Published in J Biol Chem on May 15, 2004
Targeting of melanoma brain metastases using engineered neural stem/progenitor cells. Neuro Oncol (2006) 1.57
C-kit protein expression correlated with activating mutations in KIT gene in oral mucosal melanoma. Virchows Arch (2007) 1.26
Genetic and molecular characterization of uveal melanoma cell lines. Pigment Cell Melanoma Res (2012) 1.23
Correlation between KIT expression and KIT mutation in melanoma: a study of 173 cases with emphasis on the acral-lentiginous/mucosal type. Mod Pathol (2009) 1.21
The Role of B-RAF Mutations in Melanoma and the Induction of EMT via Dysregulation of the NF-κB/Snail/RKIP/PTEN Circuit. Genes Cancer (2010) 1.14
Impact of combined mTOR and MEK inhibition in uveal melanoma is driven by tumor genotype. PLoS One (2012) 1.03
Mda-9/syntenin is expressed in uveal melanoma and correlates with metastatic progression. PLoS One (2012) 1.01
The role of c-kit and imatinib mesylate in uveal melanoma. J Carcinog (2005) 0.91
Driver mutations in melanoma: lessons learned from bench-to-bedside studies. Curr Oncol Rep (2012) 0.89
KITLG is a novel target of miR-34c that is associated with the inhibition of growth and invasion in colorectal cancer cells. J Cell Mol Med (2014) 0.88
Kit and foxd3 genetically interact to regulate melanophore survival in zebrafish. Dev Dyn (2009) 0.87
O-Mel-Inib: a Cancéro-pôle Nord-Ouest multicenter phase II trial of high-dose imatinib mesylate in metastatic uveal melanoma. Invest New Drugs (2008) 0.84
Episodic Src activation in uveal melanoma revealed by kinase activity profiling. Br J Cancer (2009) 0.83
Serum-free cultivation of adult normal human choroidal melanocytes. Graefes Arch Clin Exp Ophthalmol (2007) 0.80
Expression of Sox10 and c-kit in sinonasal mucosal melanomas arising in the Chinese population. Head Neck Pathol (2012) 0.79
Therapeutic opportunities in noncutaneous melanoma. Ther Adv Med Oncol (2009) 0.78
Expression analysis of genes and pathways associated with liver metastases of the uveal melanoma. BMC Med Genet (2014) 0.76
Mechanisms of resistance to imatinib mesylate in KIT-positive metastatic uveal melanoma. Clin Exp Metastasis (2014) 0.75
PD-1-expressing tumor-infiltrating T cells are a favorable prognostic biomarker in HPV-associated head and neck cancer. Cancer Res (2012) 2.43
Beneficial effect of human anti-amyloid-beta active immunization on neurite morphology and tau pathology. Brain (2010) 2.33
Concurrent fast and slow cycling of a transcriptional activator at an endogenous promoter. Science (2008) 2.08
Parkin deficiency increases vulnerability to inflammation-related nigral degeneration. J Neurosci (2008) 1.85
Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT. PLoS One (2009) 1.55
Hepatocyte growth factor/scatter factor activates the ETS1 transcription factor by a RAS-RAF-MEK-ERK signaling pathway. Oncogene (2002) 1.53
The significance of cortical cerebellar microbleeds and microinfarcts in neurodegenerative and cerebrovascular diseases. A post-mortem 7.0-tesla magnetic resonance study with neuropathological correlates. Cerebrovasc Dis (2015) 1.53
Mutation of B-Raf in human choroidal melanoma cells mediates cell proliferation and transformation through the MEK/ERK pathway. J Biol Chem (2003) 1.33
The Escherichia coli RecQ helicase functions as a monomer. J Biol Chem (2003) 1.31
Neuroinflammation in Parkinson's disease. J Neuroimmune Pharmacol (2009) 1.20
Extracellular signal-regulated kinase-dependent proliferation is mediated through the protein kinase A/B-Raf pathway in human uveal melanoma cells. J Biol Chem (2006) 1.16
A new prognostic clinicopathological classification of pituitary adenomas: a multicentric case-control study of 410 patients with 8 years post-operative follow-up. Acta Neuropathol (2013) 1.15
Prevalence of small cerebral bleeds in patients with a neurodegenerative dementia: a neuropathological study. J Neurol Sci (2010) 1.13
Clinical outcome in 19 French and Spanish patients with valosin-containing protein myopathy associated with Paget's disease of bone and frontotemporal dementia. Neuromuscul Disord (2009) 1.12
Amyloid-beta(1-42) alters structure and function of retinal pigmented epithelial cells. Aging Cell (2009) 1.11
From tau phosphorylation to tau aggregation: what about neuronal death? Biochem Soc Trans (2010) 1.08
Fiber-type differences in masseter muscle associated with different facial morphologies. Am J Orthod Dentofacial Orthop (2005) 1.08
