Bioreactors to influence stem cell fate: augmentation of mesenchymal stem cell signaling pathways via dynamic culture systems.

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🔗 View Article (PMC 3461086)

Published in Biochim Biophys Acta on June 15, 2012

Authors

Andrew B Yeatts1, Daniel T Choquette, John P Fisher

Author Affiliations

1: Fischell Department of Bioengineering, University of Maryland, College Park, MD 20742, USA.

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Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription. Nature (1998) 4.13

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