Douglas H Smith

Author PubWeight™ 82.58‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Inflammation and white matter degeneration persist for years after a single traumatic brain injury. Brain 2013 3.87
2 Traumatic brain injury and amyloid-β pathology: a link to Alzheimer's disease? Nat Rev Neurosci 2010 2.34
3 Axonal pathology in traumatic brain injury. Exp Neurol 2012 2.20
4 Multiple proteins implicated in neurodegenerative diseases accumulate in axons after brain trauma in humans. Exp Neurol 2007 2.15
5 Widespread τ and amyloid-β pathology many years after a single traumatic brain injury in humans. Brain Pathol 2011 2.11
6 Extreme stretch growth of integrated axons. J Neurosci 2004 1.76
7 Long-term accumulation of amyloid-beta, beta-secretase, presenilin-1, and caspase-3 in damaged axons following brain trauma. Am J Pathol 2004 1.63
8 Biomarkers of mild traumatic brain injury in cerebrospinal fluid and blood. Nat Rev Neurol 2013 1.60
9 Traumatic axonal injury induces proteolytic cleavage of the voltage-gated sodium channels modulated by tetrodotoxin and protease inhibitors. J Neurosci 2004 1.55
10 Mechanical breaking of microtubules in axons during dynamic stretch injury underlies delayed elasticity, microtubule disassembly, and axon degeneration. FASEB J 2009 1.52
11 A lack of amyloid beta plaques despite persistent accumulation of amyloid beta in axons of long-term survivors of traumatic brain injury. Brain Pathol 2008 1.46
12 Neutralizing the neurotoxic effects of exogenous and endogenous tPA. Nat Neurosci 2006 1.38
13 Traumatic axonal injury results in biphasic calpain activation and retrograde transport impairment in mice. J Cereb Blood Flow Metab 2003 1.26
14 Partial interruption of axonal transport due to microtubule breakage accounts for the formation of periodic varicosities after traumatic axonal injury. Exp Neurol 2011 1.26
15 Thalamic nuclei after human blunt head injury. J Neuropathol Exp Neurol 2006 1.24
16 Common data elements in radiologic imaging of traumatic brain injury. J Magn Reson Imaging 2010 1.23
17 Development of transplantable nervous tissue constructs comprised of stretch-grown axons. J Neurosci Methods 2005 1.23
18 In-vitro approaches for studying blast-induced traumatic brain injury. J Neurotrauma 2009 1.23
19 Coagulopathy in traumatic brain injury. Neurocrit Care 2004 1.20
20 Long-term survival and outgrowth of mechanically engineered nervous tissue constructs implanted into spinal cord lesions. Tissue Eng 2006 1.20
21 Long-term accumulation of amyloid-beta in axons following brain trauma without persistent upregulation of amyloid precursor protein genes. J Neuropathol Exp Neurol 2002 1.18
22 Calpain mediates proteolysis of the voltage-gated sodium channel alpha-subunit. J Neurosci 2009 1.14
23 Mild traumatic brain injury and diffuse axonal injury in swine. J Neurotrauma 2011 1.14
24 Sodium channelopathy induced by mild axonal trauma worsens outcome after a repeat injury. J Neurosci Res 2009 1.14
25 Stretch-grown axons retain the ability to transmit active electrical signals. FEBS Lett 2006 1.12
26 Neurogenesis and glial proliferation persist for at least one year in the subventricular zone following brain trauma in rats. J Neurotrauma 2003 1.11
27 A device to study the initiation and propagation of calcium transients in cultured neurons after mechanical stretch. Ann Biomed Eng 2004 1.08
28 Biomechanics of concussion. Clin Sports Med 2011 1.08
29 Thromboembolism and delayed cerebral ischemia after subarachnoid hemorrhage: an autopsy study. Neurosurgery 2006 1.06
30 Effect of acute calcium influx after mechanical stretch injury in vitro on the viability of hippocampal neurons. J Neurotrauma 2004 1.06
31 Association between intravascular microthrombosis and cerebral ischemia in traumatic brain injury. Neurosurgery 2004 1.05
32 Red blood cells-coupled tPA prevents impairment of cerebral vasodilatory responses and tissue injury in pediatric cerebral hypoxia/ischemia through inhibition of ERK MAPK activation. J Cereb Blood Flow Metab 2009 1.02
33 Signaling, delivery and age as emerging issues in the benefit/risk ratio outcome of tPA For treatment of CNS ischemic disorders. J Neurochem 2010 0.98
34 Chronic ibuprofen administration worsens cognitive outcome following traumatic brain injury in rats. Exp Neurol 2006 0.98
35 Acute and chronically increased immunoreactivity to phosphorylation-independent but not pathological TDP-43 after a single traumatic brain injury in humans. Acta Neuropathol 2011 0.97
36 Biomaterials in the repair of sports injuries. Nat Mater 2012 0.95
37 Long-term survival and integration of transplanted engineered nervous tissue constructs promotes peripheral nerve regeneration. Tissue Eng Part A 2009 0.95
38 Intravascular coagulation: a major secondary insult in nonfatal traumatic brain injury. J Neurosurg 2002 0.94
39 A neprilysin polymorphism and amyloid-beta plaques after traumatic brain injury. J Neurotrauma 2009 0.94
40 Erythrocyte-bound tissue plasminogen activator is neuroprotective in experimental traumatic brain injury. J Neurotrauma 2009 0.93
41 Blood-Brain Barrier Disruption Is an Early Event That May Persist for Many Years After Traumatic Brain Injury in Humans. J Neuropathol Exp Neurol 2015 0.93
