Published in J Invest Dermatol on October 01, 2012
Identification of rare recurrent copy number variants in high-risk autism families and their prevalence in a large ASD population. PLoS One (2013) 1.03
Cellular dissection of psoriasis for transcriptome analyses and the post-GWAS era. BMC Med Genomics (2014) 0.93
Crosstalk between keratinocytes and T cells in a 3D microenvironment: a model to study inflammatory skin diseases. J Invest Dermatol (2013) 0.84
A GRHL3-regulated repair pathway suppresses immune-mediated epidermal hyperplasia. J Clin Invest (2014) 0.84
Update on psoriasis immunopathogenesis and targeted immunotherapy. Semin Immunopathol (2015) 0.79
Abnormal epidermal barrier recovery in uninvolved skin supports the notion of an epidermal pathogenesis of psoriasis. J Invest Dermatol (2014) 0.76
Conditional PDK1 Ablation Promotes Epidermal and T-Cell-Mediated Dysfunctions Leading to Inflammatory Skin Disease. J Invest Dermatol (2015) 0.75
The psoriasis-associated deletion of late cornified envelope genes LCE3B and LCE3C has been maintained under balancing selection since Human Denisovan divergence. BMC Evol Biol (2016) 0.75
Copy number variations in Saudi family with intellectual disability and epilepsy. BMC Genomics (2016) 0.75
Worldwide population distribution of the common LCE3C-LCE3B deletion associated with psoriasis and other autoimmune disorders. BMC Genomics (2013) 0.75
Psoriasis-associated Late Cornified Envelope (LCE) Proteins Have Antibacterial Activity. J Invest Dermatol (2017) 0.75
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet (2010) 8.48
Psoriasis is associated with increased beta-defensin genomic copy number. Nat Genet (2007) 8.07
Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis. Nat Genet (2009) 5.93
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nat Genet (2012) 4.13
Accurate, high-throughput typing of copy number variation using paralogue ratios from dispersed repeats. Nucleic Acids Res (2006) 2.64
Neuromuscular involvement in various types of Ehlers-Danlos syndrome. Ann Neurol (2009) 2.26
Compound heterozygous mutations of the TNXB gene cause primary myopathy. Neuromuscul Disord (2013) 2.01
Meta-analysis confirms the LCE3C_LCE3B deletion as a risk factor for psoriasis in several ethnic groups and finds interaction with HLA-Cw6. J Invest Dermatol (2010) 1.82
High expression levels of keratinocyte antimicrobial proteins in psoriasis compared with atopic dermatitis. J Invest Dermatol (2005) 1.78
Deficiency of tenascin-X causes abnormalities in dermal elastic fiber morphology. J Invest Dermatol (2004) 1.58
Increased angiogenesis and blood vessel maturation in acellular collagen-heparin scaffolds containing both FGF2 and VEGF. Biomaterials (2006) 1.44
Replication of LCE3C-LCE3B CNV as a risk factor for psoriasis and analysis of interaction with other genetic risk factors. J Invest Dermatol (2009) 1.26
Haploinsufficiency of TNXB is associated with hypermobility type of Ehlers-Danlos syndrome. Am J Hum Genet (2003) 1.26
Coal tar induces AHR-dependent skin barrier repair in atopic dermatitis. J Clin Invest (2013) 1.23
Transcriptional response of bronchial epithelial cells to Pseudomonas aeruginosa: identification of early mediators of host defense. Physiol Genomics (2005) 1.23
Tenascin-X, collagen, elastin, and the Ehlers-Danlos syndrome. Am J Med Genet C Semin Med Genet (2005) 1.16
Microbiome dynamics of human epidermis following skin barrier disruption. Genome Biol (2012) 1.15
Joint hypermobility syndromes: the pathophysiologic role of tenascin-X gene defects. Arthritis Rheum (2004) 1.13
