Published in Clin Exp Med on April 29, 2012
Genomic profile analysis of diffuse-type gastric cancers. Genome Biol (2014) 1.07
Novel CDH1 germline mutations identified in Chinese gastric cancer patients. World J Gastroenterol (2013) 0.88
Quantification of mutant E-cadherin using bioimaging analysis of in situ fluorescence microscopy. A new approach to CDH1 missense variants. Eur J Hum Genet (2014) 0.81
Identification and characterization of CDH1 germline variants in sporadic gastric cancer patients and in individuals at risk of gastric cancer. PLoS One (2013) 0.81
Diagnostic and prognostic significance of glypican 5 and glypican 6 gene expression levels in gastric adenocarcinoma. Mol Clin Oncol (2015) 0.75
CDH1 mutations in gastric cancer patients from northern Brazil identified by Next- Generation Sequencing (NGS). Genet Mol Biol (2016) 0.75
THE TWO HISTOLOGICAL MAIN TYPES OF GASTRIC CARCINOMA: DIFFUSE AND SO-CALLED INTESTINAL-TYPE CARCINOMA. AN ATTEMPT AT A HISTO-CLINICAL CLASSIFICATION. Acta Pathol Microbiol Scand (1965) 22.65
A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature (1998) 8.48
E-cadherin germline mutations in familial gastric cancer. Nature (1998) 6.72
The cell-cell adhesion molecule E-cadherin. Cell Mol Life Sci (2008) 3.77
Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer. JAMA (2007) 3.62
Genetic defects in the human glycome. Nat Rev Genet (2006) 3.59
Hereditary diffuse gastric cancer: updated consensus guidelines for clinical management and directions for future research. J Med Genet (2010) 3.15
Germline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteria. J Med Genet (2004) 2.95
Mutations of the human E-cadherin (CDH1) gene. Hum Mutat (1998) 2.84
Abnormal immunoreactivity of the E-cadherin-catenin complex in gastric carcinoma: relationship with patient survival. Gastroenterology (1997) 1.86
E-cadherin/β-catenin complex and the epithelial barrier. J Biomed Biotechnol (2011) 1.61
Identification of CDH1 germline missense mutations associated with functional inactivation of the E-cadherin protein in young gastric cancer probands. Hum Mol Genet (2003) 1.42
Germline mutations of the E-cadherin(CDH1) and TP53 genes, rather than of RUNX3 and HPP1, contribute to genetic predisposition in German gastric cancer patients. J Med Genet (2004) 1.38
The crystal structure of human E-cadherin domains 1 and 2, and comparison with other cadherins in the context of adhesion mechanism. J Mol Biol (2007) 1.32
Site-directed mutagenesis of large (13-kb) plasmids in a single-PCR procedure. Biotechniques (2000) 1.10
Modulation of E-cadherin function and dysfunction by N-glycosylation. Cell Mol Life Sci (2010) 1.10
E-cadherin germline missense mutations and cell phenotype: evidence for the independence of cell invasion on the motile capabilities of the cells. Hum Mol Genet (2003) 1.02
E-cadherin mutations and cell motility: a genotype-phenotype correlation. Exp Cell Res (2009) 1.02
Reduction in membranous expression of beta-catenin and increased cytoplasmic E-cadherin expression predict poor survival in gastric cancer. Br J Cancer (1999) 1.00
E-cadherin and hereditary diffuse gastric cancer. Surgery (2007) 0.99
Identification of seven novel germline mutations in the human E-cadherin (CDH1) gene. Hum Mutat (2007) 0.98
E-cadherin genetic screening and clinico-pathologic characteristics of early onset gastric cancer. Eur J Cancer (2010) 0.97
A model to infer the pathogenic significance of CDH1 germline missense variants. J Mol Med (Berl) (2006) 0.92
E-cadherin immunoexpression patterns in the characterisation of gastric carcinoma histotypes. J Clin Pathol (2010) 0.82
CDH1 germline mutation in hereditary gastric carcinoma. World J Gastroenterol (2004) 0.80
Helicobacter pylori and interleukin 1 genotyping: an opportunity to identify high-risk individuals for gastric carcinoma. J Natl Cancer Inst (2002) 4.43
