Aurora kinase-C-T191D is constitutively active mutant.

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Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells. EMBO J (2002) 4.54

Centrosome defects and genetic instability in malignant tumors. Cancer Res (1998) 3.32

Roles of Aurora kinases in mitosis and tumorigenesis. Mol Cancer Res (2007) 3.20

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Molecular mechanisms of kinetochore capture by spindle microtubules. Nature (2005) 2.90

Multinuclearity and increased ploidy caused by overexpression of the aurora- and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells. Cancer Res (1998) 2.63

Aurora-C kinase supports mitotic progression in the absence of Aurora-B. Cell Cycle (2009) 1.82

Centrosome hyperamplification in human cancer: chromosome instability induced by p53 mutation and/or Mdm2 overexpression. Oncogene (1999) 1.71

Homozygous mutation of AURKC yields large-headed polyploid spermatozoa and causes male infertility. Nat Genet (2007) 1.71

Mechanism of Aurora-B degradation and its dependency on intact KEN and A-boxes: identification of an aneuploidy-promoting property. Mol Cell Biol (2005) 1.67

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Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells. Cell Motil Cytoskeleton (2004) 1.59

Mitotic kinase expression and colorectal cancer progression. J Natl Cancer Inst (1999) 1.44

Dynamic localization and functional implications of Aurora-C kinase during male mouse meiosis. Dev Biol (2006) 1.43

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Direct association with inner centromere protein (INCENP) activates the novel chromosomal passenger protein, Aurora-C. J Biol Chem (2004) 1.23

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The absence of p53 aggravates polyploidy and centrosome number abnormality induced by Aurora-C overexpression. Cell Cycle (2005) 0.90

The protein kinase Aurora C phosphorylates TRF2. Cell Cycle (2007) 0.84

Nocturnal activation of aurora C in rat pineal gland: its role in the norepinephrine-induced phosphorylation of histone H3 and gene expression. Endocrinology (2008) 0.82

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Prevalence of active hepatitis c virus infection in district Mansehra Pakistan. Virol J (2010) 1.02

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Frequency distribution of HCV genotypes among chronic hepatitis C patients of Khyber Pakhtunkhwa. Virol J (2011) 0.92

Multiple interactions of complement Factor H with its ligands in solution: a progress report. Adv Exp Med Biol (2010) 0.89

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The effects of endosulfan on the testes of bluegill fish, Lepomis macrochirus: a histopathological study. Arch Environ Contam Toxicol (2006) 0.84

Prevalence of hepatitis B virus genotypes in HBsAg positive individuals of Afghanistan. Virol J (2011) 0.84

Response rates of standard interferon therapy in chronic HCV patients of Khyber Pakhtunkhwa (KPK). Virol J (2012) 0.82

Active hepatitis C infection and HCV genotypes prevalent among the IDUs of Khyber Pakhtunkhwa. Virol J (2011) 0.82

Prevalence of active HCV infection among the blood donors of Khyber Pakhtunkwa and FATA region of Pakistan and evaluation of the screening tests for anti-HCV. Virol J (2011) 0.78

PCR/RFLP-based analysis of genetically distinct Plasmodium vivax population of Pvmsp-3α and Pvmsp-3β genes in Pakistan. Malar J (2014) 0.77

Response to combination therapy of HCV 3a infected Pakistani patients and the role of NS5A protein. Virol J (2011) 0.77

Comparative biotransformation of radiolabeled [(14)C]omapatrilat and stable-labeled [(13)C(2)]omapatrilat after oral administration to rats, dogs, and humans. Drug Metab Dispos (2003) 0.77

Cis-regulatory elements affecting the Nanos gene promoter in the germline stem cells. J Biotechnol (2009) 0.77

Application of DNA comet assay for detection of radiation treatment of grams and pulses. J Food Sci Technol (2010) 0.75

Duplex PCR assay for the detection of avian adeno virus and chicken anemia virus prevalent in Pakistan. Virol J (2011) 0.75

The effects and underlying mechanism of interferon therapy on body weight and body composition. Pak J Pharm Sci (2013) 0.75

Virological Response to Conventional Interferon Therapy Combined with Ribavirin against Various HCV Genotypes in Khyber Pakhtunkhwa, Pakistan. Asian Pac J Cancer Prev (2016) 0.75

Novelity in GB virus C/hepatitis G virus and its controversy. J Ayub Med Coll Abbottabad (2002) 0.75

Metabolism of [14C]gemopatrilat after oral administration to rats, dogs, and humans. Drug Metab Dispos (2006) 0.75

Molecular detection of Toxoplasma gondii in water sources of district Nowshehra, Khyber Pakhtunkhwa, Pakistan. J Toxicol Environ Health A (2013) 0.75