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1
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Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism.
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Proc Natl Acad Sci U S A
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2007
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2.10
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2
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A finite element model of the human knee joint for the study of tibio-femoral contact.
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J Biomech Eng
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2002
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1.98
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3
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Buffered platelet-rich plasma enhances mesenchymal stem cell proliferation and chondrogenic differentiation.
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Tissue Eng Part C Methods
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2009
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1.79
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4
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Osteocytes as mechanosensors in the inhibition of bone resorption due to mechanical loading.
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2007
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1.79
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5
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Mechanically induced osteogenic differentiation--the role of RhoA, ROCKII and cytoskeletal dynamics.
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J Cell Sci
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2009
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1.66
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6
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Oscillatory fluid flow affects human marrow stromal cell proliferation and differentiation.
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J Orthop Res
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2004
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1.62
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7
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The role of mechanical signals in regulating chondrogenesis and osteogenesis of mesenchymal stem cells.
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Birth Defects Res C Embryo Today
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2010
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1.34
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8
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Fluid flow induced PGE2 release by bone cells is reduced by glycocalyx degradation whereas calcium signals are not.
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Biorheology
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2003
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1.33
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9
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Substance P signaling contributes to the vascular and nociceptive abnormalities observed in a tibial fracture rat model of complex regional pain syndrome type I.
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Pain
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2004
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1.29
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10
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Non-canonical Wnt signaling and N-cadherin related beta-catenin signaling play a role in mechanically induced osteogenic cell fate.
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PLoS One
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2009
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1.26
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11
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Effects of short-term recovery periods on fluid-induced signaling in osteoblastic cells.
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J Biomech
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2005
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1.26
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12
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How the stiffness of meniscal attachments and meniscal material properties affect tibio-femoral contact pressure computed using a validated finite element model of the human knee joint.
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J Biomech
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2003
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1.24
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13
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Capsaicin-sensitive sensory neurons contribute to the maintenance of trabecular bone integrity.
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J Bone Miner Res
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2004
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1.22
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14
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Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells.
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FASEB J
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2010
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1.20
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15
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The role of actin cytoskeleton in oscillatory fluid flow-induced signaling in MC3T3-E1 osteoblasts.
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Am J Physiol Cell Physiol
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2007
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1.13
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16
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Primary cilia-mediated mechanotransduction in human mesenchymal stem cells.
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2012
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1.11
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17
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The Role of Primary Cilia in Mesenchymal Stem Cell Differentiation: A Pivotal Switch in Guiding Lineage Commitment.
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Cell Mol Bioeng
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2010
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1.10
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18
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The sensitivity of tibiofemoral contact pressure to the size and shape of the lateral and medial menisci.
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J Orthop Res
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2004
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1.09
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19
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Osteoblastic cells have refractory periods for fluid-flow-induced intracellular calcium oscillations for short bouts of flow and display multiple low-magnitude oscillations during long-term flow.
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J Biomech
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2003
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1.09
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20
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Beta1 integrins mediate mechanosensitive signaling pathways in osteocytes.
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Calcif Tissue Int
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2010
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1.09
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21
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The epigenetic mechanism of mechanically induced osteogenic differentiation.
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J Biomech
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2010
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1.07
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22
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P2Y purinoceptors are responsible for oscillatory fluid flow-induced intracellular calcium mobilization in osteoblastic cells.
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J Biol Chem
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2002
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1.05
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23
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Primary cilia: cellular sensors for the skeleton.
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Anat Rec (Hoboken)
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2008
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1.05
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24
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A role for the primary cilium in paracrine signaling between mechanically stimulated osteocytes and mesenchymal stem cells.
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Biochem Biophys Res Commun
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2011
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1.03
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25
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Mechanically induced osteogenic lineage commitment of stem cells.
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Stem Cell Res Ther
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2013
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1.00
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26
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The periosteum as a cellular source for functional tissue engineering.
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Tissue Eng Part A
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2009
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0.99
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27
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Mechanosensing by the primary cilium: deletion of Kif3A reduces bone formation due to loading.
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PLoS One
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2012
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0.99
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28
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The mechanics of the primary cilium: an intricate structure with complex function.
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J Biomech
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2011
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0.97
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29
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Mesenchymal stem cell mechanobiology.
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Curr Osteoporos Rep
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2010
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0.95
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30
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A substance P receptor (NK1) antagonist enhances the widespread osteoporotic effects of sciatic nerve section.
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Bone
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2003
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0.95
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31
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Substance P stimulates bone marrow stromal cell osteogenic activity, osteoclast differentiation, and resorption activity in vitro.
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Bone
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2009
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0.95
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32
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Osteocyte primary cilium and its role in bone mechanotransduction.
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Ann N Y Acad Sci
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2010
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0.95
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33
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Calcitonin-gene-related peptide stimulates stromal cell osteogenic differentiation and inhibits RANKL induced NF-kappaB activation, osteoclastogenesis and bone resorption.
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Bone
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2009
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0.94
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34
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Bone microstructure and its associated genetic variability in 12 inbred mouse strains: microCT study and in silico genome scan.
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Bone
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2007
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0.90
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35
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Mechanically induced intracellular calcium waves in osteoblasts demonstrate calcium fingerprints in bone cell mechanotransduction.
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Biomech Model Mechanobiol
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2006
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0.89
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36
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Time-dependent deformations in bone cells exposed to fluid flow in vitro: investigating the role of cellular deformation in fluid flow-induced signaling.
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J Biomech
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2007
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0.89
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37
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An experimental and computational analysis of primary cilia deflection under fluid flow.
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Comput Methods Biomech Biomed Engin
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2012
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0.88
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38
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Emerging role of primary cilia as mechanosensors in osteocytes.
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Bone
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2012
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0.86
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39
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Actin and ERK1/2-CEBPβ signaling mediates phagocytosis-induced innate immune response of osteoprogenitor cells.
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Biomaterials
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2011
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0.85
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40
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The primary cilium as a novel extracellular sensor in bone.
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Front Endocrinol (Lausanne)
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2012
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0.82
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41
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Focal adhesion kinase plays a role in osteoblast mechanotransduction in vitro but does not affect load-induced bone formation in vivo.
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PLoS One
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2012
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0.82
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42
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Oscillatory fluid flow influences primary cilia and microtubule mechanics.
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Cytoskeleton (Hoboken)
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2014
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43
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CXCR4 antagonism attenuates load-induced periosteal bone formation in mice.
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J Orthop Res
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2013
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0.79
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44
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Cycle number and waveform of fluid flow affect bovine articular chondrocytes.
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Biorheology
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2004
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45
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Novel early response genes in osteoblasts exposed to dynamic fluid flow.
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Philos Trans A Math Phys Eng Sci
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2010
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46
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Epigenetic changes during mechanically induced osteogenic lineage commitment.
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J Biomech Eng
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2015
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0.76
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47
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Effects of high frequency loading on RANKL and OPG mRNA expression in ST-2 murine stromal cells.
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BMC Musculoskelet Disord
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2009
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0.76
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Adenylyl cyclase 6 mediates loading-induced bone adaptation in vivo.
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FASEB J
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2013
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49
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Cellular and Molecular Bioengineering: A Tipping Point.
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Cell Mol Bioeng
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2012
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0.75
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50
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Finite element analysis as a tool for parametric prosthetic foot design and evaluation. Technique development in the solid ankle cushioned heel (SACH) foot.
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Comput Methods Biomech Biomed Engin
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2003
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0.75
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