Published in Tissue Eng Part A on May 15, 2012
Development of 3D hydrogel culture systems with on-demand cell separation. Biotechnol J (2013) 0.90
Adiponectin regulates bone marrow mesenchymal stem cell niche through a unique signal transduction pathway: an approach for treating bone disease in diabetes. Stem Cells (2015) 0.88
Induction of Osteogenic Differentiation in Human Mesenchymal Stem Cells by Crosstalk with Osteoblasts. Biores Open Access (2015) 0.82
Interactions between mesenchymal stem cells, adipocytes, and osteoblasts in a 3D tri-culture model of hyperglycemic conditions in the bone marrow microenvironment. Integr Biol (Camb) (2014) 0.79
Opportunities and challenges in three-dimensional brown adipogenesis of stem cells. Biotechnol Adv (2015) 0.76
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol (2002) 82.19
Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Dev Cell (2004) 16.89
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature (2010) 15.28
Amplification efficiency: linking baseline and bias in the analysis of quantitative PCR data. Nucleic Acids Res (2009) 9.64
Capturing complex 3D tissue physiology in vitro. Nat Rev Mol Cell Biol (2006) 8.81
Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell (2010) 6.24
Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate. Nat Mater (2010) 5.36
Designing materials to direct stem-cell fate. Nature (2009) 4.86
Complexity in biomaterials for tissue engineering. Nat Mater (2009) 4.38
An extracellular matrix microarray for probing cellular differentiation. Nat Methods (2005) 4.35
Identification of a subpopulation of rapidly self-renewing and multipotential adult stem cells in colonies of human marrow stromal cells. Proc Natl Acad Sci U S A (2001) 4.07
Mesenchymal stromal cells. Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation. Arthritis Res Ther (2007) 3.97
Measurement of mechanical tractions exerted by cells in three-dimensional matrices. Nat Methods (2010) 3.35
Synthetic hydrogel niches that promote hMSC viability. Matrix Biol (2005) 2.61
Adipocyte differentiation of bone marrow-derived mesenchymal stem cells: cross talk with the osteoblastogenic program. Cell Mol Life Sci (2009) 2.35
Marrow fat and the bone microenvironment: developmental, functional, and pathological implications. Crit Rev Eukaryot Gene Expr (2009) 2.26
A compendium of signals and responses triggered by prodeath and prosurvival cytokines. Mol Cell Proteomics (2005) 2.20
Photolithographic patterning of polyethylene glycol hydrogels. Biomaterials (2005) 2.20
Stem cell paracrine actions and tissue regeneration. Regen Med (2010) 1.99
Patterning network structure to spatially control cellular remodeling and stem cell fate within 3-dimensional hydrogels. Biomaterials (2010) 1.95
Microfabricated tissue gauges to measure and manipulate forces from 3D microtissues. Proc Natl Acad Sci U S A (2009) 1.89
Cytoskeleton-based forecasting of stem cell lineage fates. Proc Natl Acad Sci U S A (2009) 1.68
Instability of standard PCR reference genes in adipose-derived stem cells during propagation, differentiation and hypoxic exposure. BMC Mol Biol (2008) 1.41
Osteoblasts directly control lineage commitment of mesenchymal progenitor cells through Wnt signaling. J Biol Chem (2007) 1.37
"Mesenchymal" stem cells in human bone marrow (skeletal stem cells): a critical discussion of their nature, identity, and significance in incurable skeletal disease. Hum Gene Ther (2010) 1.37
Specific lineage-priming of bone marrow mesenchymal stem cells provides the molecular framework for their plasticity. Stem Cells (2009) 1.37
Stem cells: roadmap to the clinic. J Clin Invest (2010) 1.27
Developmental engineering: a new paradigm for the design and manufacturing of cell-based products. Part I: from three-dimensional cell growth to biomimetics of in vivo development. Tissue Eng Part B Rev (2009) 1.26
Cyclic tensile culture promotes fibroblastic differentiation of marrow stromal cells encapsulated in poly(ethylene glycol)-based hydrogels. Tissue Eng Part A (2010) 1.02
Human osteoblasts derived from mesenchymal stem cells express adipogenic markers upon coculture with bone marrow adipocytes. Differentiation (2010) 0.95
