Published in PLoS One on April 20, 2012
Autophagy in infection, inflammation and immunity. Nat Rev Immunol (2013) 4.16
Autophagy and human diseases. Cell Res (2013) 2.17
Viral and host factors determine innate immune responses in airway epithelial cells from children with wheeze and atopy. Thorax (2014) 1.52
Autophagy and human disease: emerging themes. Curr Opin Genet Dev (2014) 1.47
Immunologic manifestations of autophagy. J Clin Invest (2015) 1.11
IL13 activates autophagy to regulate secretion in airway epithelial cells. Autophagy (2015) 0.93
The clearance of dying cells: table for two. Cell Death Differ (2016) 0.93
Placenta growth factor augments airway hyperresponsiveness via leukotrienes and IL-13. J Clin Invest (2015) 0.90
The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation. Elife (2016) 0.84
Autophagy in airway diseases: a new frontier in human asthma? Allergy (2015) 0.84
Crosstalk between autophagy and inflammatory signalling pathways: balancing defence and homeostasis. Nat Rev Immunol (2016) 0.82
Role of genetic variants of autophagy genes in susceptibility for non-medullary thyroid cancer and patients outcome. PLoS One (2014) 0.81
Impairment of autophagy in the central nervous system during lipopolysaccharide-induced inflammatory stress in mice. Mol Brain (2014) 0.81
Longitudinal follow-up of autophagy and inflammation in brain of APPswePS1dE9 transgenic mice. J Neuroinflammation (2014) 0.80
Epistasis between serine protease inhibitor Kazal-type 5 (SPINK5) and thymic stromal lymphopoietin (TSLP) genes contributes to childhood asthma. J Allergy Clin Immunol (2014) 0.80
Trehalose-mediated autophagy impairs the anti-viral function of human primary airway epithelial cells. PLoS One (2015) 0.79
Reserve autophagic capacity in alveolar epithelia provides a replicative niche for influenza A virus. Am J Respir Cell Mol Biol (2014) 0.78
Proteostasis in pediatric pulmonary pathology. Mol Cell Pediatr (2014) 0.78
The Mucosal Immune System and Its Regulation by Autophagy. Front Immunol (2016) 0.78
Alternaria extract activates autophagy that induces IL-18 release from airway epithelial cells. Biochem Biophys Res Commun (2015) 0.78
Variants in autophagy-related genes and clinical characteristics in melanoma: a population-based study. Cancer Med (2016) 0.77
Lack of autophagy induces steroid-resistant airway inflammation. J Allergy Clin Immunol (2015) 0.77
Association of autophagy related gene polymorphisms with neutrophilic airway inflammation in adult asthma. Korean J Intern Med (2015) 0.77
Increased Autophagy-Related 5 Gene Expression Is Associated with Collagen Expression in the Airways of Refractory Asthmatics. Front Immunol (2017) 0.75
The role of autophagy in allergic inflammation: a new target for severe asthma. Exp Mol Med (2016) 0.75
Investigating regulatory signatures of human autophagy related gene 5 (ATG5) through functional in silico analysis. Meta Gene (2016) 0.75
Autophagy and airway fibrosis: Is there a link? F1000Res (2017) 0.75
Crystallographic Characterization of ATG Proteins and Their Interacting Partners. Methods Enzymol (2016) 0.75
Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet (2006) 115.71
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A (2009) 54.68
Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet (2008) 25.83
Efficiency and power in genetic association studies. Nat Genet (2005) 25.56
METAL: fast and efficient meta-analysis of genomewide association scans. Bioinformatics (2010) 21.21
Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Nat Cell Biol (2006) 9.36
The asthma epidemic. N Engl J Med (2006) 8.60
Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, November 1986. Am Rev Respir Dis (1987) 6.69
FASTSNP: an always up-to-date and extendable service for SNP function analysis and prioritization. Nucleic Acids Res (2006) 5.60
Viral loads and duration of viral shedding in adult patients hospitalized with influenza. J Infect Dis (2009) 5.23
Allergy and allergic diseases. First of two parts. N Engl J Med (2001) 4.33
The Atg5 Atg12 conjugate associates with innate antiviral immune responses. Proc Natl Acad Sci U S A (2007) 3.93
