Dirk Troost

Author PubWeight™ 71.53‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors. Hum Mutat 2009 7.68
2 Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features. PLoS One 2008 5.86
3 Familial amyotrophic lateral sclerosis with frontotemporal dementia is linked to a locus on chromosome 9p13.2-21.3. Brain 2006 5.36
4 TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions. Am J Pathol 2007 5.02
5 Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies. Acta Neuropathol 2009 2.76
6 The prognostic IDH1( R132 ) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma. Acta Neuropathol 2010 1.80
7 Dipeptide repeat protein pathology in C9ORF72 mutation cases: clinico-pathological correlations. Acta Neuropathol 2013 1.59
8 T-cell-mediated inflammatory activity in the stellate ganglia of patients with ion-channel disease and severe ventricular arrhythmias. Circ Arrhythm Electrophysiol 2014 1.45
9 Expression and functional role of mGluR3 and mGluR5 in human astrocytes and glioma cells: opposite regulation of glutamate transporter proteins. Eur J Neurosci 2003 1.44
10 Global democratic consensus on neuropathological disease criteria. Lancet Neurol 2002 1.44
11 OTX1 and OTX2 expression correlates with the clinicopathologic classification of medulloblastomas. J Neuropathol Exp Neurol 2006 1.39
12 Pontocerebellar hypoplasia type 2: a neuropathological update. Acta Neuropathol 2007 1.32
13 Expression and distribution of id helix-loop-helix proteins in human astrocytic tumors. Glia 2002 1.20
14 Astrocytes produce interferon-alpha and CXCL10, but not IL-6 or CXCL8, in Aicardi-Goutières syndrome. Glia 2008 1.18
15 Expression and cellular distribution of multidrug resistance-related proteins in the hippocampus of patients with mesial temporal lobe epilepsy. Epilepsia 2004 1.17
16 Diffuse cerebral intravascular coagulation and cerebral infarction in pneumococcal meningitis. Neurocrit Care 2010 1.16
17 Localization of breast cancer resistance protein (BCRP) in microvessel endothelium of human control and epileptic brain. Epilepsia 2005 1.12
18 Gene expression analysis of tuberous sclerosis complex cortical tubers reveals increased expression of adhesion and inflammatory factors. Brain Pathol 2009 1.12
19 Characterization of a pneumococcal meningitis mouse model. BMC Infect Dis 2012 1.11
20 Current perspectives on antiangiogenesis strategies in the treatment of malignant gliomas. Brain Res Brain Res Rev 2004 1.08
21 The membrane attack complex of the complement system is essential for rapid Wallerian degeneration. J Neurosci 2007 1.05
22 Clinicopathological and immunohistochemical findings in an autopsy case of tuberous sclerosis complex. Neuropathology 2008 0.99
23 Decrease of Hsp25 protein expression precedes degeneration of motoneurons in ALS-SOD1 mice. Eur J Neurosci 2004 0.97
24 Expression and cell distribution of group I and group II metabotropic glutamate receptor subtypes in taylor-type focal cortical dysplasia. Epilepsia 2003 0.96
25 Osteopontin is up-regulated and associated with neutrophil and macrophage infiltration in glioblastoma. Immunology 2010 0.95
26 Molecular risk stratification of medulloblastoma patients based on immunohistochemical analysis of MYC, LDHB, and CCNB1 expression. Clin Cancer Res 2008 0.94
27 Addressing diffuse glioma as a systemic brain disease with single-cell analysis. Arch Neurol 2011 0.93
28 Steroid responsive encephalopathy in cerebral amyloid angiopathy: a case report and review of evidence for immunosuppressive treatment. J Neuroinflammation 2010 0.92
