Published in Eur J Biochem on May 01, 2003
Role of TNF-alpha in vascular dysfunction. Clin Sci (Lond) (2009) 2.06
Arginine deiminase as a novel therapy for prostate cancer induces autophagy and caspase-independent apoptosis. Cancer Res (2009) 1.88
Arginine deprivation as a targeted therapy for cancer. Curr Pharm Des (2008) 1.82
Spatial mapping of protein abundances in the mouse brain by voxelation integrated with high-throughput liquid chromatography-mass spectrometry. Genome Res (2007) 1.46
Angiotensin-converting enzyme inhibitors of Bothrops jararaca snake venom affect the structure of mice seminiferous epithelium. J Venom Anim Toxins Incl Trop Dis (2015) 1.38
Resistance to arginine deiminase treatment in melanoma cells is associated with induced argininosuccinate synthetase expression involving c-Myc/HIF-1alpha/Sp4. Mol Cancer Ther (2009) 1.37
Pancreatic cancer cell lines deficient in argininosuccinate synthetase are sensitive to arginine deprivation by arginine deiminase. Int J Cancer (2008) 1.36
Arginine deprivation, autophagy, apoptosis (AAA) for the treatment of melanoma. Curr Mol Med (2010) 1.21
Targeting arginine-dependent cancers with arginine-degrading enzymes: opportunities and challenges. Cancer Res Treat (2013) 1.13
Targeted cellular metabolism for cancer chemotherapy with recombinant arginine-degrading enzymes. Oncotarget (2010) 1.09
Restructuring of the dinucleotide-binding fold in an NADP(H) sensor protein. Proc Natl Acad Sci U S A (2007) 1.08
Negative argininosuccinate synthetase expression in melanoma tumours may predict clinical benefit from arginine-depleting therapy with pegylated arginine deiminase. Br J Cancer (2012) 1.06
Proteomic expression analysis of surgical human colorectal cancer tissues: up-regulation of PSB7, PRDX1, and SRP9 and hypoxic adaptation in cancer. J Proteome Res (2008) 1.04
Arginine starvation impairs mitochondrial respiratory function in ASS1-deficient breast cancer cells. Sci Signal (2014) 1.01
The relationship of arginine deprivation, argininosuccinate synthetase and cell death in melanoma. Drug Target Insights (2007) 0.96
The combination of ADI-PEG20 and TRAIL effectively increases cell death in melanoma cell lines. Biochem Biophys Res Commun (2010) 0.92
Argininosuccinate synthetase is a functional target for a snake venom anti-hypertensive peptide: role in arginine and nitric oxide production. J Biol Chem (2009) 0.91
Leishmania donovani argininosuccinate synthase is an active enzyme associated with parasite pathogenesis. PLoS Negl Trop Dis (2012) 0.89
Strategies for optimizing the serum persistence of engineered human arginase I for cancer therapy. J Control Release (2011) 0.87
Interactions between the NO-citrulline cycle and brain-derived neurotrophic factor in differentiation of neural stem cells. J Biol Chem (2012) 0.86
Liver proteomics in progressive alcoholic steatosis. Toxicol Appl Pharmacol (2012) 0.85
Combined lysosomal protein transmembrane 4 beta-35 and argininosuccinate synthetase expression predicts clinical outcome in hepatocellular carcinoma patients. Surg Today (2011) 0.84
Targeting Cancer Metabolism: Dietary and Pharmacologic Interventions. Cancer Discov (2016) 0.82
L-citrulline-malate influence over branched chain amino acid utilization during exercise. Eur J Appl Physiol (2010) 0.81
Increased mitochondrial arginine metabolism supports bioenergetics in asthma. J Clin Invest (2016) 0.81
Arthritis suppression by NADPH activation operates through an interferon-beta pathway. BMC Biol (2007) 0.80
ASS and SULT2A1 are Novel and Sensitive Biomarkers of Acute Hepatic Injury-A Comparative Study in Animal Models. J Liver (2013) 0.79
Down-regulation of argininosuccinate synthetase is associated with cisplatin resistance in hepatocellular carcinoma cell lines: implications for PEGylated arginine deiminase combination therapy. BMC Cancer (2014) 0.79
Pharmacodynamic modeling of acute and chronic effects of methylprednisolone on hepatic urea cycle genes in rats. Gene Regul Syst Bio (2008) 0.79
