Negative argininosuccinate synthetase expression in melanoma tumours may predict clinical benefit from arginine-depleting therapy with pegylated arginine deiminase.

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Published in Br J Cancer on April 24, 2012

Authors

L G Feun1, A Marini, G Walker, G Elgart, F Moffat, S E Rodgers, C J Wu, M You, M Wangpaichitr, M T Kuo, W Sisson, A A Jungbluth, J Bomalaski, N Savaraj

Author Affiliations

1: Sylvester Comprehensive Cancer Center, University of Miami, FL 33136, USA. lfeun@med.miami.edu

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[Cutaneous leishmaniasis]. Hautarzt (2008) 1.13

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