Published in Traffic on June 20, 2012
Something old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulation. Cell Mol Life Sci (2013) 1.08
Activation of the cAMP/PKA pathway induces UT-A1 urea transporter monoubiquitination and targets it for lysosomal degradation. Am J Physiol Renal Physiol (2013) 0.82
Absent and abundant MET immunoreactivity is associated with poor prognosis of patients with oral and oropharyngeal squamous cell carcinoma. Oncotarget (2016) 0.78
Palmitoylation regulates the intracellular trafficking and stability of c-Met. Oncotarget (2016) 0.77
Necrosis- and apoptosis-related Met cleavages have divergent functional consequences. Cell Death Dis (2015) 0.77
Nuclear phosphorylated Y142 β-catenin accumulates in astrocytomas and glioblastomas and regulates cell invasion. Cell Cycle (2015) 0.77
MET receptor variant R970C favors calpain-dependent generation of a fragment promoting epithelial cell scattering. Oncotarget (2017) 0.75
c-Met expression and activity in urogenital cancers - novel aspects of signal transduction and medical implications. Cell Commun Signal (2017) 0.75
Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing. Nat Genet (2008) 43.63
A comprehensive catalogue of somatic mutations from a human cancer genome. Nature (2009) 24.27
A small-cell lung cancer genome with complex signatures of tobacco exposure. Nature (2009) 18.39
Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell (2011) 16.72
Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes. Nature (2010) 14.50
Complex landscapes of somatic rearrangement in human breast cancer genomes. Nature (2009) 13.45
The patterns and dynamics of genomic instability in metastatic pancreatic cancer. Nature (2010) 12.43
Mutational processes molding the genomes of 21 breast cancers. Cell (2012) 11.22
The life history of 21 breast cancers. Cell (2012) 10.59
Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer. Nat Genet (2009) 10.21
Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene. Cancer Cell (2003) 6.59
Drug development of MET inhibitors: targeting oncogene addiction and expedience. Nat Rev Drug Discov (2008) 4.76
The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met. Nature (2002) 2.99
Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer. Cancer Discov (2013) 2.87
Cell motility is controlled by SF2/ASF through alternative splicing of the Ron protooncogene. Mol Cell (2005) 2.85
Negative receptor signalling. Curr Opin Cell Biol (2003) 2.68
Concurrent fast and slow cycling of a transcriptional activator at an endogenous promoter. Science (2008) 2.08
Cancer therapy: can the challenge be MET? Trends Mol Med (2005) 1.81
MicroRNAs impair MET-mediated invasive growth. Cancer Res (2008) 1.81
MINT and IntAct contribute to the Second BioCreative challenge: serving the text-mining community with high quality molecular interaction data. Genome Biol (2008) 1.76
Tumorigenic and metastatic activity of human thyroid cancer stem cells. Cancer Res (2010) 1.73
Sema4D induces angiogenesis through Met recruitment by Plexin B1. Blood (2005) 1.65
Yes-associated protein regulation of adaptive liver enlargement and hepatocellular carcinoma development in mice. Hepatology (2011) 1.61
The Ets transcription factors of the PEA3 group: transcriptional regulators in metastasis. Biochim Biophys Acta (2006) 1.60
Molecular mechanisms of acquired resistance to tyrosine kinase targeted therapy. Mol Cancer (2010) 1.56
Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages. J Exp Med (2008) 1.53
Hepatocyte growth factor/scatter factor activates the ETS1 transcription factor by a RAS-RAF-MEK-ERK signaling pathway. Oncogene (2002) 1.53
MET and KRAS gene amplification mediates acquired resistance to MET tyrosine kinase inhibitors. Cancer Res (2010) 1.51
