TNF receptor-associated factor 6 in advanced non-small cell lung cancer: clinical and prognostic implications.

PubWeight™: 0.83‹?›

🔗 View Article (PMID 22736025)

Published in J Cancer Res Clin Oncol on June 27, 2012

Authors

Hui Liu1, Tiantuo Zhang, Jin Ye, Hongtao Li, Jing Huang, Xiaodong Li, Benquan Wu, Xubing Huang, Jinghui Hou

Author Affiliations

1: Division of Pulmonary and Critical Care, Department of Internal Medicine, The Third Affiliated Hospital of Sun Yat-sen University, No 600 Tianhe street, Guangzhou 510630, China. huiliu_sums@yahoo.com.cn

Articles cited by this

Reporting results of cancer treatment. Cancer (1981) 28.83

Tumor necrosis factor receptor-associated factors (TRAFs). Oncogene (2001) 2.98

Tumor-infiltrating gammadelta T cells suppress T and dendritic cell function via mechanisms controlled by a unique toll-like receptor signaling pathway. Immunity (2007) 2.94

TRAF6 is a T cell-intrinsic negative regulator required for the maintenance of immune homeostasis. Nat Med (2006) 2.44

TRAF6 is a critical factor for dendritic cell maturation and development. Immunity (2003) 2.36

Targeting transcription factor NF-kappaB to overcome chemoresistance and radioresistance in cancer therapy. Biochim Biophys Acta (2010) 2.08

Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy. J Exp Med (2011) 2.04

TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies. J Immunol (2000) 1.60

Growth inhibition and radiosensitization of glioblastoma and lung cancer cells by small interfering RNA silencing of tumor necrosis factor receptor-associated factor 2. Cancer Res (2008) 1.55

MicroRNA-146a downregulates NFκB activity via targeting TRAF6 and functions as a tumor suppressor having strong prognostic implications in NK/T cell lymphoma. Clin Cancer Res (2011) 1.54

TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer. J Clin Invest (2011) 1.42

The role of TRAF6 in signal transduction and the immune response. Microbes Infect (2004) 1.23

A novel mechanism for TNFR-associated factor 6-dependent CD40 signaling. J Immunol (2007) 1.17

Histological typing of lung and pleural tumours: third edition. J Clin Pathol (2001) 1.17

Modulation of life and death by the tumor necrosis factor receptor-associated factors (TRAFs). J Biochem Mol Biol (2002) 1.14

CD95 and TRAF2 promote invasiveness of pancreatic cancer cells. FASEB J (2005) 1.11

MyD88 and TNF receptor-associated factor 6 are critical signal transducers in Helicobacter pylori-infected human epithelial cells. J Immunol (2006) 1.05

TNF receptor-associated factor 6 deficiency during hemopoiesis induces Th2-polarized inflammatory disease. J Immunol (2003) 1.03

TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2. Blood (2010) 1.01

Predictive value of MMP-7 expression for response to chemotherapy and survival in patients with non-small cell lung cancer. Cancer Sci (2008) 0.96

Physiological and molecular effects of Apo2L/TRAIL and cisplatin in ovarian carcinoma cell lines. Cancer Lett (2003) 0.96

Targeting TRAfs for therapeutic intervention. Adv Exp Med Biol (2007) 0.95

Retracted Late phase activation of nuclear transcription factor kappaB by doxorubicin is mediated by interleukin-8 and induction of apoptosis via FasL. Breast Cancer Res Treat (2009) 0.91

TRAF6 directs commitment to regulatory T cells in thymocytes. Genes Cells (2011) 0.86

TRAF6 regulates cell fate decisions by inducing caspase 8-dependent apoptosis and the activation of NF-kappaB. J Biol Chem (2006) 0.85

CD40 ligand-induced carcinoma cell death: a balance between activation of TNFR-associated factor (TRAF) 3-dependent death signals and suppression of TRAF6-dependent survival signals. J Immunol (2009) 0.83

mRNA expression levels and genetic status of genes involved in the EGFR and NF-κB pathways in metastatic non-small-cell lung cancer patients. J Transl Med (2011) 0.82

