Published in FEBS Lett on February 28, 2012
Beyond TGFβ: roles of other TGFβ superfamily members in cancer. Nat Rev Cancer (2013) 1.67
Transforming growth factor β inhibits bone morphogenetic protein-induced transcription through novel phosphorylated Smad1/5-Smad3 complexes. Mol Cell Biol (2012) 1.11
Development of an ALK2-biased BMP type I receptor kinase inhibitor. ACS Chem Biol (2013) 0.99
Chordin forms a self-organizing morphogen gradient in the extracellular space between ectoderm and mesoderm in the Xenopus embryo. Proc Natl Acad Sci U S A (2013) 0.95
Postsynaptic glutamate receptors regulate local BMP signaling at the Drosophila neuromuscular junction. Development (2013) 0.90
A gradient of Bmp7 specifies the tonotopic axis in the developing inner ear. Nat Commun (2014) 0.87
Spatial patterning of BMP-2 and BMP-7 on biopolymeric films and the guidance of muscle cell fate. Biomaterials (2014) 0.86
Ancient and diverged TGF-β signaling components in Nasonia vitripennis. Dev Genes Evol (2014) 0.83
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Fine-tuned shuttles for bone morphogenetic proteins. Curr Opin Genet Dev (2013) 0.82
The ventral to dorsal BMP activity gradient in the early zebrafish embryo is determined by graded expression of BMP ligands. Dev Biol (2013) 0.82
Repulsive guidance molecules (RGMs) and neogenin in bone morphogenetic protein (BMP) signaling. Mol Reprod Dev (2013) 0.82
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Diversity is in my veins: role of bone morphogenetic protein signaling during venous morphogenesis in zebrafish illustrates the heterogeneity within endothelial cells. Arterioscler Thromb Vasc Biol (2014) 0.81
Coordinate post-transcriptional repression of Dpp-dependent transcription factors attenuates signal range during development. Development (2015) 0.80
Calcineurin signaling regulates neural induction through antagonizing the BMP pathway. Neuron (2014) 0.80
BMP signaling in telencephalic neural cell specification and maturation. Front Cell Neurosci (2013) 0.80
The neogenin/DCC homolog UNC-40 promotes BMP signaling via the RGM protein DRAG-1 in C. elegans. Development (2013) 0.79
A Novel, Noncanonical BMP Pathway Modulates Synapse Maturation at the Drosophila Neuromuscular Junction. PLoS Genet (2016) 0.79
Bone Regeneration from PLGA Micro-Nanoparticles. Biomed Res Int (2015) 0.78
Organizer-derived Bmp2 is required for the formation of a correct Bmp activity gradient during embryonic development. Nat Commun (2014) 0.78
Promotion of bone morphogenetic protein signaling by tetraspanins and glycosphingolipids. PLoS Genet (2015) 0.77
Pentagone internalises glypicans to fine-tune multiple signalling pathways. Elife (2016) 0.76
Dual Role of Jun N-Terminal Kinase Activity in Bone Morphogenetic Protein-Mediated Drosophila Ventral Head Development. Genetics (2015) 0.76
Effects of miR-146a on the osteogenesis of adipose-derived mesenchymal stem cells and bone regeneration. Sci Rep (2017) 0.75
BMP-SMAD signalling output is highly regionalized in cardiovascular and lymphatic endothelial networks. BMC Dev Biol (2016) 0.75
The Contribution of Spatial and Temporal Molecular Networks in the Induction of Long-term Memory and Its Underlying Synaptic Plasticity. AIMS Neurosci (2016) 0.75
The dual role of BMP4 in adipogenesis and metabolism. Adipocyte (2017) 0.75
SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7. Mol Pharmacol (2002) 8.89
TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility. Nat Rev Mol Cell Biol (2007) 6.34
New insights into TGF-beta-Smad signalling. Trends Biochem Sci (2004) 6.13
Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility. Nat Cell Biol (2009) 4.39
Alterations in components of the TGF-beta superfamily signaling pathways in human cancer. Cytokine Growth Factor Rev (2005) 4.05
Tgf-beta superfamily signaling in embryonic development and homeostasis. Dev Cell (2009) 3.51
Nucleocytoplasmic shuttling of Smads 2, 3, and 4 permits sensing of TGF-beta receptor activity. Mol Cell (2002) 3.10
How the Smads regulate transcription. Int J Biochem Cell Biol (2007) 2.46
Smad4 dependency defines two classes of transforming growth factor {beta} (TGF-{beta}) target genes and distinguishes TGF-{beta}-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses. Mol Cell Biol (2005) 2.41
