Published in Science on May 20, 2005
Role of Rab GTPases in membrane traffic and cell physiology. Physiol Rev (2011) 5.20
Type III secretion systems and disease. Clin Microbiol Rev (2007) 2.61
Salmonella takes control: effector-driven manipulation of the host. Curr Opin Microbiol (2009) 2.41
Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation. Cell Host Microbe (2008) 2.21
During infection of epithelial cells Salmonella enterica serovar Typhimurium undergoes a time-dependent transcriptional adaptation that results in simultaneous expression of three type 3 secretion systems. Cell Microbiol (2007) 1.94
The Salmonella-containing vacuole: moving with the times. Curr Opin Microbiol (2008) 1.80
Pathogens and polymers: microbe-host interactions illuminate the cytoskeleton. J Cell Biol (2011) 1.63
The Salmonella effector protein PipB2 is a linker for kinesin-1. Proc Natl Acad Sci U S A (2006) 1.54
Salmonella enterica serovar Typhimurium skills to succeed in the host: virulence and regulation. Clin Microbiol Rev (2013) 1.52
The protein SdhA maintains the integrity of the Legionella-containing vacuole. Proc Natl Acad Sci U S A (2012) 1.47
TBK1 protects vacuolar integrity during intracellular bacterial infection. PLoS Pathog (2007) 1.43
SCAMP3 is a component of the Salmonella-induced tubular network and reveals an interaction between bacterial effectors and post-Golgi trafficking. Cell Microbiol (2009) 1.43
Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics. Nat Struct Mol Biol (2009) 1.41
Salmonella Effectors SseF and SseG Interact with Mammalian Protein ACBD3 (GCP60) To Anchor Salmonella-Containing Vacuoles at the Golgi Network. MBio (2016) 1.39
The translocated Salmonella effector proteins SseF and SseG interact and are required to establish an intracellular replication niche. Infect Immun (2006) 1.39
Arl8 and SKIP act together to link lysosomes to kinesin-1. Dev Cell (2011) 1.37
Dynamic behavior of Salmonella-induced membrane tubules in epithelial cells. Traffic (2008) 1.31
The Salmonella effector PipB2 affects late endosome/lysosome distribution to mediate Sif extension. Mol Biol Cell (2005) 1.27
SteC is a Salmonella kinase required for SPI-2-dependent F-actin remodelling. Cell Microbiol (2007) 1.26
Salmonella effector proteins and host-cell responses. Cell Mol Life Sci (2011) 1.23
Functional analysis of the Salmonella pathogenicity island 2-mediated inhibition of antigen presentation in dendritic cells. Infect Immun (2008) 1.23
Salmonella SPI1 effector SipA persists after entry and cooperates with a SPI2 effector to regulate phagosome maturation and intracellular replication. Cell Host Microbe (2007) 1.22
Imaging type-III secretion reveals dynamics and spatial segregation of Salmonella effectors. Nat Methods (2010) 1.18
Potent host-directed small-molecule inhibitors of myxovirus RNA-dependent RNA-polymerases. PLoS One (2011) 1.18
Salmonella effectors: important players modulating host cell function during infection. Cell Microbiol (2011) 1.18
Subversion of membrane transport pathways by vacuolar pathogens. J Cell Biol (2011) 1.16
The SPI-2 type III secretion system restricts motility of Salmonella-containing vacuoles. Cell Microbiol (2007) 1.15
Salmonella enterica response regulator SsrB relieves H-NS silencing by displacing H-NS bound in polymerization mode and directly activates transcription. J Biol Chem (2010) 1.13
Identification of Mycobacterium avium pathogenicity island important for macrophage and amoeba infection. Proc Natl Acad Sci U S A (2007) 1.13
Salmonellae interactions with host processes. Nat Rev Microbiol (2015) 1.11
Flagella facilitate escape of Salmonella from oncotic macrophages. J Bacteriol (2007) 1.10
The current Salmonella-host interactome. Proteomics Clin Appl (2011) 1.08