Ab-induced ectodomain shedding mediates hepatocyte growth factor receptor down-regulation and hampers biological activity. Proc Natl Acad Sci U S A (2006) 1.47
Enhanced c-Met activity promotes G-CSF-induced mobilization of hematopoietic progenitor cells via ROS signaling. Blood (2010) 1.44
Interplay between scatter factor receptors and B plexins controls invasive growth. Oncogene (2004) 1.43
Association of Fyn and Lyn with the proline-rich domain of glycoprotein VI regulates intracellular signaling. J Biol Chem (2002) 1.39
Plexin-B3 is a functional receptor for semaphorin 5A. EMBO Rep (2004) 1.39
Hepatocyte growth factor and its receptor are required for malaria infection. Nat Med (2003) 1.37
HGF/MET signalling protects Plasmodium-infected host cells from apoptosis. Cell Microbiol (2005) 1.28
CD100/Plexin-B1 interactions sustain proliferation and survival of normal and leukemic CD5+ B lymphocytes. Blood (2002) 1.27
Involvement of Rel/nuclear factor-kappaB transcription factors in keratinocyte senescence. Cancer Res (2004) 1.24
Conservation of epidermal growth factor receptor function in the human parasitic helminth Schistosoma mansoni. J Biol Chem (2004) 1.23
Molecular cancer therapy: can our expectation be MET? Eur J Cancer (2008) 1.19
Lysophospholipids stimulate prostate cancer cell migration via TRPV2 channel activation. Biochim Biophys Acta (2009) 1.19
HIF-1α stabilization by mitochondrial ROS promotes Met-dependent invasive growth and vasculogenic mimicry in melanoma cells. Free Radic Biol Med (2011) 1.17
Reactive oxygen species mediate Met receptor transactivation by G protein-coupled receptors and the epidermal growth factor receptor in human carcinoma cells. J Biol Chem (2004) 1.16
Activation of HER family members in gastric carcinoma cells mediates resistance to MET inhibition. Mol Cancer (2010) 1.14
Senescence-associated oxidative DNA damage promotes the generation of neoplastic cells. Cancer Res (2009) 1.11
Semaphorin 4D regulates gonadotropin hormone-releasing hormone-1 neuronal migration through PlexinB1-Met complex. J Cell Biol (2008) 1.09
MET overexpression turns human primary osteoblasts into osteosarcomas. Cancer Res (2006) 1.09
Role of cationic channel TRPV2 in promoting prostate cancer migration and progression to androgen resistance. Cancer Res (2010) 1.09
Proapoptotic function of the MET tyrosine kinase receptor through caspase cleavage. Mol Cell Biol (2004) 1.09
Cell-autonomous and non-cell-autonomous mechanisms of HGF/MET-driven resistance to targeted therapies: from basic research to a clinical perspective. Cancer Discov (2013) 1.09
Roles of stem cell factor/c-Kit and effects of Glivec/STI571 in human uveal melanoma cell tumorigenesis. J Biol Chem (2004) 1.08
MiR-1 downregulation cooperates with MACC1 in promoting MET overexpression in human colon cancer. Clin Cancer Res (2011) 1.07
Down-regulation of the met receptor tyrosine kinase by presenilin-dependent regulated intramembrane proteolysis. Mol Biol Cell (2009) 1.06
MicroRNA/gene profiling unveils early molecular changes and nuclear factor erythroid related factor 2 (NRF2) activation in a rat model recapitulating human hepatocellular carcinoma (HCC). Hepatology (2013) 1.05
TGFalpha expression impairs Trastuzumab-induced HER2 downregulation. Oncogene (2005) 1.03
Only a subset of Met-activated pathways are required to sustain oncogene addiction. Sci Signal (2009) 1.02
Smartphone-centred wearable sensors network for monitoring patients with bipolar disorder. Conf Proc IEEE Eng Med Biol Soc (2011) 1.02
Functional characterization of in vivo effector CD4(+) and CD8(+) T cell responses in acute Toxoplasmosis: an interplay of IFN-gamma and cytolytic T cells. Vaccine (2010) 0.99
HER2-positive breast cancer cells resistant to trastuzumab and lapatinib lose reliance upon HER2 and are sensitive to the multitargeted kinase inhibitor sorafenib. Breast Cancer Res Treat (2010) 0.95
