Published in Proc Natl Acad Sci U S A on December 01, 1990
Triple helix formation inhibits transcription elongation in vitro. Proc Natl Acad Sci U S A (1991) 2.28
Measuring motion on DNA by the type I restriction endonuclease EcoR124I using triplex displacement. EMBO J (2000) 2.02
Specificity and stringency in DNA triplex formation. Proc Natl Acad Sci U S A (1991) 1.96
Formation of triple-helical structures by the 3'-end sequences of MALAT1 and MENβ noncoding RNAs. Proc Natl Acad Sci U S A (2012) 1.58
Effect of 5-methylcytosine on the stability of triple-stranded DNA--a thermodynamic study. Nucleic Acids Res (1991) 1.53
A study of oligonucleotide reassociation using large arrays of oligonucleotides synthesised on a glass support. Nucleic Acids Res (1993) 1.52
Oligonucleotide-mediated triple helix formation using an N3-protonated deoxycytidine analog exhibiting pH-independent binding within the physiological range. Proc Natl Acad Sci U S A (1992) 1.44
The contribution of DNA single-stranded order to the thermodynamics of duplex formation. Proc Natl Acad Sci U S A (1991) 1.43
Prediction of the stability of DNA triplexes. Proc Natl Acad Sci U S A (1996) 1.09
Repression of bacteriophage promoters by DNA and RNA oligonucleotides. Nucleic Acids Res (1993) 1.07
Thermodynamic and kinetic stability of intermolecular triple helices containing different proportions of C+*GC and T*AT triplets. Nucleic Acids Res (2003) 1.06
Drug binding to higher ordered DNA structures: netropsin complexation with a nucleic acid triple helix. Proc Natl Acad Sci U S A (1992) 1.05
Effects of an abasic site on triple helix formation characterized by affinity cleaving. Nucleic Acids Res (1991) 1.03
Comparative spectroscopic, calorimetric, and computational studies of nucleic acid complexes with 2',5"-versus 3',5"-phosphodiester linkages. Proc Natl Acad Sci U S A (1993) 1.02
Polyamine-linked oligonucleotides for DNA triple helix formation. Nucleic Acids Res (1993) 1.01
Ferrocene-oligonucleotide conjugates for electrochemical probing of DNA. Nucleic Acids Res (1996) 0.99
Pyrimidine phosphorothioate oligonucleotides form triple-stranded helices and promote transcription inhibition. Nucleic Acids Res (1994) 0.99
Detection and kinetic studies of triplex formation by oligodeoxynucleotides using real-time biomolecular interaction analysis (BIA). Nucleic Acids Res (1995) 0.99
UV spectroscopic identification and thermodynamic analysis of protonated third strand deoxycytidine residues at neutrality in the triplex d(C(+)-T)6:[d(A-G)6.d(C-T)6]; evidence for a proton switch. Nucleic Acids Res (1995) 0.98
A molecular anchor for stabilizing triple-helical DNA. Proc Natl Acad Sci U S A (1995) 0.93
Triplex formation with 2'-O,4'-C-ethylene-bridged nucleic acids (ENA) having C3'-endo conformation at physiological pH. Nucleic Acids Res (2003) 0.90
Triplex formation at physiological pH by 5-Me-dC-N4-(spermine) [X] oligodeoxynucleotides: non protonation of N3 in X of X*G:C triad and effect of base mismatch/ionic strength on triplex stabilities. Nucleic Acids Res (1996) 0.90
Ligand-induced formation of nucleic acid triple helices. Proc Natl Acad Sci U S A (1994) 0.90
Characteristics of triplex-directed photoadduct formation by psoralen-linked oligodeoxynucleotides. Nucleic Acids Res (1995) 0.89
6-Oxocytidine a novel protonated C-base analogue for stable triple helix formation. Nucleic Acids Res (1995) 0.86
Thermodynamic and kinetic studies of the formation of triple helices between purine-rich deoxyribo-oligonucleotides and the promoter region of the human c-src proto-oncogene. Nucleic Acids Res (1998) 0.85
Recognition of duplex DNA by RNA polynucleotides. Nucleic Acids Res (1995) 0.85
