Published in Ultrasound Med Biol on July 01, 2012
Ultrasound-mediated blood-brain barrier disruption for targeted drug delivery in the central nervous system. Adv Drug Deliv Rev (2014) 1.34
Gene therapy for the nervous system: challenges and new strategies. Neurotherapeutics (2014) 0.98
Transcranial passive acoustic mapping with hemispherical sparse arrays using CT-based skull-specific aberration corrections: a simulation study. Phys Med Biol (2013) 0.95
Targeted gene transfer to the brain via the delivery of brain-penetrating DNA nanoparticles with focused ultrasound. J Control Release (2015) 0.84
Drug and gene delivery across the blood-brain barrier with focused ultrasound. J Control Release (2015) 0.79
The application of sparse arrays in high frequency transcranial focused ultrasound therapy: a simulation study. Med Phys (2013) 0.78
Evolving Drug Delivery Strategies to Overcome the Blood Brain Barrier. Curr Pharm Des (2016) 0.76
Novel Focused Ultrasound Gene Therapy Approach Noninvasively Restores Dopaminergic Neuron Function in a Rat Parkinson's Disease Model. Nano Lett (2017) 0.76
Blood-Brain Barrier Closure Time After Controlled Ultrasound-Induced Opening Is Independent of Opening Volume. J Ultrasound Med (2017) 0.75
Non-Viral Nucleic Acid Delivery Strategies to the Central Nervous System. Front Mol Neurosci (2016) 0.75
Emerging photoluminescence in monolayer MoS2. Nano Lett (2010) 9.26
Epidemiological serosurvey of hepatitis B in China--declining HBV prevalence due to hepatitis B vaccination. Vaccine (2009) 6.30
Direct observation of a widely tunable bandgap in bilayer graphene. Nature (2009) 5.37
Coordinated regulation of Arabidopsis thaliana development by light and gibberellins. Nature (2008) 4.71
A graphene-based broadband optical modulator. Nature (2011) 4.21
Graphene plasmonics for tunable terahertz metamaterials. Nat Nanotechnol (2011) 4.20
A novel 5-enolpyruvoylshikimate-3-phosphate (EPSP) synthase transgene for glyphosate resistance stimulates growth and fecundity in weedy rice (Oryza sativa) without herbicide. New Phytol (2013) 3.44
Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells. Cell Res (2009) 3.44
Human mammary epithelial cell transformation through the activation of phosphatidylinositol 3-kinase. Cancer Cell (2003) 3.33
Localization algorithms of Underwater Wireless Sensor Networks: a survey. Sensors (Basel) (2012) 3.26
Discovery of a mutant-selective covalent inhibitor of EGFR that overcomes T790M-mediated resistance in NSCLC. Cancer Discov (2013) 2.93
Evaluation of the impact of hepatitis B vaccination among children born during 1992-2005 in China. J Infect Dis (2009) 2.62
Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals. EMBO J (2009) 2.37
Akt signals through the mammalian target of rapamycin pathway to regulate CNS myelination. J Neurosci (2009) 2.35
Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid. Nat Med (2006) 2.35
In vitro derivation of functional insulin-producing cells from human embryonic stem cells. Cell Res (2007) 2.28
Association between vitamin D and risk of colorectal cancer: a systematic review of prospective studies. J Clin Oncol (2011) 2.24
Implication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts. J Biol Chem (2003) 2.09
Electrolytic manipulation of persulfate reactivity by iron electrodes for trichloroethylene degradation in groundwater. Environ Sci Technol (2013) 2.05
Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations. Nat Genet (2011) 2.05
Obesity and risk of colorectal cancer: a systematic review of prospective studies. PLoS One (2013) 2.02
The feasibility of using high frequency ultrasound to assess nerve ending neuropathy in patients with diabetic foot. Eur J Radiol (2012) 1.98
Complementary detection of prostate-specific antigen using In2O3 nanowires and carbon nanotubes. J Am Chem Soc (2005) 1.97
A murine model of isolated cardiac steatosis leads to cardiomyopathy. Hypertension (2011) 1.90
Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion. PLoS Biol (2006) 1.89
A class of selective antibacterials derived from a protein kinase inhibitor pharmacophore. Proc Natl Acad Sci U S A (2009) 1.82
Pro12Ala polymorphism in the PPARG gene contributes to the development of diabetic nephropathy in Chinese type 2 diabetic patients. Diabetes Care (2009) 1.82
Crystal structure of human histone lysine-specific demethylase 1 (LSD1). Proc Natl Acad Sci U S A (2006) 1.80
Highly efficient and specific genome editing in silkworm using custom TALENs. PLoS One (2012) 1.80
