PubRank

Oliver Schwardt

Author PubWeight™ 20.77‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 FimH antagonists for the oral treatment of urinary tract infections: from design and synthesis to in vitro and in vivo evaluation. J Med Chem 2010 1.14
2 Antiadhesion therapy for urinary tract infections--a balanced PK/PD profile proved to be key for success. J Med Chem 2012 0.95
3 Synthesis of sialic acid derivatives as ligands for the myelin-associated glycoprotein (MAG). Bioorg Med Chem 2007 0.93
4 From a library of MAG antagonists to nanomolar CD22 ligands. ChemMedChem 2011 0.92
5 Trivalent, Gal/GalNAc-containing ligands designed for the asialoglycoprotein receptor. Bioorg Med Chem 2008 0.87
6 Consistent bioactive conformation of the Neu5Acalpha(2-->3)Gal epitope upon lectin binding. Chembiochem 2008 0.87
7 Pre-organization of the core structure of E-selectin antagonists. Chemistry 2011 0.85
8 Low molecular weight antagonists of the myelin-associated glycoprotein: synthesis, docking, and biological evaluation. J Med Chem 2010 0.85
9 FimH antagonists: bioisosteres to improve the in vitro and in vivo PK/PD profile. J Med Chem 2015 0.85
10 Nanomolar E-selectin antagonists with prolonged half-lives by a fragment-based approach. J Am Chem Soc 2013 0.83
11 Design, synthesis and evaluation of monovalent ligands for the asialoglycoprotein receptor (ASGP-R). Bioorg Med Chem 2009 0.82
12 Target Selectivity of FimH Antagonists. J Med Chem 2012 0.81
13 A fragment-based in situ combinatorial approach to identify high-affinity ligands for unknown binding sites. Angew Chem Int Ed Engl 2010 0.81
14 FimH antagonists: structure-activity and structure-property relationships for biphenyl α-D-mannopyranosides. ChemMedChem 2012 0.81
15 Expression of the carbohydrate recognition domain of FimH and development of a competitive binding assay. Anal Biochem 2010 0.80
16 From the ganglioside GQ1balpha to glycomimetic antagonists of the myelin-associated glycoprotein (MAG). Chimia (Aarau) 2010 0.79
17 Antagonists of the myelin-associated glycoprotein: a new class of tetrasaccharide mimics. Bioorg Med Chem 2006 0.79
18 Binding epitopes of gangliosides to their neuronal receptor, myelin-associated glycoprotein, from saturation transfer difference NMR. Chembiochem 2008 0.79
19 Mimetics of the tri- and tetrasaccharide epitope of GQ1balpha as myelin-associated glycoprotein (MAG) ligands. Bioorg Med Chem 2007 0.78
20 A flow cytometry-based assay for screening FimH antagonists. Assay Drug Dev Technol 2011 0.78
21 Kinetic properties of carbohydrate-lectin interactions: FimH antagonists. ChemMedChem 2013 0.77
22 Kinetic and thermodynamic properties of MAG antagonists. Carbohydr Res 2010 0.77
23 Probing the carbohydrate recognition domain of E-selectin: the importance of the acid orientation in sLex mimetics. Bioorg Med Chem 2009 0.77
24 Development of an aggregation assay to screen FimH antagonists. J Microbiol Methods 2010 0.77
25 Is adamantane a suitable substituent to pre-organize the acid orientation in E-selectin antagonists? Bioorg Med Chem 2007 0.75
26 Synthesis of aryl sialosides using Mitsunobu conditions. Carbohydr Res 2004 0.75