Published in PLoS Pathog on May 10, 2012
Sensing of bacterial type IV secretion via the unfolded protein response. MBio (2013) 1.09
The study of the core part and non-repeating elements of the O-antigen of Brucella lipopolysaccharide. Carbohydr Res (2012) 0.94
Brucella β 1,2 cyclic glucan is an activator of human and mouse dendritic cells. PLoS Pathog (2012) 0.92
Brucella abortus depends on pyruvate phosphate dikinase and malic enzyme but not on Fbp and GlpX fructose-1,6-bisphosphatases for full virulence in laboratory models. J Bacteriol (2014) 0.91
Functional Genomic Screen Identifies Klebsiella pneumoniae Factors Implicated in Blocking Nuclear Factor κB (NF-κB) Signaling. J Biol Chem (2015) 0.89
Comparative genomics of early-diverging Brucella strains reveals a novel lipopolysaccharide biosynthesis pathway. MBio (2012) 0.88
Brucella discriminates between mouse dendritic cell subsets upon in vitro infection. Virulence (2015) 0.87
Neutrophils exert a suppressive effect on Th1 responses to intracellular pathogen Brucella abortus. PLoS Pathog (2013) 0.86
Mutants in the lipopolysaccharide of Brucella ovis are attenuated and protect against B. ovis infection in mice. Vet Res (2014) 0.86
Brucella melitensis MucR, an orthologue of Sinorhizobium meliloti MucR, is involved in resistance to oxidative, detergent, and saline stresses and cell envelope modifications. J Bacteriol (2012) 0.84
Brucella abortus Induces the Premature Death of Human Neutrophils through the Action of Its Lipopolysaccharide. PLoS Pathog (2015) 0.83
Bartonella and Brucella--weapons and strategies for stealth attack. Cold Spring Harb Perspect Med (2013) 0.83
Peptide nucleic acids inhibit growth of Brucella suis in pure culture and in infected murine macrophages. Int J Antimicrob Agents (2013) 0.83
Deletion of the GI-2 integrase and the wbkA flanking transposase improves the stability of Brucella melitensis Rev 1 vaccine. Vet Res (2013) 0.81
Establishment of Chronic Infection: Brucella's Stealth Strategy. Front Cell Infect Microbiol (2016) 0.81
Phospholipase A1 Modulates the Cell Envelope Phospholipid Content of Brucella melitensis, Contributing to Polymyxin Resistance and Pathogenicity. Antimicrob Agents Chemother (2015) 0.77
Structural Studies of Lipopolysaccharide-defective Mutants from Brucella melitensis Identify a Core Oligosaccharide Critical in Virulence. J Biol Chem (2016) 0.77
COX-2 Inhibition Reduces Brucella Bacterial Burden in Draining Lymph Nodes. Front Microbiol (2016) 0.76
Trade-Offs of Escherichia coli Adaptation to an Intracellular Lifestyle in Macrophages. PLoS One (2016) 0.76
Brucella CβG induces a dual pro- and anti-inflammatory response leading to a transient neutrophil recruitment. Virulence (2015) 0.76
Smooth to Rough Dissociation in Brucella: The Missing Link to Virulence. Front Cell Infect Microbiol (2016) 0.76
Chronic Bacterial Pathogens: Mechanisms of Persistence. Microbiol Spectr (2016) 0.76
The BtaF trimeric autotransporter of Brucella suis is involved in attachment to various surfaces, resistance to serum and virulence. PLoS One (2013) 0.75
Genetics and evolution of Yersinia pseudotuberculosis O-specific polysaccharides: a novel pattern of O-antigen diversity. FEMS Microbiol Rev (2017) 0.75
N-Formyl-Perosamine Surface Homopolysaccharides Hinder the Recognition of Brucella abortus by Mouse Neutrophils. Infect Immun (2016) 0.75
A sensitive silver stain for detecting lipopolysaccharides in polyacrylamide gels. Anal Biochem (1982) 36.39
A Toll-like receptor recognizes bacterial DNA. Nature (2000) 26.34
Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J Exp Med (1992) 22.13
Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J Immunol (1999) 16.86
The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature (2009) 8.99
Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2. J Immunol (2000) 6.68
Mycobacteria target DC-SIGN to suppress dendritic cell function. J Exp Med (2003) 5.58
Bacterial polysaccharide synthesis and gene nomenclature. Trends Microbiol (1996) 4.49
Some structural and biological properties of Brucella endotoxin. Infect Immun (1970) 3.26
Francisella tularensis induces aberrant activation of pulmonary dendritic cells. J Immunol (2005) 2.79
A two-component regulatory system playing a critical role in plant pathogens and endosymbionts is present in Brucella abortus and controls cell invasion and virulence. Mol Microbiol (1998) 2.60
Brucella control of dendritic cell maturation is dependent on the TIR-containing protein Btp1. PLoS Pathog (2008) 2.38
Transposon-derived Brucella abortus rough mutants are attenuated and exhibit reduced intracellular survival. Infect Immun (1998) 2.36
Brucella lipopolysaccharide acts as a virulence factor. Curr Opin Microbiol (2005) 2.05
Brucella intracellular life: from invasion to intracellular replication. Vet Microbiol (2002) 1.99
Implication of phagosome-lysosome fusion in restriction of Mycobacterium avium growth in bone marrow macrophages from genetically resistant mice. Infect Immun (1993) 1.98
Generation of the Brucella melitensis ORFeome version 1.1. Genome Res (2004) 1.86
The outer membranes of Brucella spp. are resistant to bactericidal cationic peptides. Infect Immun (1995) 1.82
Brucella abortus uses a stealthy strategy to avoid activation of the innate immune system during the onset of infection. PLoS One (2007) 1.82
Identification and characterization of the Brucella abortus phosphoglucomutase gene: role of lipopolysaccharide in virulence and intracellular multiplication. Infect Immun (2000) 1.70
Rough vaccines in animal brucellosis: structural and genetic basis and present status. Vet Res (2004) 1.68
Surface exposure of outer membrane protein and lipopolysaccharide epitopes in Brucella species studied by enzyme-linked immunosorbent assay and flow cytometry. Infect Immun (1995) 1.54
Microextraction of bacterial lipid A: easy and rapid method for mass spectrometric characterization. J Lipid Res (2005) 1.53
Brucella-Salmonella lipopolysaccharide chimeras are less permeable to hydrophobic probes and more sensitive to cationic peptides and EDTA than are their native Brucella sp. counterparts. J Bacteriol (1996) 1.47
An evolutionary strategy for a stealthy intracellular Brucella pathogen. Immunol Rev (2011) 1.39
Comparative analysis of Brucella serotype A and M and Yersinia enterocolitica O:9 polysaccharides for serological diagnosis of brucellosis in cattle, sheep, and goats. J Clin Microbiol (1993) 1.38
mTOR: taking cues from the immune microenvironment. Immunology (2009) 1.38
Brucellosis vaccines: assessment of Brucella melitensis lipopolysaccharide rough mutants defective in core and O-polysaccharide synthesis and export. PLoS One (2008) 1.37
MD-2 as the target of curcumin in the inhibition of response to LPS. J Leukoc Biol (2007) 1.26
Sodium dodecyl sulfate-polyacrylamide gel electrophoresis and immunoblotting analysis of smooth-lipopolysaccharide heterogeneity among Brucella biovars related to A and M specificities. J Clin Microbiol (1990) 1.18
Brucella abortus and its closest phylogenetic relative, Ochrobactrum spp., differ in outer membrane permeability and cationic peptide resistance. Infect Immun (2000) 1.17
Differential inductions of TNF-alpha and IGTP, IIGP by structurally diverse classic and non-classic lipopolysaccharides. Cell Microbiol (2006) 1.16
Cloning and overexpression of glycosyltransferases that generate the lipopolysaccharide core of Rhizobium leguminosarum. J Biol Chem (1998) 1.16