CD40-mediated cell death requires TRAF6 recruitment. Immunobiology (2011) 0.81

The expression of SOCS1 and TLR4-NFkappaB pathway molecules in neoplastic cells as potential biomarker for the aggressive tumor phenotype in laryngeal carcinoma. Folia Histochem Cytobiol (2009) 0.81

Characterization of apoptosis and proliferation in esophageal carcinoma EC109 cells following siRNA-induced down-regulation of TRAF6. Mol Cell Biochem (2011) 0.79

Renal cell carcinoma: resistance to therapy, role of apoptosis, and the prognostic and therapeutic target potential of TRAF proteins. Med Hypotheses (2011) 0.75

Articles by these authors

Global variation in copy number in the human genome. Nature (2006) 57.50

Large-scale genotyping of complex DNA. Nat Biotechnol (2003) 10.00

Genome-wide detection of human copy number variations using high-density DNA oligonucleotide arrays. Genome Res (2006) 5.97

Parallel genotyping of over 10,000 SNPs using a one-primer assay on a high-density oligonucleotide array. Genome Res (2004) 5.59

High-resolution analysis of DNA copy number using oligonucleotide microarrays. Genome Res (2004) 5.24

Dynamic model based algorithms for screening and genotyping over 100 K SNPs on oligonucleotide microarrays. Bioinformatics (2005) 5.01

Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins. Proc Natl Acad Sci U S A (2007) 4.05

Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription coupling. J Clin Invest (2006) 3.72

The genomic distribution of population substructure in four populations using 8,525 autosomal SNPs. Hum Genomics (2004) 3.53

Clozapine v. chlorpromazine in treatment-naive, first-episode schizophrenia: 9-year outcomes of a randomised clinical trial. Br J Psychiatry (2011) 3.49

A Pseudomonas syringae effector inactivates MAPKs to suppress PAMP-induced immunity in plants. Cell Host Microbe (2007) 3.15

Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54. Nat Genet (2010) 2.95

Different functional roles of T1R subunits in the heteromeric taste receptors. Proc Natl Acad Sci U S A (2004) 2.85

Identification of FBL2 as a geranylgeranylated cellular protein required for hepatitis C virus RNA replication. Mol Cell (2005) 2.78

Algorithms for large-scale genotyping microarrays. Bioinformatics (2003) 2.66

Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia. Bone (2006) 2.59

Denosumab, a fully human monoclonal antibody to RANKL, inhibits bone resorption and increases BMD in knock-in mice that express chimeric (murine/human) RANKL. J Bone Miner Res (2009) 2.51

The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression. Genes Dev (2008) 2.48

A new infinite inorganic [n]catenane from silver and bis(2-methylimidazolyl)methane ligand. Chem Commun (Camb) (2006) 2.46

FGF23 neutralization improves chronic kidney disease-associated hyperparathyroidism yet increases mortality. J Clin Invest (2012) 2.41

Target identification using drug affinity responsive target stability (DARTS). Proc Natl Acad Sci U S A (2009) 2.40

Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter. Mol Cell Biol (2002) 2.35

PET/NIRF/MRI triple functional iron oxide nanoparticles. Biomaterials (2010) 2.31

A transforming metal nanocomposite with large elastic strain, low modulus, and high strength. Science (2013) 2.28

Chikungunya virus emergence is constrained in Asia by lineage-specific adaptive landscapes. Proc Natl Acad Sci U S A (2011) 2.12

Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes. Proc Natl Acad Sci U S A (2010) 2.06

Massively parallel tumor multigene sequencing to evaluate response to panitumumab in a randomized phase III study of metastatic colorectal cancer. Clin Cancer Res (2013) 2.03

Nebulin-deficient mice exhibit shorter thin filament lengths and reduced contractile function in skeletal muscle. J Cell Biol (2006) 2.00

Distinct regulatory mechanisms and functions for p53-activated and p53-repressed DNA damage response genes in embryonic stem cells. Mol Cell (2012) 1.94

T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis. Development (2005) 1.92

Histone deacetylase 3 interacts with runx2 to repress the osteocalcin promoter and regulate osteoblast differentiation. J Biol Chem (2004) 1.91

Carvedilol and its new analogs suppress arrhythmogenic store overload-induced Ca2+ release. Nat Med (2011) 1.88