Bacterial guanine nucleotide exchange factors SopE-like and WxxxE effectors. Infect Immun (2010) 1.07
Quantitative mass spectrometry catalogues Salmonella pathogenicity island-2 effectors and identifies their cognate host binding partners. J Biol Chem (2011) 1.06
A Rab-centric perspective of bacterial pathogen-occupied vacuoles. Cell Host Microbe (2013) 1.05
Manipulation of host membrane machinery by bacterial pathogens. Curr Opin Cell Biol (2010) 1.05
The Salmonella virulence protein SifA is a G protein antagonist. Proc Natl Acad Sci U S A (2008) 1.03
Role for myosin II in regulating positioning of Salmonella-containing vacuoles and intracellular replication. Infect Immun (2008) 1.02
The professional phagocyte Dictyostelium discoideum as a model host for bacterial pathogens. Curr Drug Targets (2011) 1.02
The virulence protein SopD2 regulates membrane dynamics of Salmonella-containing vacuoles. PLoS Pathog (2010) 1.00
Bacterial pathogens commandeer Rab GTPases to establish intracellular niches. Traffic (2012) 0.99
Salmonella - at home in the host cell. Front Microbiol (2011) 0.99
Structural basis for kinesin-1:cargo recognition. Science (2013) 0.97
Prison break: pathogens' strategies to egress from host cells. Microbiol Mol Biol Rev (2012) 0.97
Rapid escape of the dot/icm mutants of Legionella pneumophila into the cytosol of mammalian and protozoan cells. Infect Immun (2007) 0.97
A kinesin-1 binding motif in vaccinia virus that is widespread throughout the human genome. EMBO J (2011) 0.96
Mimicking GEFs: a common theme for bacterial pathogens. Cell Microbiol (2011) 0.93
Mechanisms used by virulent Salmonella to impair dendritic cell function and evade adaptive immunity. Immunology (2012) 0.92
Interspecies communication in the gut, from bacterial delivery to host-cell response. J Physiol (2011) 0.91
Differentially evolved genes of Salmonella pathogenicity islands: insights into the mechanism of host specificity in Salmonella. PLoS One (2008) 0.90
Enteropathogenic Escherichia coli, Samonella, Shigella and Yersinia: cellular aspects of host-bacteria interactions in enteric diseases. Gut Pathog (2010) 0.90
Salmonella-containing vacuoles display centrifugal movement associated with cell-to-cell transfer in epithelial cells. Infect Immun (2008) 0.88
Targeting of host organelles by pathogenic bacteria: a sophisticated subversion strategy. Nat Rev Microbiol (2015) 0.88
Reorganization of the endosomal system in Salmonella-infected cells: the ultrastructure of Salmonella-induced tubular compartments. PLoS Pathog (2014) 0.87
Maintenance of vacuole integrity by bacterial pathogens. Curr Opin Microbiol (2013) 0.87
Interaction between the SifA virulence factor and its host target SKIP is essential for Salmonella pathogenesis. J Biol Chem (2009) 0.87
The Salmonella effector SteA contributes to the control of membrane dynamics of Salmonella-containing vacuoles. Infect Immun (2014) 0.83
A Salmonella typhimurium-translocated glycerophospholipid:cholesterol acyltransferase promotes virulence by binding to the RhoA protein switch regions. J Biol Chem (2012) 0.82
Rab1A regulates anterograde melanosome transport by recruiting kinesin-1 to melanosomes through interaction with SKIP. Sci Rep (2015) 0.79
Involvement of TIP60 acetyltransferase in intracellular Salmonella replication. BMC Microbiol (2010) 0.78
Mechanisms and functions of lysosome positioning. J Cell Sci (2016) 0.78
The Salmonella effector protein SifA plays a dual role in virulence. Sci Rep (2015) 0.77
BORC Functions Upstream of Kinesins 1 and 3 to Coordinate Regional Movement of Lysosomes along Different Microtubule Tracks. Cell Rep (2016) 0.76