Molecular recognition via triplex formation of mixed purine/pyrimidine DNA sequences using oligoTRIPs. J Am Chem Soc (2005) 0.83
Sensitive and label-free biosensing of RNA with predicted secondary structures by a triplex affinity capture method. Nucleic Acids Res (2012) 0.81
Replication fork stalling and checkpoint activation by a PKD1 locus mirror repeat polypurine-polypyrimidine (Pu-Py) tract. J Biol Chem (2012) 0.81
Kinetics of the triplex-duplex transition in DNA. Biophys J (2012) 0.80
Conserved thermochemistry of guanosine nucleophile binding for structurally distinct group I ribozymes. Nucleic Acids Res (1996) 0.80
Sequence composition effects on the stabilities of triple helix formation by oligonucleotides containing N7-deoxyguanosine. Nucleic Acids Res (1996) 0.80
Vibrational normal modes and dynamical stability of DNA triplex poly(dA). 2poly(dT): S-type structure is more stable and in better agreement with observations in solution. Biophys J (1997) 0.78
Stability of triple-helical poly(dT)-poly(dA)-poly(dT) DNA with counterions. Biophys J (1998) 0.78
Toward site-specific, homogeneous and highly stable fluorescent silver nanoclusters fabrication on triplex DNA scaffolds. Nucleic Acids Res (2012) 0.78
Effect of DNA target sequence on triplex formation by oligo-2'-deoxy- and 2'-O-methylribonucleotides. Nucleic Acids Res (2003) 0.78
Hybridization properties of oligodeoxynucleotide pairs bridged by polyarginine peptides. Nucleic Acids Res (1996) 0.77
Comparable stability of Hoogsteen and Watson-Crick base pairs in ionic liquid choline dihydrogen phosphate. Sci Rep (2014) 0.76
Double-stranded DNA-templated cleavage of oligonucleotides containing a P3'->N5' linkage triggered by triplex formation: the effects of chemical modifications and remarkable enhancement in reactivity. Nucleic Acids Res (2010) 0.75
Dodecamer d-AGATCTAGATCT and a homologous hairpin form triplex in the presence of peptide REWER. PLoS One (2013) 0.75
A Temperature-Jump Optical Trap for Single-Molecule Manipulation. Biophys J (2015) 0.75
Structure, stability and behaviour of nucleic acids in ionic liquids. Nucleic Acids Res (2014) 0.75
Fluorescent triplex-forming DNA oligonucleotides labeled with a thiazole orange dimer unit. Artif DNA PNA XNA (2013) 0.75
Single-stranded DNA catalyzes hybridization of PCR-products to microarray capture probes. PLoS One (2014) 0.75
Predicting DNA duplex stability from the base sequence. Proc Natl Acad Sci U S A (1986) 21.73
Free energy of imperfect nucleic acid helices. II. Small hairpin loops. J Mol Biol (1973) 10.07
Sequence-specific cleavage of double helical DNA by triple helix formation. Science (1987) 9.20
Calculating thermodynamic data for transitions of any molecularity from equilibrium melting curves. Biopolymers (1987) 6.96
Studies on the formation of two- and three-stranded polyribonucleotides. Biochim Biophys Acta (1957) 5.94
Physical and chemical characterization of two- and three-stranded adenine-thymine and adenine-uracil homopolymer complexes. J Mol Biol (1966) 5.83
Structures for the polynucleotide complexes poly(dA) with poly (dT) and poly(dT) with poly(dA) with poly (dT). J Mol Biol (1974) 5.14
Inhibition of DNA binding proteins by oligonucleotide-directed triple helix formation. Science (1989) 3.88
The chemistry and biology of unusual DNA structures adopted by oligopurine.oligopyrimidine sequences. FASEB J (1988) 3.84
Specificity of the three-stranded complex formation between double-stranded DNA and single-stranded RNA containing repeating nucleotide sequences. J Mol Biol (1968) 3.53
DNA H form requires a homopurine-homopyrimidine mirror repeat. Nature (1988) 3.18
COMPLEX FORMATION BETWEEN POLYCYTIDYLIC ACID AND GUANINE OLIGONUCLEOTIDES. J Biol Chem (1964) 3.14
