Gallium-labelled peptides for imaging of inflammation.

Absorption, distribution and excretion of intravenously injected (68)Ge/ (68)Ga generator eluate in healthy rats, and estimation of human radiation dosimetry. EJNMMI Res (2015) 1.38

Targeting post-infarct inflammation by PET imaging: comparison of (68)Ga-citrate and (68)Ga-DOTATATE with (18)F-FDG in a mouse model. Eur J Nucl Med Mol Imaging (2014) 0.84

68Ga-DOTA-Siglec-9--a new imaging tool to detect synovitis. Arthritis Res Ther (2015) 0.79

Using 5-deoxy-5-[18F]fluororibose to glycosylate peptides for positron emission tomography. Nat Protoc (2013) 0.79

Design and applications of bispecific heterodimers: molecular imaging and beyond. Mol Pharm (2014) 0.78

Feasibility of (68)Ga-labeled Siglec-9 peptide for the imaging of acute lung inflammation: a pilot study in a porcine model of acute respiratory distress syndrome. Am J Nucl Med Mol Imaging (2016) 0.77

Imaging Pulmonary Inflammation. J Nucl Med (2016) 0.76

(18)F-Labeling of Mannan for Inflammation Research with Positron Emission Tomography. ACS Med Chem Lett (2016) 0.75

A simple method for in vivo labelling of infiltrating leukocytes in the mouse retina using indocyanine green dye. Dis Model Mech (2015) 0.75

Vascular adhesion protein 1 in the eye. J Ophthalmol (2013) 0.75

Completing the Pain Circuit: Recent Advances in Imaging Pain and Inflammation beyond the Central Nervous System. Rambam Maimonides Med J (2013) 0.75

Angiogenesis as a novel component of inflammatory bowel disease pathogenesis. Gastroenterology (2006) 2.35

Radiolabeled multimeric cyclic RGD peptides as integrin alphavbeta3 targeted radiotracers for tumor imaging. Mol Pharm (2006) 2.16

A 90-kilodalton endothelial cell molecule mediating lymphocyte binding in humans. Science (1992) 2.06

Cell-surface enzymes in control of leukocyte trafficking. Nat Rev Immunol (2005) 1.76

Are radiogallium-labelled DOTA-conjugated somatostatin analogues superior to those labelled with other radiometals? Eur J Nucl Med Mol Imaging (2007) 1.72

Absence of the endothelial oxidase AOC3 leads to abnormal leukocyte traffic in vivo. Immunity (2005) 1.69

Induction and function of vascular adhesion protein-1 at sites of inflammation. J Exp Med (1993) 1.58

Vascular amine oxidases are needed for leukocyte extravasation into inflamed joints in vivo. Arthritis Rheum (2006) 1.52

68Ga- and 111In-labelled DOTA-RGD peptides for imaging of alphavbeta3 integrin expression. Eur J Nucl Med Mol Imaging (2008) 1.43

VAP-1: an adhesin and an enzyme. Trends Immunol (2001) 1.41

Integrin alpha V beta 3 as a target for treatment of rheumatoid arthritis and related rheumatic diseases. Ann Rheum Dis (2002) 1.34

Imaging infection/inflammation in the new millennium. Eur J Nucl Med (2001) 1.34

Vascular adhesion protein-1 and ICAM-1 support the adhesion of tumor-infiltrating lymphocytes to tumor endothelium in human hepatocellular carcinoma. J Immunol (1998) 1.33

A cell surface amine oxidase directly controls lymphocyte migration. Immunity (2001) 1.24

68Ga-DOTANOC PET/CT clinical impact in patients with neuroendocrine tumors. J Nucl Med (2010) 1.19

Vascular adhesion protein 1 (VAP-1) mediates lymphocyte subtype-specific, selectin-independent recognition of vascular endothelium in human lymph nodes. J Exp Med (1997) 1.18

68Ga-DOTANOC: biodistribution and dosimetry in patients affected by neuroendocrine tumors. Eur J Nucl Med Mol Imaging (2007) 1.15