Identification and characterization of tumor antigens by using antibody phage display and intrabody strategies. Mol Immunol (2007) 1.07
Endocan in cancers: a lesson from a circulating dermatan sulfate proteoglycan. Int J Cell Biol (2013) 1.07
Sustained versus transient ERK1/2 signaling underlies the anti- and proapoptotic effects of oxidative stress in human RPE cells. Invest Ophthalmol Vis Sci (2006) 1.06
Absence of beta-amyloid deposits after immunization in Alzheimer disease with Lewy body dementia. Arch Neurol (2007) 1.04
Mechanism of HIV-1 integrase inhibition by styrylquinoline derivatives in vitro. Mol Pharmacol (2004) 1.03
Staging of sporadic Parkinson disease-related alpha-synuclein pathology: inter- and intra-rater reliability. J Neuropathol Exp Neurol (2005) 1.03
Tau aggregation in the hippocampal formation: an ageing or a pathological process? Exp Gerontol (2002) 1.03
Pin1 allows for differential Tau dephosphorylation in neuronal cells. Mol Cell Neurosci (2006) 1.02
Brain-specific change in alternative splicing of Tau exon 6 in myotonic dystrophy type 1. Biochim Biophys Acta (2005) 1.01
Deletion of the progranulin gene in patients with frontotemporal lobar degeneration or Parkinson disease. Neurobiol Dis (2008) 0.98
The PI3K/Akt and mTOR/P70S6K signaling pathways in human uveal melanoma cells: interaction with B-Raf/ERK. Invest Ophthalmol Vis Sci (2009) 0.97
The actin cytoskeleton-associated protein zyxin acts as a tumor suppressor in Ewing tumor cells. Exp Cell Res (2004) 0.97
Low HER2-expressing glioblastomas are more often secondary to anaplastic transformation of low-grade glioma. J Neurooncol (2007) 0.96
17-AAG and 17-DMAG-induced inhibition of cell proliferation through B-Raf downregulation in WT B-Raf-expressing uveal melanoma cell lines. Invest Ophthalmol Vis Sci (2008) 0.95
Stimulation of the primary anti-HIV antibody response by IFN-alpha in patients with acute HIV-1 infection. J Leukoc Biol (2008) 0.95
A novel mutation in the dynamin 2 gene in a Charcot-Marie-Tooth type 2 patient: clinical and pathological findings. Neuromuscul Disord (2008) 0.95
Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia. PLoS One (2008) 0.95
Allosteric communication across the native and mutated KIT receptor tyrosine kinase. PLoS Comput Biol (2012) 0.94
Protein kinase D1 stimulates proliferation and enhances tumorigenesis of MCF-7 human breast cancer cells through a MEK/ERK-dependent signaling pathway. Exp Cell Res (2012) 0.94
In vivo repopulation ability of genetically corrected bone marrow cells from Fanconi anemia patients. Proc Natl Acad Sci U S A (2006) 0.94
The neuro-glial properties of adipose-derived adult stromal (ADAS) cells are not regulated by Notch 1 and are not derived from neural crest lineage. PLoS One (2008) 0.93
The aberrant localization of oncogenic kit tyrosine kinase receptor mutants is reversed on specific inhibitory treatment. Mol Cancer Res (2009) 0.92
Endothelial expression of endocan is strongly associated with tumor progression in pituitary adenoma. Brain Pathol (2012) 0.92
Mutation D816V alters the internal structure and dynamics of c-KIT receptor cytoplasmic region: implications for dimerization and activation mechanisms. PLoS Comput Biol (2011) 0.91
Tau as a biomarker of neurodegenerative diseases. Biomark Med (2008) 0.91
Microbleeds in postmortem brains of patients with Alzheimer disease: a T2*-weighted gradient-echo 7.0 T magnetic resonance imaging study. Alzheimer Dis Assoc Disord (2013) 0.88
Differential distribution of erbB receptors in human glioblastoma multiforme: expression of erbB3 in CD133-positive putative cancer stem cells. J Neuropathol Exp Neurol (2010) 0.87
Opposite long-term regulation of c-Myc and p27Kip1 through overactivation of Raf-1 and the MEK/ERK module in proliferating human choroidal melanoma cells. Oncogene (2003) 0.87
Expression of the c-kit receptor in choroidal melanomas. Melanoma Res (2003) 0.86
Activation of the FGF2/FGFR1 autocrine loop for cell proliferation and survival in uveal melanoma cells. Invest Ophthalmol Vis Sci (2008) 0.86
Amyloid precursor protein is required for normal function of the rod and cone pathways in the mouse retina. PLoS One (2012) 0.86
Clinical, neuropathological, and biochemical characterization of the novel tau mutation P332S. J Alzheimers Dis (2012) 0.85
Sunglasses with thick temples and frame constrict temporal visual field. Optom Vis Sci (2013) 0.85