Sequence-specific binding and photocrosslinking of alpha and beta oligodeoxynucleotides to the major groove of DNA via triple-helix formation. Proc Natl Acad Sci U S A (1988) 2.82
Topology and formation of triple-stranded H-DNA. Science (1989) 2.81
Complexes formed by (pyrimidine)n . (purine)n DNAs on lowering the pH are three-stranded. Nucleic Acids Res (1979) 2.62
Poly(pyrimidine) . poly(purine) synthetic DNAs containing 5-methylcytosine form stable triplexes at neutral pH. Nucleic Acids Res (1984) 2.55
Sequence-specific intercalating agents: intercalation at specific sequences on duplex DNA via major groove recognition by oligonucleotide-intercalator conjugates. Proc Natl Acad Sci U S A (1989) 2.38
Triple-strand formation in the homopurine:homopyrimidine DNA oligonucleotides d(G-A)4 and d(T-C)4. Nature (1989) 2.33
Structures for Poly(U)-poly(A)-poly(U)triple stranded polynucleotides. Nat New Biol (1973) 2.20
Site-specific inhibition of EcoRI restriction/modification enzymes by a DNA triple helix. Nucleic Acids Res (1990) 2.12
Specificity in formation of triple-stranded nucleic acid helical complexes: studies with agarose-linked polyribonucleotide affinity columns. Biochemistry (1988) 2.09
Models of triple-stranded polynucleotides with optimised stereochemistry. Nucleic Acids Res (1976) 2.06
NMR studies of DNA (R+)n.(Y-)n.(Y+)n triple helices in solution: imino and amino proton markers of T.A.T and C.G.C+ base-triple formation. Biochemistry (1989) 2.00
Sequence-specific recognition and cleavage of duplex DNA via triple-helix formation by oligonucleotides covalently linked to a phenanthroline-copper chelate. Proc Natl Acad Sci U S A (1989) 1.96
Heats of the helix-coil transitions of the poly A-poly U complexes. Biopolymers (1968) 1.84
Formation of the triple-stranded polynucleotide helix, poly(A.A.U). Proc Natl Acad Sci U S A (1987) 1.79
Triple helix formation by oligopurine-oligopyrimidine DNA fragments. Electrophoretic and thermodynamic behavior. J Mol Biol (1990) 1.78
NMR studies of triple-strand formation from the homopurine-homopyrimidine deoxyribonucleotides d(GA)4 and d(TC)4. Biochemistry (1989) 1.73
Structural analysis of the (dA)10.2(dT)10 triple helix. Proc Natl Acad Sci U S A (1990) 1.69
Thermodynamic comparison of the base pairs formed by the carcinogenic lesion O6-methylguanine with reference both to Watson-Crick pairs and to mismatched pairs. Biochemistry (1989) 1.60
Polynucleotides. 8. A spectral approach to the equilibria between polyriboadenylate and polyribouridylate and their complexes. J Mol Biol (1967) 1.57
Heat of the reaction forming the three-stranded poly (A + 2U) complex. Biopolymers (1965) 1.44
MULTISTRANDED DNA HOMOPOLYMER INTERACTIONS. J Mol Biol (1964) 0.91
Predicting DNA duplex stability from the base sequence. Proc Natl Acad Sci U S A (1986) 21.73
Sequence-specific cleavage of double helical DNA by triple helix formation. Science (1987) 9.20
Calculating thermodynamic data for transitions of any molecularity from equilibrium melting curves. Biopolymers (1987) 6.96
Second structural motif for recognition of DNA by oligonucleotide-directed triple-helix formation. Science (1991) 5.40
Cleavage of DNA with methidiumpropyl-EDTA-iron(II): reaction conditions and product analyses. Biochemistry (1984) 4.20
Inhibition of DNA binding proteins by oligonucleotide-directed triple helix formation. Science (1989) 3.88
Map of distamycin, netropsin, and actinomycin binding sites on heterogeneous DNA: DNA cleavage-inhibition patterns with methidiumpropyl-EDTA.Fe(II). Proc Natl Acad Sci U S A (1982) 3.81
Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligands. Nature (1998) 3.77
Structure, dynamics, and energetics of deoxyguanosine . thymidine wobble base pair formation in the self-complementary d(CGTGAATTCGCG) duplex in solution. Biochemistry (1982) 3.76