Role of the CX3CR1/p38 MAPK pathway in spinal microglia for the development of neuropathic pain following nerve injury-induced cleavage of fractalkine. Brain Behav Immun (2006) 1.88

Hypoxia-inducible factor 1-alpha reduces infarction and attenuates progression of cardiac dysfunction after myocardial infarction in the mouse. J Am Coll Cardiol (2005) 1.85

Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis. Biomed Pharmacother (2010) 1.82

Sclerostin and Dickkopf-1 as therapeutic targets in bone diseases. Endocr Rev (2012) 1.82

Probing red cell membrane cholesterol movement with cyclodextrin. Biophys J (2002) 1.80

A phenotypic small-molecule screen identifies an orphan ligand-receptor pair that regulates neural stem cell differentiation. Chem Biol (2007) 1.78

Allelic dosage analysis with genotyping microarrays. Biochem Biophys Res Commun (2005) 1.78

Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Proc Natl Acad Sci U S A (2005) 1.76

Orchidectomy, but not ovariectomy, regulates angiotensin II-induced vascular diseases in apolipoprotein E-deficient mice. Endocrinology (2004) 1.76

Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake. Cell Metab (2006) 1.74

Protocadherin FAT1 binds Ena/VASP proteins and is necessary for actin dynamics and cell polarization. EMBO J (2004) 1.73

Pulsed oxidation and biological evolution in the Ediacaran Doushantuo Formation. Proc Natl Acad Sci U S A (2008) 1.73

Proteolytic activation of sterol regulatory element-binding protein induced by cellular stress through depletion of Insig-1. J Biol Chem (2004) 1.72

Apolipoprotein E on hepatitis C virion facilitates infection through interaction with low-density lipoprotein receptor. Virology (2009) 1.72

Mesenchymal stem cells use integrin beta1 not CXC chemokine receptor 4 for myocardial migration and engraftment. Mol Biol Cell (2007) 1.72

Structure of a Shigella effector reveals a new class of ubiquitin ligases. Nat Struct Mol Biol (2008) 1.71

Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase. Nat Biotechnol (2010) 1.71

Deregulated miR-155 promotes Fas-mediated apoptosis in human intervertebral disc degeneration by targeting FADD and caspase-3. J Pathol (2011) 1.70

Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of nonfractured bones. J Bone Miner Res (2011) 1.70

A pooling-deconvolution strategy for biological network elucidation. Nat Methods (2006) 1.68

Band-like transport, high electron mobility and high photoconductivity in all-inorganic nanocrystal arrays. Nat Nanotechnol (2011) 1.66

The Arabidopsis nitrate transporter NRT1.8 functions in nitrate removal from the xylem sap and mediates cadmium tolerance. Plant Cell (2010) 1.66

Novel functions of the phosphatidylinositol metabolic pathway discovered by a chemical genomics screen with wortmannin. Proc Natl Acad Sci U S A (2003) 1.61

Real-time reverse transcriptase-polymerase chain reaction quantification of West Nile virus transmitted by Culex pipiens quinquefasciatus. Am J Trop Med Hyg (2004) 1.60

How cholesterol homeostasis is regulated by plasma membrane cholesterol in excess of phospholipids. Proc Natl Acad Sci U S A (2004) 1.60

miR-340 inhibition of breast cancer cell migration and invasion through targeting of oncoprotein c-Met. Cancer (2011) 1.60

Transcriptional patterns, biomarkers and pathways characterizing nasopharyngeal carcinoma of Southern China. J Transl Med (2008) 1.57

Poly[[bis-[μ(2)-8-ethyl-5-oxo-2-(piperazin-1-yl)-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxyl-ato]manganese(II)] dihydrate]. Acta Crystallogr Sect E Struct Rep Online (2008) 1.56

Whole brain white matter changes revealed by multiple diffusion metrics in multiple sclerosis: a TBSS study. Eur J Radiol (2011) 1.55

Molecular imaging of drug-modulated protein-protein interactions in living subjects. Cancer Res (2004) 1.55

Sterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78. J Biol Chem (2006) 1.54

Molecular mechanism for the umami taste synergism. Proc Natl Acad Sci U S A (2008) 1.53

Superhigh-throughput needleless electrospinning using a rotary cone as spinneret. Small (2010) 1.52