Evidence for an association between Chlamydia psittaci and ocular adnexal lymphomas. J Natl Cancer Inst (2004) 4.07
BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC. Oncogene (2003) 3.34
Evaluation of tumor microsatellite instability using five quasimonomorphic mononucleotide repeats and pentaplex PCR. Gastroenterology (2002) 2.85
The prevalence of PIK3CA mutations in gastric and colon cancer. Eur J Cancer (2005) 2.83
p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion. Cancer Cell (2005) 2.65
[18F]fluorocholine PET/CT imaging for the detection of recurrent prostate cancer at PSA relapse: experience in 100 consecutive patients. Eur J Nucl Med Mol Imaging (2006) 2.63
BRAF mutations characterize colon but not gastric cancer with mismatch repair deficiency. Oncogene (2003) 2.56
Local excision after preoperative chemoradiotherapy for rectal cancer: results of a multicenter phase II clinical trial. Dis Colon Rectum (2013) 2.52
Predictive role of the UGT1A1, UGT1A7, and UGT1A9 genetic variants and their haplotypes on the outcome of metastatic colorectal cancer patients treated with fluorouracil, leucovorin, and irinotecan. J Clin Oncol (2009) 2.40
A proinflammatory genetic profile increases the risk for chronic atrophic gastritis and gastric carcinoma. Gastroenterology (2003) 2.39
Duffy negative antigen is no longer a barrier to Plasmodium vivax--molecular evidences from the African West Coast (Angola and Equatorial Guinea). PLoS Negl Trop Dis (2011) 2.15
Somatic mutations and deletions of the E-cadherin gene predict poor survival of patients with gastric cancer. J Clin Oncol (2013) 1.89
Capsule endoscopy is useful and safe for small-bowel surveillance in familial adenomatous polyposis. Gastrointest Endosc (2008) 1.69
Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status. Hum Mol Genet (2004) 1.66
Epithelial E- and P-cadherins: role and clinical significance in cancer. Biochim Biophys Acta (2012) 1.64
Stathmin activity influences sarcoma cell shape, motility, and metastatic potential. Mol Biol Cell (2008) 1.62
BRAF-V600E is not involved in the colorectal tumorigenesis of HNPCC in patients with functional MLH1 and MSH2 genes. Oncogene (2005) 1.62
Structural basis for mammalian vitamin B12 transport by transcobalamin. Proc Natl Acad Sci U S A (2006) 1.59
Model of the early development of diffuse gastric cancer in E-cadherin mutation carriers and its implications for patient screening. J Pathol (2004) 1.59
Monoclonal antibody treatment of mixed cryoglobulinemia resistant to interferon alpha with an anti-CD20. Blood (2002) 1.58
Clinical presentation and outcome of colorectal cancer in HIV-positive patients: a clinical case-control study. Onkologie (2009) 1.58
HCV-associated B cell clonalities in the liver do not carry the t(14;18) chromosomal translocation. Hepatology (2005) 1.57
Carboxylesterase isoform 2 mRNA expression in peripheral blood mononuclear cells is a predictive marker of the irinotecan to SN38 activation step in colorectal cancer patients. Clin Cancer Res (2005) 1.47
Characterization of a recurrent germ line mutation of the E-cadherin gene: implications for genetic testing and clinical management. Clin Cancer Res (2005) 1.46
A microRNA signature defines chemoresistance in ovarian cancer through modulation of angiogenesis. Proc Natl Acad Sci U S A (2013) 1.44
Screening E-cadherin in gastric cancer families reveals germline mutations only in hereditary diffuse gastric cancer kindred. Hum Mutat (2002) 1.44
The tumor suppressor functions of p27(kip1) include control of the mesenchymal/amoeboid transition. Mol Cell Biol (2009) 1.43
Identification of CDH1 germline missense mutations associated with functional inactivation of the E-cadherin protein in young gastric cancer probands. Hum Mol Genet (2003) 1.42
Germline CDH1 deletions in hereditary diffuse gastric cancer families. Hum Mol Genet (2009) 1.39