Reduced expression of ASS is closely related to clinicopathological features and post-resectional survival of hepatocellular carcinoma. Oncol Lett (2010) 0.78
Molecular characterization of argininosuccinate synthase and argininosuccinate lyase from the liver of the African lungfish Protopterus annectens, and their mRNA expression levels in the liver, kidney, brain and skeletal muscle during aestivation. J Comp Physiol B (2014) 0.78
Cytokines Modulate the "Immune-Metabolism" Interactions during Behçet Disease: Effect on Arginine Metabolism. Int J Inflam (2015) 0.78
L-citrulline supplementation reverses the impaired airway relaxation in neonatal rats exposed to hyperoxia. Respir Res (2012) 0.77
Partial deletion of argininosuccinate synthase protects from pyrazole plus lipopolysaccharide-induced liver injury by decreasing nitrosative stress. Am J Physiol Gastrointest Liver Physiol (2011) 0.77
Coagulase-negative Staphylococci favor conversion of arginine into ornithine despite a widespread genetic potential for nitric oxide synthase activity. Appl Environ Microbiol (2014) 0.77
Blood pressure follows the kidney: Perinatal influences on hereditary hypertension. Organogenesis (2008) 0.77
Hepatocyte selection medium eliminating induced pluripotent stem cells among primary human hepatocytes. World J Methodol (2015) 0.77
Identification and characterization of genes involved in leishmania pathogenesis: the potential for drug target selection. Mol Biol Int (2011) 0.77
A transgenic approach to study argininosuccinate synthetase gene expression. J Biomed Sci (2014) 0.76
Differential expression of argininosuccinate synthetase in serous and non-serous ovarian carcinomas. J Pathol Clin Res (2014) 0.76
Ethanol plus the Jo2 Fas agonistic antibody-induced liver injury is attenuated in mice with partial ablation of argininosuccinate synthase. Alcohol Clin Exp Res (2013) 0.75
Genetic Manipulation of Leishmania donovani to Explore the Involvement of Argininosuccinate Synthase in Oxidative Stress Management. PLoS Negl Trop Dis (2016) 0.75
Co-application of canavanine and irradiation uncouples anticancer potential of arginine deprivation from citrulline availability. Oncotarget (2016) 0.75
Reduced expression of argininosuccinate synthetase 1 has a negative prognostic impact in patients with pancreatic ductal adenocarcinoma. PLoS One (2017) 0.75
Proteomic and Physiological Analysis of the Response of Oat (Avena sativa) Seeds to Heat Stress under Different Moisture Conditions. Front Plant Sci (2016) 0.75
Metabolic reprogramming in clear cell renal cell carcinoma. Nat Rev Nephrol (2017) 0.75
Does Citrulline Have Protective Effects on Liver Injury in Septic Rats? Biomed Res Int (2016) 0.75
Expression profile and down-regulation of argininosuccinate synthetase in hepatocellular carcinoma in a transgenic mouse model. J Biomed Sci (2015) 0.75
L-Canavanine potentiates the cytotoxicity of doxorubicin and cisplatin in arginine deprived human cancer cells. PeerJ (2016) 0.75
Reversal of endothelial dysfunction in aorta of streptozotocin-nicotinamide-induced type-2 diabetic rats by S-Allylcysteine. Mol Cell Biochem (2017) 0.75
Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis. Curr Biol (2002) 2.73
Intraadrenal corticotropin in bilateral macronodular adrenal hyperplasia. N Engl J Med (2013) 2.66
Control of mammalian gene expression by amino acids, especially glutamine. FEBS J (2009) 1.13
Autophagosome maturation is impaired in Fabry disease. Autophagy (2010) 1.04
Glutamine stimulates argininosuccinate synthetase gene expression through cytosolic O-glycosylation of Sp1 in Caco-2 cells. J Biol Chem (2003) 0.99
Osmotic stress, a proinflammatory signal in Caco-2 cells. Biochimie (2004) 0.98
Methotrexate induces intestinal mucositis and alters gut protein metabolism independently of reduced food intake. Am J Physiol Endocrinol Metab (2008) 0.94
Glutamine and interleukin-1beta interact at the level of Sp1 and nuclear factor-kappaB to regulate argininosuccinate synthetase gene expression. FEBS J (2007) 0.93