Autophagy protects against Sindbis virus infection of the central nervous system. Cell Host Microbe (2010) 3.79
Genetic and environmental risk factors for intracerebral hemorrhage: preliminary results of a population-based study. Stroke (2002) 3.43
In vivo requirement for Atg5 in antigen presentation by dendritic cells. Immunity (2010) 3.19
A comprehensive evaluation of SNP genotype imputation. Hum Genet (2008) 3.18
Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease. PLoS One (2008) 2.67
The autophagy gene ATG5 plays an essential role in B lymphocyte development. Autophagy (2007) 2.48
Parental history and the risk for childhood asthma. Does mother confer more risk than father? Am J Respir Crit Care Med (1998) 2.20
Altered gene expression profiles in nasal respiratory epithelium reflect stable versus acute childhood asthma. J Allergy Clin Immunol (2005) 2.16
Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema. Proc Natl Acad Sci U S A (2010) 1.82
Segmental bronchoprovocation in allergic rhinitis patients affects mast cell and basophil numbers in nasal and bronchial mucosa. Am J Respir Crit Care Med (2001) 1.72
Deciphering gene-environment interactions through mouse models of allergic asthma. J Allergy Clin Immunol (2008) 1.66
Allergy and allergic diseases. Second of two parts. N Engl J Med (2001) 1.58
Nasal allergen provocation induces adhesion molecule expression and tissue eosinophilia in upper and lower airways. J Allergy Clin Immunol (2001) 1.35
Summary health statistics for U.S. children: National Health Interview Survey, 2008. Vital Health Stat 10 (2009) 1.31
Autophagy protein ATG5 interacts transiently with the hepatitis C virus RNA polymerase (NS5B) early during infection. Virology (2010) 1.31
Recent advances in asthma genetics. Respir Res (2008) 1.23
Eosinophils are a feature of upper and lower airway pathology in non-atopic asthma, irrespective of the presence of rhinitis. Clin Exp Allergy (2000) 1.11
Differences in candidate gene association between European ancestry and African American asthmatic children. PLoS One (2011) 1.09
Autophagy as an emerging dimension to adaptive and innate immunity. Semin Immunol (2009) 0.96
Chromosome 17q21 SNP and severe asthma. J Hum Genet (2010) 0.96
Studies on the allergic and nonallergic nasal inflammation. J Allergy Clin Immunol (1988) 0.95
Deadly triplex: smoke, autophagy and apoptosis. Autophagy (2011) 0.93
Inducible disruption of autophagy in the lung causes airway hyper-responsiveness. Biochem Biophys Res Commun (2010) 0.88
Relevance and implication of genetic determinants to asthma pathophysiology. Curr Opin Allergy Clin Immunol (2011) 0.78
Understanding the inflammatory processes in upper allergic airway disease and asthma. J Allergy Clin Immunol (1998) 0.77
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Toll-like receptor 4 is a sensor for autophagy associated with innate immunity. Immunity (2007) 5.36
Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres. Cell (2006) 4.13
Risk stratification for primary implantation of a cardioverter-defibrillator in patients with ischemic left ventricular dysfunction. J Am Coll Cardiol (2008) 3.73
Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells. Nat Med (2009) 3.17
Lack of effectiveness of hyperbaric oxygen therapy for the treatment of diabetic foot ulcer and the prevention of amputation: a cohort study. Diabetes Care (2013) 3.05
Free radicals, antioxidants in disease and health. Int J Biomed Sci (2008) 2.89
Diesel exhaust particle induction of IL-17A contributes to severe asthma. J Allergy Clin Immunol (2013) 2.62
Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis. EMBO J (2007) 2.61
Altered gene expression profiles in nasal respiratory epithelium reflect stable versus acute childhood asthma. J Allergy Clin Immunol (2005) 2.16
Exposure to traffic-related particles and endotoxin during infancy is associated with wheezing at age 3 years. Am J Respir Crit Care Med (2009) 2.03
Ocular demodicosis as a risk factor of pterygium recurrence. Ophthalmology (2013) 2.00
Importance of cytokines in murine allergic airway disease and human asthma. J Immunol (2010) 1.86
Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling. Blood (2011) 1.86
The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres. EMBO J (2010) 1.83
Variants of thymic stromal lymphopoietin and its receptor associate with eosinophilic esophagitis. J Allergy Clin Immunol (2010) 1.74
Autophagy regulates phagocytosis by modulating the expression of scavenger receptors. Immunity (2013) 1.73
The persistence of atopic dermatitis and filaggrin (FLG) mutations in a US longitudinal cohort. J Allergy Clin Immunol (2012) 1.52
How does amniotic membrane work? Ocul Surf (2004) 1.51
Regulation of IL-4 receptor signaling by STUB1 in lung inflammation. Am J Respir Crit Care Med (2014) 1.50
Toll-like receptor 4 mediates lipopolysaccharide-induced muscle catabolism via coordinate activation of ubiquitin-proteasome and autophagy-lysosome pathways. FASEB J (2010) 1.46
Ubiquitination of inducible nitric oxide synthase is required for its degradation. Proc Natl Acad Sci U S A (2002) 1.45
Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers have no beneficial effect on ablation outcome in chronic persistent atrial fibrillation. Acta Cardiol (2009) 1.42
EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxin-stimulated macrophages. Biochem Pharmacol (2011) 1.41
V75R576 IL-4 receptor alpha is associated with allergic asthma and enhanced IL-4 receptor function. J Immunol (2002) 1.40
Validation of serum markers for blood-brain barrier disruption in traumatic brain injury. J Neurotrauma (2009) 1.34
Chiral drugs: an overview. Int J Biomed Sci (2006) 1.31
Transient aggregation of ubiquitinated proteins is a cytosolic unfolded protein response to inflammation and endoplasmic reticulum stress. J Biol Chem (2012) 1.29
Differences in expression, affinity, and function of soluble (s)IL-4Ralpha and sIL-13Ralpha2 suggest opposite effects on allergic responses. J Immunol (2007) 1.29
Analysis of the life cycle of stat6. Continuous cycling of STAT6 is required for IL-4 signaling. J Biol Chem (2002) 1.28
A hepatic protein, fetuin-A, occupies a protective role in lethal systemic inflammation. PLoS One (2011) 1.25
On the impact of parametric assumptions and robust alternatives for longitudinal data analysis. Biom J (2009) 1.24
A novel method of isolation, preservation, and expansion of human corneal endothelial cells. Invest Ophthalmol Vis Sci (2007) 1.24
Intrinsically defective skin barrier function in children with atopic dermatitis correlates with disease severity. J Allergy Clin Immunol (2008) 1.23
Regulation of inducible nitric oxide synthase by aggresome formation. Proc Natl Acad Sci U S A (2005) 1.23
Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers. Gastroenterology (2006) 1.20
Identification of nitrogen starvation-responsive microRNAs in Arabidopsis thaliana. PLoS One (2012) 1.18
Sex differences in outcome after mild traumatic brain injury. J Neurotrauma (2010) 1.18
Associations between multiple environmental exposures and Glutathione S-Transferase P1 on persistent wheezing in a birth cohort. J Pediatr (2008) 1.16
Human TH17 cells express a functional IL-13 receptor and IL-13 attenuates IL-17A production. J Allergy Clin Immunol (2011) 1.16
Functional effect of the R110Q IL13 genetic variant alone and in combination with IL4RA genetic variants. J Allergy Clin Immunol (2004) 1.16
Calcium-induced abnormal epidermal-like differentiation in cultures of mouse corneal-limbal epithelial cells. Invest Ophthalmol Vis Sci (2004) 1.14
Human amniotic epithelial cells as novel feeder layers for promoting ex vivo expansion of limbal epithelial progenitor cells. Stem Cells (2007) 1.13
Amniotic membrane induces apoptosis of interferon-gamma activated macrophages in vitro. Exp Eye Res (2005) 1.13
A novel mechanism by which interferon-gamma can regulate interleukin (IL)-13 responses. Evidence for intracellular stores of IL-13 receptor alpha -2 and their rapid mobilization by interferon-gamma. J Biol Chem (2002) 1.12
Epithelial EGF receptor signaling mediates airway hyperreactivity and remodeling in a mouse model of chronic asthma. Am J Physiol Lung Cell Mol Physiol (2010) 1.12