Feasibility and diagnostic agreement in teledermatopathology using a virtual slide system. Hum Pathol (2007) 1.39
Pegylated interferon-alpha, ribavirin, and rituximab combined therapy of hepatitis C virus-related mixed cryoglobulinemia: a long-term study. Blood (2010) 1.37
Targeted intraoperative radiotherapy impairs the stimulation of breast cancer cell proliferation and invasion caused by surgical wounding. Clin Cancer Res (2008) 1.34
Highlights of the EORTC St. Gallen International Expert Consensus on the primary therapy of gastric, gastroesophageal and oesophageal cancer - differential treatment strategies for subtypes of early gastroesophageal cancer. Eur J Cancer (2012) 1.32
Vitamin B12: unique metalorganic compounds and the most complex vitamins. Molecules (2010) 1.32
{alpha}-Catenin mediates initial E-cadherin-dependent cell-cell recognition and subsequent bond strengthening. Proc Natl Acad Sci U S A (2008) 1.31
Lack of microRNA-101 causes E-cadherin functional deregulation through EZH2 up-regulation in intestinal gastric cancer. J Pathol (2012) 1.30
BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: primary or secondary genetic events in colorectal carcinogenesis? BMC Cancer (2008) 1.30
Genetics, pathology, and clinics of familial gastric cancer. Int J Surg Pathol (2006) 1.29
Genome-wide DNA profiling of marginal zone lymphomas identifies subtype-specific lesions with an impact on the clinical outcome. Blood (2010) 1.27
Stereotyped B-cell receptor is an independent risk factor of chronic lymphocytic leukemia transformation to Richter syndrome. Clin Cancer Res (2009) 1.22
Quantification of epigenetic and genetic 2nd hits in CDH1 during hereditary diffuse gastric cancer syndrome progression. Gastroenterology (2009) 1.21
Food groups and risk of non-Hodgkin lymphoma: a multicenter, case-control study in Italy. Int J Cancer (2006) 1.21
Activated BRAF targets proximal colon tumors with mismatch repair deficiency and MLH1 inactivation. Genes Chromosomes Cancer (2004) 1.18
Antibody production and in vitro behavior of CD27-defined B-cell subsets: persistent hepatitis C virus infection changes the rules. J Virol (2006) 1.18
E-Cadherin (CDH1) and p53 rather than SMAD4 and Caspase-10 germline mutations contribute to genetic predisposition in Portuguese gastric cancer patients. Eur J Cancer (2004) 1.17
p27Kip1 expression inhibits glioblastoma growth, invasion, and tumor-induced neoangiogenesis. Mol Cancer Ther (2008) 1.16
Biomarkers for gastric cancer: prognostic, predictive or targets of therapy? Virchows Arch (2014) 1.15
Helicobacter pylori infection induces genetic instability of nuclear and mitochondrial DNA in gastric cells. Clin Cancer Res (2009) 1.14
Oncogenic mutations in gastric cancer with microsatellite instability. Eur J Cancer (2011) 1.14
Helicobacter pylori infection generates genetic instability in gastric cells. Biochim Biophys Acta (2010) 1.14
Allele-specific CDH1 downregulation and hereditary diffuse gastric cancer. Hum Mol Genet (2009) 1.13
Successful vaccination induces multifunctional memory T-cell precursors associated with early control of hepatitis C virus. Gastroenterology (2012) 1.12
Hereditary gastric cancer. Best Pract Res Clin Gastroenterol (2009) 1.12
Consensus guidelines on severe acute pancreatitis. Dig Liver Dis (2015) 1.12
CagA associates with c-Met, E-cadherin, and p120-catenin in a multiproteic complex that suppresses Helicobacter pylori-induced cell-invasive phenotype. J Infect Dis (2009) 1.10
De novo expression of CD44 variants in sporadic and hereditary gastric cancer. Lab Invest (2010) 1.10
Modulation of E-cadherin function and dysfunction by N-glycosylation. Cell Mol Life Sci (2010) 1.10
The role of N-acetylglucosaminyltransferase III and V in the post-transcriptional modifications of E-cadherin. Hum Mol Genet (2009) 1.09
