Published in Am J Med Genet C Semin Med Genet on November 15, 2005
Collagen fibrillogenesis: fibronectin, integrins, and minor collagens as organizers and nucleators. Curr Opin Cell Biol (2008) 2.50
Heart valve development: regulatory networks in development and disease. Circ Res (2009) 2.41
Distinct genetic loci control plasma HIV-RNA and cellular HIV-DNA levels in HIV-1 infection: the ANRS Genome Wide Association 01 study. PLoS One (2008) 2.14
TNXB mutations can cause vesicoureteral reflux. J Am Soc Nephrol (2013) 1.59
Diet, ageing and genetic factors in the pathogenesis of diverticular disease. World J Gastroenterol (2009) 1.46
Tenascin-X, collagen, and Ehlers-Danlos syndrome: tenascin-X gene defects can protect against adverse cardiovascular events. Med Hypotheses (2013) 1.42
Regulation of collagen fibril nucleation and initial fibril assembly involves coordinate interactions with collagens V and XI in developing tendon. J Biol Chem (2011) 1.14
Collagen V is a dominant regulator of collagen fibrillogenesis: dysfunctional regulation of structure and function in a corneal-stroma-specific Col5a1-null mouse model. J Cell Sci (2011) 1.00
Spontaneous rupture of the spleen in type IV Ehlers-Danlos syndrome: report of a case. Surg Today (2009) 0.89
Tenascin-X is a novel diagnostic marker of malignant mesothelioma. Am J Surg Pathol (2009) 0.87
Lysyl Oxidase Activity Is Required for Ordered Collagen Fibrillogenesis by Tendon Cells. J Biol Chem (2015) 0.86
Tenascin-C and mechanotransduction in the development and diseases of cardiovascular system. Front Physiol (2014) 0.86
Tenascin-X: beyond the architectural function. Cell Adh Migr (2015) 0.83
The phenotypic spectrum of contiguous deletion of CYP21A2 and tenascin XB: quadricuspid aortic valve and other midline defects. Am J Med Genet A (2009) 0.83
Pericellular proteins of the developing mouse tendon: a proteomic analysis. Connect Tissue Res (2011) 0.83
Regulation of tenascin expression in bone. J Cell Biochem (2011) 0.82
Vesicoureteral reflux and the extracellular matrix connection. Pediatr Nephrol (2016) 0.78
Analysis of obstetric complications and uterine connective tissue in tenascin-X-deficient humans and mice. Cell Tissue Res (2008) 0.77
Phenotypic effects of Ehlers-Danlos syndrome-associated mutation on the FnIII domain of tenascin-X. Protein Sci (2010) 0.76
Transcriptional regulation of tenascin genes. Cell Adh Migr (2015) 0.76
Associations of 6p21.3 Region with Age-related Macular Degeneration and Polypoidal Choroidal Vasculopathy. Sci Rep (2016) 0.75
Identification of the novel localization of tenascinX in the monkey choroid plexus and comparison with the mouse. Eur J Histochem (2009) 0.75
Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis. Hepatology (2007) 9.44
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet (2010) 8.48
Psoriasis is associated with increased beta-defensin genomic copy number. Nat Genet (2007) 8.07
Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis. Nat Genet (2009) 5.93
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nat Genet (2012) 4.13
Accurate, high-throughput typing of copy number variation using paralogue ratios from dispersed repeats. Nucleic Acids Res (2006) 2.64
Hepatitis B virus genotypes in the United States: results of a nationwide study. Gastroenterology (2003) 2.38
Neuromuscular involvement in various types of Ehlers-Danlos syndrome. Ann Neurol (2009) 2.26
Effect of lamivudine treatment on survival of 309 North American patients awaiting liver transplantation for chronic hepatitis B. Liver Transpl (2002) 2.25
Pathogen inactivation: making decisions about new technologies. Report of a consensus conference. Transfusion (2007) 2.19
Compound heterozygous mutations of the TNXB gene cause primary myopathy. Neuromuscul Disord (2013) 2.01
Meta-analysis confirms the LCE3C_LCE3B deletion as a risk factor for psoriasis in several ethnic groups and finds interaction with HLA-Cw6. J Invest Dermatol (2010) 1.82