Long-term retinal function and structure rescue using capsid mutant AAV8 vector in the rd10 mouse, a model of recessive retinitis pigmentosa. Mol Ther (2010) 1.75
Single-molecule imaging reveals target-search mechanisms during DNA mismatch repair. Proc Natl Acad Sci U S A (2012) 1.72
Activation of dormant ovarian follicles to generate mature eggs. Proc Natl Acad Sci U S A (2010) 1.66
miR-150 as a potential biomarker associated with prognosis and therapeutic outcome in colorectal cancer. Gut (2011) 1.66
Human circulating microRNA-1 and microRNA-126 as potential novel indicators for acute myocardial infarction. Int J Biol Sci (2012) 1.63
Response of human REV1 to different DNA damage: preferential dCMP insertion opposite the lesion. Nucleic Acids Res (2002) 1.63
trans-Lesion synthesis past bulky benzo[a]pyrene diol epoxide N2-dG and N6-dA lesions catalyzed by DNA bypass polymerases. J Biol Chem (2002) 1.60
Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases. Structure (2009) 1.59
Hemoglobin levels in Qinghai-Tibet: different effects of gender for Tibetans vs. Han. J Appl Physiol (1985) (2004) 1.59
Electroretinographic effects of an intravitreal injection of triamcinolone in rabbit retina. Arch Ophthalmol (2005) 1.58
Selective functionalization of In2O3 nanowire mat devices for biosensing applications. J Am Chem Soc (2005) 1.57
Maintaining the end: roles of telomere proteins in end-protection, telomere replication and length regulation. Mutat Res (2011) 1.56
Imaging the homogeneous nucleation during the melting of superheated colloidal crystals. Science (2012) 1.56
Identification of miRs-143 and -145 that is associated with bone metastasis of prostate cancer and involved in the regulation of EMT. PLoS One (2011) 1.55
Altered NADH/NAD+ ratio mediates coresistance to isoniazid and ethionamide in mycobacteria. Antimicrob Agents Chemother (2005) 1.53
Double-stranded RNA-dependent protein kinase phosphorylation of the alpha-subunit of eukaryotic translation initiation factor 2 mediates apoptosis. J Biol Chem (2006) 1.53
Therapeutic implications of a human neutralizing antibody to the macrophage-stimulating protein receptor tyrosine kinase (RON), a c-MET family member. Cancer Res (2006) 1.52
Mechanism of catheter thrombosis: comparison of the antithrombotic activities of fondaparinux, enoxaparin, and heparin in vitro and in vivo. Blood (2011) 1.51
High-resolution functional magnetic resonance imaging mapping of noxious heat and tactile activations along the central sulcus in New World monkeys. Pain (2010) 1.50
Probing electronic transitions in individual carbon nanotubes by Rayleigh scattering. Science (2004) 1.49
Increased dietary fat promotes islet amyloid formation and beta-cell secretory dysfunction in a transgenic mouse model of islet amyloid. Diabetes (2003) 1.49
Human CST promotes telomere duplex replication and general replication restart after fork stalling. EMBO J (2012) 1.47
Lead poisoning in China: a nightmare from industrialisation. Lancet (2011) 1.47
Comprehensive molecular diagnosis of 179 Leber congenital amaurosis and juvenile retinitis pigmentosa patients by targeted next generation sequencing. J Med Genet (2013) 1.47
Arsenite interacts selectively with zinc finger proteins containing C3H1 or C4 motifs. J Biol Chem (2011) 1.45
Inducing late phase of infarct protection in skeletal muscle by remote preconditioning: efficacy and mechanism. Am J Physiol Regul Integr Comp Physiol (2005) 1.45
One-step, room temperature, colorimetric detection of mercury (Hg2+) using DNA/nanoparticle conjugates. J Am Chem Soc (2008) 1.43
Arabidopsis sigma factor binding proteins are activators of the WRKY33 transcription factor in plant defense. Plant Cell (2011) 1.43
Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1. Proc Natl Acad Sci U S A (2004) 1.42
Stable liquid water droplet on a water monolayer formed at room temperature on ionic model substrates. Phys Rev Lett (2009) 1.41
Effects of temperature on the development and population growth of the sycamore lace bug, Corythucha ciliata. J Insect Sci (2011) 1.41
Circulating MicroRNA-146a and MicroRNA-21 Predict Left Ventricular Remodeling after ST-Elevation Myocardial Infarction. Cardiology (2015) 1.41
Clinical and magnetic resonance imaging manifestations of neurosarcoidosis. Semin Arthritis Rheum (2005) 1.41
Structure-guided inhibitor design for human FAAH by interspecies active site conversion. Proc Natl Acad Sci U S A (2008) 1.41
gamma-Cyclodextrin: a review on enzymatic production and applications. Appl Microbiol Biotechnol (2007) 1.39