Breast metastasis of primary colon cancer with micrometastasis in the axillary sentinel node: a metastasis that metastasized? Diagn Pathol (2011) 1.09
Candidate driver genes in microsatellite-unstable colorectal cancer. Int J Cancer (2011) 1.08
B-Raf(V600E) cooperates with alternative spliced Rac1b to sustain colorectal cancer cell survival. Gastroenterology (2008) 1.08
Long-term outcome of patients with complete pathologic response after neoadjuvant chemoradiation for cT3 rectal cancer: implications for local excision surgical strategies. Ann Surg Oncol (2011) 1.08
Specific clinical and biological features characterize inflammatory bowel disease associated colorectal cancers showing microsatellite instability. J Clin Oncol (2007) 1.08
The intracellular E-cadherin germline mutation V832 M lacks the ability to mediate cell-cell adhesion and to suppress invasion. Oncogene (2003) 1.08
Clinical and dermoscopic features of porokeratosis of Mibelli. Arch Dermatol (2009) 1.08
Genetic characterization of p27(kip1) and stathmin in controlling cell proliferation in vivo. Cell Cycle (2014) 1.07
Epidermal growth factor receptor structural alterations in gastric cancer. BMC Cancer (2008) 1.07
Concomitant RASSF1A hypermethylation and KRAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer. Oncogene (2005) 1.07
Risk factors for ovarian cancer histotypes. Eur J Cancer (2007) 1.06
Helicobacter pylori induces gastric epithelial cell invasion in a c-Met and type IV secretion system-dependent manner. J Biol Chem (2006) 1.05
Loss of heterozygosity and promoter methylation, but not mutation, may underlie loss of TFF1 in gastric carcinoma. Lab Invest (2002) 1.05
Extrasalivary lymphoma development in Sjögren's syndrome: clonal evolution from parotid gland lymphoproliferation and role of local triggering. Arthritis Rheum (2003) 1.05
C677T and A1298C MTHFR polymorphisms, a challenge for antifolate and fluoropyrimidine-based therapy personalisation. Eur J Cancer (2009) 1.04
Sliding helix and change of coordination geometry in a model di-MnII protein. Angew Chem Int Ed Engl (2003) 1.04
Identification of novel chimpanzee MHC class I and II alleles using an improved sequence-based typing strategy. Hum Immunol (2006) 1.04
Luteolin, quercetin and ursolic acid are potent inhibitors of proliferation and inducers of apoptosis in both KRAS and BRAF mutated human colorectal cancer cells. Cancer Lett (2009) 1.02
Intrahepatic B cell clonal expansions and extrahepatic manifestations of chronic HCV infection. Eur J Immunol (2004) 1.02
CPEB1, a novel gene silenced in gastric cancer: a Drosophila approach. Gut (2011) 1.02
E-cadherin germline missense mutations and cell phenotype: evidence for the independence of cell invasion on the motile capabilities of the cells. Hum Mol Genet (2003) 1.02
E-cadherin mutations and cell motility: a genotype-phenotype correlation. Exp Cell Res (2009) 1.02
Renal cell cancer and body size at different ages: an Italian multicenter case-control study. Am J Epidemiol (2007) 1.01
Structural study on ligand specificity of human vitamin B12 transporters. Biochem J (2007) 1.01
E-cadherin and adherens-junctions stability in gastric carcinoma: functional implications of glycosyltransferases involving N-glycan branching biosynthesis, N-acetylglucosaminyltransferases III and V. Biochim Biophys Acta (2013) 1.01
Analysis and design of turns in alpha-helical hairpins. J Mol Biol (2005) 1.00
Reproductive, menstrual, and other hormone-related factors and risk of renal cell cancer. Int J Cancer (2008) 1.00
P-cadherin is coexpressed with CD44 and CD49f and mediates stem cell properties in basal-like breast cancer. Stem Cells (2012) 0.99
Interobserver agreement in describing video capsule endoscopy findings: a multicentre prospective study. Dig Liver Dis (2011) 0.99
CDH1-related hereditary diffuse gastric cancer syndrome: clinical variations and implications for counseling. Int J Cancer (2011) 0.98