Sean P Palecek

Author PubWeight™ 80.68‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Functional cardiomyocytes derived from human induced pluripotent stem cells. Circ Res 2009 7.09
2 Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling. Proc Natl Acad Sci U S A 2012 4.85
3 Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions. Nat Protoc 2012 3.22
4 Extracellular matrix promotes highly efficient cardiac differentiation of human pluripotent stem cells: the matrix sandwich method. Circ Res 2012 2.91
5 Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells. Nat Biotechnol 2012 2.33
6 3-D microwell culture of human embryonic stem cells. Biomaterials 2006 1.77
7 Retinoic acid and bone morphogenetic protein signaling synergize to efficiently direct epithelial differentiation of human embryonic stem cells. Stem Cells 2007 1.71
8 Effects of substrate mechanics on contractility of cardiomyocytes generated from human pluripotent stem cells. Int J Cell Biol 2012 1.63
9 The microwell control of embryoid body size in order to regulate cardiac differentiation of human embryonic stem cells. Biomaterials 2009 1.46
10 EAP1, a Candida albicans gene involved in binding human epithelial cells. Eukaryot Cell 2003 1.40
11 A global assessment of stem cell engineering. Tissue Eng Part A 2014 1.38
12 Inhibition of human embryonic stem cell differentiation by mechanical strain. J Cell Physiol 2006 1.36
13 Eap1p, an adhesin that mediates Candida albicans biofilm formation in vitro and in vivo. Eukaryot Cell 2007 1.32
14 Engineering the stem cell microenvironment. Biotechnol Prog 2007 1.23
15 TGFbeta/Activin/Nodal pathway in inhibition of human embryonic stem cell differentiation by mechanical strain. Biophys J 2008 1.22
16 Scalable culture and cryopreservation of human embryonic stem cells on microcarriers. Biotechnol Prog 2009 1.21
17 Antifungal activity from 14-helical beta-peptides. J Am Chem Soc 2006 1.21
18 Innovation in the culture and derivation of pluripotent human stem cells. Curr Opin Biotechnol 2008 1.18
19 Modulation of Wnt/β-catenin signaling in human embryonic stem cells using a 3-D microwell array. Biomaterials 2011 1.16
20 Cryopreservation of adherent human embryonic stem cells. Biotechnol Bioeng 2004 1.13
21 Directed differentiation of human embryonic stem cells to epidermal progenitors. Methods Mol Biol 2010 1.12
22 Distinct domains of the Candida albicans adhesin Eap1p mediate cell-cell and cell-substrate interactions. Microbiology 2008 1.12
23 Short alkylated peptoid mimics of antimicrobial lipopeptides. Antimicrob Agents Chemother 2010 1.08
24 Identification of Candida albicans genes that induce Saccharomyces cerevisiae cell adhesion and morphogenesis. Biotechnol Prog 2005 1.08
25 Analyzing the dose-dependence of the Saccharomyces cerevisiae global transcriptional response to methyl methanesulfonate and ionizing radiation. BMC Genomics 2006 1.02
26 Effect of sequence and structural properties on 14-helical beta-peptide activity against Candida albicans planktonic cells and biofilms. ACS Chem Biol 2009 0.97
27 Insulin inhibits cardiac mesoderm, not mesendoderm, formation during cardiac differentiation of human pluripotent stem cells and modulation of canonical Wnt signaling can rescue this inhibition. Stem Cells 2013 0.97
28 Protein-acrylamide copolymer hydrogels for array-based detection of tyrosine kinase activity from cell lysates. Biomacromolecules 2005 0.96
29 The response of human embryonic stem cell-derived endothelial cells to shear stress. Biotechnol Bioeng 2008 0.95
30 Development of macroporous poly(ethylene glycol) hydrogel arrays within microfluidic channels. Biomacromolecules 2010 0.93
31 The utilization of a Saccharomyces cerevisiae HUG1P-GFP promoter-reporter construct for the selective detection of DNA damage. Mutat Res 2007 0.92
32 Development of Scalable Culture Systems for Human Embryonic Stem Cells. Biochem Eng J 2010 0.91
33 A small molecule inhibitor of SRC family kinases promotes simple epithelial differentiation of human pluripotent stem cells. PLoS One 2013 0.91
34 Human embryonic stem cell-derived keratinocytes exhibit an epidermal transcription program and undergo epithelial morphogenesis in engineered tissue constructs. Tissue Eng Part A 2010 0.91
35 Hydrogel-based protein array for quantifying epidermal growth factor receptor activity in cell lysates. Anal Biochem 2009 0.90
36 Use of protein-acrylamide copolymer hydrogels for measuring protein concentration and activity. Anal Biochem 2004 0.89
37 Structure-activity relationships among antifungal nylon-3 polymers: identification of materials active against drug-resistant strains of Candida albicans. J Am Chem Soc 2014 0.89