68Ga-siderophores for PET imaging of invasive pulmonary aspergillosis: proof of principle. J Nucl Med (2010) 1.14

[68Ga]NODAGA-RGD for imaging αvβ3 integrin expression. Eur J Nucl Med Mol Imaging (2011) 1.09

The oxidase activity of vascular adhesion protein-1 (VAP-1) induces endothelial E- and P-selectins and leukocyte binding. Blood (2007) 1.05

In vivo detection of vascular adhesion protein-1 in experimental inflammation. Am J Pathol (2000) 1.03

Activation of vascular adhesion protein-1 on liver endothelium results in an NF-kappaB-dependent increase in lymphocyte adhesion. Hepatology (2007) 1.01

Comparison of 18F-FDG and 68Ga PET imaging in the assessment of experimental osteomyelitis due to Staphylococcus aureus. Eur J Nucl Med Mol Imaging (2005) 1.00

Siglec-9 is a novel leukocyte ligand for vascular adhesion protein-1 and can be used in PET imaging of inflammation and cancer. Blood (2011) 0.97

68Ga-DOTA-RGD peptide: biodistribution and binding into atherosclerotic plaques in mice. Eur J Nucl Med Mol Imaging (2009) 0.96

68Ga-citrate PET/CT for evaluating patients with infections of the bone: preliminary results. J Nucl Med (2010) 0.96

Nuclear medicine methods for evaluation of skeletal infection among other diagnostic modalities. Q J Nucl Med Mol Imaging (2006) 0.94

Uptake of 68gallium in atherosclerotic plaques in LDLR-/-ApoB100/100 mice. EJNMMI Res (2011) 0.94

Non-specific binding of [18F]FDG to calcifications in atherosclerotic plaques: experimental study of mouse and human arteries. Eur J Nucl Med Mol Imaging (2006) 0.93

Clinically proven radiopharmaceuticals for infection imaging: mechanisms and applications. Semin Nucl Med (2009) 0.93

Synthesis, 68Ga labeling and preliminary evaluation of DOTA peptide binding vascular adhesion protein-1: a potential PET imaging agent for diagnosing osteomyelitis. Nucl Med Biol (2009) 0.93

Vascular adhesion protein-1 enhances tumor growth by supporting recruitment of Gr-1+CD11b+ myeloid cells into tumors. Cancer Res (2009) 0.93

PET imaging of inflammation and adenocarcinoma xenografts using vascular adhesion protein 1 targeting peptide 68Ga-DOTAVAP-P1: comparison with 18F-FDG. Eur J Nucl Med Mol Imaging (2010) 0.92

A peptide inhibitor of vascular adhesion protein-1 (VAP-1) blocks leukocyte-endothelium interactions under shear stress. Eur J Immunol (2004) 0.92

(68)Ga-DOTA-NOC PET/CT in comparison with CT for the detection of bone metastasis in patients with neuroendocrine tumours. Eur J Nucl Med Mol Imaging (2010) 0.91

68Ga-DOTANOC PET/CT allows somatostatin receptor imaging in idiopathic pulmonary fibrosis: preliminary results. J Nucl Med (2010) 0.90

PET imaging of acute and chronic inflammation in living mice. Eur J Nucl Med Mol Imaging (2007) 0.90

(68)Ga-DOTAVAP-P1 PET imaging capable of demonstrating the phase of inflammation in healing bones and the progress of infection in osteomyelitic bones. Eur J Nucl Med Mol Imaging (2007) 0.89

Emerging role of FDG-PET/CT in assessing atherosclerosis in large arteries. Eur J Nucl Med Mol Imaging (2008) 0.89

Radiopharmaceuticals for scintigraphic imaging of infection and inflammation. Inflamm Res (2001) 0.88

Mini-PEG spacering of VAP-1-targeting 68Ga-DOTAVAP-P1 peptide improves PET imaging of inflammation. EJNMMI Res (2011) 0.87

