|
1
|
Synthesis, molecular docking and evaluation of thiazolyl-pyrazoline derivatives as EGFR TK inhibitors and potential anticancer agents.
|
Bioorg Med Chem Lett
|
2011
|
1.14
|
|
2
|
Hydroxylation activity of P450 BM-3 mutant F87V towards aromatic compounds and its application to the synthesis of hydroquinone derivatives from phenolic compounds.
|
Appl Microbiol Biotechnol
|
2004
|
0.94
|
|
3
|
Protection of SH-SY5Y neuronal cells from glutamate-induced apoptosis by 3,6'-disinapoyl sucrose, a bioactive compound isolated from Radix Polygala.
|
J Biomed Biotechnol
|
2011
|
0.91
|
|
4
|
Isoflurane preconditioning confers cardioprotection by activation of ALDH2.
|
PLoS One
|
2013
|
0.90
|
|
5
|
Extended calix[4]arene analogues by two P-CuI-P bridges and anion encapsulation.
|
Inorg Chem
|
2006
|
0.90
|
|
6
|
Design, synthesis, biological evaluation and molecular modeling of 1,3,4-oxadiazoline analogs of combretastatin-A4 as novel antitubulin agents.
|
Bioorg Med Chem
|
2011
|
0.89
|
|
7
|
14-day repeat-dose oral toxicity evaluation of oxazyme in rats and dogs.
|
Int J Toxicol
|
2009
|
0.84
|
|
8
|
The antiviral drug ribavirin is a selective inhibitor of S-adenosyl-L-homocysteine hydrolase from Trypanosoma cruzi.
|
Bioorg Med Chem
|
2007
|
0.84
|
|
9
|
Melatonin protects against amyloid-β-induced impairments of hippocampal LTP and spatial learning in rats.
|
Synapse
|
2013
|
0.82
|
|
10
|
Protective effects of farrerol against hydrogen-peroxide-induced apoptosis in human endothelium-derived EA.hy926 cells.
|
Can J Physiol Pharmacol
|
2013
|
0.81
|
|
11
|
Synthesis of C(7) modified chrysin derivatives designing to inhibit beta-ketoacyl-acyl carrier protein synthase III (FabH) as antibiotics.
|
Bioorg Med Chem
|
2009
|
0.81
|
|
12
|
Molecular docking, kinetics study, and structure-activity relationship analysis of quercetin and its analogous as Helicobacter pylori urease inhibitors.
|
J Agric Food Chem
|
2012
|
0.81
|
|
13
|
Synthesis and biological activity of 4-substituted benzoxazolone derivatives as a new class of sEH inhibitors with high anti-inflammatory activity in vivo.
|
Bioorg Med Chem Lett
|
2013
|
0.81
|
|
14
|
Val⁸-GLP-1 remodels synaptic activity and intracellular calcium homeostasis impaired by amyloid β peptide in rats.
|
J Neurosci Res
|
2013
|
0.80
|
|
15
|
Screening and industrial application of unique microbial reactions involved in nucleic acid and lipid metabolisms.
|
Biosci Biotechnol Biochem
|
2006
|
0.79
|
|
16
|
Hypolipidemic activity in Sprague-Dawley rats and constituents of a novel natural vegetable oil from Cornus wilsoniana fruits.
|
J Food Sci
|
2012
|
0.79
|
|
17
|
Treatment of simulated wastewater containing Reactive Red 195 by zero-valent iron/activated carbon combined with microwave discharge electrodeless lamp/sodium hypochlorite.
|
J Environ Sci (China)
|
2010
|
0.79
|
|
18
|
Synthesis, biological evaluation and 3D-QSAR studies of novel 4,5-dihydro-1H-pyrazole niacinamide derivatives as BRAF inhibitors.
|
Bioorg Med Chem
|
2012
|
0.78
|
|
19
|
Oxidative stress in di-n-butyl-di-(4-chlorobenzohydroxamato)tin (IV)-induced hepatotoxicity determined by proteomic profiles.
|
Toxicol Lett
|
2012
|
0.78
|
|
20
|
Design, modification and 3D QSAR studies of novel 2,3-dihydrobenzo[b][1,4]dioxin-containing 4,5-dihydro-1H-pyrazole derivatives as inhibitors of B-Raf kinase.
|
Bioorg Med Chem
|
2012
|
0.78
|
|
21
|
Synthesis, biological evaluation, and molecular docking studies of N-((1,3-diphenyl-1H-pyrazol-4-yl)methyl)aniline derivatives as novel anticancer agents.
|
Bioorg Med Chem
|
2012
|
0.78
|
|
22
|
Design, synthesis and biological evaluation of chrysin long-chain derivatives as potential anticancer agents.
|
Bioorg Med Chem
|
2009
|
0.78
|
|
23
|
The rationale for targeting the NAD/NADH cofactor binding site of parasitic S-adenosyl-L-homocysteine hydrolase for the design of anti-parasitic drugs.
|
Nucleosides Nucleotides Nucleic Acids
|
2009
|
0.77
|
|
24
|
Metalloprotein Inhibitors for the Treatment of Human Diseases.