Conditioned media cause increases in select osteogenic and adipogenic differentiation markers in mesenchymal stem cell cultures. J Tissue Eng Regen Med (2008) 0.95
Regenerative medicine: then and now--an update of recent history into future possibilities. J Cell Mol Med (2010) 0.90
Enzymatically degradable poly(ethylene glycol) based hydrogels for adipose tissue engineering. Biomaterials (2010) 0.89
Uncovering the behaviors of individual cells within a multicellular microvascular community. Proc Natl Acad Sci U S A (2011) 0.88
Predicting cytotoxic T-cell age from multivariate analysis of static and dynamic biomarkers. Mol Cell Proteomics (2010) 0.88
Long-term spatially defined coculture within three-dimensional photopatterned hydrogels. Tissue Eng Part C Methods (2010) 0.85
Size-dependent release of fluorescent macromolecules and nanoparticles from radically cross-linked hydrogels. Eur J Pharm Biopharm (2009) 0.81
Oxygen sensation and social feeding mediated by a C. elegans guanylate cyclase homologue. Nature (2004) 5.09
Pathogenic bacteria induce aversive olfactory learning in Caenorhabditis elegans. Nature (2005) 4.30
Automated on-chip rapid microscopy, phenotyping and sorting of C. elegans. Nat Methods (2008) 3.34
Real-time multimodal optical control of neurons and muscles in freely behaving Caenorhabditis elegans. Nat Methods (2011) 2.19
Injectable biodegradable hydrogel composites for rabbit marrow mesenchymal stem cell and growth factor delivery for cartilage tissue engineering. Biomaterials (2007) 1.78
Delivery of TGF-beta1 and chondrocytes via injectable, biodegradable hydrogels for cartilage tissue engineering applications. Biomaterials (2005) 1.63
MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation. J Clin Invest (2013) 1.49
Engineering orthopedic tissue interfaces. Tissue Eng Part B Rev (2009) 1.45
Computer-enhanced high-throughput genetic screens of C. elegans in a microfluidic system. Lab Chip (2008) 1.44
A model of redox kinetics implicates the thiol proteome in cellular hydrogen peroxide responses. Antioxid Redox Signal (2010) 1.38
Microfluidics for the analysis of behavior, nerve regeneration, and neural cell biology in C. elegans. Curr Opin Neurobiol (2009) 1.28
A naturally derived cardiac extracellular matrix enhances cardiac progenitor cell behavior in vitro. Acta Biomater (2012) 1.27
Long-term high-resolution imaging and culture of C. elegans in chip-gel hybrid microfluidic device for developmental studies. Lab Chip (2010) 1.27
Autonomous screening of C. elegans identifies genes implicated in synaptogenesis. Nat Methods (2012) 1.26
Microfluidics-enabled phenotyping, imaging, and screening of multicellular organisms. Lab Chip (2010) 1.21
Imaging single-cell signaling dynamics with a deterministic high-density single-cell trap array. Anal Chem (2011) 1.21
Effect of dual growth factor delivery on chondrogenic differentiation of rabbit marrow mesenchymal stem cells encapsulated in injectable hydrogel composites. J Biomed Mater Res A (2009) 1.18
Effect of swelling ratio of injectable hydrogel composites on chondrogenic differentiation of encapsulated rabbit marrow mesenchymal stem cells in vitro. Biomacromolecules (2009) 1.18
Osteogenic differentiation of rat bone marrow stromal cells cultured on Arg-Gly-Asp modified hydrogels without dexamethasone and beta-glycerol phosphate. Biomaterials (2005) 1.17
Dynamics of muscle glycogenolysis modeled with pH time course computation and pH-dependent reaction equilibria and enzyme kinetics. Biophys J (2006) 1.17
High-throughput study of synaptic transmission at the neuromuscular junction enabled by optogenetics and microfluidics. J Neurosci Methods (2010) 1.15
Biological properties of dehydrated human amnion/chorion composite graft: implications for chronic wound healing. Int Wound J (2013) 1.15
Adhesion strength-based, label-free isolation of human pluripotent stem cells. Nat Methods (2013) 1.12
Gene regulation by MAPK substrate competition. Dev Cell (2011) 1.12
Repair of osteochondral defects with hyaluronan- and polyester-based scaffolds. Osteoarthritis Cartilage (2005) 1.11
Optogenetic analysis of a nociceptor neuron and network reveals ion channels acting downstream of primary sensors. Curr Biol (2012) 1.09
Reactive polymer coatings: a first step toward surface engineering of microfluidic devices. Anal Chem (2003) 1.06