Vascular adhesion protein 1 mediates binding of immunotherapeutic effector cells to tumor endothelium. J Immunol (2001) 0.84

A new germanium-63/gallium-68 generator. J Nucl Med (1978) 0.83

Preliminary evaluation of novel 68Ga-DOTAVAP-PEG-P2 peptide targeting vascular adhesion protein-1. Clin Physiol Funct Imaging (2009) 0.82

Vascular adhesion protein-1 (VAP-1) is overexpressed in psoriatic patients. J Eur Acad Dermatol Venereol (2007) 0.81

Vimentin function in lymphocyte adhesion and transcellular migration. Nat Cell Biol (2006) 2.87

Prognostic relevance of 18-F FDG PET/CT in newly diagnosed multiple myeloma patients treated with up-front autologous transplantation. Blood (2011) 2.74

Early prediction of persistent organ failure by soluble CD73 in patients with acute pancreatitis*. Crit Care Med (2014) 2.68

Intratumoral lymphatics are essential for the metastatic spread and prognosis in squamous cell carcinomas of the head and neck region. Cancer Res (2003) 2.39

Influence of trigger PSA and PSA kinetics on 11C-Choline PET/CT detection rate in patients with biochemical relapse after radical prostatectomy. J Nucl Med (2009) 1.87

Is there a role for ¹¹C-choline PET/CT in the early detection of metastatic disease in surgically treated prostate cancer patients with a mild PSA increase <1.5 ng/ml? Eur J Nucl Med Mol Imaging (2010) 1.85

The same endothelial receptor controls lymphocyte traffic both in vascular and lymphatic vessels. Eur J Immunol (2003) 1.77

Cell-surface enzymes in control of leukocyte trafficking. Nat Rev Immunol (2005) 1.76

CD73 is required for efficient entry of lymphocytes into the central nervous system during experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A (2008) 1.75

Diagnostic accuracy of 18F-FDG PET/CT in characterizing ovarian lesions and staging ovarian cancer: correlation with transvaginal ultrasonography, computed tomography, and histology. Nucl Med Commun (2007) 1.72

Absence of the endothelial oxidase AOC3 leads to abnormal leukocyte traffic in vivo. Immunity (2005) 1.69

A prospective comparison of 18F-fluorodeoxyglucose positron emission tomography-computed tomography, magnetic resonance imaging and whole-body planar radiographs in the assessment of bone disease in newly diagnosed multiple myeloma. Haematologica (2007) 1.59

Vascular adhesion protein-1 mediates adhesion and transmigration of lymphocytes on human hepatic endothelial cells. J Immunol (2002) 1.55

Vascular amine oxidases are needed for leukocyte extravasation into inflamed joints in vivo. Arthritis Rheum (2006) 1.52

Altered purinergic signaling in CD73-deficient mice inhibits tumor progression. Eur J Immunol (2011) 1.51

18F-FDG PET/CT impact on testicular tumours clinical management. Eur J Nucl Med Mol Imaging (2013) 1.49

18F-FDG PET in mucosa-associated lymphoid tissue (MALT) lymphoma. Leuk Lymphoma (2006) 1.48

Anti endothelial cell autoantibodies selectively activate SAPK/JNK signalling in Wegener's granulomatosis. J Am Soc Nephrol (2007) 1.47

Comparison of 18F-dopa PET/CT and 123I-MIBG scintigraphy in stage 3 and 4 neuroblastoma: a pilot study. Eur J Nucl Med Mol Imaging (2011) 1.46

Detection and localization of prostate cancer: correlation of (11)C-choline PET/CT with histopathologic step-section analysis. J Nucl Med (2005) 1.46

Ecto-5'-nucleotidase/CD73 enhances endothelial barrier function and sprouting in blood but not lymphatic vasculature. Eur J Immunol (2014) 1.43

The clinical use of PET with (11)C-acetate. Am J Nucl Med Mol Imaging (2011) 1.43

