Meinrad Busslinger

Author PubWeight™ 110.15‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors. Nature 2007 5.39
2 Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene. Genes Dev 2004 3.66
3 The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells. Immunity 2012 3.65
4 The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells. Nat Immunol 2011 3.44
5 Tlx3 and Tlx1 are post-mitotic selector genes determining glutamatergic over GABAergic cell fates. Nat Neurosci 2004 3.26
6 Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity 2007 3.19
7 A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse. Genes Dev 2008 3.16
8 Pax5: the guardian of B cell identity and function. Nat Immunol 2007 3.15
9 Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene. Nat Immunol 2004 2.90
10 Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells. Immunity 2006 2.64
11 CTCF-binding elements mediate control of V(D)J recombination. Nature 2011 2.62
12 Nephric lineage specification by Pax2 and Pax8. Genes Dev 2002 2.52
13 Mcl-1 is essential for germinal center formation and B cell memory. Science 2010 2.42
14 The distal V(H) gene cluster of the Igh locus contains distinct regulatory elements with Pax5 transcription factor-dependent activity in pro-B cells. Immunity 2011 2.41
15 Reversion of B cell commitment upon loss of Pax5 expression. Science 2002 2.16
16 Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development. Immunity 2008 2.11
17 Transcription factor Pax5 activates the chromatin of key genes involved in B cell signaling, adhesion, migration, and immune function. Immunity 2007 2.06
18 Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development. Nat Immunol 2009 2.05
19 RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci. Nat Immunol 2009 1.98
20 Pax 2/8-regulated Gata 3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney. Development 2005 1.91
21 Distinct promoters mediate the regulation of Ebf1 gene expression by interleukin-7 and Pax5. Mol Cell Biol 2006 1.81
22 Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes. Nat Immunol 2007 1.77
23 Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells. Blood 2010 1.71
24 Stepwise activation of enhancer and promoter regions of the B cell commitment gene Pax5 in early lymphopoiesis. Immunity 2009 1.67
25 Reporter gene insertions reveal a strictly B lymphoid-specific expression pattern of Pax5 in support of its B cell identity function. J Immunol 2007 1.61
26 Derivation of 2 categories of plasmacytoid dendritic cells in murine bone marrow. Blood 2005 1.58
27 Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire. Immunity 2013 1.56
28 Transcriptional control of B-cell development. Curr Opin Immunol 2002 1.51
29 The B-cell identity factor Pax5 regulates distinct transcriptional programmes in early and late B lymphopoiesis. EMBO J 2012 1.50
30 Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1. Immunity 2002 1.48
31 Control of pre-BCR signaling by Pax5-dependent activation of the BLNK gene. Immunity 2002 1.43
32 Pax5: a master regulator of B cell development and leukemogenesis. Adv Immunol 2011 1.37
33 A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis. Cancer Cell 2013 1.37
34 Hematopoietic precursor cells transiently reestablish permissiveness for X inactivation. Mol Cell Biol 2006 1.34
35 In vitro differentiation of murine embryonic stem cells toward a renal lineage. Differentiation 2007 1.31
36 Analysis of Notch1 function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors. J Immunol 2004 1.31
37 Tissue-specific expression of cre recombinase from the Pax8 locus. Genesis 2004 1.30
38 Myeloid lineage switch of Pax5 mutant but not wild-type B cell progenitors by C/EBPalpha and GATA factors. EMBO J 2003 1.29
39 Developmental plasticity of lymphocytes. Curr Opin Immunol 2008 1.29
40 Epigenetic silencing of the c-fms locus during B-lymphopoiesis occurs in discrete steps and is reversible. EMBO J 2004 1.28
41 The transcription factor Pax5 regulates its target genes by recruiting chromatin-modifying proteins in committed B cells. EMBO J 2011 1.22
42 Differential requirement for Nfil3 during NK cell development. J Immunol 2014 1.21
43 GATA-3 regulates the self-renewal of long-term hematopoietic stem cells. Nat Immunol 2013 1.19
44 STAT5 in B cell development and leukemia. Curr Opin Immunol 2010 1.19
45 B-lymphoid cells with attributes of dendritic cells regulate T cells via indoleamine 2,3-dioxygenase. Proc Natl Acad Sci U S A 2010 1.15
46 Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation. BMC Dev Biol 2010 1.12
47 Essential role of EBF1 in the generation and function of distinct mature B cell types. J Exp Med 2012 1.12
48 Corecruitment of the Grg4 repressor by PU.1 is critical for Pax5-mediated repression of B-cell-specific genes. EMBO Rep 2004 1.11
49 The activation and maintenance of Pax2 expression at the mid-hindbrain boundary is controlled by separate enhancers. Development 2002 1.04
50 Postnatal development of the murine cerebellar cortex: formation and early dispersal of basket, stellate and Golgi neurons. Eur J Neurosci 2006 1.03
51 Life beyond cleavage: the case of Ago2 and hematopoiesis. Genes Dev 2007 0.99
52 The mechanism of repression of the myeloid-specific c-fms gene by Pax5 during B lineage restriction. EMBO J 2006 0.98
53 Id2-mediated inhibition of E2A represses memory CD8+ T cell differentiation. J Immunol 2013 0.96
54 Identification of Pax2-regulated genes by expression profiling of the mid-hindbrain organizer region. Development 2005 0.95
55 Oncogenic role of Pax5 in the T-lymphoid lineage upon ectopic expression from the immunoglobulin heavy-chain locus. Blood 2006 0.95
56 Erythropoiesis and globin switching in compound Klf1::Bcl11a mutant mice. Blood 2013 0.94
57 Regulation of DNA replication within the immunoglobulin heavy-chain locus during B cell commitment. PLoS Biol 2012 0.92
58 Lack of nuclear factor-kappa B2/p100 causes a RelB-dependent block in early B lymphopoiesis. Blood 2008 0.91
59 Activation-induced cytidine deaminase expression in CD4+ T cells is associated with a unique IL-10-producing subset that increases with age. PLoS One 2011 0.89
60 Transcription factor YY1 is essential for regulation of the Th2 cytokine locus and for Th2 cell differentiation. Proc Natl Acad Sci U S A 2012 0.89
61 Reporter gene insertions reveal a strictly B lymphoid-specific expression pattern of Pax5 in support of its B cell identity function. J Immunol 2007 0.87
62 Regulation of GATA-3 expression during CD4 lineage differentiation. J Immunol 2011 0.86
63 GABAergic neurons regulate lateral ventricular development via transcription factor Pax5. Genesis 2013 0.81
64 Rapid in vivo analysis of mutant forms of the LAT adaptor using Pax5-Lat double-deficient pro-B cells. Eur J Immunol 2005 0.77
65 B young again. Immunity 2008 0.76
66 Paul Ehrlich (1854-1915) and His Contributions to the Foundation and Birth of Translational Medicine. J Innate Immun 2016 0.75
67 Pillars Article: Commitment to the B-lymphoid lineage depends on the transcription factor Pax5. Nature. 1999. 401: 556-562. J Immunol 2015 0.75
68 A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis. Cancer Cell 2016 0.75