|
Curr Top Med Chem
|
2016
|
0.77
|
|
25
|
Antiviral therapy delays esophageal variceal bleeding in hepatitis B virus-related cirrhosis.
|
World J Gastroenterol
|
2013
|
0.77
|
|
26
|
Suppression of gastric cancer growth by adenovirus-mediated transfer of the PTEN gene.
|
World J Gastroenterol
|
2005
|
0.77
|
|
27
|
Apoptosis induced neurotoxicity of Di-n-butyl-di-(4-chlorobenzohydroxamato) Tin (IV) via mitochondria-mediated pathway in PC12 cells.
|
Toxicol In Vitro
|
2012
|
0.77
|
|
28
|
Polycyclic aromatic hydrocarbons in surface sediments of the Jialu River.
|
Ecotoxicology
|
2011
|
0.77
|
|
29
|
The neuroprotection of Rattin against amyloid β peptide in spatial memory and synaptic plasticity of rats.
|
Hippocampus
|
2013
|
0.76
|
|
30
|
Comparative kinetics of cofactor association and dissociation for the human and trypanosomal S-adenosylhomocysteine hydrolases. 3. Role of lysyl and tyrosyl residues of the C-terminal extension.
|
Biochemistry
|
2010
|
0.76
|
|
31
|
Metabolism of polychlorinated dibenzo-p-dioxins by cytochrome P450 BM-3 and its mutant.
|
Biotechnol Lett
|
2004
|
0.76
|
|
32
|
Two extracellular proteins with alkaline peroxidase activity, a novel cytochrome c and a catalase-peroxidase, from Bacillus sp. No.13.
|
Biochim Biophys Acta
|
2004
|
0.76
|
|
33
|
2',10'-Dibromo-spiro-[cylohexane-1,6-di-benzo[d,f][1,3]dioxepine].
|
Acta Crystallogr Sect E Struct Rep Online
|
2010
|
0.75
|
|
34
|
Fraxinellone.
|
Acta Crystallogr Sect E Struct Rep Online
|
2011
|
0.75
|
|
35
|
Novel NGF-potentiating limonoids from the fruits of Melia toosendan.
|
Fitoterapia
|
2013
|
0.75
|
|
36
|
Tetra-aqua-bis[1,1'-(4-methoxy-naph-thalene-1,3-diyldimethyl-ene)pyridinium-3-carboxyl-ate-κO]cobalt(II) bis-(perchlorate) hexa-hydrate.
|
Acta Crystallogr Sect E Struct Rep Online
|
2008
|
0.75
|
|
37
|
(1S*,2R*,4aS*,6aS*,6bR*,10S*,12aR*,14aS*)-10-Hydr-oxy-1,2,6a,6b,9,9,12a-hepta-methyl-perhydro-picene-4a,14a-carbolactone.
|
Acta Crystallogr Sect E Struct Rep Online
|
2009
|
0.75
|
|
38
|
[A new model of skin avulsion injuries in rats].
|
Zhonghua Zheng Xing Wai Ke Za Zhi
|
2008
|
0.75
|
|
39
|
Design, synthesis and biological evaluation of urea derivatives from o-hydroxybenzylamines and phenylisocyanate as potential FabH inhibitors.
|
Bioorg Med Chem
|
2011
|
0.75
|
|
40
|
[The comparison of fludarabine or antithymocyte globulin based non-myeloablative conditioning regimen for haematologic diseases with graft-versus-host disease].
|
Zhonghua Xue Ye Xue Za Zhi
|
2011
|
0.75
|
|
41
|
Pharmacokinetics and tissue distribution of furanodiene W/O/W multiple emulsions in rats by a fast and sensitive HPLC-APCI-MS/MS method.
|
Xenobiotica
|
2013
|
0.75
|
|
42
|
[Limonoids from fruits of Melia toosendan].
|
Yao Xue Xue Bao
|
2010
|
0.75
|
|
43
|
Synthesis, biological evaluation and molecular docking studies of flavone and isoflavone derivatives as a novel class of KSP (kinesin spindle protein) inhibitors.
|
Eur J Med Chem
|
2013
|
0.75
|
|
44
|
A new ionic liquid-water-organic solvent three phase microextraction for simultaneous preconcentration flavonoids and anthraquinones from traditional Chinese prescription.
|
J Pharm Biomed Anal
|
2013
|
0.75
|
|
45
|
Design, synthesis and biological evaluation of pyridine acyl sulfonamide derivatives as novel COX-2 inhibitors.
|
Bioorg Med Chem
|
2011
|
0.75
|
|
46
|
Synthesis, biological evaluation and molecular docking of novel 5-phenyl-1H-pyrazol derivatives as potential BRAF(V600E) inhibitors.
|
Org Biomol Chem
|
2013
|
0.75
|
|
47
|
Discovery of novel dinitrobenzotrifluoride containing o-hydroxybenzylamine derivatives as potential antibacterial agents.
|
Med Chem
|
2015
|
0.75
|
|
48
|
[Separation and purification process of total flavones and total tannins from Apocynum venetum leaves with macroreticular resin].
|
Zhongguo Zhong Yao Za Zhi
|
2008
|
0.75
|