Bacterial scaffolds assemble novel higher-order complexes to reengineer eukaryotic cell processes. Sci Signal (2011) 0.76
Expression of the Salmonella spp. virulence factor SifA in yeast alters Rho1 activity on peroxisomes. Mol Biol Cell (2010) 0.76
PLEKHM2 mutation leads to abnormal localization of lysosomes, impaired autophagy flux and associates with recessive dilated cardiomyopathy and left ventricular noncompaction. Hum Mol Genet (2015) 0.76
How Bacteria Subvert Animal Cell Structure and Function. Annu Rev Cell Dev Biol (2016) 0.75
Cytosolic Access of Intracellular Bacterial Pathogens: The Shigella Paradigm. Front Cell Infect Microbiol (2016) 0.75
What the SIF Is Happening-The Role of Intracellular Salmonella-Induced Filaments. Front Cell Infect Microbiol (2017) 0.75
Transcriptomes and expression profiling of deep-sea corals from the Red Sea provide insight into the biology of azooxanthellate corals. Sci Rep (2017) 0.75
Electrical stimulation of the anterior nucleus of thalamus for treatment of refractory epilepsy. Epilepsia (2010) 5.64
Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis. Proc Natl Acad Sci U S A (2010) 4.57
Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin. Nat Immunol (2008) 4.08
In vivo negative selection screen identifies genes required for Francisella virulence. Proc Natl Acad Sci U S A (2007) 3.73
PDZ domain proteins: plug and play! Sci STKE (2003) 3.38
Brucella evades macrophage killing via VirB-dependent sustained interactions with the endoplasmic reticulum. J Exp Med (2003) 3.23
Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening. EMBO J (2003) 2.87
Cyclic beta-1,2-glucan is a Brucella virulence factor required for intracellular survival. Nat Immunol (2005) 2.51
Brucella control of dendritic cell maturation is dependent on the TIR-containing protein Btp1. PLoS Pathog (2008) 2.38
Brucella lipopolysaccharide acts as a virulence factor. Curr Opin Microbiol (2005) 2.05
Scrib controls Cdc42 localization and activity to promote cell polarization during astrocyte migration. Curr Biol (2006) 2.03
Mammalian Scribble forms a tight complex with the betaPIX exchange factor. Curr Biol (2004) 1.89
Staphylococcus aureus hemolysins, bi-component leukocidins, and cytolytic peptides: a redundant arsenal of membrane-damaging virulence factors? Front Cell Infect Microbiol (2012) 1.84
T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow. J Exp Med (2014) 1.82
Poly(ADP-ribose) polymerase-1 mRNA expression in human breast cancer: a meta-analysis. Breast Cancer Res Treat (2010) 1.81
A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling. J Biol Chem (2005) 1.81
Contribution of flagellin pattern recognition to intestinal inflammation during Salmonella enterica serotype typhimurium infection. Infect Immun (2009) 1.79
Mimivirus giant particles incorporate a large fraction of anonymous and unique gene products. J Virol (2006) 1.76
Internal affairs: investigating the Brucella intracellular lifestyle. FEMS Microbiol Rev (2012) 1.75
Redundant hydrogen peroxide scavengers contribute to Salmonella virulence and oxidative stress resistance. J Bacteriol (2009) 1.75
Junctional recruitment of mammalian Scribble relies on E-cadherin engagement. Oncogene (2005) 1.73
Brucella coopts the small GTPase Sar1 for intracellular replication. Proc Natl Acad Sci U S A (2005) 1.70
Semaphorin 3E suppresses tumor cell death triggered by the plexin D1 dependence receptor in metastatic breast cancers. Cancer Cell (2013) 1.68
Pathogenic brucellae replicate in human trophoblasts. J Infect Dis (2013) 1.66
The staphylococcal toxin Panton-Valentine Leukocidin targets human C5a receptors. Cell Host Microbe (2013) 1.66
The Salmonella effector protein PipB2 is a linker for kinesin-1. Proc Natl Acad Sci U S A (2006) 1.54