Cystatin M/E is a high affinity inhibitor of cathepsin V and cathepsin L by a reactive site that is distinct from the legumain-binding site. A novel clue for the role of cystatin M/E in epidermal cornification. J Biol Chem (2006) 1.10
Development and validation of human psoriatic skin equivalents. Am J Pathol (2008) 1.09
Psoriasis risk genes of the late cornified envelope-3 group are distinctly expressed compared with genes of other LCE groups. Am J Pathol (2011) 1.07
Beta-defensin-2 protein is a serum biomarker for disease activity in psoriasis and reaches biologically relevant concentrations in lesional skin. PLoS One (2009) 1.06
Accuracy and differential bias in copy number measurement of CCL3L1 in association studies with three auto-immune disorders. BMC Genomics (2011) 1.06
Attenuation of melanoma invasion by a secreted variant of activated leukocyte cell adhesion molecule. Cancer Res (2008) 1.03
Human single-chain antibodies reactive with native chondroitin sulfate detect chondroitin sulfate alterations in melanoma and psoriasis. J Invest Dermatol (2004) 1.03
A novel translation re-initiation mechanism for the p63 gene revealed by amino-terminal truncating mutations in Rapp-Hodgkin/Hay-Wells-like syndromes. Hum Mol Genet (2008) 1.02
Association of β-defensin copy number and psoriasis in three cohorts of European origin. J Invest Dermatol (2012) 1.02
Skin microbiome imbalance in patients with STAT1/STAT3 defects impairs innate host defense responses. J Innate Immun (2013) 1.02
Wound healing in tenascin-X deficient mice suggests that tenascin-X is involved in matrix maturation rather than matrix deposition. Connect Tissue Res (2007) 0.98
Microbiome and skin diseases. Curr Opin Allergy Clin Immunol (2013) 0.97
A null mutation in the cystatin M/E gene of ichq mice causes juvenile lethality and defects in epidermal cornification. Hum Mol Genet (2002) 0.97
A comprehensive analysis of pattern recognition receptors in normal and inflamed human epidermis: upregulation of dectin-1 in psoriasis. J Invest Dermatol (2010) 0.97
A proteomics platform combining depletion, multi-lectin affinity chromatography (M-LAC), and isoelectric focusing to study the breast cancer proteome. Anal Chem (2011) 0.96
Interactions of human tenascin-X domains with dermal extracellular matrix molecules. Arch Dermatol Res (2006) 0.96
Rho kinase inhibitor Y-27632 prolongs the life span of adult human keratinocytes, enhances skin equivalent development, and facilitates lentiviral transduction. Tissue Eng Part A (2012) 0.96
Differential gene expression in premalignant human epidermis revealed by cluster analysis of serial analysis of gene expression (SAGE) libraries. FASEB J (2001) 0.95
Deletion of Late Cornified Envelope 3B and 3C genes is not associated with atopic dermatitis. J Invest Dermatol (2010) 0.94
Tumor necrosis factor related apoptosis inducing ligand triggers apoptosis in dividing but not in differentiating human epidermal keratinocytes. J Invest Dermatol (2003) 0.93
Hypertrophic scar formation is associated with an increased number of epidermal Langerhans cells. J Pathol (2004) 0.92
Type 2 helper T-cell cytokines induce morphologic and molecular characteristics of atopic dermatitis in human skin equivalent. Am J Pathol (2011) 0.92
A partial transcriptome of human epidermis. Genomics (2002) 0.90
Host defense effector molecules in mucosal secretions. FEMS Immunol Med Microbiol (2005) 0.90
Discovery of small molecule vanin inhibitors: new tools to study metabolism and disease. ACS Chem Biol (2013) 0.90
Immunohistochemical expression of SKALP/elafin in squamous cell carcinoma of human lung. Oncol Rep (2002) 0.89
Drosomycin-like defensin, a human homologue of Drosophila melanogaster drosomycin with antifungal activity. Antimicrob Agents Chemother (2008) 0.89