Loss of 1p, 19q, and 10q heterozygosity prospectively predicts prognosis of oligodendroglial tumors--towards individualized tumor treatment? Neuro Oncol (2010) 0.85
Shedding-generated Met receptor fragments can be routed to either the proteasomal or the lysosomal degradation pathway. Traffic (2012) 0.85
Filamin-A and Myosin VI colocalize with fibrillary Tau protein in Alzheimer's disease and FTDP-17 brains. Brain Res (2010) 0.84
Severe and rapidly evolving peripheral neuropathy revealing sporadic Creutzfeldt-Jakob disease. J Neurol (2009) 0.84
MYC and MYCN amplification can be reliably assessed by aCGH in medulloblastoma. Cancer Genet (2013) 0.84
O-Mel-Inib: a Cancéro-pôle Nord-Ouest multicenter phase II trial of high-dose imatinib mesylate in metastatic uveal melanoma. Invest New Drugs (2008) 0.84
Eye motion increases temporal visual field extent. Acta Ophthalmol (2013) 0.84
Loss of a negative feedback loop involving pea3 and cyclin d2 is required for pea3-induced migration in transformed mammary epithelial cells. Mol Cancer Res (2013) 0.83
Evidence for BRAF V600E and H3F3A K27M double mutations in paediatric glial and glioneuronal tumours. Neuropathol Appl Neurobiol (2015) 0.83
Transcriptional regulation of the human ST6GAL2 gene in cerebral cortex and neuronal cells. Glycoconj J (2009) 0.83
Masseter myosin heavy chain composition varies with mandibular asymmetry. J Craniofac Surg (2011) 0.83
CCR2/CCL2-mediated inflammation protects photoreceptor cells from amyloid-β-induced apoptosis. Neurobiol Dis (2011) 0.83
VP22 light controlled delivery of oligonucleotides to ocular cells in vitro and in vivo. Mol Vis (2005) 0.83
Prematurely senescent ARPE-19 cells display features of age-related macular degeneration. Free Radic Biol Med (2008) 0.83
Molecular modeling of wild-type and D816V c-Kit inhibition based on ATP-competitive binding of ellipticine derivatives to tyrosine kinases. J Med Chem (2005) 0.82
Chemical modification of coumarin dimer and HIV-1 integrase inhibitory activity. Chem Pharm Bull (Tokyo) (2002) 0.82
Transpupillary thermotherapy (TTT) with short duration laser exposures induce heat shock protein (HSP) hyperexpression on choroidoretinal layers. Lasers Surg Med (2003) 0.82
Juvenile frontotemporal dementia with parkinsonism associated with tau mutation G389R. J Alzheimers Dis (2013) 0.82
Bilateral temporal glioma presenting as a paraneoplastic limbic encephalitis with pure cognitive impairment. Neurologist (2009) 0.82
Suppression of α5 gene expression is closely related to the tumorigenic properties of uveal melanoma cell lines. Pigment Cell Melanoma Res (2011) 0.82
Status of RASSF1A in uveal melanocytes and melanoma cells. Mol Cancer Res (2011) 0.81
Distinct effects of inflammation on gliosis, osmohomeostasis, and vascular integrity during amyloid beta-induced retinal degeneration. Aging Cell (2012) 0.80
Pin1: a therapeutic target in Alzheimer neurodegeneration. J Mol Neurosci (2002) 0.80
APP involvement in retinogenesis of mice. Acta Neuropathol (2010) 0.79
Tau pathology modulates Pin1 post-translational modifications and may be relevant as biomarker. Neurobiol Aging (2012) 0.79
Mucosal vaccines: novel strategies and applications for the control of pathogens and tumors at mucosal sites. Hum Vaccin Immunother (2014) 0.79
Microphthalmia transcription factor analysis in posterior uveal melanomas. Exp Eye Res (2003) 0.79
Loss of cerebellar granule neurons is associated with punctate but not with large focal deposits of prion protein in Creutzfeldt-Jakob disease. J Neuropathol Exp Neurol (2009) 0.78
EWS-FLI1 inhibits TNFalpha-induced NFkappaB-dependent transcription in Ewing sarcoma cells. Biochem Biophys Res Commun (2010) 0.77
Prevalence of small cerebral bleeds in patients with progressive supranuclear palsy: a neuropathological study with 7.0-Tesla magnetic resonance imaging correlates. Folia Neuropathol (2014) 0.77
Assessment of cellular actin dynamics by measurement of fluorescence anisotropy. Anal Biochem (2007) 0.77
Protein kinase D1 regulates ERα-positive breast cancer cell growth response to 17β-estradiol and contributes to poor prognosis in patients. J Cell Mol Med (2014) 0.77
Detection of Cortical Microbleeds in Postmortem Brains of Patients with Lewy Body Dementia: A 7.0-Tesla Magnetic Resonance Imaging Study with Neuropathological Correlates. Eur Neurol (2015) 0.77
Prevalence of cerebrovascular lesions in patients with Lewy body dementia: a neuropathological study. Clin Neurol Neurosurg (2012) 0.77