42 Mechanisms of calpain mediated proteolysis of voltage gated sodium channel α-subunits following in vitro dynamic stretch injury. J Neurochem 2012 0.93
43 Imipramine treatment improves cognitive outcome associated with enhanced hippocampal neurogenesis after traumatic brain injury in mice. J Neurotrauma 2011 0.92
44 tPA-S481A prevents neurotoxicity of endogenous tPA in traumatic brain injury. J Neurotrauma 2012 0.87
45 Dendritic alterations after dynamic axonal stretch injury in vitro. Exp Neurol 2010 0.87
46 Differential responses in three thalamic nuclei in moderately disabled, severely disabled and vegetative patients after blunt head injury. Brain 2004 0.86
47 Harvested human neurons engineered as live nervous tissue constructs: implications for transplantation. Laboratory investigation. J Neurosurg 2008 0.86
48 Microthrombosis after experimental subarachnoid hemorrhage: time course and effect of red blood cell-bound thrombin-activated pro-urokinase and clazosentan. Exp Neurol 2011 0.86
49 Evidence That the Blood Biomarker SNTF Predicts Brain Imaging Changes and Persistent Cognitive Dysfunction in Mild TBI Patients. Front Neurol 2013 0.86
50 Hypertonic saline resuscitation of hemorrhagic shock does not decrease in vivo neutrophil interactions with endothelium in the blood-brain microcirculation. J Trauma 2011 0.85
51 Establishment of human ovarian serous carcinomas cell lines in serum free media. Methods 2012 0.85
52 Patterns of early emotional and neuropsychological sequelae after mild traumatic brain injury. J Neurotrauma 2014 0.85
53 Neuroprotective effects of progesterone in traumatic brain injury: blunted in vivo neutrophil activation at the blood-brain barrier. Am J Surg 2013 0.84
54 Microtissue engineered constructs with living axons for targeted nervous system reconstruction. Tissue Eng Part A 2012 0.84
55 Blast-induced color change in photonic crystals corresponds with brain pathology. J Neurotrauma 2011 0.83
56 Updating memory after mild traumatic brain injury and orthopedic injuries. J Neurotrauma 2013 0.83
57 Hemostatic and neuroprotective effects of human recombinant activated factor VII therapy after traumatic brain injury in pigs. Exp Neurol 2008 0.83
58 Neural tissue engineering for neuroregeneration and biohybridized interface microsystems in vivo (Part 2). Crit Rev Biomed Eng 2011 0.82
59 Developing a tissue-engineered neural-electrical relay using encapsulated neuronal constructs on conducting polymer fibers. J Neural Eng 2008 0.82
60 Neural engineering to produce in vitro nerve constructs and neurointerface. Neurosurgery 2007 0.82
61 Similar effects of hypertonic saline and mannitol on the inflammation of the blood-brain barrier microcirculation after brain injury in a mouse model. J Trauma Acute Care Surg 2012 0.81
62 Traumatic brain injury induces biphasic upregulation of ApoE and ApoJ protein in rats. J Neurosci Res 2005 0.80
63 Spatiotemporal distribution of spectrin breakdown products induced by anoxia in adult rat optic nerve in vitro. J Cereb Blood Flow Metab 2006 0.80
64 Inhibition of Nogo-66 receptor 1 enhances recovery of cognitive function after traumatic brain injury in mice. J Neurotrauma 2013 0.79
65 The separate roles of calcium and mechanical forces in mediating cell death in mechanically injured neurons. Biorheology 2003 0.79
66 A novel neuroprosthetic interface with the peripheral nervous system using artificially engineered axonal tracts. Neurol Res 2008 0.79
67 Does enoxaparin interfere with HMGB1 signaling after TBI? A potential mechanism for reduced cerebral edema and neurologic recovery. J Trauma Acute Care Surg 2016 0.79
68 Head motions while riding roller coasters: implications for brain injury. Am J Forensic Med Pathol 2009 0.78
69 Enoxaparin ameliorates post-traumatic brain injury edema and neurologic recovery, reducing cerebral leukocyte endothelial interactions and vessel permeability in vivo. J Trauma Acute Care Surg 2015 0.78
70 Color changing photonic crystals detect blast exposure. Neuroimage 2010 0.78
71 Acute treatment with MgSO4 attenuates long-term hippocampal tissue loss after brain trauma in the rat. J Neurosci Res 2004 0.77
72 Isolation of cancer stem like cells from human adenosquamous carcinoma of the lung supports a monoclonal origin from a multipotential tissue stem cell. PLoS One 2013 0.77
73 Allotransplanted neurons used to repair peripheral nerve injury do not elicit overt immunogenicity. PLoS One 2012 0.77
74 Bionic connections. Sci Am 2013 0.76
75 Multichannel activity propagation across an engineered axon network. J Neural Eng 2017 0.75
76 Unfractionated heparin after TBI reduces in vivo cerebrovascular inflammation, brain edema and accelerates cognitive recovery. J Trauma Acute Care Surg 2016 0.75
77 Neuropathological Characteristics of Brachial Plexus Avulsion Injury With and Without Concomitant Spinal Cord Injury. J Neuropathol Exp Neurol 2016 0.75
78 Early Heparin Administration After TBI: Prolonged Cognitive Recovery Associated With Reduced Cerebral Edema and Neutrophil Sequestration. J Trauma Acute Care Surg 2017 0.75
79 Apo E genotype not associated with intravascular coagulation in traumatic brain injury. Neurosci Lett 2005 0.75