Gateway-based destination vectors for functional analyses of bacterial ORFeomes: application to the Min system in Brucella abortus. Appl Environ Microbiol (2006) 1.09
Brucella suis prevents human dendritic cell maturation and antigen presentation through regulation of tumor necrosis factor alpha secretion. Infect Immun (2007) 1.08
Salmonella enterica serovar typhimurium-induced maturation of bone marrow-derived dendritic cells. Infect Immun (2000) 1.03
Conformational studies of synthetic lipid A analogues and partial structures by infrared spectroscopy. Biochim Biophys Acta (1997) 1.03
Salmonella enterica serovar Typhimurium interaction with dendritic cells: impact of the sifA gene. Cell Microbiol (2004) 1.01
The differential interaction of Brucella and ochrobactrum with innate immunity reveals traits related to the evolution of stealthy pathogens. PLoS One (2009) 1.01
Temperature dependence of the binding of endotoxins to the polycationic peptides polymyxin B and its nonapeptide. Biophys J (2004) 0.99
Structural similarity between the hydrophobic fluorescent probe and lipid A as a ligand of MD-2. FASEB J (2006) 0.96
Interaction of Brucella suis and Brucella abortus rough strains with human dendritic cells. Infect Immun (2007) 0.95
Mechanism of serum resistance among Brucella abortus isolates. Vet Microbiol (1999) 0.89
Role of lipid A acylation in Yersinia enterocolitica virulence. Infect Immun (2010) 0.88
Brucella abortus ornithine lipids are dispensable outer membrane components devoid of a marked pathogen-associated molecular pattern. PLoS One (2011) 0.84
Brucella evades macrophage killing via VirB-dependent sustained interactions with the endoplasmic reticulum. J Exp Med (2003) 3.23
Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening. EMBO J (2003) 2.87
Cyclic beta-1,2-glucan is a Brucella virulence factor required for intracellular survival. Nat Immunol (2005) 2.51
Brucella control of dendritic cell maturation is dependent on the TIR-containing protein Btp1. PLoS Pathog (2008) 2.38
Brucella evolution and taxonomy. Vet Microbiol (2002) 2.29
Capsule polysaccharide mediates bacterial resistance to antimicrobial peptides. Infect Immun (2004) 2.14
Phosphoethanolamine modification of lipid A in colistin-resistant variants of Acinetobacter baumannii mediated by the pmrAB two-component regulatory system. Antimicrob Agents Chemother (2011) 2.09
Brucella lipopolysaccharide acts as a virulence factor. Curr Opin Microbiol (2005) 2.05
Brucella intracellular life: from invasion to intracellular replication. Vet Microbiol (2002) 1.99
The intracellular fate of Salmonella depends on the recruitment of kinesin. Science (2005) 1.92
Mechanism of endosomal TLR inhibition by antimalarial drugs and imidazoquinolines. J Immunol (2011) 1.83
Brucella abortus uses a stealthy strategy to avoid activation of the innate immune system during the onset of infection. PLoS One (2007) 1.82
Mimivirus giant particles incorporate a large fraction of anonymous and unique gene products. J Virol (2006) 1.76
Internal affairs: investigating the Brucella intracellular lifestyle. FEMS Microbiol Rev (2012) 1.75
Dysregulation of the mevalonate pathway promotes transformation. Proc Natl Acad Sci U S A (2010) 1.71
Brucella coopts the small GTPase Sar1 for intracellular replication. Proc Natl Acad Sci U S A (2005) 1.70
The POM monoclonals: a comprehensive set of antibodies to non-overlapping prion protein epitopes. PLoS One (2008) 1.70
Rough vaccines in animal brucellosis: structural and genetic basis and present status. Vet Res (2004) 1.68
Pathogenic brucellae replicate in human trophoblasts. J Infect Dis (2013) 1.66
Identification of the lipopolysaccharide core of Yersinia pestis and Yersinia pseudotuberculosis as the receptor for bacteriophage φA1122. J Bacteriol (2011) 1.66