38 Polyelectrolyte multilayers fabricated from antifungal β-peptides: design of surfaces that exhibit antifungal activity against Candida albicans. Biomacromolecules 2010 0.88
39 Generation and differentiation of human embryonic stem cell-derived keratinocyte precursors. Tissue Eng 2006 0.88
40 Effect of pH, counter ion, and phosphate concentration on the glass transition temperature of freeze-dried sugar-phosphate mixtures. Pharm Res 2004 0.88
41 Phase behavior of freeze-dried phospholipid-cholesterol mixtures stabilized with trehalose. Biochim Biophys Acta 2005 0.87
42 Concise review: tissue-specific microvascular endothelial cells derived from human pluripotent stem cells. Stem Cells 2014 0.87
43 Engineering the human pluripotent stem cell microenvironment to direct cell fate. Biotechnol Adv 2013 0.87
44 Microwell regulation of pluripotent stem cell self-renewal and differentiation. Bionanoscience 2012 0.86
45 Efficient generation of functional epithelial and epidermal cells from human pluripotent stem cells under defined conditions. Tissue Eng Part C Methods 2013 0.86
46 Saccharomyces cerevisiae JEN1 promoter activity is inversely related to concentration of repressing sugar. Appl Environ Microbiol 2004 0.86
47 Photocleavable peptide hydrogel arrays for MALDI-TOF analysis of kinase activity. Analyst 2006 0.86
48 Modeling the blood-brain barrier using stem cell sources. Fluids Barriers CNS 2013 0.86
49 Electroporation of human embryonic stem cells: Small and macromolecule loading and DNA transfection. Biotechnol Prog 2006 0.85
50 Enzyme encapsulation in permeabilized Saccharomyces cerevisiae cells. Biotechnol Prog 2004 0.84
51 Fabrication and selective functionalization of amine-reactive polymer multilayers on topographically patterned microwell cell culture arrays. Biomacromolecules 2011 0.84
52 Quantifying the sensitivities of EGF receptor (EGFR) tyrosine kinase inhibitors in drug resistant non-small cell lung cancer (NSCLC) cells using hydrogel-based peptide array. Biosens Bioelectron 2010 0.84
53 Effects of 3D microwell culture on growth kinetics and metabolism of human embryonic stem cells. Biotechnol Appl Biochem 2012 0.83
54 Quantification of kinase activity in cell lysates via photopatterned macroporous poly(ethylene glycol) hydrogel arrays in microfluidic channels. Biomed Microdevices 2012 0.83
55 Hydrophobicity and helicity regulate the antifungal activity of 14-helical β-peptides. ACS Chem Biol 2014 0.82
56 Disruption of LRG1 inhibits mother-daughter separation in Saccharomyces cerevisiae. Yeast 2005 0.82
57 Influence of substrate composition on human embryonic stem cell differentiation and extracellular matrix production in embryoid bodies. Biotechnol Prog 2014 0.80
58 Matrix revolutions: a trinity of defined substrates for long-term expansion of human ESCs. Cell Stem Cell 2010 0.79
59 Effect of sugar-phosphate mixtures on the stability of DPPC membranes in dehydrated systems. Cryobiology 2004 0.78
60 Improving efficiency of human pluripotent stem cell differentiation platforms using an integrated experimental and computational approach. Biotechnol Bioeng 2013 0.78
61 Analysis of Cancer-Targeting Alkylphosphocholine Analogue Permeability Characteristics Using a Human Induced Pluripotent Stem Cell Blood-Brain Barrier Model. Mol Pharm 2016 0.78
62 Macroporous hydrogel micropillars for quantifying Met kinase activity in cancer cell lysates. Analyst 2012 0.77
63 Properties of resistant cells generated from lung cancer cell lines treated with EGFR inhibitors. BMC Cancer 2012 0.77
64 Activity assay of epidermal growth factor receptor tyrosine kinase inhibitors in triple-negative breast cancer cells using peptide-conjugated magnetic beads. Assay Drug Dev Technol 2012 0.75
65 Multiplexed tyrosine kinase activity detection in cancer cells using a hydrogel immobilized substrate. Anal Bioanal Chem 2013 0.75
66 Deletion of MAG1 and MRE11 enhances the sensitivity of the Saccharomyces cerevisiae HUG1P-GFP promoter-reporter construct to genotoxicity. Biosens Bioelectron 2008 0.75
67 Generation of Epithelial Cell Populations from Human Pluripotent Stem Cells Using a Small-Molecule Inhibitor of Src Family Kinases. Methods Mol Biol 2016 0.75
68 Incorporation of β-peptides enhances the antifungal activity and selectivity of the helical antimicrobial peptide aurein 1.2. ACS Chem Biol 2017 0.75
69 Platelet cryopreservation using a trehalose and phosphate formulation. Biotechnol Bioeng 2005 0.75
70 Editorial: stem cell engineering - discovery, diagnostics and therapies. Biotechnol J 2013 0.75