Published in J Neurotrauma on August 03, 2012
Animal models of traumatic brain injury. Nat Rev Neurosci (2013) 2.75
Young APOE4 targeted replacement mice exhibit poor spatial learning and memory, with reduced dendritic spine density in the medial entorhinal cortex. Learn Mem (2013) 0.95
Cognitive, affective, and conative theory of mind (ToM) in children with traumatic brain injury. Dev Cogn Neurosci (2012) 0.94
Changes in mouse cognition and hippocampal gene expression observed in a mild physical- and blast-traumatic brain injury. Neurobiol Dis (2013) 0.90
Found in translation: Understanding the biology and behavior of experimental traumatic brain injury. Neurosci Biobehav Rev (2014) 0.89
Mouse models of intracerebral hemorrhage in ventricle, cortex, and hippocampus by injections of autologous blood or collagenase. PLoS One (2014) 0.88
Experimental traumatic brain injury induces rapid aggregation and oligomerization of amyloid-beta in an Alzheimer's disease mouse model. J Neurotrauma (2013) 0.88
Temporal patterns of cortical proliferation of glial cell populations after traumatic brain injury in mice. ASN Neuro (2014) 0.87
Traumatic brain injury - modeling neuropsychiatric symptoms in rodents. Front Neurol (2013) 0.86
Exendin-4 ameliorates traumatic brain injury-induced cognitive impairment in rats. PLoS One (2013) 0.85
Essential roles of neutral ceramidase and sphingosine in mitochondrial dysfunction due to traumatic brain injury. J Biol Chem (2014) 0.85
Controlled cortical impact results in an extensive loss of dendritic spines that is not mediated by injury-induced amyloid-beta accumulation. J Neurotrauma (2013) 0.84
Time-dependent effects of CX3CR1 in a mouse model of mild traumatic brain injury. J Neuroinflammation (2015) 0.83
Repetitive grooming and sensorimotor abnormalities in an ephrin-A knockout model for Autism Spectrum Disorders. Behav Brain Res (2014) 0.82
Performance of Male and Female C57BL/6J Mice on Motor and Cognitive Tasks Commonly Used in Pre-Clinical Traumatic Brain Injury Research. J Neurotrauma (2015) 0.81
Long-lasting suppression of acoustic startle response after mild traumatic brain injury. J Neurotrauma (2015) 0.80
Primary blast causes mild, moderate, severe and lethal TBI with increasing blast overpressures: Experimental rat injury model. Sci Rep (2016) 0.80
Dendritic Spine Loss and Chronic White Matter Inflammation in a Mouse Model of Highly Repetitive Head Trauma. Am J Pathol (2016) 0.80
The Controlled Cortical Impact Model: Applications, Considerations for Researchers, and Future Directions. Front Neurol (2016) 0.80
A Novel Closed-Head Model of Mild Traumatic Brain Injury Using Focal Primary Overpressure Blast to the Cranium in Mice. J Neurotrauma (2015) 0.79
Imatinib treatment reduces brain injury in a murine model of traumatic brain injury. Front Cell Neurosci (2015) 0.79
Cortical contusion injury disrupts olfactory bulb neurogenesis in adult mice. BMC Neurosci (2013) 0.79
Mental Health Implications of Traumatic Brain Injury (TBI) in Children and Youth. J Can Acad Child Adolesc Psychiatry (2015) 0.78
Traumatic Brain Injury Leads to Development of Parkinson's Disease Related Pathology in Mice. Front Neurosci (2016) 0.77
Controlled cortical impact before or after fear conditioning does not affect fear extinction in mice. Brain Res (2015) 0.77
Behavioral Outcomes Differ between Rotational Acceleration and Blast Mechanisms of Mild Traumatic Brain Injury. Front Neurol (2016) 0.77
Neuropsychiatric Symptom Modeling in Male and Female C57BL/6J Mice after Experimental Traumatic Brain Injury. J Neurotrauma (2016) 0.77
Gene co-expression networks identify Trem2 and Tyrobp as major hubs in human APOE expressing mice following traumatic brain injury. Neurobiol Dis (2017) 0.76
Considerations for Experimental Animal Models of Concussion, Traumatic Brain Injury, and Chronic Traumatic Encephalopathy-These Matters Matter. Front Neurol (2017) 0.76
Automated monitoring of early neurobehavioral changes in mice following traumatic brain injury. Neural Regen Res (2016) 0.76
Deficits in discrimination after experimental frontal brain injury are mediated by motivation and can be improved by nicotinamide administration. J Neurotrauma (2014) 0.76