Contamination assessment of copper, lead, zinc, manganese and nickel in street dust of Baoji, NW China. J Hazard Mater (2008) 1.51

Endothelial expression of bone morphogenetic protein receptor type 1a is required for atrioventricular valve formation. Ann Thorac Surg (2008) 1.51

Tumor-derived matrix metalloproteinase-13 (MMP-13) correlates with poor prognoses of invasive breast cancer. BMC Cancer (2008) 1.50

Cell-based chemical genetic screen identifies damnacanthal as an inhibitor of HIV-1 Vpr induced cell death. Biochem Biophys Res Commun (2006) 1.48

The histone variant H3.3 regulates gene expression during lytic infection with herpes simplex virus type 1. J Virol (2008) 1.48

Abdominal aortic aneurysms: fresh insights from a novel animal model of the disease. Vasc Med (2002) 1.48

Essential role of ICAM-1/CD18 in mediating EPC recruitment, angiogenesis, and repair to the infarcted myocardium. Circ Res (2006) 1.46

Matrilysin inhibits proliferation and modulates sensitivity of lung cancer cells to FasL-mediated apoptosis. Med Oncol (2008) 1.46

Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines. J Med Chem (2011) 1.46

Knowledge and personal use of menopausal hormone therapy among Chinese obstetrician-gynecologists: results of a survey. Menopause (2014) 1.44

Bitter taste receptors influence glucose homeostasis. PLoS One (2008) 1.44

Identification of direct protein targets of small molecules. ACS Chem Biol (2010) 1.44

The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation. Genes Dev (2012) 1.43

Parallel preoptic pathways for thermoregulation. J Neurosci (2009) 1.43

Impact of 120-W 2-μm continuous wave laser vapoenucleation of the prostate on sexual function. Lasers Med Sci (2013) 1.42

Post-translational regulation of Oct4 transcriptional activity. PLoS One (2009) 1.41

A genomewide study identifies the Wnt signaling pathway as a major target of p53 in murine embryonic stem cells. Proc Natl Acad Sci U S A (2009) 1.41

Improvements of cardiac electrophysiologic stability and ventricular fibrillation threshold in rats with myocardial infarction treated with cardiac stem cells. Crit Care Med (2011) 1.39

Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin. Curr Biol (2007) 1.37

A new strategy for septal ablation with transendocardial ethanol injection using a multifunctional intracardiac echocardiography catheter: a feasibility study in canines. Catheter Cardiovasc Interv (2011) 1.37

Sclerostin antibody increases bone mass by stimulating bone formation and inhibiting bone resorption in a hindlimb-immobilization rat model. Bone (2010) 1.36

Effects of suvorexant, an orexin receptor antagonist, on sleep parameters as measured by polysomnography in healthy men. Sleep (2013) 1.35

Low-dose computed tomography image restoration using previous normal-dose scan. Med Phys (2011) 1.35

Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice. J Neurosci (2002) 1.34

Molecular mechanism of the sweet taste enhancers. Proc Natl Acad Sci U S A (2010) 1.32

Nanomechanical characterization of one-step combustion-synthesized Al(4)B(2)O(9) and Al(18)B(4)O(33) nanowires. Nano Lett (2007) 1.31

The effects of Gd3+ substitution on the crystal structure, site symmetry, and photoluminescence of Y/Eu layered rare-earth hydroxide (LRH) nanoplates. Dalton Trans (2011) 1.31

Disruption of endothelial-cell caveolin-1alpha/raft scaffolding during development of monocrotaline-induced pulmonary hypertension. Circulation (2004) 1.30

Suberoylanilide hydroxamic acid (SAHA; vorinostat) causes bone loss by inhibiting immature osteoblasts. Bone (2011) 1.30

Effectors of rapid homeostatic responses of endoplasmic reticulum cholesterol and 3-hydroxy-3-methylglutaryl-CoA reductase. J Biol Chem (2007) 1.30

Freestanding three-dimensional graphene/MnO2 composite networks as ultralight and flexible supercapacitor electrodes. ACS Nano (2012) 1.30

Variance analysis of x-ray CT sinograms in the presence of electronic noise background. Med Phys (2012) 1.30

Histone deacetylase 3 depletion in osteo/chondroprogenitor cells decreases bone density and increases marrow fat. PLoS One (2010) 1.29