Environmental adaptation: genomic analysis of the piezotolerant and psychrotolerant deep-sea iron reducing bacterium Shewanella piezotolerans WP3. PLoS One (2008) 1.38
Hippo signaling disruption and Akt stimulation of ovarian follicles for infertility treatment. Proc Natl Acad Sci U S A (2013) 1.38
Activities of human DNA polymerase kappa in response to the major benzo[a]pyrene DNA adduct: error-free lesion bypass and extension synthesis from opposite the lesion. DNA Repair (Amst) (2002) 1.37
A new strategy for septal ablation with transendocardial ethanol injection using a multifunctional intracardiac echocardiography catheter: a feasibility study in canines. Catheter Cardiovasc Interv (2011) 1.37
Generation of homogeneous PDX1(+) pancreatic progenitors from human ES cell-derived endoderm cells. J Mol Cell Biol (2009) 1.36
Simian virus 40 large T antigen disrupts genome integrity and activates a DNA damage response via Bub1 binding. J Virol (2008) 1.35
Transcript-level annotation of Affymetrix probesets improves the interpretation of gene expression data. BMC Bioinformatics (2007) 1.35
Robot-assisted versus conventional laparoscopic surgery for colorectal disease, focusing on rectal cancer: a meta-analysis. Ann Surg Oncol (2012) 1.35
Nucleosome-free region dominates histone acetylation in targeting SWR1 to promoters for H2A.Z replacement. Cell (2013) 1.35
Derivation and characterization of hepatic progenitor cells from human embryonic stem cells. PLoS One (2009) 1.33
Potential role of metabolomics apporoaches in the area of traditional Chinese medicine: as pillars of the bridge between Chinese and Western medicine. J Pharm Biomed Anal (2011) 1.33
Next-generation sequencing-based molecular diagnosis of a Chinese patient cohort with autosomal recessive retinitis pigmentosa. Invest Ophthalmol Vis Sci (2013) 1.32
ACE2 and Ang-(1-7) confer protection against development of diabetic retinopathy. Mol Ther (2011) 1.32
Change in hepatitis B virus large surface antigen variant prevalence 13 years after implementation of a universal vaccination program in China. J Virol (2013) 1.31
Eya1-Six1 interaction is sufficient to induce hair cell fate in the cochlea by activating Atoh1 expression in cooperation with Sox2. Dev Cell (2012) 1.30
Fiber-based wearable electronics: a review of materials, fabrication, devices, and applications. Adv Mater (2014) 1.29
A proposed OB-fold with a protein-interaction surface in Candida albicans telomerase protein Est3. Nat Struct Mol Biol (2008) 1.29
AAV-mediated cone rescue in a naturally occurring mouse model of CNGA3-achromatopsia. PLoS One (2012) 1.28
Association of candidate genetic variations with gastric cardia adenocarcinoma in Chinese population: a multiple interaction analysis. Carcinogenesis (2010) 1.28
Role of DNA polymerase eta in the bypass of abasic sites in yeast cells. Nucleic Acids Res (2004) 1.28
Transcript profiling and identification of molecular markers for early microspore embryogenesis in Brassica napus. Plant Physiol (2007) 1.27
Controlling inelastic light scattering quantum pathways in graphene. Nature (2011) 1.27
Encapsulated cell-based intraocular delivery of ciliary neurotrophic factor in normal rabbit: dose-dependent effects on ERG and retinal histology. Invest Ophthalmol Vis Sci (2004) 1.27
Docking studies and model development of tea polyphenol proteasome inhibitors: applications to rational drug design. Proteins (2004) 1.26
High-intensity focused ultrasound (HIFU): effective and safe therapy for hepatocellular carcinoma adjacent to major hepatic veins. Eur Radiol (2008) 1.26
Estrogen attenuates left ventricular and cardiomyocyte hypertrophy by an estrogen receptor-dependent pathway that increases calcineurin degradation. Circ Res (2008) 1.26
Metabolomics: towards understanding traditional Chinese medicine. Planta Med (2010) 1.24
99mTc-3PRGD2 for integrin receptor imaging of lung cancer: a multicenter study. J Nucl Med (2012) 1.23
Nanofabricated racks of aligned and anchored DNA substrates for single-molecule imaging. Langmuir (2010) 1.23
Changes of organic acid exudation and rhizosphere pH in rice plants under chromium stress. Environ Pollut (2007) 1.22
Maternal control of seed size by EOD3/CYP78A6 in Arabidopsis thaliana. Plant J (2012) 1.22
Synthetic analogs of green tea polyphenols as proteasome inhibitors. Mol Med (2002) 1.22
An improved multistate empirical valence bond model for aqueous proton solvation and transport. J Phys Chem B (2007) 1.22
Pre-ovulatory LH/hCG surge decreases C-type natriuretic peptide secretion by ovarian granulosa cells to promote meiotic resumption of pre-ovulatory oocytes. Hum Reprod (2011) 1.21