Animal models to improve our understanding and treatment of suicidal behavior. Transl Psychiatry (2017) 0.76
Genetic Deletion of the Clathrin Adaptor GGA3 Reduces Anxiety and Alters GABAergic Transmission. PLoS One (2016) 0.75
Elucidating the severity of preclinical traumatic brain injury models: a role for functional assessment? Neurosurgery (2014) 0.75
Overview of Traumatic Brain Injury: An Immunological Context. Brain Sci (2017) 0.75
Sexual dimorphism in the inflammatory response to traumatic brain injury. Glia (2017) 0.75
Thrombospondin-1 Gene Deficiency Worsens the Neurological Outcomes of Traumatic Brain Injury in Mice. Int J Med Sci (2017) 0.75
Neuroinflammation, myelin and behavior: Temporal patterns following mild traumatic brain injury in mice. PLoS One (2017) 0.75
Temporal Changes in Cortical and Hippocampal Expression of Genes Important for Brain Glucose Metabolism Following Controlled Cortical Impact Injury in Mice. Front Endocrinol (Lausanne) (2017) 0.75
Mini Review of Controlled Cortical Impact: A Well-Suited Device for Concussion Research. Brain Sci (2017) 0.75
Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Methods (1985) 9.05
The use of the elevated plus maze as an assay of anxiety-related behavior in rodents. Nat Protoc (2007) 4.51
Rates of major depressive disorder and clinical outcomes following traumatic brain injury. JAMA (2010) 2.57
Cognitive deficits following traumatic brain injury produced by controlled cortical impact. J Neurotrauma (1992) 2.01
Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury. Nat Med (2009) 1.95
Elevated body swing test: a new behavioral parameter for rats with 6-hydroxydopamine-induced hemiparkinsonism. J Neurosci (1995) 1.88
Major depression following traumatic brain injury. Arch Gen Psychiatry (2004) 1.88
The neurobehavioural rating scale: assessment of the behavioural sequelae of head injury by the clinician. J Neurol Neurosurg Psychiatry (1987) 1.79
Morris water maze deficits in rats following traumatic brain injury: lateral controlled cortical impact. J Neurotrauma (1997) 1.53
Evaluation of memory dysfunction following experimental brain injury using the Morris water maze. J Neurotrauma (1991) 1.46
Mild traumatic brain injury induces persistent cognitive deficits and behavioral disturbances in mice. J Neurotrauma (2005) 1.23
Model development and behavioral assessment of focal cerebral ischemia in rats. Life Sci (1999) 1.15
Effects of neonatal antiepileptic drug exposure on cognitive, emotional, and motor function in adult rats. J Pharmacol Exp Ther (2011) 1.14
Role of glycogen synthase kinase-3beta in early depressive behavior induced by mild traumatic brain injury. Mol Cell Neurosci (2006) 1.12
Experimental traumatic brain injury induces a pervasive hyperanxious phenotype in rats. J Neurotrauma (2008) 1.04
The GABA(A) receptor agonist THIP ameliorates specific behavioral deficits in the mouse model of fragile X syndrome. Dev Neurosci (2011) 1.04
Neonatal exposure to phenobarbital potentiates schizophrenia-like behavioral outcomes in the rat. Neuropharmacology (2012) 1.04
The role of injury severity in neurobehavioral outcome 3 months after traumatic brain injury. Neuropsychiatry Neuropsychol Behav Neurol (2002) 1.01
Temporal profile of apoptotic-like changes in neurons and astrocytes following controlled cortical impact injury in the rat. Exp Neurol (1999) 1.01
Effects of traumatic brain injury of different severities on emotional, cognitive, and oxidative stress-related parameters in mice. J Neurotrauma (2010) 1.00
Attention and memory dysfunction after traumatic brain injury: cholinergic mechanisms, sensory gating, and a hypothesis for further investigation. Brain Inj (1999) 0.97
Progressive metabolic and structural cerebral perturbations after traumatic brain injury: an in vivo imaging study in the rat. J Nucl Med (2010) 0.96
Depression-like and anxiety-like behavioural aftermaths of impact accelerated traumatic brain injury in rats: a model of comorbid depression and anxiety? Behav Brain Res (2009) 0.96