Bacterial manipulation of innate immunity to promote infection. Nat Rev Microbiol (2010) 1.53
Peyer's patch dendritic cells sample antigens by extending dendrites through M cell-specific transcellular pores. Gastroenterology (2011) 1.51
The NOD2-RICK complex signals from the plasma membrane. J Biol Chem (2007) 1.50
Apicobasal polarity complexes. J Cell Sci (2005) 1.48
Organelle robbery: Brucella interactions with the endoplasmic reticulum. Curr Opin Microbiol (2004) 1.47
ZNF703 gene amplification at 8p12 specifies luminal B breast cancer. EMBO Mol Med (2011) 1.47
Nanobacteria are mineralo fetuin complexes. PLoS Pathog (2008) 1.42
The hScrib/Dlg apico-basal control complex is differentially targeted by HPV-16 and HPV-18 E6 proteins. Oncogene (2005) 1.40
An evolutionary strategy for a stealthy intracellular Brucella pathogen. Immunol Rev (2011) 1.39
The translocated Salmonella effector proteins SseF and SseG interact and are required to establish an intracellular replication niche. Infect Immun (2006) 1.39
Coxiella burnetii survival in THP-1 monocytes involves the impairment of phagosome maturation: IFN-gamma mediates its restoration and bacterial killing. J Immunol (2002) 1.38
Brucellosis vaccines: assessment of Brucella melitensis lipopolysaccharide rough mutants defective in core and O-polysaccharide synthesis and export. PLoS One (2008) 1.37
The Amot/Patj/Syx signaling complex spatially controls RhoA GTPase activity in migrating endothelial cells. Blood (2008) 1.36
Salmonella typhimurium SifA effector protein requires its membrane-anchoring C-terminal hexapeptide for its biological function. J Biol Chem (2003) 1.36
Pathogenic bacteria and dead cells are internalized by a unique subset of Peyer's patch dendritic cells that express lysozyme. Gastroenterology (2009) 1.31
Identification and structural characterization of an unusual mycobacterial monomeromycolyl-diacylglycerol. Mol Microbiol (2005) 1.29
Down-regulation of ECRG4, a candidate tumor suppressor gene, in human breast cancer. PLoS One (2011) 1.27
In search of Brucella abortus type IV secretion substrates: screening and identification of four proteins translocated into host cells through VirB system. Cell Microbiol (2011) 1.26
Interactions between human NK cells and macrophages in response to Salmonella infection. J Immunol (2009) 1.23
Identification of a Brucella spp. secreted effector specifically interacting with human small GTPase Rab2. Cell Microbiol (2011) 1.22
Francisella tularensis: activation of the inflammasome. Ann N Y Acad Sci (2007) 1.22
The association of stigma with self-management and perceptions of health care among adults with epilepsy. Epilepsy Behav (2003) 1.20
The Crohn's disease-associated adherent-invasive Escherichia coli strain LF82 replicates in mature phagolysosomes within J774 macrophages. Cell Microbiol (2006) 1.18
Regulation of LKB1/STRAD localization and function by E-cadherin. Curr Biol (2008) 1.18
Basolateral targeting by leucine-rich repeat domains in epithelial cells. EMBO Rep (2003) 1.17
The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition. PLoS Pathog (2012) 1.17
Cross-talk between Staphylococcus aureus leukocidins-intoxicated macrophages and lung epithelial cells triggers chemokine secretion in an inflammasome-dependent manner. Cell Microbiol (2012) 1.17
Scrib regulates PAK activity during the cell migration process. Hum Mol Genet (2008) 1.17
Salmonella-induced tubular networks. Trends Microbiol (2011) 1.17
Salmonella detoxifying enzymes are sufficient to cope with the host oxidative burst. Mol Microbiol (2011) 1.17
Differential inductions of TNF-alpha and IGTP, IIGP by structurally diverse classic and non-classic lipopolysaccharides. Cell Microbiol (2006) 1.16
