1
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Common polygenic variation contributes to risk of schizophrenia and bipolar disorder.
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Nature
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2009
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33.26
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2
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Heritability in the genomics era--concepts and misconceptions.
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Nat Rev Genet
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2008
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13.42
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3
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Estimating missing heritability for disease from genome-wide association studies.
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Am J Hum Genet
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2011
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8.95
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4
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A versatile gene-based test for genome-wide association studies.
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Am J Hum Genet
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2010
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8.44
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5
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Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.
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Nat Genet
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2013
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8.02
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6
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Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
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Nat Genet
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2013
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7.44
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7
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A mega-analysis of genome-wide association studies for major depressive disorder.
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Mol Psychiatry
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2012
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6.34
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8
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Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs.
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Nat Genet
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2012
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5.78
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9
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Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease risk.
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Hum Mol Genet
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2009
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3.53
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10
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Comparing apples and oranges: equating the power of case-control and quantitative trait association studies.
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Genet Epidemiol
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2010
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2.13
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11
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Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis.
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Hum Mol Genet
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2012
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1.96
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12
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Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture.
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PLoS Genet
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2013
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1.68
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13
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Estimation of SNP heritability from dense genotype data.
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Am J Hum Genet
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2013
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1.64
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14
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A better coefficient of determination for genetic profile analysis.
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Genet Epidemiol
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2012
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1.63
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15
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Estimation and partition of heritability in human populations using whole-genome analysis methods.
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Annu Rev Genet
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2013
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1.41
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16
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Seasonality shows evidence for polygenic architecture and genetic correlation with schizophrenia and bipolar disorder.
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J Clin Psychiatry
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2015
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1.40
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17
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Translation elongation factor eEF1A2 is a potential oncoprotein that is overexpressed in two-thirds of breast tumours.
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BMC Cancer
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2005
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1.33
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18
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A 3p26-3p25 genetic linkage finding for DSM-IV major depression in heavy smoking families.
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Am J Psychiatry
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2011
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1.32
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19
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Sporadic cases are the norm for complex disease.
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Eur J Hum Genet
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2009
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1.31
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20
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Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.
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Eur J Hum Genet
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2010
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1.27
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21
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Underestimated effect sizes in GWAS: fundamental limitations of single SNP analysis for dichotomous phenotypes.
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PLoS One
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2011
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1.19
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22
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A genome-wide association study of Cloninger's temperament scales: implications for the evolutionary genetics of personality.
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Biol Psychol
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2010
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1.12
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23
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Interpreting the role of de novo protein-coding mutations in neuropsychiatric disease.
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Nat Genet
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2013
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1.10
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24
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Additive genetic variation in schizophrenia risk is shared by populations of African and European descent.
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Am J Hum Genet
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2013
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1.07
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25
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Genetic and environmental influences on the co-morbidity between depression, panic disorder, agoraphobia, and social phobia: a twin study.
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Depress Anxiety
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2009
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1.07
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26
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Novel genetic analysis for case-control genome-wide association studies: quantification of power and genomic prediction accuracy.
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PLoS One
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2013
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1.02
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27
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Where GWAS and epidemiology meet: opportunities for the simultaneous study of genetic and environmental risk factors in schizophrenia.
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Schizophr Bull
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2013
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1.01
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28
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A genome-wide association study of sleep habits and insomnia.
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Am J Med Genet B Neuropsychiatr Genet
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2013
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0.98
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29
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Genetic differences between five European populations.
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Hum Hered
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2010
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0.98
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30
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Shared temperament risk factors for anorexia nervosa: a twin study.
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Psychosom Med
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2007
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0.95
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31
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Unraveling the genetic etiology of adult antisocial behavior: a genome-wide association study.
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PLoS One
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2012
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0.94
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32
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New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis.
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Int J Epidemiol
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2015
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0.93
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33
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Do 5HTTLPR and stress interact in risk for depression and suicidality? Item response analyses of a large sample.
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Am J Med Genet B Neuropsychiatr Genet
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2010
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0.92
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34
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Sex differences in symptoms of depression in unrelated individuals and opposite-sex twin and sibling pairs.
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Twin Res Hum Genet
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2006
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0.91
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35
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A recessive genetic model and runs of homozygosity in major depressive disorder.
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Am J Med Genet B Neuropsychiatr Genet
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2014
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0.91
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36
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Empirical evaluation of the genetic similarity of samples from twin registries in Australia and the Netherlands using 359 STRP markers.
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Twin Res Hum Genet
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2006
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0.89
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37
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Epigenetic Signatures of Cigarette Smoking.
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Circ Cardiovasc Genet
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2016
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0.88
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38
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Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report.
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PLoS One
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2013
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0.88
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39
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Hypermethylation in the ZBTB20 gene is associated with major depressive disorder.
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Genome Biol
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2014
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0.88
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40
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NFIB-mediated repression of the epigenetic factor Ezh2 regulates cortical development.
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J Neurosci
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2014
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0.87
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41
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Overlap of expression quantitative trait loci (eQTL) in human brain and blood.
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BMC Med Genomics
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2014
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0.87
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42
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Research review: the role of cytokines in depression in adolescents: a systematic review.
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J Child Psychol Psychiatry
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2013
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0.87
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43
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Response to Amar J. Klar: The chromosome 1;11 translocation provides the best evidence supporting genetic etiology for schizophrenia and bipolar affective disorders.
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Genetics
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2003
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0.86
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44
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Suggestive linkage on chromosome 2, 8, and 17 for lifetime major depression.
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Am J Med Genet B Neuropsychiatr Genet
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2009
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0.86
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45
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Haplotype analysis and a novel allele-sharing method refines a chromosome 4p locus linked to bipolar affective disorder.
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Biol Psychiatry
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2006
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0.85
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46
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Testing the role of circadian genes in conferring risk for psychiatric disorders.
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Am J Med Genet B Neuropsychiatr Genet
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2014
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0.84
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47
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Applying polygenic risk scores to postpartum depression.
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Arch Womens Ment Health
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2014
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0.82
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48
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Glutamate cysteine ligase (GCL) and self reported depression: an association study from the HUNT.
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J Affect Disord
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2011
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0.82
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49
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A genome wide survey supports the involvement of large copy number variants in schizophrenia with and without intellectual disability.
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Am J Med Genet B Neuropsychiatr Genet
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2013
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0.81
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50
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Assumptions and properties of limiting pathway models for analysis of epistasis in complex traits.
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PLoS One
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2013
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0.81
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51
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Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes.
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Eur J Hum Genet
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2012
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0.78
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52
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Conventional multipoint nonparametric linkage analysis is not necessarily inherently biased.
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Am J Hum Genet
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2004
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0.77
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53
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Phenotypic and discordant-monozygotic analyses of stress and perceived social support as antecedents to or sequelae of risk for depression.
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Twin Res Hum Genet
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2009
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0.75
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54
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Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS.
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Sci Transl Med
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2022
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0.75
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55
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Concepts and Misconceptions about the Polygenic Additive Model Applied to Disease.
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Hum Hered
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2016
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0.75
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56
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The epigenetic clock and telomere length are independently associated with chronological age and mortality.
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Int J Epidemiol
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2017
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0.75
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