PubRank

Christopher R Jacobs

Author PubWeight™ 54.36‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism. Proc Natl Acad Sci U S A 2007 2.10
2 A finite element model of the human knee joint for the study of tibio-femoral contact. J Biomech Eng 2002 1.98
3 Buffered platelet-rich plasma enhances mesenchymal stem cell proliferation and chondrogenic differentiation. Tissue Eng Part C Methods 2009 1.79
4 Osteocytes as mechanosensors in the inhibition of bone resorption due to mechanical loading. Bone 2007 1.79
5 Mechanically induced osteogenic differentiation--the role of RhoA, ROCKII and cytoskeletal dynamics. J Cell Sci 2009 1.66
6 Oscillatory fluid flow affects human marrow stromal cell proliferation and differentiation. J Orthop Res 2004 1.62
7 The role of mechanical signals in regulating chondrogenesis and osteogenesis of mesenchymal stem cells. Birth Defects Res C Embryo Today 2010 1.34
8 Fluid flow induced PGE2 release by bone cells is reduced by glycocalyx degradation whereas calcium signals are not. Biorheology 2003 1.33
9 Substance P signaling contributes to the vascular and nociceptive abnormalities observed in a tibial fracture rat model of complex regional pain syndrome type I. Pain 2004 1.29
10 Non-canonical Wnt signaling and N-cadherin related beta-catenin signaling play a role in mechanically induced osteogenic cell fate. PLoS One 2009 1.26
11 Effects of short-term recovery periods on fluid-induced signaling in osteoblastic cells. J Biomech 2005 1.26
12 How the stiffness of meniscal attachments and meniscal material properties affect tibio-femoral contact pressure computed using a validated finite element model of the human knee joint. J Biomech 2003 1.24
13 Capsaicin-sensitive sensory neurons contribute to the maintenance of trabecular bone integrity. J Bone Miner Res 2004 1.22
14 Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells. FASEB J 2010 1.20
15 The role of actin cytoskeleton in oscillatory fluid flow-induced signaling in MC3T3-E1 osteoblasts. Am J Physiol Cell Physiol 2007 1.13
16 Primary cilia-mediated mechanotransduction in human mesenchymal stem cells. Stem Cells 2012 1.11
17 The Role of Primary Cilia in Mesenchymal Stem Cell Differentiation: A Pivotal Switch in Guiding Lineage Commitment. Cell Mol Bioeng 2010 1.10
18 The sensitivity of tibiofemoral contact pressure to the size and shape of the lateral and medial menisci. J Orthop Res 2004 1.09
19 Osteoblastic cells have refractory periods for fluid-flow-induced intracellular calcium oscillations for short bouts of flow and display multiple low-magnitude oscillations during long-term flow. J Biomech 2003 1.09
20 Beta1 integrins mediate mechanosensitive signaling pathways in osteocytes. Calcif Tissue Int 2010 1.09
21 The epigenetic mechanism of mechanically induced osteogenic differentiation. J Biomech 2010 1.07
22 P2Y purinoceptors are responsible for oscillatory fluid flow-induced intracellular calcium mobilization in osteoblastic cells. J Biol Chem 2002 1.05
23 Primary cilia: cellular sensors for the skeleton. Anat Rec (Hoboken) 2008 1.05
24 A role for the primary cilium in paracrine signaling between mechanically stimulated osteocytes and mesenchymal stem cells. Biochem Biophys Res Commun 2011 1.03
25 Mechanically induced osteogenic lineage commitment of stem cells. Stem Cell Res Ther 2013 1.00
26 The periosteum as a cellular source for functional tissue engineering. Tissue Eng Part A 2009 0.99
27 Mechanosensing by the primary cilium: deletion of Kif3A reduces bone formation due to loading. PLoS One 2012 0.99
28 The mechanics of the primary cilium: an intricate structure with complex function. J Biomech 2011 0.97
29 Mesenchymal stem cell mechanobiology. Curr Osteoporos Rep 2010 0.95
30 A substance P receptor (NK1) antagonist enhances the widespread osteoporotic effects of sciatic nerve section. Bone 2003 0.95
31 Substance P stimulates bone marrow stromal cell osteogenic activity, osteoclast differentiation, and resorption activity in vitro. Bone 2009 0.95
32 Osteocyte primary cilium and its role in bone mechanotransduction. Ann N Y Acad Sci 2010 0.95
33 Calcitonin-gene-related peptide stimulates stromal cell osteogenic differentiation and inhibits RANKL induced NF-kappaB activation, osteoclastogenesis and bone resorption. Bone 2009 0.94
34 Bone microstructure and its associated genetic variability in 12 inbred mouse strains: microCT study and in silico genome scan. Bone 2007 0.90
35 Mechanically induced intracellular calcium waves in osteoblasts demonstrate calcium fingerprints in bone cell mechanotransduction. Biomech Model Mechanobiol 2006 0.89
36 Time-dependent deformations in bone cells exposed to fluid flow in vitro: investigating the role of cellular deformation in fluid flow-induced signaling. J Biomech 2007 0.89
37 An experimental and computational analysis of primary cilia deflection under fluid flow. Comput Methods Biomech Biomed Engin 2012 0.88
38 Emerging role of primary cilia as mechanosensors in osteocytes. Bone 2012 0.86
39 Actin and ERK1/2-CEBPβ signaling mediates phagocytosis-induced innate immune response of osteoprogenitor cells. Biomaterials 2011 0.85
40 The primary cilium as a novel extracellular sensor in bone. Front Endocrinol (Lausanne) 2012 0.82
41 Focal adhesion kinase plays a role in osteoblast mechanotransduction in vitro but does not affect load-induced bone formation in vivo. PLoS One 2012 0.82
42 Oscillatory fluid flow influences primary cilia and microtubule mechanics. Cytoskeleton (Hoboken) 2014 0.81
43 CXCR4 antagonism attenuates load-induced periosteal bone formation in mice. J Orthop Res 2013 0.79
44 Cycle number and waveform of fluid flow affect bovine articular chondrocytes. Biorheology 2004 0.78
45 Novel early response genes in osteoblasts exposed to dynamic fluid flow. Philos Trans A Math Phys Eng Sci 2010 0.78
46 Epigenetic changes during mechanically induced osteogenic lineage commitment. J Biomech Eng 2015 0.76
47 Effects of high frequency loading on RANKL and OPG mRNA expression in ST-2 murine stromal cells. BMC Musculoskelet Disord 2009 0.76
48 Adenylyl cyclase 6 mediates loading-induced bone adaptation in vivo. FASEB J 2013 0.76
49 Cellular and Molecular Bioengineering: A Tipping Point. Cell Mol Bioeng 2012 0.75
50 Finite element analysis as a tool for parametric prosthetic foot design and evaluation. Technique development in the solid ankle cushioned heel (SACH) foot. Comput Methods Biomech Biomed Engin 2003 0.75