Design of sequence-specific DNA-binding molecules. Science (1986) 3.50
Salt-dependent conformational transitions in the self-complementary deoxydodecanucleotide d(CGCAATTCGCG): evidence for hairpin formation. Biopolymers (1983) 3.44
Premelting and melting transitions in the d(CGCGAATTCGCG) self-complementary duplex in solution. Biochemistry (1982) 3.30
Thermodynamics of (dG--dC)3 double-helix formation in water and deuterium oxide. Biochemistry (1981) 3.30
Methidiumpropyl-EDTA.Fe(II) and DNase I footprinting report different small molecule binding site sizes on DNA. Nucleic Acids Res (1983) 3.18
Extra adenosine stacks into the self-complementary d(CGCAGAATTCGCG) duplex in solution. Biochemistry (1982) 3.02
Calorimetric and spectroscopic investigation of the helix-to-coil transition of a ribo-oligonucleotide: rA7U7. J Mol Biol (1975) 2.84
Sequence-specific cleavage of single-stranded DNA: oligodeoxynucleotide-EDTA X Fe(II). Proc Natl Acad Sci U S A (1985) 2.54
Echinomycin binding sites on DNA. Science (1984) 2.44
Influence of loop residues on the relative stabilities of DNA hairpin structures. Proc Natl Acad Sci U S A (1988) 2.37
Calorimetric determination of base-stacking enthalpies in double-helical DNA molecules. Biopolymers (1982) 2.36
Recognition of DNA by designed ligands at subnanomolar concentrations. Nature (1996) 2.32
Recognition of thymine adenine.base pairs by guanine in a pyrimidine triple helix motif. Science (1989) 2.28
Regulation of gene expression by small molecules. Nature (1997) 2.27
Kinetic analysis of oligodeoxyribonucleotide-directed triple-helix formation on DNA. Biochemistry (1990) 2.17
Influence of dangling thymidine residues on the stability and structure of two DNA duplexes. Biochemistry (1988) 2.16
A more unified picture for the thermodynamics of nucleic acid duplex melting: a characterization by calorimetric and volumetric techniques. Proc Natl Acad Sci U S A (1999) 2.16
Influence of the oxidatively damaged adduct 8-oxodeoxyguanosine on the conformation, energetics, and thermodynamic stability of a DNA duplex. Biochemistry (1995) 2.09
Sequence-specific recognition of double helical RNA and RNA.DNA by triple helix formation. Proc Natl Acad Sci U S A (1993) 2.07
A structural basis for recognition of A.T and T.A base pairs in the minor groove of B-DNA. Science (1998) 2.05
Thermodynamics and structure of a DNA tetraplex: a spectroscopic and calorimetric study of the tetramolecular complexes of d(TG3T) and d(TG3T2G3T). Proc Natl Acad Sci U S A (1992) 2.03
Chromomycin, mithramycin, and olivomycin binding sites on heterogeneous deoxyribonucleic acid. Footprinting with (methidiumpropyl-EDTA)iron(II). Biochemistry (1983) 2.00
Footprinting methods for analysis of pyrrole-imidazole polyamide/DNA complexes. Methods Enzymol (2001) 1.97
Calorimetric and spectroscopic investigation of drug-DNA interactions. I. The binding of netropsin to poly d(AT). Nucleic Acids Res (1983) 1.96
Sequence-specific double-strand cleavage of DNA by penta-N-methylpyrrolecarboxamide-EDTA X Fe(II). Proc Natl Acad Sci U S A (1983) 1.92
Single-site enzymatic cleavage of yeast genomic DNA mediated by triple helix formation. Nature (1991) 1.91
Spectroscopic and calorimetric characterizations of DNA duplexes containing 2-aminopurine. Biochemistry (1996) 1.88
Site-specific cleavage of a yeast chromosome by oligonucleotide-directed triple-helix formation. Science (1990) 1.84
Effect of tetramethylammonium ion on the helix-to-coil transition of poly(deoxyadenylylthymidine): a nuclear magnetic resonance and calorimetric investigation. Biochemistry (1981) 1.83
Origins of netropsin binding affinity and specificity: correlations of thermodynamic and structural data. Proc Natl Acad Sci U S A (1987) 1.83