High expression levels of keratinocyte antimicrobial proteins in psoriasis compared with atopic dermatitis. J Invest Dermatol (2005) 1.78
Utilization of and adherence to the gastroenterology core curriculum on hepatology training during a gastrointestinal fellowship. Clin Gastroenterol Hepatol (2008) 1.72
Deficiency of tenascin-X causes abnormalities in dermal elastic fiber morphology. J Invest Dermatol (2004) 1.58
Prevalence of HBV precore/core promoter variants in the United States. Hepatology (2003) 1.47
Increased angiogenesis and blood vessel maturation in acellular collagen-heparin scaffolds containing both FGF2 and VEGF. Biomaterials (2006) 1.44
Replication of LCE3C-LCE3B CNV as a risk factor for psoriasis and analysis of interaction with other genetic risk factors. J Invest Dermatol (2009) 1.26
Haploinsufficiency of TNXB is associated with hypermobility type of Ehlers-Danlos syndrome. Am J Hum Genet (2003) 1.26
Compliance with practice guidelines and risk of a first esophageal variceal hemorrhage in patients with cirrhosis. Clin Gastroenterol Hepatol (2010) 1.23
Coal tar induces AHR-dependent skin barrier repair in atopic dermatitis. J Clin Invest (2013) 1.23
Transcriptional response of bronchial epithelial cells to Pseudomonas aeruginosa: identification of early mediators of host defense. Physiol Genomics (2005) 1.23
Microbiome dynamics of human epidermis following skin barrier disruption. Genome Biol (2012) 1.15
Joint hypermobility syndromes: the pathophysiologic role of tenascin-X gene defects. Arthritis Rheum (2004) 1.13
Cystatin M/E is a high affinity inhibitor of cathepsin V and cathepsin L by a reactive site that is distinct from the legumain-binding site. A novel clue for the role of cystatin M/E in epidermal cornification. J Biol Chem (2006) 1.10
Development and validation of human psoriatic skin equivalents. Am J Pathol (2008) 1.09
Psoriasis risk genes of the late cornified envelope-3 group are distinctly expressed compared with genes of other LCE groups. Am J Pathol (2011) 1.07
Beta-defensin-2 protein is a serum biomarker for disease activity in psoriasis and reaches biologically relevant concentrations in lesional skin. PLoS One (2009) 1.06
Accuracy and differential bias in copy number measurement of CCL3L1 in association studies with three auto-immune disorders. BMC Genomics (2011) 1.06
Attenuation of melanoma invasion by a secreted variant of activated leukocyte cell adhesion molecule. Cancer Res (2008) 1.03
Human single-chain antibodies reactive with native chondroitin sulfate detect chondroitin sulfate alterations in melanoma and psoriasis. J Invest Dermatol (2004) 1.03
Association of β-defensin copy number and psoriasis in three cohorts of European origin. J Invest Dermatol (2012) 1.02
A novel translation re-initiation mechanism for the p63 gene revealed by amino-terminal truncating mutations in Rapp-Hodgkin/Hay-Wells-like syndromes. Hum Mol Genet (2008) 1.02
Skin microbiome imbalance in patients with STAT1/STAT3 defects impairs innate host defense responses. J Innate Immun (2013) 1.02
Wound healing in tenascin-X deficient mice suggests that tenascin-X is involved in matrix maturation rather than matrix deposition. Connect Tissue Res (2007) 0.98
A comprehensive analysis of pattern recognition receptors in normal and inflamed human epidermis: upregulation of dectin-1 in psoriasis. J Invest Dermatol (2010) 0.97
Microbiome and skin diseases. Curr Opin Allergy Clin Immunol (2013) 0.97
A null mutation in the cystatin M/E gene of ichq mice causes juvenile lethality and defects in epidermal cornification. Hum Mol Genet (2002) 0.97
Interactions of human tenascin-X domains with dermal extracellular matrix molecules. Arch Dermatol Res (2006) 0.96
A proteomics platform combining depletion, multi-lectin affinity chromatography (M-LAC), and isoelectric focusing to study the breast cancer proteome. Anal Chem (2011) 0.96
Rho kinase inhibitor Y-27632 prolongs the life span of adult human keratinocytes, enhances skin equivalent development, and facilitates lentiviral transduction. Tissue Eng Part A (2012) 0.96
