Published in J Biol Chem on January 10, 2002
Fibrotic disease and the T(H)1/T(H)2 paradigm. Nat Rev Immunol (2004) 6.75
Regulation and function of the interleukin 13 receptor alpha 2 during a T helper cell type 2-dominant immune response. J Exp Med (2003) 2.71
Th2 Cytokines and Atopic Dermatitis. J Clin Cell Immunol (2011) 1.91
Molecular basis for shared cytokine recognition revealed in the structure of an unusually high affinity complex between IL-13 and IL-13Ralpha2. Structure (2010) 1.79
Cytokine receptor-mediated trafficking of preformed IL-4 in eosinophils identifies an innate immune mechanism of cytokine secretion. Proc Natl Acad Sci U S A (2006) 1.54
Lysophosphatidic acid signaling in airway epithelium: role in airway inflammation and remodeling. Cell Signal (2008) 1.28
Human pulmonary fibroblasts exhibit altered interleukin-4 and interleukin-13 receptor subunit expression in idiopathic interstitial pneumonia. Am J Pathol (2004) 1.20
Impact of interleukin-13 responsiveness on the synthetic and proliferative properties of Th1- and Th2-type pulmonary granuloma fibroblasts. Am J Pathol (2003) 1.15
Lysophosphatidic acid induces interleukin-13 (IL-13) receptor alpha2 expression and inhibits IL-13 signaling in primary human bronchial epithelial cells. J Biol Chem (2007) 1.00
A novel and sensitive ELISA reveals that the soluble form of IL-13R-alpha2 is not expressed in plasma of healthy or asthmatic subjects. Clin Exp Allergy (2008) 0.99
Chitosan IFN-gamma-pDNA Nanoparticle (CIN) Therapy for Allergic Asthma. Genet Vaccines Ther (2003) 0.99
IL-13Rα2 has a protective role in a mouse model of cutaneous inflammation. J Immunol (2010) 0.92
Matrix metalloproteinase 8 contributes to solubilization of IL-13 receptor alpha2 in vivo. J Allergy Clin Immunol (2008) 0.88
IFN-gamma, IL-4 and IL-13 modulate responsiveness of human airway smooth muscle cells to IL-13. Respir Res (2008) 0.87
Chitosan Interferon-gamma Nanogene Therapy for Lung Disease: Modulation of T-Cell and Dendritic Cell Immune Responses. Allergy Asthma Clin Immunol (2008) 0.80
Chitinase 3-like-1 and its receptors in Hermansky-Pudlak syndrome-associated lung disease. J Clin Invest (2015) 0.80
Commentary: IL-4 and IL-13 receptors and signaling. Cytokine (2015) 0.77
Cytokine induction of VCAM-1 but not IL13Rα2 on glioma cells: a tale of two antibodies. PLoS One (2014) 0.75
IL-17A enhances IL-13 activity by enhancing IL-13-induced signal transducer and activator of transcription 6 activation. J Allergy Clin Immunol (2016) 0.75
Altered gene expression profiles in nasal respiratory epithelium reflect stable versus acute childhood asthma. J Allergy Clin Immunol (2005) 2.16
Exposure to traffic-related particles and endotoxin during infancy is associated with wheezing at age 3 years. Am J Respir Crit Care Med (2009) 2.03
Importance of cytokines in murine allergic airway disease and human asthma. J Immunol (2010) 1.86
V75R576 IL-4 receptor alpha is associated with allergic asthma and enhanced IL-4 receptor function. J Immunol (2002) 1.40
Differences in expression, affinity, and function of soluble (s)IL-4Ralpha and sIL-13Ralpha2 suggest opposite effects on allergic responses. J Immunol (2007) 1.29
Analysis of the life cycle of stat6. Continuous cycling of STAT6 is required for IL-4 signaling. J Biol Chem (2002) 1.28
Human TH17 cells express a functional IL-13 receptor and IL-13 attenuates IL-17A production. J Allergy Clin Immunol (2011) 1.16
Epithelial EGF receptor signaling mediates airway hyperreactivity and remodeling in a mouse model of chronic asthma. Am J Physiol Lung Cell Mol Physiol (2010) 1.12
Functional variant in the autophagy-related 5 gene promotor is associated with childhood asthma. PLoS One (2012) 1.12
Level of expression of IL-13R alpha 2 impacts receptor distribution and IL-13 signaling. J Immunol (2006) 1.11
The -159 C-->T polymorphism of CD14 is associated with nonatopic asthma and food allergy. J Allergy Clin Immunol (2003) 1.10
Identification of KIF3A as a novel candidate gene for childhood asthma using RNA expression and population allelic frequencies differences. PLoS One (2011) 1.10
Allergy-driven alternative splicing of IL-13 receptor alpha2 yields distinct membrane and soluble forms. J Immunol (2006) 1.07
Diisocyanate asthma and gene-environment interactions with IL4RA, CD-14, and IL-13 genes. Ann Allergy Asthma Immunol (2006) 1.06
Epicutaneous aeroallergen exposure induces systemic TH2 immunity that predisposes to allergic nasal responses. J Allergy Clin Immunol (2006) 1.06
Mold exposure during infancy as a predictor of potential asthma development. Ann Allergy Asthma Immunol (2009) 1.02
Traffic-related air pollution exposure in the first year of life and behavioral scores at 7 years of age. Environ Health Perspect (2013) 1.00
Downregulation of glutathione S-transferase pi in asthma contributes to enhanced oxidative stress. J Allergy Clin Immunol (2011) 0.94
Methylation of STAT6 modulates STAT6 phosphorylation, nuclear translocation, and DNA-binding activity. J Immunol (2004) 0.92
IL-13R alpha 2 membrane and soluble isoforms differ in humans and mice. J Immunol (2009) 0.92
Allergen-dependent solubilization of IL-13 receptor alpha2 reveals a novel mechanism to regulate allergy. J Allergy Clin Immunol (2006) 0.91
Placenta growth factor augments airway hyperresponsiveness via leukotrienes and IL-13. J Clin Invest (2015) 0.90
Matrix metalloproteinase 8 contributes to solubilization of IL-13 receptor alpha2 in vivo. J Allergy Clin Immunol (2008) 0.88
Dectin-1 and IL-17A suppress murine asthma induced by Aspergillus versicolor but not Cladosporium cladosporioides due to differences in β-glucan surface exposure. J Immunol (2012) 0.87
Differential effects of rapamycin and dexamethasone in mouse models of established allergic asthma. PLoS One (2013) 0.84
Asthma genetics: personalizing medicine. J Asthma (2008) 0.83
Rank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations. Hum Genomics (2013) 0.80
AncestrySNPminer: a bioinformatics tool to retrieve and develop ancestry informative SNP panels. Genomics (2012) 0.79
DNA binding activity of cytoplasmic phosphorylated Stat6 is masked by an interaction with a detergent-sensitive factor. J Biol Chem (2003) 0.77
Genetic biomarkers of health-related quality of life in pediatric asthma. J Pediatr (2011) 0.75
Air pollution and allergic diseases. Curr Opin Pediatr (2015) 0.75
Successful administration of cytarabine in a 16-month-old girl with acute myelogenous leukemia and cytarabine syndrome. Ann Allergy Asthma Immunol (2009) 0.75