Molecular recognition of B-DNA by Hoechst 33258. Nucleic Acids Res (1985) 1.80
The influence of single base triplet changes on the stability of a pur.pur.pyr triple helix determined by affinity cleaving. Nucleic Acids Res (1992) 1.80
Synthesis of a sequence-specific DNA-cleaving peptide. Science (1987) 1.78
Relationship between sonographic and pathologic findings in epidermal inclusion cysts. J Clin Ultrasound (2001) 1.77
Tetraplex formation of a guanine-containing nonameric DNA fragment. Science (1990) 1.75
Antiparallel side-by-side dimeric motif for sequence-specific recognition in the minor groove of DNA by the designed peptide 1-methylimidazole-2-carboxamide netropsin. Proc Natl Acad Sci U S A (1992) 1.74
Structural basis for G.C recognition in the DNA minor groove. Nat Struct Biol (1998) 1.74
Cleavage of chromatin with methidiumpropyl-EDTA . iron(II). Proc Natl Acad Sci U S A (1983) 1.71
Adenine specific DNA chemical sequencing reaction. Nucleic Acids Res (1987) 1.69
Site-specific cleavage of human chromosome 4 mediated by triple-helix formation. Science (1991) 1.67
Calorimetric and spectroscopic investigation of the helix-to-coil transition of the self-complementary deoxyribonucleotide ATGCAT. Biophys Chem (1981) 1.67
Influence of pH on the equilibrium association constants for oligodeoxyribonucleotide-directed triple helix formation at single DNA sites. Biochemistry (1992) 1.66
Distamycin and penta-N-methylpyrrolecarboxamide binding sites on native DNA. A comparison of methidiumpropyl-EDTA-Fe(II) footprinting and DNA affinity cleaving. J Biomol Struct Dyn (1984) 1.66
Analysis of promoter-specific repression by triple-helical DNA complexes in a eukaryotic cell-free transcription system. Biochemistry (1992) 1.65
Flanking sequence effects within the pyrimidine triple-helix motif characterized by affinity cleaving. Biochemistry (1992) 1.62
TMPRSS4 promotes invasion, migration and metastasis of human tumor cells by facilitating an epithelial-mesenchymal transition. Oncogene (2007) 1.58
Structure and energetics of a hexanucleotide duplex with stacked trinucleotide ends formed by the sequence d(GAATTCGCG). Biochemistry (1982) 1.53
Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands. Proc Natl Acad Sci U S A (1998) 1.50
Thermodynamic characterization of daunomycin-DNA interactions: comparison of complete binding profiles for a series of DNA host duplexes. Biochemistry (1993) 1.47
Thermodynamic consequences of an abasic lesion in duplex DNA are strongly dependent on base sequence. Biochemistry (1998) 1.44
The contribution of DNA single-stranded order to the thermodynamics of duplex formation. Proc Natl Acad Sci U S A (1991) 1.43
Activation of gene expression by small molecule transcription factors. Proc Natl Acad Sci U S A (2000) 1.40
Design of a G.C-specific DNA minor groove-binding peptide. Science (1994) 1.39
Sequence-specific recognition of DNA in the nucleosome by pyrrole-imidazole polyamides. J Mol Biol (2001) 1.39
Melting behavior of a covalently closed, single-stranded, circular DNA. Biochemistry (1989) 1.37
Solvent effects on the kinetics and thermodynamics of stacking in poly(cytidylic acid). Biochemistry (1981) 1.36
Sequence-specific recognition of B-DNA by oligo(N-methylpyrrolecarboxamide)s. Proc Natl Acad Sci U S A (1985) 1.33
Hoogsteen base pairs proximal and distal to echinomycin binding sites on DNA. Proc Natl Acad Sci U S A (1987) 1.32
Only one of the two DNA-bound orientations of AP-1 found in solution cooperates with NFATp. Curr Biol (1995) 1.32
Influence of abasic and anucleosidic sites on the stability, conformation, and melting behavior of a DNA duplex: correlations of thermodynamic and structural data. Proc Natl Acad Sci U S A (1989) 1.31