CLEVER-1 mediates lymphocyte transmigration through vascular and lymphatic endothelium. Blood (2004) 1.35

CB(1) signaling in forebrain and sympathetic neurons is a key determinant of endocannabinoid actions on energy balance. Cell Metab (2010) 1.33

Granulocyte transmigration through the endothelium is regulated by the oxidase activity of vascular adhesion protein-1 (VAP-1). Blood (2004) 1.31

Tumor infiltrating immune cells and outcome of Merkel cell carcinoma: a population-based study. Clin Cancer Res (2012) 1.29

Preclinical in vivo study of new insulin-like growth factor-I receptor--specific inhibitor in Ewing's sarcoma. Clin Cancer Res (2007) 1.25

Rules of recruitment for Th1 and Th2 lymphocytes in inflamed liver: a role for alpha-4 integrin and vascular adhesion protein-1. Immunity (2005) 1.23

Lymphocyte homing to the gut: attraction, adhesion, and commitment. Immunol Rev (2005) 1.19

68Ga-DOTANOC PET/CT clinical impact in patients with neuroendocrine tumors. J Nucl Med (2010) 1.19

Type and location of tumor-infiltrating macrophages and lymphatic vessels predict survival of colorectal cancer patients. Int J Cancer (2011) 1.18

Crystal structure of the human vascular adhesion protein-1: unique structural features with functional implications. Protein Sci (2005) 1.18

Liver steatosis coexists with myocardial insulin resistance and coronary dysfunction in patients with type 2 diabetes. Am J Physiol Endocrinol Metab (2006) 1.15

Homing of mucosal lymphocytes to the liver in the pathogenesis of hepatic complications of inflammatory bowel disease. Lancet (2002) 1.13

Common lymphatic endothelial and vascular endothelial receptor-1 mediates the transmigration of regulatory T cells across human hepatic sinusoidal endothelium. J Immunol (2011) 1.13

Vascular adhesion protein-1 is involved in both acute and chronic inflammation in the mouse. Am J Pathol (2005) 1.13

Epithelial and mesenchymal tumor compartments exhibit in vivo complementary patterns of vascular perfusion and glucose metabolism. Neoplasia (2007) 1.12

Human Siglec-10 can bind to vascular adhesion protein-1 and serves as its substrate. Blood (2009) 1.10

A novel model of CCl4-induced cirrhosis with ascites in the mouse. J Hepatol (2009) 1.10

Pim-1 kinase expression predicts radiation response in squamocellular carcinoma of head and neck and is under the control of epidermal growth factor receptor. Neoplasia (2009) 1.09

68Ga-DOTA-NOC: a new PET tracer for evaluating patients with bronchial carcinoid. Nucl Med Commun (2009) 1.09

The detection of micromolar pericellular ATP pool on lymphocyte surface by using lymphoid ecto-adenylate kinase as intrinsic ATP sensor. Mol Biol Cell (2006) 1.08

The prototype endothelial marker PAL-E is a leukocyte trafficking molecule. Blood (2009) 1.08

Islet beta-cell-specific T cells can use different homing mechanisms to infiltrate and destroy pancreatic islets. Am J Pathol (2007) 1.07

Soluble purine-converting enzymes circulate in human blood and regulate extracellular ATP level via counteracting pyrophosphatase and phosphotransfer reactions. FASEB J (2003) 1.06

Different role of CD73 in leukocyte trafficking via blood and lymph vessels. Blood (2011) 1.06

Potential pitfalls of 18F-FDG PET in a large series of patients treated for malignant lymphoma: prevalence and scan interpretation. Nucl Med Commun (2005) 1.06

Intravascular ADP and soluble nucleotidases contribute to acute prothrombotic state during vigorous exercise in humans. J Physiol (2007) 1.06

Origins of serum semicarbazide-sensitive amine oxidase. Circ Res (2004) 1.05

Antitumor activity of sustained N-myc reduction in rhabdomyosarcomas and transcriptional block by antigene therapy. Clin Cancer Res (2011) 1.05