Differential gene expression in premalignant human epidermis revealed by cluster analysis of serial analysis of gene expression (SAGE) libraries. FASEB J (2001) 0.95
Deletion of Late Cornified Envelope 3B and 3C genes is not associated with atopic dermatitis. J Invest Dermatol (2010) 0.94
Tumor necrosis factor related apoptosis inducing ligand triggers apoptosis in dividing but not in differentiating human epidermal keratinocytes. J Invest Dermatol (2003) 0.93
Predictors of long-term mortality in patients with cirrhosis of the liver admitted to a medical ICU. Chest (2004) 0.93
Hypertrophic scar formation is associated with an increased number of epidermal Langerhans cells. J Pathol (2004) 0.92
Type 2 helper T-cell cytokines induce morphologic and molecular characteristics of atopic dermatitis in human skin equivalent. Am J Pathol (2011) 0.92
A partial transcriptome of human epidermis. Genomics (2002) 0.90
Host defense effector molecules in mucosal secretions. FEMS Immunol Med Microbiol (2005) 0.90
Discovery of small molecule vanin inhibitors: new tools to study metabolism and disease. ACS Chem Biol (2013) 0.90
Drosomycin-like defensin, a human homologue of Drosophila melanogaster drosomycin with antifungal activity. Antimicrob Agents Chemother (2008) 0.89
Immunohistochemical expression of SKALP/elafin in squamous cell carcinoma of human lung. Oncol Rep (2002) 0.89
Strong induction of AIM2 expression in human epidermis in acute and chronic inflammatory skin conditions. Exp Dermatol (2012) 0.89
Sustained efficacy of the monoclonal anti-interleukin-1 beta antibody canakinumab in a 9-month trial in Schnitzler's syndrome. Ann Rheum Dis (2012) 0.88
Expression of the vanin gene family in normal and inflamed human skin: induction by proinflammatory cytokines. J Invest Dermatol (2009) 0.88
The biology of cystatin M/E and its cognate target proteases. J Invest Dermatol (2009) 0.88
Genetically programmed differences in epidermal host defense between psoriasis and atopic dermatitis patients. PLoS One (2008) 0.87
Genetics of psoriasis: evidence for epistatic interaction between skin barrier abnormalities and immune deviation. J Invest Dermatol (2012) 0.87
Colocalization of cystatin M/E and cathepsin V in lamellar granules and corneodesmosomes suggests a functional role in epidermal differentiation. J Invest Dermatol (2006) 0.87
Phenotypical and functional differences in germinative subpopulations derived from normal and psoriatic epidermis. J Invest Dermatol (2005) 0.86
Effect of daily stressors on psoriasis: a prospective study. J Invest Dermatol (2009) 0.86
Transcriptional regulation of the elafin gene in human keratinocytes. J Invest Dermatol (2003) 0.86
APR-246/PRIMA-1(MET) rescues epidermal differentiation in skin keratinocytes derived from EEC syndrome patients with p63 mutations. Proc Natl Acad Sci U S A (2013) 0.86
Evidence that unrestricted legumain activity is involved in disturbed epidermal cornification in cystatin M/E deficient mice. Hum Mol Genet (2004) 0.86
The cystatin M/E-cathepsin L balance is essential for tissue homeostasis in epidermis, hair follicles, and cornea. FASEB J (2010) 0.85
Colocalization of cystatin M/E and its target proteases suggests a role in terminal differentiation of human hair follicle and nail. J Invest Dermatol (2008) 0.84
Comparison of antiproliferative effects of experimental and established antipsoriatic drugs on human keratinocytes, using a simple 96-well-plate assay. In Vitro Cell Dev Biol Anim (2003) 0.83
Increased expression of carbonic anhydrase II (CA II) in lesional skin of atopic dermatitis: regulation by Th2 cytokines. J Invest Dermatol (2007) 0.83
Successful canakinumab treatment identifies IL-1β as a pivotal mediator in Schnitzler syndrome. J Allergy Clin Immunol (2011) 0.82
Keratinocytes drive melanoma invasion in a reconstructed skin model. Melanoma Res (2010) 0.81
An overview of methods for the in vivo evaluation of tissue-engineered skin constructs. Tissue Eng Part B Rev (2010) 0.81