IL-1beta stimulates argininosuccinate synthetase gene expression through NF-kappaB in Caco-2 cells. Biochimie (2005) 0.92
Immunoassay for human serum hemojuvelin. Haematologica (2010) 0.89
Enteral glutamine stimulates protein synthesis and decreases ubiquitin mRNA level in human gut mucosa. Am J Physiol Gastrointest Liver Physiol (2003) 0.87
ACTH-independent Cushing's syndrome with bilateral micronodular adrenal hyperplasia and ectopic adrenocortical adenoma. J Clin Endocrinol Metab (2009) 0.86
Is heparin plasma suitable for the determination of B-type natriuretic peptide on the Beckman-Coulter Access 2? Clin Chem Lab Med (2010) 0.86
Effects of essential amino acids or glutamine deprivation on intestinal permeability and protein synthesis in HCT-8 cells: involvement of GCN2 and mTOR pathways. Amino Acids (2010) 0.84
Hemojuvelin: a new link between obesity and iron homeostasis. Obesity (Silver Spring) (2011) 0.84
Serum hepcidin levels and muscle iron proteins in humans injected with low- or high-dose erythropoietin. Eur J Haematol (2013) 0.83
Enteral delivery of proteins stimulates protein synthesis in human duodenal mucosa in the fed state through a mammalian target of rapamycin-independent pathway. Am J Clin Nutr (2013) 0.83
Amino acid control of the human glyceraldehyde 3-phosphate dehydrogenase gene transcription in hepatocyte. Am J Physiol Gastrointest Liver Physiol (2003) 0.82
High levels of soluble serum hemojuvelin in patients with congenital dyserythropoietic anemia type I. Eur J Haematol (2012) 0.81
Influence of leucine on protein metabolism, phosphokinase expression, and cell proliferation in human duodenum1,3. Am J Clin Nutr (2011) 0.81
A diet containing whey protein, glutamine, and TGFbeta modulates gut protein metabolism during chemotherapy-induced mucositis in rats. Dig Dis Sci (2009) 0.80
NO-dependent protective effect of VEGF against excitotoxicity on layer VI of the developing cerebral cortex. Neurobiol Dis (2011) 0.78
Age-dependent neonatal intracerebral hemorrhage in plasminogen activator inhibitor 1 knockout mice. J Neuropathol Exp Neurol (2014) 0.78
Influence of garlic or its main active component diallyl disulfide on iron bioavailability and toxicity. Nutr Res (2010) 0.77
Glutamine induces nuclear degradation of the NF-κB p65 subunit in Caco-2/TC7 cells. Biochimie (2011) 0.77
3-MA inhibits autophagy and favors long-term integration of grafted Gad67-GFP GABAergic precursors in the developing neocortex by preventing apoptosis. Cell Transplant (2013) 0.76
Age-dependent alterations of the NMDA receptor developmental profile and adult behavior in postnatally ketamine-treated mice. Dev Neurobiol (2014) 0.76
Combined enteral infusion of glutamine, carbohydrates, and antioxidants modulates gut protein metabolism in humans. Am J Clin Nutr (2008) 0.76
Effects of an enteral glucose supply on protein synthesis, proteolytic pathways, and proteome in human duodenal mucosa. Am J Clin Nutr (2011) 0.75
Lack of effect of acute enteral arginine infusion on whole-body and intestinal protein metabolism in humans. Dig Dis Sci (2007) 0.75
Obesity does not influence hepcidin and hemojuvelin levels in hemodialysis patients. Nephron Clin Pract (2013) 0.75
Liver mass in a young adult. Lancet (2011) 0.75
[Non invasive assessment of liver fibrosis: guidelines of the French National Authority for health and comments of the working group "Biological markers of liver fibrosis" of the French Society of Clinical Biology]. Ann Biol Clin (Paris) (2007) 0.75
Cardiac troponin level above the 99th percentile in patients hospitalized for chest pain without any cardiac pathology detectable with paraclinical examination. Ann Clin Biochem (2004) 0.75
Biphasic effect of IL-1beta on the activity of argininosuccinate synthetase in Caco-2 cells. Involvement of nitric oxide production. Biochimie (2005) 0.75
[Detecting a peak in fraction beta by capillary electrophoresis: interference due to iomeprol]. Ann Biol Clin (Paris) (2013) 0.75