Automated high-throughput cell microsurgery on-chip. Lab Chip (2009) 1.05
Dietary fat content and fiber type modulate hind gut microbial community and metabolic markers in the pig. PLoS One (2013) 1.03
Pattern formation by graded and uniform signals in the early Drosophila embryo. Biophys J (2012) 1.03
Cyclic tensile culture promotes fibroblastic differentiation of marrow stromal cells encapsulated in poly(ethylene glycol)-based hydrogels. Tissue Eng Part A (2010) 1.02
Kinetics of gene derepression by ERK signaling. Proc Natl Acad Sci U S A (2013) 1.02
Laterally orienting C. elegans using geometry at microscale for high-throughput visual screens in neurodegeneration and neuronal development studies. PLoS One (2012) 1.01
Microfluidics as a tool for C. elegans research. WormBook (2013) 1.01
Bending amplitude - a new quantitative assay of C. elegans locomotion: identification of phenotypes for mutants in genes encoding muscle focal adhesion components. Methods (2011) 1.00
Rapid and permanent neuronal inactivation in vivo via subcellular generation of reactive oxygen with the use of KillerRed. Cell Rep (2013) 0.98
Microfluidic trap array for massively parallel imaging of Drosophila embryos. Nat Protoc (2013) 0.98
A multispectral optical illumination system with precise spatiotemporal control for the manipulation of optogenetic reagents. Nat Protoc (2012) 0.97
In vitro cytotoxicity of unsaturated oligo[poly(ethylene glycol) fumarate] macromers and their cross-linked hydrogels. Biomacromolecules (2003) 0.96
PEG-based hydrogels with tunable degradation characteristics to control delivery of marrow stromal cells for tendon overuse injuries. Acta Biomater (2010) 0.96
Dynamic immune cell accumulation during flow-induced atherogenesis in mouse carotid artery: an expanded flow cytometry method. Arterioscler Thromb Vasc Biol (2012) 0.93
A computational statistics approach for estimating the spatial range of morphogen gradients. Development (2011) 0.93
Techniques for biological characterization of tissue-engineered tendon and ligament. Biomaterials (2006) 0.93
C.L.I.P.--continuous live imaging platform for direct observation of C. elegans physiological processes. Lab Chip (2013) 0.93
On-demand optical immobilization of Caenorhabditis elegans for high-resolution imaging and microinjection. Lab Chip (2014) 0.93
Epi-allelic Erk1 and Erk2 knockdown series for quantitative analysis of T cell Erk regulation and IL-2 production. Mol Immunol (2007) 0.92
Gene expression signatures of extracellular matrix and growth factors during embryonic stem cell differentiation. PLoS One (2012) 0.92
A conserved role for atlastin GTPases in regulating lipid droplet size. Cell Rep (2013) 0.91
Microbial light-activatable proton pumps as neuronal inhibitors to functionally dissect neuronal networks in C. elegans. PLoS One (2012) 0.91
Microfluidic-based generation of size-controlled, biofunctionalized synthetic polymer microgels for cell encapsulation. Adv Mater (2014) 0.90
Development of 3D hydrogel culture systems with on-demand cell separation. Biotechnol J (2013) 0.90
α-actinin is required for the proper assembly of Z-disk/focal-adhesion-like structures and for efficient locomotion in Caenorhabditis elegans. J Mol Biol (2010) 0.89
Predicting cytotoxic T-cell age from multivariate analysis of static and dynamic biomarkers. Mol Cell Proteomics (2010) 0.88
RTK signaling modulates the Dorsal gradient. Development (2012) 0.87
Microfluidic tools for developmental studies of small model organisms--nematodes, fruit flies, and zebrafish. Biotechnol J (2012) 0.87
A high-throughput device for size based separation of C. elegans developmental stages. Lab Chip (2014) 0.87
Spatial pattern dynamics of 3D stem cell loss of pluripotency via rules-based computational modeling. PLoS Comput Biol (2013) 0.86
A generalizable, tunable microfluidic platform for delivering fast temporally varying chemical signals to probe single-cell response dynamics. Anal Chem (2014) 0.86
Continuously perfused, non-cross-contaminating microfluidic chamber array for studying cellular responses to orthogonal combinations of matrix and soluble signals. Lab Chip (2009) 0.86