Strong induction of AIM2 expression in human epidermis in acute and chronic inflammatory skin conditions. Exp Dermatol (2012) 0.89
Sustained efficacy of the monoclonal anti-interleukin-1 beta antibody canakinumab in a 9-month trial in Schnitzler's syndrome. Ann Rheum Dis (2012) 0.88
Expression of the vanin gene family in normal and inflamed human skin: induction by proinflammatory cytokines. J Invest Dermatol (2009) 0.88
The biology of cystatin M/E and its cognate target proteases. J Invest Dermatol (2009) 0.88
Genetically programmed differences in epidermal host defense between psoriasis and atopic dermatitis patients. PLoS One (2008) 0.87
Colocalization of cystatin M/E and cathepsin V in lamellar granules and corneodesmosomes suggests a functional role in epidermal differentiation. J Invest Dermatol (2006) 0.87
Phenotypical and functional differences in germinative subpopulations derived from normal and psoriatic epidermis. J Invest Dermatol (2005) 0.86
Transcriptional regulation of the elafin gene in human keratinocytes. J Invest Dermatol (2003) 0.86
APR-246/PRIMA-1(MET) rescues epidermal differentiation in skin keratinocytes derived from EEC syndrome patients with p63 mutations. Proc Natl Acad Sci U S A (2013) 0.86
Effect of daily stressors on psoriasis: a prospective study. J Invest Dermatol (2009) 0.86
Evidence that unrestricted legumain activity is involved in disturbed epidermal cornification in cystatin M/E deficient mice. Hum Mol Genet (2004) 0.86
The cystatin M/E-cathepsin L balance is essential for tissue homeostasis in epidermis, hair follicles, and cornea. FASEB J (2010) 0.85
Colocalization of cystatin M/E and its target proteases suggests a role in terminal differentiation of human hair follicle and nail. J Invest Dermatol (2008) 0.84
Comparison of antiproliferative effects of experimental and established antipsoriatic drugs on human keratinocytes, using a simple 96-well-plate assay. In Vitro Cell Dev Biol Anim (2003) 0.83
Increased expression of carbonic anhydrase II (CA II) in lesional skin of atopic dermatitis: regulation by Th2 cytokines. J Invest Dermatol (2007) 0.83
Successful canakinumab treatment identifies IL-1β as a pivotal mediator in Schnitzler syndrome. J Allergy Clin Immunol (2011) 0.82
Keratinocytes drive melanoma invasion in a reconstructed skin model. Melanoma Res (2010) 0.81
An overview of methods for the in vivo evaluation of tissue-engineered skin constructs. Tissue Eng Part B Rev (2010) 0.81
An in vitro wound healing model for evaluation of dermal substitutes. Wound Repair Regen (2013) 0.80
The human cystatin M/E gene (CST6): exclusion candidate gene for harlequin ichthyosis. J Invest Dermatol (2003) 0.79
Combination of pantothenamides with vanin inhibitors as a novel antibiotic strategy against gram-positive bacteria. Antimicrob Agents Chemother (2013) 0.78
Identification of avarol derivatives as potential antipsoriatic drugs using an in vitro model for keratinocyte growth and differentiation. Life Sci (2006) 0.78
A simple technique for high-throughput screening of drugs that modulate normal and psoriasis-like differentiation in cultured human keratinocytes. Skin Pharmacol Appl Skin Physiol (2002) 0.78
Transcriptomics and proteomics of human skin. Brief Funct Genomic Proteomic (2003) 0.78
Well-defined clinical presentation of Ehlers-Danlos syndrome in patients with tenascin-X deficiency: a report of four cases. Clin Dysmorphol (2012) 0.78
Co-culture of healthy human keratinocytes and T-cells promotes keratinocyte chemokine production and RORγt-positive IL-17 producing T-cell populations. J Dermatol Sci (2012) 0.78
Pattern recognition receptors in infectious skin diseases. Microbes Infect (2012) 0.78