Rapid purification of human ductal cells from human pancreatic fractions with surface antibody CA19-9. Biochem Biophys Res Commun (2004) 0.95
Sequential native peptide ligation strategies for total chemical protein synthesis. Chem Soc Rev (2012) 0.93
Delineation of the region in the glycoprotein VI tail required for association with the Fc receptor gamma-chain. J Biol Chem (2003) 0.93
Fmoc solid-phase synthesis of peptide thioesters using an intramolecularn,S-acyl shift. Org Lett (2005) 0.93
Bis(2-sulfanylethyl)amino native peptide ligation. Org Lett (2010) 0.92
Met degradation: more than one stone to shoot a receptor down. FASEB J (2012) 0.92
The venus kinase receptor (VKR) family: structure and evolution. BMC Genomics (2013) 0.91
MnSOD upregulation induces autophagic programmed cell death in senescent keratinocytes. PLoS One (2010) 0.91
Only a subset of Met-activated pathways are required to sustain oncogene addiction. Sci Signal (2009) 0.91
Targeting MET: why, where and how? Curr Opin Pharmacol (2013) 0.91
Growth factor receptors in helminth parasites: signalling and host-parasite relationships. FEBS Lett (2006) 0.91
Reduced tumorigenesis in mouse mammary cancer cells following inhibition of Pea3- or Erm-dependent transcription. J Cell Sci (2008) 0.90
Local hypothyroidism favors the progression of preneoplastic lesions to hepatocellular carcinoma in rats. Hepatology (2014) 0.89
Matrix-free laser desorption/ionization mass spectrometry on silicon nanowire arrays prepared by chemical etching of crystalline silicon. Langmuir (2010) 0.89
Loss of Hypermethylated in Cancer 1 (HIC1) in breast cancer cells contributes to stress-induced migration and invasion through β-2 adrenergic receptor (ADRB2) misregulation. J Biol Chem (2011) 0.89
The Fc receptor gamma-chain is necessary and sufficient to initiate signalling through glycoprotein VI in transfected cells by the snake C-type lectin, convulxin. Eur J Biochem (2002) 0.89
Interaction of calmodulin with the cytoplasmic domain of platelet glycoprotein VI. Blood (2002) 0.87
Presarcopenia and sarcopenia in hip-fracture women: prevalence and association with ability to function in activities of daily living. Aging Clin Exp Res (2015) 0.87
Anchorage of synthetic peptides onto liposomes via hydrazone and alpha-oxo hydrazone bonds. preliminary functional investigations. Bioconjug Chem (2005) 0.87
The ganglioside G(D2) induces the constitutive activation of c-Met in MDA-MB-231 breast cancer cells expressing the G(D3) synthase. Glycobiology (2012) 0.86
Caspase cleavage of the MET receptor generates an HGF interfering fragment. Biochem Biophys Res Commun (2008) 0.86
Expression of the c-kit receptor in choroidal melanomas. Melanoma Res (2003) 0.86
Methylation analysis of the promoter F of estrogen receptor alpha gene: effects on the level of transcription on human osteoblastic cells. J Steroid Biochem Mol Biol (2004) 0.86
Resistance to targeted therapies: a role for microRNAs? Trends Mol Med (2013) 0.85
The glucose transporter 2 undergoes plasma membrane endocytosis and lysosomal degradation in a secretagogue-dependent manner. Endocrinology (2009) 0.85
Identification of a novel endoplasmic reticulum stress response element regulated by XBP1. J Biol Chem (2013) 0.85
Cellular senescence involves an intracrine prostaglandin E2 pathway in human fibroblasts. Biochim Biophys Acta (2013) 0.85
Ets-1 controls breast cancer cell balance between invasion and growth. Int J Cancer (2014) 0.84
Senescent fibroblasts enhance early skin carcinogenic events via a paracrine MMP-PAR-1 axis. PLoS One (2013) 0.84
PASE: a web-based platform for peptide/protein microarray experiments. Methods Mol Biol (2009) 0.84
Gene expression changes in Schistosoma mansoni sporocysts induced by Biomphalaria glabrata embryonic cells. Parasitol Res (2002) 0.84