David M Underhill

Author PubWeight™ 50.97‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J Exp Med 2003 7.38
2 Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis. Science 2012 5.34
3 Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity 2012 5.08
4 Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments. EMBO J 2005 4.18
5 Activation of the innate immune receptor Dectin-1 upon formation of a 'phagocytic synapse'. Nature 2011 3.32
6 Dectin-1 stimulation by Candida albicans yeast or zymosan triggers NFAT activation in macrophages and dendritic cells. J Immunol 2007 2.73
7 Staphylococcus aureus evades lysozyme-based peptidoglycan digestion that links phagocytosis, inflammasome activation, and IL-1beta secretion. Cell Host Microbe 2010 2.49
8 Dectin-1 and TLRs permit macrophages to distinguish between different Aspergillus fumigatus cellular states. J Immunol 2006 2.43
9 Differential use of CARD9 by dectin-1 in macrophages and dendritic cells. J Immunol 2009 2.23
10 Beta-glucan recognition by the innate immune system. Immunol Rev 2009 2.03
11 Fungal Recognition by TLR2 and Dectin-1. Handb Exp Pharmacol 2008 1.35
12 Paired Ig-like receptors bind to bacteria and shape TLR-mediated cytokine production. J Immunol 2007 1.29
13 Generation of diversity in the innate immune system: macrophage heterogeneity arises from gene-autonomous transcriptional probability of individual inducible genes. J Immunol 2002 1.28
14 Dectin-1-triggered recruitment of light chain 3 protein to phagosomes facilitates major histocompatibility complex class II presentation of fungal-derived antigens. J Biol Chem 2012 1.23
15 Leishmania major activates IL-1 alpha expression in macrophages through a MyD88-dependent pathway. Microbes Infect 2002 1.07
16 Phagosomal degradation increases TLR access to bacterial ligands and enhances macrophage sensitivity to bacteria. J Immunol 2011 1.05
17 Cutting edge: FYCO1 recruitment to dectin-1 phagosomes is accelerated by light chain 3 protein and regulates phagosome maturation and reactive oxygen production. J Immunol 2014 1.03
18 Mechanisms of Fc receptor and dectin-1 activation for phagocytosis. Traffic 2012 1.00
19 Detection of a TLR2 agonist by hematopoietic stem and progenitor cells impacts the function of the macrophages they produce. Eur J Immunol 2013 1.00
20 Inhibitory receptor paired Ig-like receptor B is exploited by Staphylococcus aureus for virulence. J Immunol 2012 0.89
21 Adaptor protein Lnk inhibits c-Fms-mediated macrophage function. J Leukoc Biol 2010 0.87
22 Striking a balance: fungal commensalism versus pathogenesis. Curr Opin Microbiol 2013 0.86
23 A pair of 9s: it's in the CARDs. Nat Immunol 2007 0.84
24 Failure to induce IFN-β production during Staphylococcus aureus infection contributes to pathogenicity. J Immunol 2012 0.82
25 β-Glucan signaling connects phagocytosis to autophagy. Glycobiology 2013 0.76
26 Host-microbe interactions: fungi. Curr Opin Microbiol 2008 0.75