PET/CT imaging in different types of lung cancer: an overview. Eur J Radiol (2011) 1.04

Nuclear imaging of inflammation: homing-associated molecules as targets. EJNMMI Res (2013) 1.04

Molecular identification of PAL-E, a widely used endothelial-cell marker. Blood (2005) 1.03

Regulation of mucosal addressin cell adhesion molecule 1 expression in human and mice by vascular adhesion protein 1 amine oxidase activity. Hepatology (2011) 1.02

The evidence for two opposite, ATP-generating and ATP-consuming, extracellular pathways on endothelial and lymphoid cells. Biochem J (2002) 1.02

IFN-beta regulates CD73 and adenosine expression at the blood-brain barrier. Eur J Immunol (2008) 1.01

Enzyme-coupled assays for simultaneous detection of nanomolar ATP, ADP, AMP, adenosine, inosine and pyrophosphate concentrations in extracellular fluids. Biochim Biophys Acta (2012) 1.00

CD73 participates in cellular multiresistance program and protects against TRAIL-induced apoptosis. J Immunol (2008) 0.99

IFN-alpha induced adenosine production on the endothelium: a mechanism mediated by CD73 (ecto-5'-nucleotidase) up-regulation. J Immunol (2004) 0.99

Comparison between 68Ga-DOTA-NOC and 18F-DOPA PET for the detection of gastro-entero-pancreatic and lung neuro-endocrine tumours. Eur J Nucl Med Mol Imaging (2008) 0.99

18F-FDG PET in malignant lymphoma: significance of positive findings. Eur J Nucl Med Mol Imaging (2005) 0.98

Role of ¹⁸F-choline PET/CT in suspicion of relapse following definitive radiotherapy for prostate cancer. Eur J Nucl Med Mol Imaging (2013) 0.98

Macrophage mannose receptor on lymphatics controls cell trafficking. Blood (2008) 0.98

ATP-consuming and ATP-generating enzymes secreted by pancreas. J Biol Chem (2006) 0.97

Diabetogenic T cells are primed both in pancreatic and gut-associated lymph nodes in NOD mice. Eur J Immunol (2003) 0.97

Mannose receptor (MR) and common lymphatic endothelial and vascular endothelial receptor (CLEVER)-1 direct the binding of cancer cells to the lymph vessel endothelium. Cancer Res (2003) 0.97

Adherent leukocytes prevent adenosine formation and impair endothelial barrier function by Ecto-5'-nucleotidase/CD73-dependent mechanism. J Biol Chem (2003) 0.97

Circulating inflammatory endothelial cells contribute to endothelial progenitor cell dysfunction in patients with vasculitis and kidney involvement. J Am Soc Nephrol (2005) 0.96

Insulin-regulated increase of soluble vascular adhesion protein-1 in diabetes. Am J Pathol (2002) 0.96

Evaluation of unusual neuroendocrine tumours by means of 68Ga-DOTA-NOC PET. Biomed Pharmacother (2008) 0.95

Ly6C induces clustering of LFA-1 (CD11a/CD18) and is involved in subtype-specific adhesion of CD8 T cells. J Immunol (2003) 0.95

Reactive oxygen species deficiency induces autoimmunity with type 1 interferon signature. Antioxid Redox Signal (2014) 0.94

Assessment of a chemically induced model of lung squamous cell carcinoma in mice by 18F-FDG small-animal PET. Nucl Med Commun (2007) 0.94

Semicarbazide sensitive amine oxidase overexpression has dual consequences: insulin mimicry and diabetes-like complications. FASEB J (2004) 0.94

Stromal cell-derived factor 1 (CXCL12) induces human cell migration into human lymph nodes transplanted into SCID mice. J Immunol (2002) 0.94

Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis. J Clin Invest (2014) 0.93