The effect of desulfation of chondroitin sulfate on interactions with positively charged growth factors and upregulation of cartilaginous markers in encapsulated MSCs. Biomaterials (2013) 0.86
Multiplex pressure measurement in microsystems using volume displacement of particle suspensions. Lab Chip (2009) 0.86
Development of nano- and microscale chondroitin sulfate particles for controlled growth factor delivery. Acta Biomater (2010) 0.86
Differentiation of mesenchymal stem cells in heparin-containing hydrogels via coculture with osteoblasts. Cell Tissue Res (2011) 0.85
Microfluidic-based patterning of embryonic stem cells for in vitro development studies. Lab Chip (2013) 0.85
Long-term spatially defined coculture within three-dimensional photopatterned hydrogels. Tissue Eng Part C Methods (2010) 0.85
The role of RhoC in epithelial-to-mesenchymal transition of ovarian carcinoma cells. BMC Cancer (2014) 0.85
Degradative properties and cytocompatibility of a mixed-mode hydrogel containing oligo[poly(ethylene glycol)fumarate] and poly(ethylene glycol)dithiol. Acta Biomater (2008) 0.83
Development and characterization of enhanced green fluorescent protein and luciferase expressing cell line for non-destructive evaluation of tissue engineering constructs. Biomaterials (2004) 0.83
PKN-1, a homologue of mammalian PKN, is involved in the regulation of muscle contraction and force transmission in C. elegans. J Mol Biol (2011) 0.82
Modulation of mesenchymal stem cell shape in enzyme-sensitive hydrogels is decoupled from upregulation of fibroblast markers under cyclic tension. Tissue Eng Part A (2012) 0.82
Effects of L-malic acid on alpha-glucosidase: inhibition kinetics and computational molecular dynamics simulations. Appl Biochem Biotechnol (2014) 0.82
Three-dimensional in situ temperature measurement in microsystems using Brownian motion of nanoparticles. Anal Chem (2009) 0.81
Hydrogel-droplet microfluidic platform for high-resolution imaging and sorting of early larval Caenorhabditis elegans. Lab Chip (2015) 0.81
In vivo neuron-wide analysis of synaptic vesicle precursor trafficking. Traffic (2014) 0.81
Aggregation of bovine anterior cruciate ligament fibroblasts or marrow stromal cells promotes aggrecan production. Biotechnol Bioeng (2011) 0.81
Parallel multi-time point cell stimulation and lysis on-chip for studying early signaling events in T cell activation. Lab Chip (2008) 0.81
Enabling systems biology approaches through microfabricated systems. Anal Chem (2013) 0.80
A switching mechanism in doxorubicin bioactivation can be exploited to control doxorubicin toxicity. PLoS Comput Biol (2011) 0.80
Does antigen-specific cytokine response correlate with the experience of oculorespiratory syndrome after influenza vaccine? J Infect Dis (2003) 0.79
Interactions between mesenchymal stem cells, adipocytes, and osteoblasts in a 3D tri-culture model of hyperglycemic conditions in the bone marrow microenvironment. Integr Biol (Camb) (2014) 0.79
An automated programmable platform enabling multiplex dynamic stimuli delivery and cellular response monitoring for high-throughput suspension single-cell signaling studies. Lab Chip (2015) 0.79
Association between hyperuricemia and hypertension in a Chinese population at a high risk of hypertension. Blood Press (2009) 0.79
Quantitative screening of genes regulating tryptophan hydroxylase transcription in Caenorhabditis elegans using microfluidics and an adaptive algorithm. Integr Biol (Camb) (2013) 0.79
Fluorescent coumarin thiols measure biological redox couples. Org Lett (2012) 0.79
Rabx-5 regulates RAB-5 early endosomal compartments and synaptic vesicles in C. elegans. PLoS One (2012) 0.78
Retracted Molecular basis underlying inhibition of metastasis of gastric cancer by anti-VEGFa treatment. Tumour Biol (2014) 0.78
Nitric oxide production and its functional link with OIPK in tobacco defense response elicited by chitooligosaccharide. Plant Cell Rep (2011) 0.78
Effect of selective heparin desulfation on preservation of bone morphogenetic protein-2 bioactivity after thermal stress. Bioconjug Chem (2015) 0.78
Homopolymer vesicles with a gradient bilayer membrane as drug carriers. Chem Commun (Camb) (2013) 0.78
Water-dispersible and biodegradable polymer micelles with good antibacterial efficacy. Chem Commun (Camb) (2012) 0.78