The effect of industry support on participants' perceptions of bias in continuing medical education. Acad Med (2010) 0.81
An in vitro wound healing model for evaluation of dermal substitutes. Wound Repair Regen (2013) 0.80
Efficacy and safety of tanezumab in the treatment of pain from bone metastases. Pain (2015) 0.79
The human cystatin M/E gene (CST6): exclusion candidate gene for harlequin ichthyosis. J Invest Dermatol (2003) 0.79
Combination of pantothenamides with vanin inhibitors as a novel antibiotic strategy against gram-positive bacteria. Antimicrob Agents Chemother (2013) 0.78
Co-culture of healthy human keratinocytes and T-cells promotes keratinocyte chemokine production and RORγt-positive IL-17 producing T-cell populations. J Dermatol Sci (2012) 0.78
Well-defined clinical presentation of Ehlers-Danlos syndrome in patients with tenascin-X deficiency: a report of four cases. Clin Dysmorphol (2012) 0.78
A simple technique for high-throughput screening of drugs that modulate normal and psoriasis-like differentiation in cultured human keratinocytes. Skin Pharmacol Appl Skin Physiol (2002) 0.78
Identification of avarol derivatives as potential antipsoriatic drugs using an in vitro model for keratinocyte growth and differentiation. Life Sci (2006) 0.78
Transcriptomics and proteomics of human skin. Brief Funct Genomic Proteomic (2003) 0.78
Pattern recognition receptors in infectious skin diseases. Microbes Infect (2012) 0.78
Epidermal expression of host response genes upon skin barrier disruption in normal skin and uninvolved skin of psoriasis and atopic dermatitis patients. J Invest Dermatol (2010) 0.77
Analysis of obstetric complications and uterine connective tissue in tenascin-X-deficient humans and mice. Cell Tissue Res (2008) 0.77
A thioesterase bypasses the requirement for exogenous fatty acids in the plsX deletion of Streptococcus pneumoniae. Mol Microbiol (2015) 0.77
Pattern recognition receptors in immune disorders affecting the skin. J Innate Immun (2012) 0.77
Genotype-phenotype correlations in a prospective cohort study of paediatric plaque psoriasis: lack of correlation between HLA-C*06 and family history of psoriasis. Acta Derm Venereol (2014) 0.76
Pharmacological Inhibition of Vanin Activity Attenuates Transplant Vasculopathy in Rat Aortic Allografts. Transplantation (2016) 0.76
Extraction and structural analysis of glycosaminoglycans from formalin-fixed, paraffin-embedded tissues. Glycobiology (2012) 0.76
Abdominal aortic aneurysm is associated with high serum levels of tenascin-X and decreased aneurysmal tissue tenascin-X. Circulation (2006) 0.76
A replication study of the association between rheumatoid arthritis and deletion of the late cornified envelope genes LCE3B and LCE3C. PLoS One (2012) 0.76
Cystatin M/E knockdown by lentiviral delivery of shRNA impairs epidermal morphogenesis of human skin equivalents. Exp Dermatol (2012) 0.76
Construction of a microstructured collagen membrane mimicking the papillary dermis architecture and guiding keratinocyte morphology and gene expression. Macromol Biosci (2012) 0.76
A molecular signature of epithelial host defense: comparative gene expression analysis of cultured bronchial epithelial cells and keratinocytes. BMC Genomics (2006) 0.76
Transplantation of reconstructed human skin on nude mice: a model system to study expression of human tenascin-X and elastic fiber components. Cell Tissue Res (2004) 0.75
Functional characterization of beta1-integrin-positive epidermal cell populations. Acta Derm Venereol (2004) 0.75
Hepatitis B: a strategy for evaluation and management. Cleve Clin J Med (2009) 0.75
Serial analysis of gene expression in human keratinocytes and epidermis. Methods Mol Biol (2005) 0.75
Analysis of protein-protein interaction between late cornified envelope proteins and corneodesmosin. Exp Dermatol (2014) 0.75
Development of a keratinocyte-based screening model for antipsoriatic drugs using green fluorescent protein under the control of an endogenous promoter. J Biomol Screen (2002) 0.75