Insights into the mode of action of chitosan as an antibacterial compound. Appl Environ Microbiol (2008) 1.60
Interaction of quorum signals with outer membrane lipids: insights into prokaryotic membrane vesicle formation. Mol Microbiol (2008) 1.56
The Salmonella effector protein PipB2 is a linker for kinesin-1. Proc Natl Acad Sci U S A (2006) 1.54
Bacterial manipulation of innate immunity to promote infection. Nat Rev Microbiol (2010) 1.53
Combinational clustering of receptors following stimulation by bacterial products determines lipopolysaccharide responses. Biochem J (2004) 1.52
Peyer's patch dendritic cells sample antigens by extending dendrites through M cell-specific transcellular pores. Gastroenterology (2011) 1.51
Structural model of MD-2 and functional role of its basic amino acid clusters involved in cellular lipopolysaccharide recognition. J Biol Chem (2004) 1.48
Organelle robbery: Brucella interactions with the endoplasmic reticulum. Curr Opin Microbiol (2004) 1.47
Nanobacteria are mineralo fetuin complexes. PLoS Pathog (2008) 1.42
Klebsiella pneumoniae AcrAB efflux pump contributes to antimicrobial resistance and virulence. Antimicrob Agents Chemother (2009) 1.42
An evolutionary strategy for a stealthy intracellular Brucella pathogen. Immunol Rev (2011) 1.39
Defective B cell response to TLR9 ligand (CpG-ODN), Streptococcus pneumoniae and Haemophilus influenzae extracts in common variable immunodeficiency patients. Cell Immunol (2010) 1.39
The translocated Salmonella effector proteins SseF and SseG interact and are required to establish an intracellular replication niche. Infect Immun (2006) 1.39
Coxiella burnetii survival in THP-1 monocytes involves the impairment of phagosome maturation: IFN-gamma mediates its restoration and bacterial killing. J Immunol (2002) 1.38
Essential roles of hydrophobic residues in both MD-2 and toll-like receptor 4 in activation by endotoxin. J Biol Chem (2009) 1.38
Brucellosis vaccines: assessment of Brucella melitensis lipopolysaccharide rough mutants defective in core and O-polysaccharide synthesis and export. PLoS One (2008) 1.37
Salmonella typhimurium SifA effector protein requires its membrane-anchoring C-terminal hexapeptide for its biological function. J Biol Chem (2003) 1.36
Design of a single-chain polypeptide tetrahedron assembled from coiled-coil segments. Nat Chem Biol (2013) 1.32
The Haemophilus ducreyi cytolethal distending toxin induces DNA double-strand breaks and promotes ATM-dependent activation of RhoA. Cell Microbiol (2003) 1.31
Pathogenic bacteria and dead cells are internalized by a unique subset of Peyer's patch dendritic cells that express lysozyme. Gastroenterology (2009) 1.31
Identification and structural characterization of an unusual mycobacterial monomeromycolyl-diacylglycerol. Mol Microbiol (2005) 1.29
Globular domain of the prion protein needs to be unlocked by domain swapping to support prion protein conversion. J Biol Chem (2011) 1.29
DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency. Nucleic Acids Res (2011) 1.28
Enhancement of endotoxin neutralization by coupling of a C12-alkyl chain to a lactoferricin-derived peptide. Biochem J (2005) 1.28
The Rose Bengal Test in human brucellosis: a neglected test for the diagnosis of a neglected disease. PLoS Negl Trop Dis (2011) 1.27
The Haemophilus ducreyi cytolethal distending toxin activates sensors of DNA damage and repair complexes in proliferating and non-proliferating cells. Cell Microbiol (2002) 1.26
MD-2 as the target of curcumin in the inhibition of response to LPS. J Leukoc Biol (2007) 1.26
In search of Brucella abortus type IV secretion substrates: screening and identification of four proteins translocated into host cells through VirB system. Cell Microbiol (2011) 1.26