Transforming growth factor beta-induced Smad1/5 phosphorylation in epithelial cells is mediated by novel receptor complexes and is essential for anchorage-independent growth. Mol Cell Biol (2008) 2.27
Controlling long-term signaling: receptor dynamics determine attenuation and refractory behavior of the TGF-β pathway. Sci Signal (2013) 2.11
Kinetic analysis of Smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor beta-dependent nuclear accumulation of Smads. Mol Cell Biol (2005) 1.84
Attenuation of the TGF-beta-Smad signaling pathway in pancreatic tumor cells confers resistance to TGF-beta-induced growth arrest. Oncogene (2003) 1.76
Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system. Proc Natl Acad Sci U S A (2008) 1.75
Analysis of Smad nucleocytoplasmic shuttling in living cells. J Cell Sci (2004) 1.70
Beyond TGFβ: roles of other TGFβ superfamily members in cancer. Nat Rev Cancer (2013) 1.67
Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation. Mol Cell Biol (2007) 1.65
SNW1 is a critical regulator of spatial BMP activity, neural plate border formation, and neural crest specification in vertebrate embryos. PLoS Biol (2011) 1.48
Recruitment of TIF1γ to chromatin via its PHD finger-bromodomain activates its ubiquitin ligase and transcriptional repressor activities. Mol Cell (2011) 1.43
Kinesin-mediated transport of Smad2 is required for signaling in response to TGF-beta ligands. Dev Cell (2007) 1.36
A new class of small molecule inhibitor of BMP signaling. PLoS One (2013) 1.36
Smads orchestrate specific histone modifications and chromatin remodeling to activate transcription. EMBO J (2006) 1.30
Epithelial to mesenchymal transition in Madin-Darby canine kidney cells is accompanied by down-regulation of Smad3 expression, leading to resistance to transforming growth factor-beta-induced growth arrest. J Biol Chem (2002) 1.26
Different Smad2 partners bind a common hydrophobic pocket in Smad2 via a defined proline-rich motif. EMBO J (2002) 1.20
The RhoA activator GEF-H1/Lfc is a transforming growth factor-beta target gene and effector that regulates alpha-smooth muscle actin expression and cell migration. Mol Biol Cell (2010) 1.18
A novel Cripto-related protein reveals an essential role for EGF-CFCs in Nodal signalling in Xenopus embryos. Dev Biol (2006) 1.12
Stoichiometry of active smad-transcription factor complexes on DNA. J Biol Chem (2002) 1.12
Transforming growth factor β inhibits bone morphogenetic protein-induced transcription through novel phosphorylated Smad1/5-Smad3 complexes. Mol Cell Biol (2012) 1.11
Two highly related regulatory subunits of PP2A exert opposite effects on TGF-beta/Activin/Nodal signalling. Development (2008) 1.11
Recognition of phosphorylated-Smad2-containing complexes by a novel Smad interaction motif. Mol Cell Biol (2004) 1.06
Molecular and functional consequences of Smad4 C-terminal missense mutations in colorectal tumour cells. Biochem J (2004) 1.05
Smad3 protein levels are modulated by Ras activity and during the cell cycle to dictate transforming growth factor-beta responses. J Biol Chem (2009) 1.02
Hypoxia-activated Smad3-specific dephosphorylation by PP2A. J Biol Chem (2009) 1.00
A novel Xenopus Smad-interacting forkhead transcription factor (XFast-3) cooperates with XFast-1 in regulating gastrulation movements. Development (2002) 0.96
Arkadia regulates tumor metastasis by modulation of the TGF-β pathway. Cancer Res (2013) 0.91
A BMP regulatory network controls ectodermal cell fate decisions at the neural plate border. Development (2013) 0.83
Mice develop normally in the absence of Smad4 nucleocytoplasmic shuttling. Biochem J (2007) 0.82
The ventral to dorsal BMP activity gradient in the early zebrafish embryo is determined by graded expression of BMP ligands. Dev Biol (2013) 0.82
Small RNA profiling of Xenopus embryos reveals novel miRNAs and a new class of small RNAs derived from intronic transposable elements. Genome Res (2013) 0.80
Studying Smad2 intranuclear diffusion dynamics by mathematical modelling of FRAP experiments. Integr Biol (Camb) (2011) 0.76
An N-terminally truncated Smad2 protein can partially compensate for loss of full-length Smad2. Biochem J (2009) 0.75
Signaling and gradients: what's going down? Curr Opin Cell Biol (2012) 0.75