Regulation of inducible nitric oxide synthase by rapid cellular turnover and cotranslational down-regulation by dimerization inhibitors. Proc Natl Acad Sci U S A (2004) 1.12
Characterization and comparison of intercellular adherent junctions expressed by human corneal endothelial cells in vivo and in vitro. Invest Ophthalmol Vis Sci (2008) 1.12
A critical role for CHIP in the aggresome pathway. Mol Cell Biol (2008) 1.11
Level of expression of IL-13R alpha 2 impacts receptor distribution and IL-13 signaling. J Immunol (2006) 1.11
Human keratocytes cultured on amniotic membrane stroma preserve morphology and express keratocan. Invest Ophthalmol Vis Sci (2003) 1.11
The -159 C-->T polymorphism of CD14 is associated with nonatopic asthma and food allergy. J Allergy Clin Immunol (2003) 1.10
Identification of KIF3A as a novel candidate gene for childhood asthma using RNA expression and population allelic frequencies differences. PLoS One (2011) 1.10
Differences in candidate gene association between European ancestry and African American asthmatic children. PLoS One (2011) 1.09
Ginsenoside-Rd from panax notoginseng blocks Ca2+ influx through receptor- and store-operated Ca2+ channels in vascular smooth muscle cells. Eur J Pharmacol (2006) 1.09
Intrastromal invasion by limbal epithelial cells is mediated by epithelial-mesenchymal transition activated by air exposure. Am J Pathol (2005) 1.08
Characterization of corneal pannus removed from patients with total limbal stem cell deficiency. Invest Ophthalmol Vis Sci (2004) 1.07
Synthesis, crystallographic and theoretical studies of the new Zintl phases Ba2Cd2Pn3 (Pn = As, Sb), and the solid solutions (Ba(1-x)Sr(x))2Cd2Sb3 and Ba2Cd2(Sb(1-x)As(x))3. Dalton Trans (2009) 1.07
Commonality of functional annotation: a method for prioritization of candidate genes from genome-wide linkage studies. Nucleic Acids Res (2008) 1.07
Development and validation of a 6-day standard for the identification of frequent mental distress. Soc Psychiatry Psychiatr Epidemiol (2010) 1.07
Allergy-driven alternative splicing of IL-13 receptor alpha2 yields distinct membrane and soluble forms. J Immunol (2006) 1.07
Comparison of measures of marker informativeness for ancestry and admixture mapping. BMC Genomics (2011) 1.07
Diisocyanate asthma and gene-environment interactions with IL4RA, CD-14, and IL-13 genes. Ann Allergy Asthma Immunol (2006) 1.06
Epicutaneous aeroallergen exposure induces systemic TH2 immunity that predisposes to allergic nasal responses. J Allergy Clin Immunol (2006) 1.06
The fate of limbal epithelial progenitor cells during explant culture on intact amniotic membrane. Invest Ophthalmol Vis Sci (2007) 1.05
Preservation and expansion of the primate keratocyte phenotype by downregulating TGF-beta signaling in a low-calcium, serum-free medium. Invest Ophthalmol Vis Sci (2006) 1.04
Deficiency in ClC-3 chloride channels prevents rat aortic smooth muscle cell proliferation. Circ Res (2002) 1.04
Activation of the caspase-8/Bid and Bax pathways in aspirin-induced apoptosis in gastric cancer. Carcinogenesis (2004) 1.04
Regulation of intracellular Cl- concentration through volume-regulated ClC-3 chloride channels in A10 vascular smooth muscle cells. J Biol Chem (2004) 1.02
Population structure analysis using rare and common functional variants. BMC Proc (2011) 1.02
Mold exposure during infancy as a predictor of potential asthma development. Ann Allergy Asthma Immunol (2009) 1.02
Aeroallergen sensitization in healthy children: racial and socioeconomic correlates. J Pediatr (2007) 1.01
Serum macrophage migration-inhibitory factor as a diagnostic and prognostic biomarker for gastric cancer. Cancer (2009) 1.01
Autophagy and autoimmunity crosstalks. Front Immunol (2013) 1.01
The fanconi anemia pathway limits human papillomavirus replication. J Virol (2012) 1.01
Traffic-related air pollution exposure in the first year of life and behavioral scores at 7 years of age. Environ Health Perspect (2013) 1.00
Intracellular formation of "undisruptable" dimers of inducible nitric oxide synthase. Proc Natl Acad Sci U S A (2003) 1.00