 Central role for endothelial human deneddylase-1/SENP8 in fine-tuning the vascular inflammatory response. J Immunol 2012 0.98
64 Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 inhibit human neutrophil migration: comparisons between synthetic 15 epimers in chemotaxis and transmigration with microvessel endothelial cells and epithelial cells. J Immunol 2003 0.96
65 Inflammation-associated repression of vasodilator-stimulated phosphoprotein (VASP) reduces alveolar-capillary barrier function during acute lung injury. FASEB J 2009 0.96
66 Anti-inflammatory actions of adrenomedullin through fine tuning of HIF stabilization. FASEB J 2011 0.96
67 Expression and function of bactericidal/permeability-increasing protein in human genital tract epithelial cells. J Infect Dis 2006 0.95
68 Role of complement component C5 in cerebral ischemia/reperfusion injury. Brain Res 2006 0.94
69 An endogenously anti-inflammatory role for methylation in mucosal inflammation identified through metabolite profiling. J Immunol 2011 0.92
70 Hypoxia inducible factor-1 (HIF-1)-mediated repression of cystic fibrosis transmembrane conductance regulator (CFTR) in the intestinal epithelium. FASEB J 2008 0.92
71 Adenosine signaling mediates SUMO-1 modification of IkappaBalpha during hypoxia and reoxygenation. J Biol Chem 2009 0.91
72 Activated fluid transport regulates bacterial-epithelial interactions and significantly shifts the murine colonic microbiome. Gut Microbes 2012 0.90
73 Functional and biochemical characterization of epithelial bactericidal/permeability-increasing protein. Am J Physiol Gastrointest Liver Physiol 2005 0.89
74 Dynamic purine signaling and metabolism during neutrophil-endothelial interactions. Purinergic Signal 2005 0.88
75 Identification of hypoxia-inducible factor HIF-1A as transcriptional regulator of the A2B adenosine receptor during acute lung injury. J Immunol 2014 0.86
76 Induction of the von Hippel-Lindau tumor suppressor gene by late hypoxia limits HIF-1 expression. J Cell Biochem 2005 0.86
77 Implications of protein post-translational modifications in IBD. Inflamm Bowel Dis 2012 0.86
78 IFN-γ attenuates hypoxia-inducible factor (HIF) activity in intestinal epithelial cells through transcriptional repression of HIF-1β. J Immunol 2011 0.86
79 Transcriptional repression of Na-K-2Cl cotransporter NKCC1 by hypoxia-inducible factor-1. Am J Physiol Cell Physiol 2006 0.86
80 Identification of Pur alpha as a new hypoxia response factor responsible for coordinated induction of the beta 2 integrin family. J Immunol 2007 0.85
81 Decreased neprilysin and pulmonary vascular remodeling in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2010 0.85
82 Dexamethasone-pDMAEMA polymeric conjugates reduce inflammatory biomarkers in human intestinal epithelial monolayers. J Control Release 2008 0.84
83 Epithelial function in eosinophilic gastrointestinal diseases. Immunol Allergy Clin North Am 2009 0.84
84 IFN-γ-mediated induction of an apical IL-10 receptor on polarized intestinal epithelia. J Immunol 2013 0.82
85 Model systems to investigate neutrophil adhesion and chemotaxis. Methods Mol Biol 2007 0.82
86 Lipid mediator networks and leukocyte transmigration. Prostaglandins Leukot Essent Fatty Acids 2005 0.82
87 Oxygen metabolism and barrier regulation in the intestinal mucosa. J Clin Invest 2016 0.81
88 Cholera toxin potentiates influences of IFN-gamma through activation of NF-kappaB and release of tumor necrosis factor-alpha. J Interferon Cytokine Res 2005 0.80
89 Assessing oxygen sensitivity of the multidrug resistance (MDR) gene. Methods Enzymol 2004 0.79
90 HIF-dependent regulation of AKAP12 (gravin) in the control of human vascular endothelial function. FASEB J 2013 0.78
91 Mammalian Ste20-like kinase 4 promotes pituitary cell proliferation and survival under hypoxia. Mol Endocrinol 2015 0.78
92 Lactase gene transcription is activated in response to hypoxia in intestinal epithelial cells. Mol Genet Metab 2002 0.76
93 Events at the host-microbial interface of the gastrointestinal tract. I. Adaptation to a microbial world: role of epithelial bactericidal/permeability-increasing protein. Am J Physiol Gastrointest Liver Physiol 2005 0.76
94 Swimming through the gut: implications of fluid transport on the microbiome. Dig Dis Sci 2013 0.75
95 Cell-cell interactions on solid matrices. Methods Mol Biol 2006 0.75