Neuropsychological, psychosocial and vocational correlates of the Glasgow Outcome Scale at 6 months post-injury: a study of moderate to severe traumatic brain injury patients. Brain Inj (1998) 0.94
Behavioral responses of C57BL/6, FVB/N, and 129/SvEMS mouse strains to traumatic brain injury: implications for gene targeting approaches to neurotrauma. J Neurotrauma (1999) 0.94
Behavioral consequences of minimal traumatic brain injury in mice. Acta Neurobiol Exp (Wars) (2011) 0.92
Teratogenic effects of maternal antidepressant exposure on neural substrates of drug-seeking behavior in offspring. Addict Biol (2007) 0.90
Long-term outcome following traumatic brain injury: a comparison of subjective reports by those injured and their relatives. Neuropsychol Rehabil (2009) 0.90
The nature, frequency and course of psychiatric disorders in the first year after traumatic brain injury: a prospective study. Psychol Med (2011) 0.89
Nitric oxide synthase inhibitors augment the effects of serotonin re-uptake inhibitors in the forced swimming test. Eur Neuropsychopharmacol (2004) 0.89
Injury severity and sensitivity to treatment after controlled cortical impact in rats. J Neurotrauma (2001) 0.87
DHEAS repeated treatment improves cognitive and behavioral deficits after mild traumatic brain injury. Eur Neuropsychopharmacol (2007) 0.87
Neuroanatomical correlation of behavioral deficits in the CCI model of TBI. J Neurosci Methods (2010) 0.86
Mild traumatic lesion of the right parietal cortex of the rat: selective behavioural deficits in the absence of neurological impairment. Behav Brain Res (1998) 0.86
Ventral pallidum mediates amygdala-evoked deficits in prepulse inhibition. Behav Neurosci (2012) 0.86
Comparison of subjective cognitive complaints with neuropsychological tests in individuals with mild vs more severe traumatic brain injuries. Brain Inj (2012) 0.85
Impaired auditory gating and P50 nonsuppression following traumatic brain injury. J Neuropsychiatry Clin Neurosci (2000) 0.84
Reduced sensorimotor reactivity following traumatic brain injury in rats. Brain Res (1996) 0.81
In vivo assessment of brain interstitial fluid with microdialysis reveals plaque-associated changes in amyloid-beta metabolism and half-life. J Neurosci (2003) 5.00
ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo. Neuron (2004) 4.21
P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model. J Clin Invest (2005) 2.81
Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A (2002) 2.58
ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE. J Biol Chem (2004) 2.19
Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model. J Neurosci (2005) 2.17
Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease. J Neurochem (2002) 2.13
Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance. Neuron (2009) 2.03
Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease. J Clin Invest (2008) 2.01
Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury. Nat Med (2009) 1.95
Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease. J Biol Chem (2005) 1.91
Electromagnetic controlled cortical impact device for precise, graded experimental traumatic brain injury. J Neurotrauma (2007) 1.79
Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease. Neurobiol Dis (2002) 1.74
Pomegranate juice decreases amyloid load and improves behavior in a mouse model of Alzheimer's disease. Neurobiol Dis (2006) 1.67
The low density lipoprotein receptor regulates the level of central nervous system human and murine apolipoprotein E but does not modify amyloid plaque pathology in PDAPP mice. J Biol Chem (2005) 1.63
Apolipoprotein E markedly facilitates age-dependent cerebral amyloid angiopathy and spontaneous hemorrhage in amyloid precursor protein transgenic mice. J Neurosci (2003) 1.58
Topography of dyskinesias and torticollis evoked by inhibition of substantia nigra pars reticulata. Mov Disord (2012) 1.57
Rapid microglial response around amyloid pathology after systemic anti-Abeta antibody administration in PDAPP mice. J Neurosci (2008) 1.43
Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states. Neurobiol Aging (2012) 1.41