Identification of two putative rickettsial adhesins by proteomic analysis. Res Microbiol (2006) 1.16
The glyceraldehyde-3-phosphate dehydrogenase and the small GTPase Rab 2 are crucial for Brucella replication. PLoS Pathog (2009) 1.16
BtpB, a novel Brucella TIR-containing effector protein with immune modulatory functions. Front Cell Infect Microbiol (2013) 1.16
The differential production of cytokines by human Langerhans cells and dermal CD14(+) DCs controls CTL priming. Blood (2012) 1.15
Activation of Rho and Rab GTPases dissociates Brucella abortus internalization from intracellular trafficking. Cell Microbiol (2002) 1.14
Primary cilium migration depends on G-protein signalling control of subapical cytoskeleton. Nat Cell Biol (2013) 1.13
A polymorphism of EGFR extracellular domain is associated with progression free-survival in metastatic colorectal cancer patients receiving cetuximab-based treatment. BMC Cancer (2008) 1.13
Protein tyrosine kinase 7 has a conserved role in Wnt/β-catenin canonical signalling. EMBO Rep (2010) 1.13
The cell polarity PTK7 receptor acts as a modulator of the chemotherapeutic response in acute myeloid leukemia and impairs clinical outcome. Blood (2010) 1.11
Contrasting roles of macrophages and dendritic cells in controlling initial pulmonary Brucella infection. Eur J Immunol (2010) 1.11
Thyrotropin receptor trafficking relies on the hScrib-betaPIX-GIT1-ARF6 pathway. EMBO J (2005) 1.10
Angiomotin-like protein 1 controls endothelial polarity and junction stability during sprouting angiogenesis. Circ Res (2009) 1.10
Hook2 is involved in the morphogenesis of the primary cilium. Mol Biol Cell (2011) 1.08
hScrib interacts with ZO-2 at the cell-cell junctions of epithelial cells. FEBS Lett (2005) 1.08
Molecular motors hijacking by intracellular pathogens. Cell Microbiol (2006) 1.08
Helicobacter pylori impairs murine dendritic cell responses to infection. PLoS One (2010) 1.08
The Brucella abortus phosphoglycerate kinase mutant is highly attenuated and induces protection superior to that of vaccine strain 19 in immunocompromised and immunocompetent mice. Infect Immun (2010) 1.08
Improved methods for producing outer membrane vesicles in Gram-negative bacteria. Res Microbiol (2004) 1.05
Interaction between Erbin and a Catenin-related protein in epithelial cells. J Biol Chem (2001) 1.05
The LAP family: a phylogenetic point of view. Trends Genet (2002) 1.05
Salmonella regulates polyubiquitination and surface expression of MHC class II antigens. Proc Natl Acad Sci U S A (2009) 1.05
Survival of Tropheryma whipplei, the agent of Whipple's disease, requires phagosome acidification. Infect Immun (2002) 1.05
Protein profiling of human breast tumor cells identifies novel biomarkers associated with molecular subtypes. Mol Cell Proteomics (2008) 1.04
Asparagine assimilation is critical for intracellular replication and dissemination of Francisella. Cell Microbiol (2013) 1.04
Salmonella T3SSs: successful mission of the secret(ion) agents. Curr Opin Microbiol (2013) 1.03
Erbin regulates mitogen-activated protein (MAP) kinase activation and MAP kinase-dependent interactions between Merlin and adherens junction protein complexes in Schwann cells. J Biol Chem (2005) 1.02
The virulence protein SopD2 regulates membrane dynamics of Salmonella-containing vacuoles. PLoS Pathog (2010) 1.00
Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH. J Biol Chem (2002) 1.00
Transcriptome analysis of the Brucella abortus BvrR/BvrS two-component regulatory system. PLoS One (2010) 1.00
SKIP, the host target of the Salmonella virulence factor SifA, promotes kinesin-1-dependent vacuolar membrane exchanges. Traffic (2010) 1.00
Erbin regulates NRG1 signaling and myelination. Proc Natl Acad Sci U S A (2009) 0.98