Physical studies of DNA premelting equilibria in duplexes with and without homo dA.dT tracts: correlations with DNA bending. Biochemistry (1990) 1.30
On the pairing rules for recognition in the minor groove of DNA by pyrrole-imidazole polyamides. Chem Biol (1997) 1.30
A perspective on biological catalysis. Nat Struct Biol (1996) 1.26
Targeting the minor groove of DNA. Curr Opin Struct Biol (1997) 1.25
Structural motif of the GCN4 DNA binding domain characterized by affinity cleaving. Science (1990) 1.23
Thermodynamics of drug-DNA interactions. J Biomol Struct Dyn (1983) 1.22
Magnetic resonance imaging of unroofed coronary sinus: three cases. Pediatr Cardiol (2000) 1.20
Influence of cisplatin intrastrand crosslinking on the conformation, thermal stability, and energetics of a 20-mer DNA duplex. Proc Natl Acad Sci U S A (1996) 1.20
Chemical approaches to control gene expression. Gene Expr (2000) 1.18
Binding of a hairpin polyamide in the minor groove of DNA: sequence-specific enthalpic discrimination. Proc Natl Acad Sci U S A (1996) 1.18
Thermodynamics of an intramolecular DNA triple helix: a calorimetric and spectroscopic study of the pH and salt dependence of thermally induced structural transitions. J Mol Biol (1995) 1.18
Specific recognition of CG base pairs by 2-deoxynebularine within the purine.purine.pyrimidine triple-helix motif. Biochemistry (1993) 1.18
Inhibition of Ets-1 DNA binding and ternary complex formation between Ets-1, NF-kappaB, and DNA by a designed DNA-binding ligand. J Biol Chem (1999) 1.16
Characterization of the minor groove environment in a drug-DNA complex: bisbenzimide bound to the poly[d(AT)].poly[d(AT)]duplex. Proc Natl Acad Sci U S A (1988) 1.16
Sequence specific alkylation of DNA by hairpin pyrrole-imidazole polyamide conjugates. Chem Biol (2000) 1.16
Equilibrium association constants for oligonucleotide-directed triple helix formation at single DNA sites: linkage to cation valence and concentration. Biochemistry (1993) 1.16
Nucleic acid hybridization: triplex stability and energetics. Annu Rev Biophys Biomol Struct (1995) 1.15
The melting behavior of a DNA junction structure: a calorimetric and spectroscopic study. Biopolymers (1987) 1.14
Characterization by 1H NMR of glycosidic conformations in the tetramolecular complex formed by d(GGTTTTTGG). Nucleic Acids Res (1991) 1.14
Towards a minimal motif for artificial transcriptional activators. Chem Biol (2001) 1.12
Fmoc solid phase synthesis of polyamides containing pyrrole and imidazole amino acids. Org Lett (2001) 1.10
Structural and dynamic characterization of the heterodimeric and homodimeric complexes of distamycin and 1-methylimidazole-2-carboxamide-netropsin bound to the minor groove of DNA. Biochemistry (1994) 1.10
Binding of actinomycin D to DNA: evidence for a nonclassical high-affinity binding mode that does not require GpC sites. Proc Natl Acad Sci U S A (1989) 1.10
Effects of the A.T/T.A degeneracy of pyrrole--imidazole polyamide recognition in the minor groove of DNA. Biochemistry (1996) 1.10
Binding affinities of synthetic peptides, pyridine-2-carboxamidonetropsin and 1-methylimidazole-2-carboxamidonetropsin, that form 2:1 complexes in the minor groove of double-helical DNA. Biochemistry (1993) 1.09
Molecular basis for nonadditive mutational effects in Escherichia coli dihydrofolate reductase. Biochemistry (1995) 1.08
Binding site size limit of the 2:1 pyrrole-imidazole polyamide-DNA motif. Proc Natl Acad Sci U S A (1996) 1.08
Influence of base composition, base sequence, and duplex structure on DNA hydration: apparent molar volumes and apparent molar adiabatic compressibilities of synthetic and natural DNA duplexes at 25 degrees C. Biochemistry (1994) 1.08