MyD88, but not toll-like receptors 4 and 2, is required for efficient clearance of Brucella abortus. Infect Immun (2005) 1.24
A second binding site for double-stranded RNA in TLR3 and consequences for interferon activation. Nat Struct Mol Biol (2008) 1.24
Enhancement of antibacterial and lipopolysaccharide binding activities of a human lactoferrin peptide fragment by the addition of acyl chain. J Antimicrob Chemother (2003) 1.24
Identification of a Brucella spp. secreted effector specifically interacting with human small GTPase Rab2. Cell Microbiol (2011) 1.22
Analysis of the networks controlling the antimicrobial-peptide-dependent induction of Klebsiella pneumoniae virulence factors. Infect Immun (2011) 1.19
The lipopolysaccharide of Brucella abortus BvrS/BvrR mutants contains lipid A modifications and has higher affinity for bactericidal cationic peptides. J Bacteriol (2005) 1.17
The uptake of a Klebsiella pneumoniae capsule polysaccharide mutant triggers an inflammatory response by human airway epithelial cells. Microbiology (2006) 1.17
Salmonella detoxifying enzymes are sufficient to cope with the host oxidative burst. Mol Microbiol (2011) 1.17
Differential inductions of TNF-alpha and IGTP, IIGP by structurally diverse classic and non-classic lipopolysaccharides. Cell Microbiol (2006) 1.16
Synthesis of phosphatidylcholine, a typical eukaryotic phospholipid, is necessary for full virulence of the intracellular bacterial parasite Brucella abortus. Cell Microbiol (2006) 1.16
Klebsiella pneumoniae capsule polysaccharide impedes the expression of beta-defensins by airway epithelial cells. Infect Immun (2009) 1.16
Identification of two putative rickettsial adhesins by proteomic analysis. Res Microbiol (2006) 1.16
The glyceraldehyde-3-phosphate dehydrogenase and the small GTPase Rab 2 are crucial for Brucella replication. PLoS Pathog (2009) 1.16
BtpB, a novel Brucella TIR-containing effector protein with immune modulatory functions. Front Cell Infect Microbiol (2013) 1.16
The differential production of cytokines by human Langerhans cells and dermal CD14(+) DCs controls CTL priming. Blood (2012) 1.15
New antiseptic peptides to protect against endotoxin-mediated shock. Antimicrob Agents Chemother (2010) 1.14
Toll-like receptor 4 activation in cancer progression and therapy. Clin Dev Immunol (2011) 1.14
Activation of Rho and Rab GTPases dissociates Brucella abortus internalization from intracellular trafficking. Cell Microbiol (2002) 1.14
Intracellular adaptation of Brucella abortus. J Proteome Res (2009) 1.13
What have we learned from brucellosis in the mouse model? Vet Res (2012) 1.13
The biosynthesis and biological role of lipopolysaccharide O-antigens of pathogenic Yersiniae. Carbohydr Res (2003) 1.12
Biophysical characterization of endotoxin inactivation by NK-2, an antimicrobial peptide derived from mammalian NK-lysin. Antimicrob Agents Chemother (2004) 1.11
Lipopolysaccharide regions involved in the activation of Escherichia coli outer membrane protease OmpT. Eur J Biochem (2002) 1.11
DNA polymorphism analysis of Brucella lipopolysaccharide genes reveals marked differences in O-polysaccharide biosynthetic genes between smooth and rough Brucella species and novel species-specific markers. BMC Microbiol (2009) 1.11
Contrasting roles of macrophages and dendritic cells in controlling initial pulmonary Brucella infection. Eur J Immunol (2010) 1.11
Monoclonal antibody against a peptide of human prion protein discriminates between Creutzfeldt-Jacob's disease-affected and normal brain tissue. J Biol Chem (2003) 1.09
Taxanes inhibit human TLR4 signaling by binding to MD-2. FEBS Lett (2008) 1.09
Extensive cell envelope modulation is associated with virulence in Brucella abortus. J Proteome Res (2007) 1.09
Molecular motors hijacking by intracellular pathogens. Cell Microbiol (2006) 1.08