Synthesis, 68Ga labeling and preliminary evaluation of DOTA peptide binding vascular adhesion protein-1: a potential PET imaging agent for diagnosing osteomyelitis. Nucl Med Biol (2009) 0.93

A novel GGA-binding site is required for intracellular sorting mediated by stabilin-1. Mol Cell Biol (2009) 0.93

Vascular adhesion protein-1 enhances tumor growth by supporting recruitment of Gr-1+CD11b+ myeloid cells into tumors. Cancer Res (2009) 0.93

PET imaging of inflammation and adenocarcinoma xenografts using vascular adhesion protein 1 targeting peptide 68Ga-DOTAVAP-P1: comparison with 18F-FDG. Eur J Nucl Med Mol Imaging (2010) 0.92

A peptide inhibitor of vascular adhesion protein-1 (VAP-1) blocks leukocyte-endothelium interactions under shear stress. Eur J Immunol (2004) 0.92

IFN-beta protects from vascular leakage via up-regulation of CD73. Eur J Immunol (2007) 0.92

Efficacy of PHA-848125, a cyclin-dependent kinase inhibitor, on the K-Ras(G12D)LA2 lung adenocarcinoma transgenic mouse model: evaluation by multimodality imaging. Mol Cancer Ther (2010) 0.92

(68)Ga-DOTA-NOC PET/CT in comparison with CT for the detection of bone metastasis in patients with neuroendocrine tumours. Eur J Nucl Med Mol Imaging (2010) 0.91

Ly6C supports preferential homing of central memory CD8+ T cells into lymph nodes. Eur J Immunol (2011) 0.91

The role of 11C-choline PET imaging in the early detection of recurrence in surgically treated prostate cancer patients with very low PSA level <0.5 ng/mL. Clin Nucl Med (2013) 0.90

Clever-1/Stabilin-1 regulates lymphocyte migration within lymphatics and leukocyte entrance to sites of inflammation. Eur J Immunol (2009) 0.90

Ectoenzymes in leukocyte migration and their therapeutic potential. Semin Immunopathol (2014) 0.90

68Ga-DOTANOC PET/CT allows somatostatin receptor imaging in idiopathic pulmonary fibrosis: preliminary results. J Nucl Med (2010) 0.90

18F-DOPA PET/CT and neuroendocrine tumours. Eur J Nucl Med Mol Imaging (2006) 0.90

(68)Ga-DOTAVAP-P1 PET imaging capable of demonstrating the phase of inflammation in healing bones and the progress of infection in osteomyelitic bones. Eur J Nucl Med Mol Imaging (2007) 0.89

Increased intravitreal adenosine 5'-triphosphate, adenosine 5'-diphosphate and adenosine 5'-monophosphate levels in patients with proliferative diabetic retinopathy. Acta Ophthalmol (2014) 0.89

18F-DOPA PET/CT in neuroblastoma: comparison of conventional imaging with CT/MR. Clin Nucl Med (2012) 0.89

11C-acetate PET for early prediction of sunitinib response in metastatic renal cell carcinoma. Tumori (2009) 0.89

Value of FDG PET/CT in patients with treated ovarian cancer and raised CA125 serum levels. Mol Imaging Biol (2012) 0.89

(18)F-FDG PET/CT for the assessment of disease extension and activity in patients with sarcoidosis: results of a preliminary prospective study. Clin Nucl Med (2013) 0.88

Homing-associated molecules CD73 and VAP-1 as targets to prevent harmful inflammations and cancer spread. FEBS Lett (2011) 0.88

Present and future of PET and PET/CT in gynaecologic malignancies. Eur J Radiol (2010) 0.88

Role of 11C-choline PET/CT in the re-staging of prostate cancer patients with biochemical relapse and negative results at bone scintigraphy. Eur J Radiol (2012) 0.87

Metabolism of circulating ADP in the bloodstream is mediated via integrated actions of soluble adenylate kinase-1 and NTPDase1/CD39 activities. FASEB J (2012) 0.87