29 Cellular distribution of vascular endothelial growth factor A (VEGFA) and B (VEGFB) and VEGF receptors 1 and 2 in focal cortical dysplasia type IIB. Acta Neuropathol 2008 0.92
30 Differential activity of NADPH-producing dehydrogenases renders rodents unsuitable models to study IDH1R132 mutation effects in human glioblastoma. J Histochem Cytochem 2011 0.90
31 Pi3K-mTOR signaling and AMOG expression in epilepsy-associated glioneuronal tumors. Brain Pathol 2009 0.89
32 17beta-estradiol rescues spinal motoneurons from AMPA-induced toxicity: a role for glial cells. Neurobiol Dis 2005 0.87
33 Infrequent but high-level amplification of 17p11.2 approximately p12 in human glioma. Cancer Genet Cytogenet 2003 0.87
34 Severe toxic damage to the rabbit spinal cord after intrathecal administration of preservative-free S(+)-ketamine. Anesthesiology 2006 0.86
35 Interleukin-1 beta down-regulates the expression of metabotropic glutamate receptor 5 in cultured human astrocytes. J Neuroimmunol 2005 0.85
36 Expression patterns of synaptic vesicle protein 2A in focal cortical dysplasia and TSC-cortical tubers. Epilepsia 2009 0.85
37 EXOSC3 mutations in pontocerebellar hypoplasia type 1: novel mutations and genotype-phenotype correlations. Orphanet J Rare Dis 2014 0.84
38 Mutational profiling of kinases in glioblastoma. BMC Cancer 2014 0.84
39 M. leprae components induce nerve damage by complement activation: identification of lipoarabinomannan as the dominant complement activator. Acta Neuropathol 2015 0.84
40 Expression of complement components in the peripheral nervous system. Hum Mol Genet 2003 0.83
41 Absence of AKT1 mutations in glioblastoma. PLoS One 2009 0.83
42 Inflammasome activation mediates inflammation and outcome in humans and mice with pneumococcal meningitis. BMC Infect Dis 2013 0.82
43 Overexpression of the human major vault protein in gangliogliomas. Epilepsia 2003 0.81
44 Increased expression of connective tissue growth factor in amyotrophic lateral sclerosis human spinal cord. Acta Neuropathol 2003 0.81
45 Doublecortin-like (DCL) expression in focal cortical dysplasia and cortical tubers. Epilepsia 2009 0.80
46 Expression and cellular distribution of high- and low-affinity neurotrophin receptors in malformations of cortical development. Acta Neuropathol 2004 0.80
47 Multiple meningiomas in a patient with Rubinstein-Taybi syndrome. Case report. J Neurosurg 2005 0.79
48 Expression and regulation of voltage-gated sodium channel beta1 subunit protein in human gliosis-associated pathologies. Acta Neuropathol 2003 0.78
49 Small juxtacortical hemorrhages in cerebral venous thrombosis. Ann Neurol 2014 0.78
50 Anti-aquaporin 4 related paraneoplastic neuromyelitis optica in the presence of adenocarcinoma of the lung. Clin Neuropathol 2015 0.77
51 Hydrocephalus in cerebral venous thrombosis. J Neurol 2015 0.75
52 Angiogenesis inhibitor DC101 delays growth of intracerebral glioblastoma but induces morbidity when combined with irradiation. Cancer Lett 2009 0.75
53 A remarkable pattern of subcortical vessel wall enhancement in granulomatous angiitis of the central nervous system. J Rheumatol 2012 0.75
54 The diagnostic pitfall of infratentorial subdural empyema. Arch Neurol 2012 0.75
55 Accumulation of STIM1 is associated with the degenerative muscle fibre phenotype in ALS and other neurogenic atrophies. Neuropathol Appl Neurobiol 2015 0.75
56 Recurring intracranial malignant peripheral nerve sheath tumor: case report and systematic review of the literature. Neurosurgery 2011 0.75
57 Congenital vascular malformations--cerebral lesions differ from extracranial lesions by their immune expression of the glucose transporter protein GLUT1. Clin Neuropathol 2012 0.75