The pathobiology of moderate diffuse traumatic brain injury as identified using a new experimental model of injury in rats. Neurobiol Dis (2004) 1.21
Human immunodeficiency virus type 1 alters brain-derived neurotrophic factor processing in neurons. J Neurosci (2012) 1.11
The metalloprotease inhibitor TIMP-3 regulates amyloid precursor protein and apolipoprotein E receptor proteolysis. J Neurosci (2007) 1.09
Low-density lipoprotein receptors regulate microglial inflammation through c-Jun N-terminal kinase. Glia (2009) 1.04
The GABA(A) receptor agonist THIP ameliorates specific behavioral deficits in the mouse model of fragile X syndrome. Dev Neurosci (2011) 1.04
Fluid-percussion-induced traumatic brain injury model in rats. Nat Protoc (2010) 1.00
ApoAI deficiency results in marked reductions in plasma cholesterol but no alterations in amyloid-beta pathology in a mouse model of Alzheimer's disease-like cerebral amyloidosis. Am J Pathol (2004) 0.98
Modulation of ABCA1 by an LXR agonist reduces β-amyloid levels and improves outcome after traumatic brain injury. J Neurotrauma (2011) 0.98
Drugs, the brain, and behavior: a graduate student-run comprehensive course in neuroscience. J Undergrad Neurosci Educ (2012) 0.97
Young APOE4 targeted replacement mice exhibit poor spatial learning and memory, with reduced dendritic spine density in the medial entorhinal cortex. Learn Mem (2013) 0.95
Transient inactivation of basolateral amygdala during selective satiation disrupts reinforcer devaluation in rats. Behav Neurosci (2012) 0.91
Nitric oxide synthase inhibitors augment the effects of serotonin re-uptake inhibitors in the forced swimming test. Eur Neuropsychopharmacol (2004) 0.89
Defense-like behaviors evoked by pharmacological disinhibition of the superior colliculus in the primate. J Neurosci (2013) 0.89
Superior colliculus mediates cervical dystonia evoked by inhibition of the substantia nigra pars reticulata. J Neurosci (2012) 0.89
Experimental traumatic brain injury induces rapid aggregation and oligomerization of amyloid-beta in an Alzheimer's disease mouse model. J Neurotrauma (2013) 0.88
The cytoplasmic adaptor protein X11alpha and extracellular matrix protein Reelin regulate ApoE receptor 2 trafficking and cell movement. FASEB J (2009) 0.88
Measurement of apolipoprotein E and amyloid β clearance rates in the mouse brain using bolus stable isotope labeling. Mol Neurodegener (2012) 0.88
In vivo human apolipoprotein E isoform fractional turnover rates in the CNS. PLoS One (2012) 0.86
24S-hydroxycholesterol effects on lipid metabolism genes are modeled in traumatic brain injury. Brain Res (2010) 0.85
Cholesterol independent effect of LXR agonist TO-901317 on gamma-secretase. J Neurochem (2007) 0.85
Neurotrophins modulate the expression of chemokine receptors in the brain. J Neurovirol (2010) 0.84
Controlled cortical impact results in an extensive loss of dendritic spines that is not mediated by injury-induced amyloid-beta accumulation. J Neurotrauma (2013) 0.84
Regulation of central nervous system cholesterol homeostasis by the liver X receptor agonist TO-901317. Neurosci Lett (2007) 0.83
A visual, position-independent instrumental reinforcer devaluation task for rats. J Neurosci Methods (2010) 0.81
Differential effects of serotonin-specific and excitotoxic lesions of OFC on conditioned reinforcer devaluation and extinction in rats. Behav Brain Res (2013) 0.81
Chronic sazetidine-A maintains anxiolytic effects and slower weight gain following chronic nicotine without maintaining increased density of nicotinic receptors in rodent brain. J Neurochem (2014) 0.80
Cortical injury increases cholesterol 24S hydroxylase (Cyp46) levels in the rat brain. J Neurotrauma (2008) 0.80
It's money! Real-world grant experience through a student-run, peer-reviewed program. CBE Life Sci Educ (2013) 0.80
Are there really "epileptogenic" mechanisms or only corruptions of "normal" plasticity? Adv Exp Med Biol (2014) 0.77
Brain on steroids resists neurodegeneration. Nat Med (2004) 0.76
Challenges in neurodegeneration research. Front Psychiatry (2010) 0.75
Reduced cortical excitatory synapse number in APOE4 mice is associated with increased calcineurin activity. Neuroreport (2017) 0.75